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Journal Articles

Abstract PO4-08-06: Causal Relationships and Familial Aggregation of Mammogram Risk Scores: Insights from Breast Cancer in Twins and Families

Zhoufeng Ye, Shuai Li, Gill Dite, Tuong Nguyen, Robert MacInnis, John Hopper
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-08-06.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-08-06
Published: 02 May 2024
View article titled, Abstract PO4-08-06: Causal Relationships and Familial Aggregation of Mammogram Risk Scores: Insights from Breast Cancer in Twins and Families
Journal Articles

Abstract PS10-01: Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Pathogenic Variants in BRCA1 and BRCA2

Kelly-Anne Phillips, Joanne Kotsopoulos, Susan Domchek, James Chamberlain, Julie Bassett, Amber Aeilts, Irene Andrulis, Saundra Buys, Wanda Cui, Mary Daly, Andrea Eisen, William Foulkes, Michael Friedlander, Jacek Gronwald, John Hopper, Esther John, Beth Karlan, Raymond Kim, Jan Lubiński, Kelly Metcalfe, Katherine Nathanson, Christian F. Singer, Heather Symecko, Nadine Tung, Steven Narod, Mary Beth Terry, Roger Milne
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS10-01.
https://doi.org/10.1158/1538-7445.SABCS23-PS10-01
Published: 02 May 2024
View article titled, Abstract PS10-01: Hormonal Contraception and Breast Cancer Risk for Carriers of Germline Pathogenic Variants in BRCA1 and BRCA2
Journal Articles

Abstract 224: Evidence for a shared genetic basis between breast cancer and mammographic density phenotypes

Hongjie Chen, Julie Douglas, William Gordon, Deborah Thompson, Fergus Couch, Peter Fasching, Per Hall, John Hopper, Gertraud Maskarenic, Marina Pollan, Jennifer Stone, Rulla Tamimi, Sara Lindstroem
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 224.
https://doi.org/10.1158/1538-7445.AM2018-224
Published: 01 July 2018
View article titled, Abstract 224: Evidence for a shared genetic basis between breast cancer and mammographic density phenotypes
Journal Articles

Abstract 1322: A meta-analysis of genome-wide association studies identifies novel loci that influence breast cancer prognosis

Latha Kadalayil, Sofia Khan, Heli Nevanlinna, Peter A. Fasching, Fergus J. Couch, John Hopper, Jianjun Liu, Tom Maishman, Lorraine Durcan, Carl Bloomqvist, Andy Collins, Dianna Eccles, William Tapper
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1322.
https://doi.org/10.1158/1538-7445.AM2017-1322
Published: 01 July 2017
View article titled, Abstract 1322: A meta-analysis of genome-wide association studies identifies novel loci that influence breast cancer prognosis
Journal Articles

Abstract 4276: Oral contraceptive use and breast cancer risk: a cohort study of BRCA1 and BRCA2 mutation carriers

Lieske H. Schrijver, Hakan Olsson, Antonis Antoniou, Roger Milne, Kelly Phillips, Nadine Andrieu, Douglas Easton, David Goldgar, Christoph Engel, Karin Kast, Marie-Jose Blom, Thea Mooij, John Hopper, Floor Van Leeuwen, Mary-Beth Terry, Matti Rookus, IBCCS, kConFab, BCFR
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4276.
https://doi.org/10.1158/1538-7445.AM2017-4276
Published: 01 July 2017
View article titled, Abstract 4276: Oral contraceptive use and breast cancer risk: a cohort study of <em>BRCA1</em> and <em>BRCA2</em> mutation carriers
Journal Articles

Abstract 1975: The 3D chromatin structure of the PTHLH region comprises a dynamic hierarchical looping complex that approximates the protein-coding genes and facilitates promoter and enhancer promiscuity

Adam N. Freeman, Michael A. Henderson, Miroslaw K. Kapuscinski, John Hopper, T John Martin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1975.
https://doi.org/10.1158/1538-7445.AM2016-1975
Published: 15 July 2016
View article titled, Abstract 1975: The 3D chromatin structure of the PTHLH region comprises a dynamic hierarchical looping complex that approximates the protein-coding genes and facilitates promoter and enhancer promiscuity
Journal Articles

Abstract A1-10: The iCOGS breast cancer GWAS reveals 4 unique signals in the PTHLH region in patients of European origin

Adam N. Freeman, T John Martin, Michael A. Henderson, Enes Makalic, Miroslaw K. Kapuscinski, Daniel F. Schmidt, John Hopper
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_1): A1-10.
https://doi.org/10.1158/1538-7445.TRANSCAGEN-A1-10
Published: 15 November 2015
View article titled, Abstract A1-10: The iCOGS breast cancer GWAS reveals 4 unique signals in the PTHLH region in patients of European origin
Journal Articles

Abstract B1-52: Analysis of the iCOGS breast cancer GWAS reveals 4 unique signals in the PTHLH region in patients of European origin

Adam N. Freeman, T John Martin, Michael A. Henderson, Enes Makalic, Miroslaw K. Kapuscinski, Daniel F. Schmidt, John Hopper
Journal: Cancer Research
Cancer Res (2015) 75 (22_Supplement_2): B1-52.
https://doi.org/10.1158/1538-7445.COMPSYSBIO-B1-52
Published: 15 November 2015
View article titled, Abstract B1-52: Analysis of the iCOGS breast cancer GWAS reveals 4 unique signals in the PTHLH region in patients of European origin
Journal Articles

Abstract 1098: Epistasis analysis of the PTHLH region in European subjects of the iCOGS breast cancer GWAS suggest multiple genes may be implicated in its role in breast cancer

Adam N. Freeman, Michael A. Henderson, T John Martin, Enes Makalic, Miroslaw K. Kapuscinski, Daniel Schmidt, John Hopper
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1098.
https://doi.org/10.1158/1538-7445.AM2015-1098
Published: 01 August 2015
View article titled, Abstract 1098: Epistasis analysis of the PTHLH region in European subjects of the iCOGS breast cancer GWAS suggest multiple genes may be implicated in its role in breast cancer
Journal Articles

Abstract 2782: Risk loci for a breast-colon cancer phenotype: results from a genome-wide association study

Mala Pande, Aron Joon, Sanjay Shete, Abenaa M. Brewster, Cathy Eng, Wei V. Chen, Habibul Ahsan, Irene L. Andrulis, Esther M. John, Yi Lin, Polly A. Newcomb, Noralane M. Lindor, Christopher I. Amos, John Hopper, Patrick M. Lynch
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2782.
https://doi.org/10.1158/1538-7445.AM2015-2782
Published: 01 August 2015
View article titled, Abstract 2782: Risk loci for a breast-colon cancer phenotype: results from a genome-wide association study
Journal Articles

Abstract LB-282: Transethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

Hansong Wang, Terrilea Burnett, Suminori Kono, Christopher Haiman, Motoki Iwasaki, Lynne Wilkens, Lenora Loo, David Van Den Berg, Laurence Kolonel, Brian Henderson, Temitope Keku, Robert Sandler, Lisa Signorello, William Blot, Polly Newcomb, Mala Pande, Christopher Amos, Dee West, Stéphane Bézieau, Sonja Berndt, Brent Zanke, Li Hsu, Noralane Lindor, Robert Haile, John Hopper, Mark Jenkins, Steven Gallinger, Graham Casey, Stephanie Stenzel, Fredrick Schumacher, Ulrike Peters, Stephen Gruber, Shoichiro Tsugane, Dan Stram, Loic L. Marchand
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-282.
https://doi.org/10.1158/1538-7445.AM2014-LB-282
Published: 01 October 2014
View article titled, Abstract LB-282: Transethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A
Journal Articles

Abstract 2930: Novel colorectal cancer loci in multiplex-proficient mismatch repair families

Julie M. Cunningham, Mine Cicek, Fridley Brooke, Daniel Serie, William Bamlet, Brenda Diergaarde, Robert Haile, Loic Le Marchand, Theodore Kontriris, Ban Younghusband, Steven Gallinger, Polly Newcomb, John Hopper, Mark Jenkins, Graham Casey, Frederick Schumacher, Zhu Chen, Allyson Templeton, Ingrid Winship, Roger Green, Macrae Finlay, Susan Parry, Graeme Young, Joanne Young, Daniel Buchanan, Duncan Thomas, D. Timothy Bishop, Noralane Lindor, Stephen Thibodeau, John Potter, Ellen Goode, Colon CFR.
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2930.
https://doi.org/10.1158/1538-7445.AM2012-2930
Published: 15 April 2012
View article titled, Abstract 2930: Novel colorectal cancer loci in multiplex-proficient mismatch repair families
Journal Articles

Confirmation of Linkage to and Localization of Familial Colon Cancer Risk Haplotype on Chromosome 9q22

Courtney Gray-McGuire, Kishore Guda, Indra Adrianto, Chee Paul Lin, Leanna Natale, John D. Potter, Polly Newcomb, Elizabeth M. Poole, Cornelia M. Ulrich, Noralane Lindor, Ellen L. Goode, Brooke L. Fridley, Robert Jenkins, Loic Le Marchand, Graham Casey, Robert Haile, John Hopper, Mark Jenkins, Joanne Young, Daniel Buchanan, Steve Gallinger, Mark Adams, Susan Lewis, Joseph Willis, Robert Elston, Sanford D. Markowitz, Georgia L. Wiesner
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5409–5418.
https://doi.org/10.1158/0008-5472.CAN-10-0188
Published: 30 June 2010
View article titled, Confirmation of Linkage to and Localization of Familial Colon Cancer Risk Haplotype on Chromosome 9q22
Open the PDF for Confirmation of Linkage to and Localization of Familial Colon Cancer Risk Haplotype on Chromosome 9q22 in another window
Includes: Supplementary data
Journal Articles

Abstract 798: Adenomas in Lynch syndrome: Diagnostically useful

Christophe Rosty, Michael Walsh, Daniel Buchanan, Sven Arnold, Mark Clendenning, Rhiannon Walters, John Hopper, Mark Jenkins, Jeremy Jass, Joanne Young
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 798.
https://doi.org/10.1158/1538-7445.AM10-798
Published: 15 April 2010
View article titled, Abstract 798: Adenomas in Lynch syndrome: Diagnostically useful
Journal Articles

Abstract 32: Lynch syndrome-associated breast cancers: Clinicopathological characteristics of a case series from the Colon CFR

Christophe Rosty, Michael Walsh, Margaret Cummings, Daniel Buchanan, Sven Arnold, Diane McKeone, Rhiannon Walters, John Hopper, Mark Jenkins, Amanda Spurdle, Michael McGuckin, Sunil Lakhani, Joanne Young
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 32.
https://doi.org/10.1158/1538-7445.AM10-32
Published: 15 April 2010
View article titled, Abstract 32: Lynch syndrome-associated breast cancers: Clinicopathological characteristics of a case series from the Colon CFR
Journal Articles

Abstract 3862: Identification of a novel genetic variant in the KLK3 gene which predisposes to prostate cancer

Zsofia Kote-Jarai, Ali Amin Al Olama, Daniel Leongamornlert, Malgorzata Tymrakiewicz, Ed Saunders, Michelle Guy, Nadiya Mahmud, Graham Giles, Gianluca Severi, John Hopper, Freddy Hamdy, David Neal, Jenny Donovan, Kenneth Muir, Jonathan Morrison, The UK Genetic Prostate Cancer Study Collaborators/BAUS Section of Oncology, Douglas Easton, Rosalind Eeles
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3862.
https://doi.org/10.1158/1538-7445.AM10-3862
Published: 15 April 2010
View article titled, Abstract 3862: Identification of a novel genetic variant in the <em>KLK3</em> gene which predisposes to prostate cancer
Journal Articles

Abstract #88: Identification of a further novel profile of SNPs associated with prostate cancer

Rosalind Eeles, Zsofia Kote-Jarai, Douglas Easton, Michelle Guy, Ali Al Olama, Jonathan Morrison, Graham Giles, John Hopper, Gianluca Severi, Freddie Hamdy, Jennifer Donovan, David Neal, Kenneth Muir, Artitaya Lophatananon, The UKGPCS and The PRACTICAL Consortium
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 88.
Published: 01 May 2009
View article titled, Abstract #88: Identification of a further novel profile of SNPs associated with prostate cancer
Journal Articles

Abstract #1904: The association of global gene expression in human colon tumors with germline variation at rs6983267 on 8q24 suggests that this SNP is an eQTL hotspot

Gordon Okimoto, Maarit Tiirikainen, Naveen Babbar, Jenny Poynter, Lenora Loo, Michael Loomis, John Hopper, Mark Jenkins, Steven Gallinger, Stephen Thibodeau, Robert Haile, Graham Casey, David Duggan, Loïc Le Marchand
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1904.
Published: 01 May 2009
View article titled, Abstract #1904: The association of global gene expression in human colon tumors with germline variation at rs6983267 on 8q24 suggests that this SNP is an eQTL hotspot
Journal Articles

Breast cancer genetics in perspective: Results from population-based studies

John Hopper
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): SY36-02.
Published: 01 May 2008
View article titled, Breast cancer genetics in perspective: Results from population-based studies
Journal Articles

Identification of multiple novel prostate cancer susceptibility loci by a genome-wide association study

Rosalind Eeles, Zsofia Kote-Jarai, Graham Giles, Ali Al Olama, Michelle Guy, Stephen Edwards, Shani Mulholland, Sarah Jugurnauth, Daniel Leongamornlert, Malgorzata Tymrakiewicz, Sameer Jhavar, David Dearnaley, Jonathan Morrison, Helen Field, Melissa Southey, Gianluca Severi, Jennifer Donovan, Freddie Hamdy, Kenneth Muir, Colin Cooper, Dallas English, John Hopper, David Neal, Douglas Easton
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5810.
Published: 01 May 2008
View article titled, Identification of multiple novel prostate cancer susceptibility loci by a genome-wide association study