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John Galivan
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Journal Articles

Multifactorial Resistance to 5,10-Dideazatetrahydrofolic Acid in Cell Lines Derived from Human Lymphoblastic Leukemia CCRF-CEM

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Giuseppe Pizzorno, Barbara A. Moroson, Arlene R. Cashmore, Orsolina Russello, Jennifer R. Mayer, John Galivan, Marlene A. Bunni, David G. Priest, G. Peter Beardsley
Journal: Cancer Research
Cancer Res (1995) 55 (3): 566–573.
Published: 01 February 1995
View article titled, Multifactorial Resistance to 5,10-Dideazatetrahydrofolic Acid in Cell Lines Derived from Human Lymphoblastic Leukemia CCRF-CEM
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Journal Articles

Acquisition of Resistance to Antifolates Caused by Enhanced γ-Glutamyl Hydrolase Activity

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Myung S. Rhee, Ying Wang, M. Gopal Nair, John Galivan
Journal: Cancer Research
Cancer Res (1993) 53 (10): 2227–2230.
Published: 01 May 1993
View article titled, Acquisition of Resistance to Antifolates Caused by Enhanced γ-Glutamyl Hydrolase Activity
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Journal Articles

Secretion of γ-Glutamyl Hydrolase in Vitro

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Brigid M. O'Connor, Robert F. Rotundo, Zenia Nimec, John J. McGuire, John Galivan
Journal: Cancer Research
Cancer Res (1991) 51 (15): 3874–3881.
Published: 01 August 1991
View article titled, Secretion of γ-Glutamyl Hydrolase in Vitro
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Journal Articles

Role of Substrate Depletion in the Inhibition of Thymidylate Biosynthesis by the Dihydrofolate Reductase Inhibitor Trimetrexate in Cultured Hepatoma Cells

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Myung S. Rhee, Malgorzata Balinska, Marlene Bunni, David G. Priest, Gladys F. Maley, Frank Maley, John Galivan
Journal: Cancer Research
Cancer Res (1990) 50 (13): 3979–3984.
Published: 01 July 1990
View article titled, Role of Substrate Depletion in the Inhibition of Thymidylate Biosynthesis by the Dihydrofolate Reductase Inhibitor Trimetrexate in Cultured Hepatoma Cells
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Journal Articles

Biochemical and Growth Inhibitory Effects of the erythro and threo Isomers of γ-Fluoromethotrexate, a Methotrexate Analogue Defective in Polyglutamylation

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John J. McGuire, Michael Graber, Nicholas Licato, Claudius Vincenz, James K. Coward, Zenia Nimec, John Galivan
Journal: Cancer Research
Cancer Res (1989) 49 (16): 4517–4525.
Published: 01 August 1989
View article titled, Biochemical and Growth Inhibitory Effects of the erythro and threo Isomers of γ-Fluoromethotrexate, a Methotrexate Analogue Defective in Polyglutamylation
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Journal Articles

Role of Folylpolyglutamate Synthetase in the Regulation of Methotrexate Polyglutamate Formation in H35 Hepatoma Cells

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Thomas B. Johnson, M. G. Nair, John Galivan
Journal: Cancer Research
Cancer Res (1988) 48 (9): 2426–2431.
Published: 01 May 1988
View article titled, Role of Folylpolyglutamate Synthetase in the Regulation of Methotrexate Polyglutamate Formation in H35 Hepatoma Cells
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Journal Articles

Antifolate Drug Interactions: Enhancement of Growth Inhibition Due to the Antipurine 5,10-Dideazatetrahydrofolic Acid by the Lipophilic Dihydrofolate Reductase Inhibitors Metoprine and Trimetrexate

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John Galivan, Zenia Nimec, Myung Rhee, Diane Boschelli, Arnold L. Oronsky, Suresh S. Kerwar
Journal: Cancer Research
Cancer Res (1988) 48 (9): 2421–2425.
Published: 01 May 1988
View article titled, Antifolate Drug Interactions: Enhancement of Growth Inhibition Due to the Antipurine 5,10-Dideazatetrahydrofolic Acid by the Lipophilic Dihydrofolate Reductase Inhibitors Metoprine and Trimetrexate
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Journal Articles

Synergistic Growth Inhibition of Rat Hepatoma Cells Exposed in Vitro to N10-Propargyl-5,8-dideazafolate with Methotrexate or the Lipophilic Antifolates Trimetrexate or Metoprine

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John Galivan, Zenia Nimec, Myung Rhee
Journal: Cancer Research
Cancer Res (1987) 47 (20): 5256–5260.
Published: 01 October 1987
View article titled, Synergistic Growth Inhibition of Rat Hepatoma Cells Exposed in Vitro to N10-Propargyl-5,8-dideazafolate with Methotrexate or the Lipophilic Antifolates Trimetrexate or Metoprine
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Journal Articles

Conversion of Methotrexate to 7-Hydroxymethotrexate and 7-Hydroxymethotrexate Polyglutamates in Cultured Rat Hepatic Cells

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Myung S. Rhee, John Galivan
Journal: Cancer Research
Cancer Res (1986) 46 (8): 3793–3797.
Published: 01 August 1986
View article titled, Conversion of Methotrexate to 7-Hydroxymethotrexate and 7-Hydroxymethotrexate Polyglutamates in Cultured Rat Hepatic Cells
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Journal Articles

Hepatic Parenchymal Cell Glutamylation of Methotrexate Studied in Monolayer Culture

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John Galivan, Aiga Pupons, Myung S. Rhee
Journal: Cancer Research
Cancer Res (1986) 46 (2): 670–675.
Published: 01 February 1986
View article titled, Hepatic Parenchymal Cell Glutamylation of Methotrexate Studied in Monolayer Culture
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Journal Articles

Effects of Folinic Acid on Hepatoma Cells Containing Methotrexate Polyglutamates

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John Galivan, Zenia Nimec
Journal: Cancer Research
Cancer Res (1983) 43 (2): 551–555.
Published: 01 February 1983
View article titled, Effects of Folinic Acid on Hepatoma Cells Containing Methotrexate Polyglutamates
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Journal Articles

Efflux of Methotrexate and Its Polyglutamate Derivatives from Hepatic Cells in Vitro

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Malgorzata Balińska, John Galivan, James K. Coward
Journal: Cancer Research
Cancer Res (1981) 41 (7): 2751–2756.
Published: 01 July 1981
View article titled, Efflux of Methotrexate and Its Polyglutamate Derivatives from Hepatic Cells in Vitro
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Journal Articles

5-Methyltetrahydrofolate Transport by Hepatoma Cells and Methotrexate-resistant Sublines in Culture

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John Galivan
Journal: Cancer Research
Cancer Res (1981) 41 (5): 1757–1762.
Published: 01 May 1981
View article titled, 5-Methyltetrahydrofolate Transport by Hepatoma Cells and Methotrexate-resistant Sublines in Culture
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Journal Articles

Transport and Metabolism of Methotrexate in Normal and Resistant Cultured Rat Hepatoma Cells

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John Galivan
Journal: Cancer Research
Cancer Res (1979) 39 (3): 735–743.
Published: 01 March 1979
View article titled, Transport and Metabolism of Methotrexate in Normal and Resistant Cultured Rat Hepatoma Cells
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