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John G. Kuhn
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Journal Articles

Characterization of the human cytochrome P450 (CYP450) isozymes involved in the metabolism of rebeccamycin analog (NSC 655649).

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Rajkumar Sevak, Pearl Delacruz, Irena Kosiba, John G. Kuhn
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 487.
Published: 01 April 2004
View articletitled, Characterization of the human cytochrome P450 (CYP450) isozymes involved in the metabolism of rebeccamycin analog (NSC 655649).
Journal Articles

The farnesyltransferase inhibitor Zarnestra suppresses protein farnesylation, not geranylgeranylation, in peripheral blood monocytes of patients with recurrent malignant glioma treated with Zarnestra in phase I/II clinical trials

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Said M. Sebti, Stephen Paquette, John G. Kuhn, Michael Prados, H. I. Robins, Lisa M. Deangelis, Susan M. Chang, David Schiff, Patrick Wen, W. K. Alfred Yung, Mark Gilbert, Karen Fink, Harry Greenberg, Larry Junck, Lauren E. Abrey, Frank S. Lieberman, Minesh P. Mehta, Jeffrey J. Raizer, Kenneth Hess, Timothy F. Cloughesy
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 920.
Published: 01 April 2004
View articletitled, The farnesyltransferase inhibitor Zarnestra suppresses protein farnesylation, not geranylgeranylation, in peripheral blood monocytes of patients with recurrent malignant glioma treated with Zarnestra in phase I/II clinical trials
Journal Articles

A Randomized Phase I Trial of Chronic Oral Etoposide with or without Granulocyte-Macrophage Colony-stimulating Factor in Patients with Advanced Malignancies

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Don W. Shaffer, Lon S. Smith, Howard A. Burris, Gary M. Clark, John R. Eckardt, Suzanne M. Fields, Geoffrey R. Weiss, David A. Rinaldi, Karen J. Bowen, John G. Kuhn, Daniel D. Von Hoff
Journal: Cancer Research
Cancer Res (1993) 53 (24): 5929–5933.
Published: 01 December 1993
View articletitled, A Randomized Phase I Trial of Chronic Oral Etoposide with or without Granulocyte-Macrophage Colony-stimulating Factor in Patients with Advanced Malignancies
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Journal Articles

A Phase I Clinical and Pharmacokinetic Trial of Hepsulfam

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Peter M. Ravdin, Kathy A. Havlin, Milton V. Marshall, Thomas D. Brown, James M. Koeller, John G. Kuhn, Gladys Rodriguez, Daniel D. Von Hoff
Journal: Cancer Research
Cancer Res (1991) 51 (23_Part_1): 6268–6272.
Published: 12 January 1991
View articletitled, A Phase I Clinical and Pharmacokinetic Trial of Hepsulfam
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Journal Articles

Phase I and Clinical Pharmacology Trial of 502U83 Using a Monthly Single Dose Schedule

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Daniel D. Von Hoff, John G. Kuhn, Kathleen A. Havlin, Anne-Marie Langevin, Thomas D. Brown, Geoffrey R. Weiss, Judy N. Turner, Joseph Purvis, V. Sol Lucas, Kenneth W. Bair, William Wargin, James Hubbell, Richard L. Tuttle, Jim M. Koeller, Gregory L. Freeman
Journal: Cancer Research
Cancer Res (1990) 50 (23): 7496–7500.
Published: 01 December 1990
View articletitled, Phase I and Clinical Pharmacology Trial of 502U83 Using a Monthly Single Dose Schedule
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Journal Articles

Phase I Clinical and Pharmacokinetic Trial of Brequinar Sodium (DUP 785; NSC 368390)

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Carlos L. Arteaga, Thomas D. Brown, John G. Kuhn, Huey-Shin L. Shen, Timothy J. O'Rourke, Kenneth Beougher, H. James Brentzel, Daniel D. Von Hoff, Geoffrey R. Weiss
Journal: Cancer Research
Cancer Res (1989) 49 (16): 4648–4653.
Published: 01 August 1989
View articletitled, Phase I Clinical and Pharmacokinetic Trial of Brequinar Sodium (DUP 785; NSC 368390)
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Journal Articles

Phase I and Clinical Pharmacology Trial of Crisnatol (BWA770U Mesylate) Using a Monthly Single-Dose Schedule

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Glenn S. Harman, John B. Craig, John G. Kuhn, J. Scott Luther, Judy N. Turner, Geoffrey R. Weiss, Dennis A. Tweedy, Jim Koeller, Richard L. Tuttle, V. Sol Lucas, William Wargin, John K. Whisnant, Daniel D. Von Hoff
Journal: Cancer Research
Cancer Res (1988) 48 (16): 4706–4710.
Published: 01 August 1988
View articletitled, Phase I and Clinical Pharmacology Trial of Crisnatol (BWA770U Mesylate) Using a Monthly Single-Dose Schedule
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Journal Articles

Phase I Study of α2-Interferon plus Doxorubicin in Patients with Solid Tumors

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Gisele A. Sarosy, Thomas D. Brown, Daniel D. Von Hoff, Robert J. Spiegel, James P. Golando, Kenneth L. Beougher, John G. Kuhn, Daniel L. Kisner
Journal: Cancer Research
Cancer Res (1986) 46 (10): 5368–5371.
Published: 01 October 1986
View articletitled, Phase I Study of α2-Interferon plus Doxorubicin in Patients with Solid Tumors
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Journal Articles

Phase I Clinical Investigation of 7-con-O-Methylnogaril, a New Anthracycline Antibiotic

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F. Andrew Dorr, Daniel D. Von Hoff, John G. Kuhn, Rowena Schwartz, Daniel L. Kisner
Journal: Cancer Research
Cancer Res (1986) 46 (5): 2562–2565.
Published: 01 May 1986
View articletitled, Phase I Clinical Investigation of 7-con-O-Methylnogaril, a New Anthracycline Antibiotic
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Journal Articles

Phase I Evaluation and Pharmacokinetics of Tiazofurin (2-β-d-Ribofuranosylthiazole-4-carboxamide, NSC 286193)1

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Teresa J. Melink, Daniel D. Von Hoff, John G. Kuhn, Marla R. Hersh, Lawrence A. Sternson, Thomas F. Patton, Robert Siegler, David H. Boldt, Gary M. Clark
Journal: Cancer Research
Cancer Res (1985) 45 (6): 2859–2865.
Published: 01 June 1985
View articletitled, Phase I Evaluation and Pharmacokinetics of Tiazofurin (2-β-d-Ribofuranosylthiazole-4-carboxamide, NSC 286193)1
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Journal Articles

Effects on Human Peripheral Lymphocytes of in Vivo Administration of 9-β-d-Arabinofuranosyl-2-fluoroadenine-5′-monophosphate (NSC 312887), a New Purine Antimetabolite1

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David H. Boldt, Daniel D. Von Hoff, John G. Kuhn, Marla Hersh
Journal: Cancer Research
Cancer Res (1984) 44 (10): 4661–4666.
Published: 01 October 1984
View articletitled, Effects on Human Peripheral Lymphocytes of in Vivo Administration of 9-β-d-Arabinofuranosyl-2-fluoroadenine-5′-monophosphate (NSC 312887), a New Purine Antimetabolite1
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