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John Kuriyan
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Journal Articles

Abstract #3816: Insights into the activation mechanism of EGF receptor from the structure of the inactive kinase domain dimer

Natalia Jura, Nicholas Endres, Kate Engel, Sebastian Deindl, Xuewu Zhang, John Kuriyan
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3816.
Published: 01 May 2009
View article titled, Abstract #3816: Insights into the activation mechanism of EGF receptor from the structure of the inactive kinase domain dimer
Journal Articles

Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations

Markus A. Seeliger, Pratistha Ranjitkar, Corynn Kasap, Yibing Shan, David E. Shaw, Neil P. Shah, John Kuriyan, Dustin J. Maly
Journal: Cancer Research
Cancer Res (2009) 69 (6): 2384–2392.
https://doi.org/10.1158/0008-5472.CAN-08-3953
Published: 17 March 2009
View article titled, Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations
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Includes: Supplementary data
Journal Articles

Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680

Matthew A. Young, Neil P. Shah, Luke H. Chao, Markus Seeliger, Zdravko V. Milanov, William H. Biggs, III, Daniel K. Treiber, Hitesh K. Patel, Patrick P. Zarrinkar, David J. Lockhart, Charles L. Sawyers, John Kuriyan
Journal: Cancer Research
Cancer Res (2006) 66 (2): 1007–1014.
https://doi.org/10.1158/0008-5472.CAN-05-2788
Published: 19 January 2006
View article titled, Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680
Open the PDF for Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680 in another window
Journal Articles

Characterization of Potent Inhibitors of the Bcr-Abl and the c-Kit Receptor Tyrosine Kinases

David Wisniewski, Caryl L. Lambek, Chongyuan Liu, Annabel Strife, Darren R. Veach, Bhushan Nagar, Matthew A. Young, Thomas Schindler, William G. Bornmann, Joseph R. Bertino, John Kuriyan, Bayard Clarkson
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4244–4255.
Published: 01 August 2002
View article titled, Characterization of Potent Inhibitors of the Bcr-Abl and the c-Kit Receptor Tyrosine Kinases
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Journal Articles

Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571)

Bhushan Nagar, William G. Bornmann, Patricia Pellicena, Thomas Schindler, Darren R. Veach, W. Todd Miller, Bayard Clarkson, John Kuriyan
Journal: Cancer Research
Cancer Res (2002) 62 (15): 4236–4243.
Published: 01 August 2002
View article titled, Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571)
Open the PDF for Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571) in another window