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John F. Smyth
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Journal Articles

A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment

Free
Hagen Kulbe, Probir Chakravarty, D. Andrew Leinster, Kellie A. Charles, Joseph Kwong, Richard G. Thompson, Jermaine I. Coward, Tiziana Schioppa, Stephen C. Robinson, William M. Gallagher, Laura Galletta, Michael A. Salako, John F. Smyth, Thorsten Hagemann, Donal J. Brennan, David D. Bowtell, Frances R. Balkwill
Journal: Cancer Research
Cancer Res (2012) 72 (1): 66–75.
https://doi.org/10.1158/0008-5472.CAN-11-2178
Published: 02 January 2012
View article titled, A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
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Includes: Supplementary data
Journal Articles

WWOX Gene Expression Abolishes Ovarian Cancer Tumorigenicity In vivo and Decreases Attachment to Fibronectin via Integrin α3

Free
Charlie Gourley, Adam J.W. Paige, Karen J. Taylor, Carol Ward, Barbara Kuske, Jieqing Zhang, Mingjun Sun, Szymon Janczar, David J. Harrison, Morwenna Muir, John F. Smyth, Hani Gabra
Journal: Cancer Research
Cancer Res (2009) 69 (11): 4835–4842.
https://doi.org/10.1158/0008-5472.CAN-08-2974
Published: 01 June 2009
View article titled, WWOX Gene Expression Abolishes Ovarian Cancer Tumorigenicity In vivo and Decreases Attachment to Fibronectin via Integrin α3
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Includes: Supplementary data
Journal Articles

Identification of estrogen-regulated biomarkers in ovarian cancer patients treated with letrozole

Free
Graeme Walker, Simon P. Langdon, Kenneth Macleod, Alistair Williams, John F. Smyth
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 548–549.
Published: 15 April 2006
View article titled, Identification of estrogen-regulated biomarkers in ovarian cancer patients treated with letrozole
Journal Articles

The function of tumor suppressor genes in ovarian cancer: the role of LSAMP

Free
Melanie Spears, Genevieve J. Rabiasz, Diane Scott, Evangelos Ntougkos, Scott Fegan, Eric P. Miller, John F. Smyth, Grant C. Sellar
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 587.
Published: 15 April 2006
View article titled, The function of tumor suppressor genes in ovarian cancer: the role of LSAMP
Journal Articles

Altered ErbB Receptor Signaling and Gene Expression in Cisplatin-Resistant Ovarian Cancer

Free
Kenneth Macleod, Peter Mullen, Jane Sewell, Genevieve Rabiasz, Sandra Lawrie, Eric Miller, John F. Smyth, Simon P. Langdon
Journal: Cancer Research
Cancer Res (2005) 65 (15): 6789–6800.
https://doi.org/10.1158/0008-5472.CAN-04-2684
Published: 01 August 2005
View article titled, Altered ErbB Receptor Signaling and Gene Expression in Cisplatin-Resistant Ovarian Cancer
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Journal Articles

Microarray analysis of OPCML tumor suppressor function in SKOV-3 ovarian cancer cells

Free
Genevieve J. Rabiasz, Diane Scott, Eric P. Miller, Euan A. Stronach, Karen J. Taylor, Evangelos Ntougkos, Hani Gabra, John F. Smyth, Grant C. Sellar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 639–640.
Published: 01 May 2005
View article titled, Microarray analysis of OPCML tumor suppressor function in SKOV-3 ovarian cancer cells
Journal Articles

The IgLON family in epithelial ovarian cancer: an expression study

Free
Evangelos Ntougkos, Robert Rush, Diane Scott, Hani Gabra, John F. Smyth, Grant C. Sellar
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 639.
Published: 01 May 2005
View article titled, The IgLON family in epithelial ovarian cancer: an expression study
Journal Articles

Biological activity of infliximab, an anti-TNF-α monoclonal antibody, in the tumor microenvironment of advanced epithelial ovarian patients

Free
Kellie A. Charles, Susan A. Hoare, Thorsten Hagermann, Diane X. Scott, Rona Aird, John F. Smyth, Frances R. Balkwill
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 166.
Published: 01 May 2005
View article titled, Biological activity of infliximab, an anti-TNF-α monoclonal antibody, in the tumor microenvironment of advanced epithelial ovarian patients
Journal Articles

Kahalalide F appears to promote necrotic cell death in hepatoma cell lines

Free
Jane M. Sewell, Simon P. Langdon, John F. Smyth, Duncan I. Jodrell, Sylvie Guichard
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 347–348.
Published: 01 April 2004
View article titled, Kahalalide F appears to promote necrotic cell death in hepatoma cell lines
Journal Articles

Reconstituted WWOX expression in PEO1 ovarian cancer cells results in abolition of tumorigenicity in nude mice and decreased migration towards matrix components

Free
Charlie Gourley, Adam J. Paige, Karen J. Taylor, Diane Scott, Hani Gabra, John F. Smyth
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 412–413.
Published: 01 April 2004
View article titled, Reconstituted WWOX expression in PEO1 ovarian cancer cells results in abolition of tumorigenicity in nude mice and decreased migration towards matrix components
Journal Articles

Identification of Clinically Relevant Genes on Chromosome 11 in a Functional Model of Ovarian Cancer Tumor Suppression

Free
Euan A. Stronach, Grant C. Sellar, Cherie Blenkiron, Genevieve J. Rabiasz, Karen J. Taylor, Eric P. Miller, Charles E. Massie, Awatif Al-Nafussi, John F. Smyth, David J. Porteous, Hani Gabra
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8648–8655.
Published: 24 December 2003
View article titled, Identification of Clinically Relevant Genes on Chromosome 11 in a Functional Model of Ovarian Cancer Tumor Suppression
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Journal Articles

Glucuronidation as a Mechanism of Intrinsic Drug Resistance in Human Colon Cancer: Reversal of Resistance by Food Additives

Free
Jeffrey Cummings, Brian T. Ethell, Lesley Jardine, Gary Boyd, Janet S. Macpherson, Brian Burchell, John F. Smyth, Duncan I. Jodrell
Journal: Cancer Research
Cancer Res (2003) 63 (23): 8443–8450.
Published: 16 December 2003
View article titled, Glucuronidation as a Mechanism of Intrinsic Drug Resistance in Human Colon Cancer: Reversal of Resistance by Food Additives
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Journal Articles

BARX2 Induces Cadherin 6 Expression and Is a Functional Suppressor of Ovarian Cancer Progression

Free
Grant C. Sellar, Li Li, Karen P. Watt, Barry D. Nelkin, Genevieve J. Rabiasz, Euan A. Stronach, Eric P. Miller, David J. Porteous, John F. Smyth, Hani Gabra
Journal: Cancer Research
Cancer Res (2001) 61 (19): 6977–6981.
Published: 01 October 2001
View article titled, BARX2 Induces Cadherin 6 Expression and Is a Functional Suppressor of Ovarian Cancer Progression
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Journal Articles

Expression of erbB-4/HER-4 Growth Factor Receptor Isoforms in Ovarian Cancer

Free
Lynn M. R. Gilmour, Kenneth G. Macleod, Alison McCaig, William J. Gullick, John F. Smyth, Simon P. Langdon
Journal: Cancer Research
Cancer Res (2001) 61 (5): 2169–2176.
Published: 01 March 2001
View article titled, Expression of erbB-4/HER-4 Growth Factor Receptor Isoforms in Ovarian Cancer
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Journal Articles

A 700-kb Physical Map of a Region of 16q23.2 Homozygously Deleted in Multiple Cancers and Spanning the Common Fragile Site FRA16D

Free
Adam J. W. Paige, Karen J. Taylor, Aengus Stewart, John G. Sgouros, Hani Gabra, Grant C. Sellar, John F. Smyth, David J. Porteous, J. E. Vivienne Watson
Journal: Cancer Research
Cancer Res (2000) 60 (6): 1690–1697.
Published: 01 March 2000
View article titled, A 700-kb Physical Map of a Region of 16q23.2 Homozygously Deleted in Multiple Cancers and Spanning the Common Fragile Site FRA16D
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Journal Articles

Identification of a Region of Frequent Loss of Heterozygosity at 11q24 in Colorectal Cancer

Free
Kate C. Connolly, Hani Gabra, Christopher J. Millwater, Karen J. Taylor, Genevieve J. Rabiasz, J. E. Vivienne Watson, John F. Smyth, Andrew H. Wyllie, Duncan I. Jodrell
Journal: Cancer Research
Cancer Res (1999) 59 (12): 2806–2809.
Published: 15 June 1999
View article titled, Identification of a Region of Frequent Loss of Heterozygosity at 11q24 in Colorectal Cancer
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Journal Articles

Definition and Refinement of a Region of Loss of Heterozygosity at 11q23.3–q24.3 in Epithelial Ovarian Cancer Associated with Poor Prognosis

Free
Hani Gabra, J. E. Vivienne Watson, Karen J. Taylor, James Mackay, Robert C. F. Leonard, C. Michael Steel, David J. Porteous, John F. Smyth
Journal: Cancer Research
Cancer Res (1996) 56 (5): 950–954.
Published: 01 March 1996
View article titled, Definition and Refinement of a Region of Loss of Heterozygosity at 11q23.3–q24.3 in Epithelial Ovarian Cancer Associated with Poor Prognosis
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Journal Articles

Characterization of the Major Metabolites of Flavone Acetic Acid and Comparison of Their Disposition in Humans and Mice

Free
Jeffrey Cummings, John A. Double, Michael C. Bibby, Peter Farmer, Susan Evans, David J. Kerr, Stanley B. Kaye, John F. Smyth
Journal: Cancer Research
Cancer Res (1989) 49 (13): 3587–3593.
Published: 01 July 1989
View article titled, Characterization of the Major Metabolites of Flavone Acetic Acid and Comparison of Their Disposition in Humans and Mice
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Journal Articles

Characterization and Properties of Nine Human Ovarian Adenocarcinoma Cell Lines

Free
Simon P. Langdon, Sandra S. Lawrie, Frances G. Hay, Mary M. Hawkes, Amanda McDonald, Ian P. Hayward, Dick J. Schol, Jo Hilgers, Robert C. F. Leonard, John F. Smyth
Journal: Cancer Research
Cancer Res (1988) 48 (21): 6166–6172.
Published: 01 November 1988
View article titled, Characterization and Properties of Nine Human Ovarian Adenocarcinoma Cell Lines
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Journal Articles

Effect of Sodium Butyrate and Other Differentiation Inducers on Poorly Differentiated Human Ovarian Adenocarcinoma Cell Lines

Free
Simon P. Langdon, Mary M. Hawkes, Frances G. Hay, Sandra S. Lawrie, Dick J. Schol, Jo Hilgers, Robert C. F. Leonard, John F. Smyth
Journal: Cancer Research
Cancer Res (1988) 48 (21): 6161–6165.
Published: 01 November 1988
View article titled, Effect of Sodium Butyrate and Other Differentiation Inducers on Poorly Differentiated Human Ovarian Adenocarcinoma Cell Lines
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