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Journal Articles

CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility

Mulong Du, Junyi Xin, Rui Zheng, Qianyu Yuan, Zhihui Wang, Hongliang Liu, Hanting Liu, Guoshuai Cai, Demetrius Albanes, Stephen Lam, Adonina Tardon, Chu Chen, Stig E. Bojesen, Maria Teresa Landi, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, Gad Rennert, Susanne Arnold, Paul Brennan, John K. Field, Sanjay S. Shete, Loïc Le Marchand, Geoffrey Liu, Angeline S. Andrew, Lambertus A. Kiemeney, Shan Zienolddiny, Kjell Grankvist, Mikael Johansson, Neil E. Caporaso, Angela Cox, Yun-Chul Hong, Jian-Min Yuan, Matthew B. Schabath, Melinda C. Aldrich, Meilin Wang, Hongbing Shen, Feng Chen, Zhengdong Zhang, Rayjean J. Hung, Christopher I. Amos, Qingyi Wei, Philip Lazarus, David C. Christiani
Journal: Cancer Research
Cancer Res (2024) 84 (4): 616–625.
https://doi.org/10.1158/0008-5472.CAN-23-0900
Published: 15 February 2024
View article titled, CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility
Open the PDF for CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility in another window
Includes: Supplementary data
Journal Articles

Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model

Rayjean J. Hung, Matthew T. Warkentin, Yonathan Brhane, Nilanjan Chatterjee, David C. Christiani, Maria Teresa Landi, Neil E. Caporaso, Geoffrey Liu, Mattias Johansson, Demetrius Albanes, Loic Le Marchand, Adonina Tardon, Gad Rennert, Stig E. Bojesen, Chu Chen, John K. Field, Lambertus A. Kiemeney, Philip Lazarus, Shanbeth Zienolddiny, Stephen Lam, Angeline S. Andrew, Susanne M. Arnold, Melinda C. Aldrich, Heike Bickeböller, Angela Risch, Matthew B. Schabath, James D. McKay, Paul Brennan, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1607–1615.
https://doi.org/10.1158/0008-5472.CAN-20-1237
Published: 15 March 2021
View article titled, Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model
Open the PDF for Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model in another window
Includes: Supplementary data
Journal Articles

Abstract LB-053: Familial studies identify variants in the E2A transcription factor as putative risk factors for lung cancer

Claudio W. Pikielny, Anthony M. Musolf, Mariza de Andrade, Diptasri Mandal, Colette Gaba, Ping Yang, yafang Li, Ming You, Richard Wilson, Elena Y. Kupert, Marshall W. Anderson, Ann G. Schwartz, Susan M. Pinney, Ambrose I. Granizo-Mackenzie, Yanhong Liu, Ramaswamy Govindan, James McKay, Rayjean Hung, John K. Field, David C. Christiani, Joan E. Bailey-Wilson, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-053.
https://doi.org/10.1158/1538-7445.AM2019-LB-053
Published: 01 July 2019
View article titled, Abstract LB-053: Familial studies identify variants in the E2A transcription factor as putative risk factors for lung cancer
Journal Articles

Abstract 5358: Multi-omics comparative analyses of pulmonary typical carcinoids, atypical carcinoids, and large-cell neuroendocrine carcinoma

Noémie Leblay, Nicolas Alcala, David Hervás Marin, Tiffany M. Delhomme, Théo Giffon, Akram Ghantous, Amélie Chabrier, Cyrille Cuenin, Janine Altmueller, Geoffroy Durand, Catherine Voegele, Philippe Lorimier, Anne-Claire Toffart, Jules Derks, Odd Terje Brustugun, Joachim H. Clement, Joerg Saenger, John K. Field, Alex Soltermann, Gavin M. Wright, Luca Roz, Lucia Anna Muscarella, Paolo Graziano, Zdenko Herceg, Ernst-Jan Speel, Peter Nuernberg, James McKay, Nicolas Girard, Sylvie Lantuejoul, Juan Sandoval, Elisabeth Brambilla, Matthieu Foll, Lynnette Fernandez-Cuesta
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5358.
https://doi.org/10.1158/1538-7445.AM2018-5358
Published: 01 July 2018
View article titled, Abstract 5358: Multi-omics comparative analyses of pulmonary typical carcinoids, atypical carcinoids, and large-cell neuroendocrine carcinoma
Journal Articles

Abstract 4220: Liverpool healthy lung project: a primary care initiative to identify hard to reach individuals with a high risk of developing lung cancer

John K. Field, Edward S. Gaynor, Stephen W. Duffy, Katy Gardner, Cathy Hubbert, Dimitris Tsintzos, Michael W. Marcus, Lisa Jones, Rachel Avanitis, Michelle Timoney, Martin Ledson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4220.
https://doi.org/10.1158/1538-7445.AM2017-4220
Published: 01 July 2017
View article titled, Abstract 4220: Liverpool healthy lung project: a primary care initiative to identify hard to reach individuals with a high risk of developing lung cancer
Journal Articles

Abstract 2248: Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium

Pawadee Lohavanichbutr, Lori C. Sakoda, Christopher I. Amos, Susanne M. Arnold, David C. Christiani, Michael P. Davies, John K. Field, Eric B. Haura, Rayjean J. Hung, Takashi Kohno, Maria Teresa Landi, Geoffrey Liu, Yi Liu, Michael W. Marcus, Grainne M. O'Kane, Matthew B. Schabath, Kouya Shiraishi, Stacey A. Slone, Adonina Tardón, Ping Yang, Kazushi Yoshida, Ruyang Zhang, Xuchen Zong, Noel S. Weiss, Chu Chen
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2248.
https://doi.org/10.1158/1538-7445.AM2017-2248
Published: 01 July 2017
View article titled, Abstract 2248: Common <em>TDP1</em> polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium
Journal Articles

Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium

Linda Kachuri, Mattias Johansson, Paul Brennan, Phillip Haycock, Geoffrey Liu, Maria Teresa Landi, David C. Christiani, Neil E. Caporaso, Xifeng Wu, Melinda C. Aldrich, Demetrius Albanes, Adonina Tardón, Gad Rennert, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, Heike Bickeböller, Dawn Teare, Lambertus A. Kiemeney, Stig E. Bojesen, John K. Field, Aage Haugen, Stephen Lam, Loic Le Marchand, Matthew B. Schabath, Angeline S. Andrew, Jonas Manjer, Philip Lazarus, Susanne M. Arnold, Valérie Gaborieau, Richard Martin, Caroline Relton, George Davey Smith, Christopher I. Amos, James D. McKay, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2292.
https://doi.org/10.1158/1538-7445.AM2017-2292
Published: 01 July 2017
View article titled, Abstract 2292: Lung function and lung cancer risk: a Mendelian randomization study of UK Biobank cohort and the International Lung Cancer Consortium
Journal Articles

Abstract 3458: UK lung cancer screening trial (UKLS) cost effectiveness: similarities with the NLST high-risk quintiles

David Whynes, Stephen W. Duffy, David R. Baldwin, Anand Devaraj, John K. Field
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3458.
https://doi.org/10.1158/1538-7445.AM2016-3458
Published: 15 July 2016
View article titled, Abstract 3458: UK lung cancer screening trial (UKLS) cost effectiveness: similarities with the NLST high-risk quintiles
Journal Articles

Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk

Linda Kachuri, George Davey Smith, Geoffrey Liu, Maria Teresa Landi, David C. Christiani, Neil E. Caporaso, James D. McKay, Xifeng Wu, Melinda C. Aldrich, Gad Rennert, Dawn Teare, Chu Chen, Gary E. Goodman, Jennifer A. Doherty, John K. Field, Lambertus A. Kiemeney, Adonina Tardón, Aage Haugen, Stephen Lam, Loic Le Marchand, Matthew B. Schabath, Angeline S. Andrew, Mattias Johansson, Jonas Manjer, Philip Lazarus, Susanne Arnold, Gordon Fehringer, Xuchen Zong, Paul Brennan, Stig E. Bojesen, Christopher I. Amos, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 817.
https://doi.org/10.1158/1538-7445.AM2016-817
Published: 15 July 2016
View article titled, Abstract 817: Mendelian randomization and mediation analysis of 5p15.33, telomere length and lung cancer risk
Journal Articles

Abstract 4602: Exome sequencing of UKLS lung cancer CT screened early stage cancers

Russell Hyde, Michael Davies, Martin Ledson, John A. Holemans, Richard D. Page, John Gosney, David R. Baldwin, Anand Devaraj, David M. Hansell, Stephen W. Duffy, John K. Field
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4602.
https://doi.org/10.1158/1538-7445.AM2015-4602
Published: 01 August 2015
View article titled, Abstract 4602: Exome sequencing of UKLS lung cancer CT screened early stage cancers
Journal Articles

Abstract 1531: Cross-entity mutation analysis of lung neuroendocrine tumors sheds light into their molecular origin and identifies new therapeutic targets

Lynnette Fernandez-Cuesta, Martin Peifer, Xin Lu, Danila Seidel, Thomas Zander, Frauke Leenders, Luka Ozretić, Odd-Terje Brustugun, John K. Field, Gavin Wright, Benjamin Solomon, Reinhard Buettner, Christian Brambilla, Elisabeth Brambilla, Roman K. Thomas
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1531.
https://doi.org/10.1158/1538-7445.AM2014-1531
Published: 01 October 2014
View article titled, Abstract 1531: Cross-entity mutation analysis of lung neuroendocrine tumors sheds light into their molecular origin and identifies new therapeutic targets
Journal Articles

Abstract 3631: United Kingdom lung cancer screening trial (UKLS): First 88897 approaches.

John K. Field, David Baldwin, Anand Devaraj, Kate Brain, Tim Eisen, John Holemans, Martin Ledson, Nicholas Screaton, Robert C. Rintoul, Ghasem Yadegarfar, Chris Hands, Fiona E. McRonald, Kate Lifford, David Whynes, Keith Kerr, Richard Page, Mahesh Parmar, David Weller, David Whynes, Paula Williamson, David Hansell, Stephen W. Duffy
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3631.
https://doi.org/10.1158/1538-7445.AM2013-3631
Published: 15 April 2013
View article titled, Abstract 3631: United Kingdom lung cancer screening trial (UKLS): First 88897 approaches.
Journal Articles

DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer

Georgios Nikolaidis, Olaide Y. Raji, Soultana Markopoulou, John R. Gosney, Julie Bryan, Chris Warburton, Martin Walshaw, John Sheard, John K. Field, Triantafillos Liloglou
Journal: Cancer Research
Cancer Res (2012) 72 (22): 5692–5701.
https://doi.org/10.1158/0008-5472.CAN-12-2309
Published: 14 November 2012
View article titled, DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer
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Includes: Supplementary data
Journal Articles

Abstract 4133: MicroRNAs for early detection of lung cancer

Naiara Bediaga, Michael PA Davies, Olaide Y. Raji, Ana Alfirevic, Triantafillos Liloglou, John K. Field
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4133.
https://doi.org/10.1158/1538-7445.AM2012-4133
Published: 15 April 2012
View article titled, Abstract 4133: MicroRNAs for early detection of lung cancer
Journal Articles

Abstract 3571: UKLS - United Kingdom Lung Cancer Screening Trial

John K. Field, David Baldwin, Duffy W. Stephen, Anand Devaraj, David M. Hansell
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3571.
https://doi.org/10.1158/1538-7445.AM2012-3571
Published: 15 April 2012
View article titled, Abstract 3571: UKLS - United Kingdom Lung Cancer Screening Trial
Journal Articles

Abstract 4158: SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma

John K. Field, Olaide Raji, Triantafillos Liloglou
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4158.
https://doi.org/10.1158/1538-7445.AM2011-4158
Published: 15 April 2011
View article titled, Abstract 4158: SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma
Journal Articles

Abstract 1898: The Liverpool Lung Project risk model: An independent validation and clinical utility in primary care

John K. Field, Olaide Y. Raji, Adrian Cassidy, Stephen W. Duffy, Stuart G. Baker, David C. Christiani
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1898.
https://doi.org/10.1158/1538-7445.AM2011-1898
Published: 15 April 2011
View article titled, Abstract 1898: The Liverpool Lung Project risk model: An independent validation and clinical utility in primary care
Journal Articles

Abstract 163: DTMETH: A novel method for increased length quantitative CpG methylation analysis

Triantafillos Liloglou, Anastasia Filia, Alexandros Daskalos, Georgios Nikolaidis, Helen Bottomley, Peter N. Ma, Britta Finkelnburg, John K. Field
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 163.
https://doi.org/10.1158/1538-7445.AM10-163
Published: 15 April 2010
View article titled, Abstract 163: DTMETH: A novel method for increased length quantitative CpG methylation analysis
Journal Articles

Abstract 2893: Incorporation of the SEZ6L SNP into The Liverpool Lung Project Risk Prediction Model

John K. Field, Olaide Raji, Olorunsola F. Abgaje, Adrian Cassidy, Stephen W. Duffy
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2893.
https://doi.org/10.1158/1538-7445.AM10-2893
Published: 15 April 2010
View article titled, Abstract 2893: Incorporation of the SEZ6L SNP into The Liverpool Lung Project Risk Prediction Model
Journal Articles

Abstract 4826: International Lung Cancer Consortium: Pooled analysis of previous lung diseases and lung cancer risk

Darren R. Brenner, Paolo Boffetta, Eric J. Duell, Heike Bickeböller, Albert Rosenberger, Joshua E. Muscat, Ping Yang, Erich Wichmann, Ann G. Schwartz, Anne Tjønneland, Søren Friis, Loic LeMarchand, Zuo-Feng Zhang, Philip Lazarus, John K. Field, John R. McLaughlin, John Wiencke, Monica Neri, Qing Lan, Irene Orlow, Bernard J. Park, Rayjean J. Hung
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4826.
https://doi.org/10.1158/1538-7445.AM10-4826
Published: 15 April 2010
View article titled, Abstract 4826: International Lung Cancer Consortium: Pooled analysis of previous lung diseases and lung cancer risk