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John Mendelsohn
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Journal Articles

“Personalized Cancer Therapy”: A Publicly Available Precision Oncology Resource

Katherine C. Kurnit, Ann M. Bailey, Jia Zeng, Amber M. Johnson, Md. Abu Shufean, Lauren Brusco, Beate C. Litzenburger, Nora S. Sánchez, Yekaterina B. Khotskaya, Vijaykumar Holla, Amy Simpson, Gordon B. Mills, John Mendelsohn, Elmer Bernstam, Kenna Shaw, Funda Meric-Bernstam
Journal: Cancer Research
Cancer Res (2017) 77 (21): e123–e126.
https://doi.org/10.1158/0008-5472.CAN-17-0341
Published: 01 November 2017
View articletitled, “Personalized Cancer Therapy”: A Publicly Available Precision Oncology Resource
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Includes: Multimedia, Supplementary data
Journal Articles

Commentary on “Recombinant Humanized Anti-HER2 Antibody (Herceptin) Enhances the Antitumor Activity of Paclitaxel and Doxorubicin against HER2/neu Overexpressing Human Breast Cancer Xenografts” (A Follow Up)

John Mendelsohn
Journal: Cancer Research
Cancer Res (2016) 76 (18): 5192–5194.
https://doi.org/10.1158/0008-5472.CAN-16-2269
Published: 15 September 2016
View articletitled, Commentary on “Recombinant Humanized Anti-HER2 Antibody (Herceptin) Enhances the Antitumor Activity of Paclitaxel and Doxorubicin against HER2/neu Overexpressing Human Breast Cancer Xenografts” (A Follow Up)
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Journal Articles

Abstract 668: Induction of mammary carcinoma in tetracycline-inducible cMET(T1010I) transgenic mice

Chuanwei Yang, Ana M. Gonzalez, Naoto T. Ueno, Shuying Liu, Jinsong Zhang, Gordon B. Mills, John Mendelsohn, Prahlad Ram
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 668.
https://doi.org/10.1158/1538-7445.AM2016-668
Published: 15 July 2016
View articletitled, Abstract 668: Induction of mammary carcinoma in tetracycline-inducible cMET(T1010I) transgenic mice
Journal Articles

Abstract 392: Combined targeting of MET and PI3K improves efficacy in breast cancer models with concurrent MET/PI3K aberrations

Shuying Liu, Naoto T. Ueno, Bailiang Wang, Mihai Gagea, Prahlad T. Ram, Mark Merchant, John Mendelsohn, Debasish Tripathy, Gordon B. Mills, Ana M. Gonzalez-Angulo
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 392.
https://doi.org/10.1158/1538-7445.AM2016-392
Published: 15 July 2016
View articletitled, Abstract 392: Combined targeting of MET and PI3K improves efficacy in breast cancer models with concurrent MET/PI3K aberrations
Journal Articles

Abstract PR13: Investigating the importance of low allele frequency mutations for cancer patient management

Ken Chen, Funda Meric-Bernstam, Hao Zhao, Tenghui Chen, Kenna Shaw, John Mendelsohn, Agda Eterovic, Gordon Mills
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): PR13.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-PR13
Published: 15 November 2015
View articletitled, Abstract PR13: Investigating the importance of low allele frequency mutations for cancer patient management
Journal Articles

Abstract PR05: Investigating the importance of low allele frequency mutations for cancer patient management

Ken Chen, Funda Meric-Bernstam, Hao Zhao, Tenghui Chen, Kenna Shaw, John Mendelsohn, Agda Eterovic, Gordon Mills
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): PR05.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-PR05
Published: 15 November 2015
View articletitled, Abstract PR05: Investigating the importance of low allele frequency mutations for cancer patient management
Journal Articles

Abstract 4276: T200: a high depth targeted exome sequencing platform to identify actionable alterations in FFPE solid tumor samples

Karina Eterovic, Ken Chen, Hao Zhao, Funda Meric-Bernstam, Raja Luthra, Aldape Kenneth, Mark Routbort, Scott Kopetz, Michael Davies, John de Groot, Stacy Moulder, Yong Mao, Chacha Horombe, Lin-ya Tang, Song Ping, Zhang Qingxiu, Ezzeddine Nader, Lan Zhang, Kenna M. Shaw, John Mendelsohn, Gordon B. Mills
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4276.
https://doi.org/10.1158/1538-7445.AM2014-4276
Published: 01 October 2014
View articletitled, Abstract 4276: T200: a high depth targeted exome sequencing platform to identify actionable alterations in FFPE solid tumor samples
Journal Articles

Epidermal Growth Factor Receptor (EGFR) Ubiquitination as a Mechanism of Acquired Resistance Escaping Treatment by the Anti-EGFR Monoclonal Antibody Cetuximab

Yang Lu, Xinqun Li, Ke Liang, Rodney Luwor, Zahid H. Siddik, Gordon B. Mills, John Mendelsohn, Zhen Fan
Journal: Cancer Research
Cancer Res (2007) 67 (17): 8240–8247.
https://doi.org/10.1158/0008-5472.CAN-07-0589
Published: 05 September 2007
View articletitled, Epidermal Growth Factor Receptor (EGFR) Ubiquitination as a Mechanism of Acquired Resistance Escaping Treatment by the Anti-EGFR Monoclonal Antibody Cetuximab
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Journal Articles

Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance to the anti-EGFR monoclonal antibody cetuximab

Yang Lu, Xinqun Li, Ke Liang, Rodney Luwor, Zahid Siddik, Gordon Mills, John Mendelsohn, Zhen Fan
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4082.
Published: 01 May 2007
View articletitled, Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance to the anti-EGFR monoclonal antibody cetuximab
Journal Articles

The anti-epidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

Rodney Luwor, Yang Lu, Xinqun Li, John Mendelsohn, Zhen Fan
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1192.
Published: 01 May 2005
View articletitled, The anti-epidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression
Journal Articles

Activated Extracellular Signal-regulated Kinases: Association with Epidermal Growth Factor Receptor/Transforming Growth Factor α Expression in Head and Neck Squamous Carcinoma and Inhibition by Anti-Epidermal Growth Factor Receptor Treatments

Joan Albanell, Jordi Codony-Servat, Federico Rojo, José M. Del Campo, Silvia Sauleda, Judit Anido, Guillermo Raspall, Jordi Giralt, José Roselló, Robert I. Nicholson, John Mendelsohn, José Baselga
Journal: Cancer Research
Cancer Res (2001) 61 (17): 6500–6510.
Published: 01 September 2001
View articletitled, Activated Extracellular Signal-regulated Kinases: Association with Epidermal Growth Factor Receptor/Transforming Growth Factor α Expression in Head and Neck Squamous Carcinoma and Inhibition by Anti-Epidermal Growth Factor Receptor Treatments
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Journal Articles

Recombinant Humanized Anti-HER2 Antibody (Herceptin™) Enhances the Antitumor Activity of Paclitaxel and Doxorubicin against HER2/neu Overexpressing Human Breast Cancer Xenografts

Jose Baselga, Larry Norton, Joan Albanell, Young-Mee Kim, John Mendelsohn
Journal: Cancer Research
Cancer Res (1998) 58 (13): 2825–2831.
Published: 01 July 1998
View articletitled, Recombinant Humanized Anti-HER2 Antibody (Herceptin™) Enhances the Antitumor Activity of Paclitaxel and Doxorubicin against HER2/neu Overexpressing Human Breast Cancer Xenografts
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Journal Articles

Basic Fibroblast Growth Factor Causes Growth Arrest in MCF-7 Human Breast Cancer Cells while Inducing both Mitogenic and Inhibitory G1 Events

Huisheng Wang, Mark Rubin, Eyal Fenig, Anthony DeBlasio, John Mendelsohn, Joachim Yahalom, Robert Wieder
Journal: Cancer Research
Cancer Res (1997) 57 (9): 1750–1757.
Published: 01 May 1997
View articletitled, Basic Fibroblast Growth Factor Causes Growth Arrest in MCF-7 Human Breast Cancer Cells while Inducing both Mitogenic and Inhibitory G1 Events
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Journal Articles

Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 225 Up-Regulates p27KIP1 and Induces G1 Arrest in Prostatic Cancer Cell Line DU145

Ding Peng, Zhen Fan, Yang Lu, Tony DeBlasio, Howard Scher, John Mendelsohn
Journal: Cancer Research
Cancer Res (1996) 56 (16): 3666–3669.
Published: 01 August 1996
View articletitled, Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 225 Up-Regulates p27KIP1 and Induces G1 Arrest in Prostatic Cancer Cell Line DU145
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Journal Articles

Involvement of B Lymphocytes in the Growth Inhibition of Human Pulmonary Melanoma Metastases in Athymic nu/nu Mice by an Antibody-Lymphotoxin Fusion Protein

Ralph A. Reisfeld, Stephen D. Gillies, John Mendelsohn, Nissi M. Varki, Jürgen C. Becker
Journal: Cancer Research
Cancer Res (1996) 56 (8): 1707–1712.
Published: 01 April 1996
View articletitled, Involvement of B Lymphocytes in the Growth Inhibition of Human Pulmonary Melanoma Metastases in Athymic nu/nu Mice by an Antibody-Lymphotoxin Fusion Protein
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Journal Articles

9-cis Retinoic Acid Inhibits Growth of Breast Cancer Cells and Down-Regulates Estrogen Receptor RNA and Protein

Mark Rubin, Eyal Fenig, Angelika Rosenauer, Celia Menendez-Botet, Charles Achkar, Jacqueline M. Bentel, Joachim Yahalom, John Mendelsohn, Wilson H. Miller, Jr.
Journal: Cancer Research
Cancer Res (1994) 54 (24): 6549–6556.
Published: 01 December 1994
View articletitled, 9-cis Retinoic Acid Inhibits Growth of Breast Cancer Cells and Down-Regulates Estrogen Receptor RNA and Protein
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Journal Articles

Antitumor Effect of Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies plus cis-Diamminedichloroplatinum on Well Established A431 Cell Xenografts

Zhen Fan, Jose Baselga, Hideo Masui, John Mendelsohn
Journal: Cancer Research
Cancer Res (1993) 53 (19): 4637–4642.
Published: 01 October 1993
View articletitled, Antitumor Effect of Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies plus cis-Diamminedichloroplatinum on Well Established A431 Cell Xenografts
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Journal Articles

Blockade of Epidermal Growth Factor Receptor Function by Bivalent and Monovalent Fragments of 225 Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies

Zhen Fan, Hideo Masui, Ian Altas, John Mendelsohn
Journal: Cancer Research
Cancer Res (1993) 53 (18): 4322–4328.
Published: 01 September 1993
View articletitled, Blockade of Epidermal Growth Factor Receptor Function by Bivalent and Monovalent Fragments of 225 Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies
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Journal Articles

Epidermal Growth Factor Receptor Monoclonal Antibody Inhibits Constitutive Receptor Phosphorylation, Reduces Autonomous Growth, and Sensitizes Androgen-independent Prostatic Carcinoma Cells to Tumor Necrosis Factor α

Chau-Jye Fong, Edward R. Sherwood, John Mendelsohn, Chung Lee, James M. Kozlowski
Journal: Cancer Research
Cancer Res (1992) 52 (21): 5887–5892.
Published: 01 November 1992
View articletitled, Epidermal Growth Factor Receptor Monoclonal Antibody Inhibits Constitutive Receptor Phosphorylation, Reduces Autonomous Growth, and Sensitizes Androgen-independent Prostatic Carcinoma Cells to Tumor Necrosis Factor α
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Journal Articles

Growth Regulation of Human Renal Carcinoma Cells: Role of Transforming Growth Factor α

Ian Atlas, John Mendelsohn, Jose Baselga, William R. Fair, Hideo Masui, Rakesh Kumar
Journal: Cancer Research
Cancer Res (1992) 52 (12): 3335–3339.
Published: 01 June 1992
View articletitled, Growth Regulation of Human Renal Carcinoma Cells: Role of Transforming Growth Factor α
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