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Abstract 138: Lysyl oxidases suppress pancreatic cancer progression by inhibiting focal adhesion kinase signaling

Lijuan Sun, Jean Albrengues, John E. Wilkinson, Sarah L. Dallas, Valerie M. Weaver, Mikala Egeblad, Mario A. Shields

Cancer Res (2025) 85 (8_Supplement_1): 138.

https://doi.org/10.1158/1538-7445.AM2025-138

Published: 21 April 2025

View articletitled, Abstract 138: Lysyl oxidases suppress pancreatic cancer progression by inhibiting focal adhesion kinase signaling

Journal Articles

Abstract A079: Loss of BPTF restores estrogen-regulated programs and suppress metastatic development of mammary tumors

Chen Chen, Michael F. Ciccone, Marygrace c. Trousdell, Deeptiman Chatterjee, Yixin Zhao, Steven M. Lewis, Dhivya Anandan, John E. Wilkinson, William C. K. Pomerantz, Adam Siepel, Camila O. dos Santos

Cancer Res (2024) 84 (3_Supplement_1): A079.

https://doi.org/10.1158/1538-7445.ADVBC23-A079

Published: 01 February 2024

View articletitled, Abstract A079: Loss of BPTF restores estrogen-regulated programs and suppress metastatic development of mammary tumors

Journal Articles

Abstract C093: Dysregulated spliceosomal components promote pancreatic cancer progression

Ledong Wan, Kuan-Ting Lin, Mohammad A. Rahman, Yuma Ishigami, Alexander J. Kral, Dillon Voss, Zhikai Wang, Mads A. Jensen, John E. Wilkinson, Youngkyu Park, David A. Tuveson, Adrian R. Krainer

Cancer Res (2024) 84 (2_Supplement): C093.

https://doi.org/10.1158/1538-7445.PANCA2023-C093

Published: 16 January 2024

View articletitled, Abstract C093: Dysregulated spliceosomal components promote pancreatic cancer progression

Journal Articles

Abstract A014: Identifying and overcoming resistance to RAS targeted therapy in colorectal cancer

Marie J. Parsons, Maria Zafra, Sukanya Goswami, Maria Teresa Calvo Fernandez, John E. Wilkinson, Lukas E. Dow

Cancer Res (2022) 82 (23_Supplement_1): A014.

https://doi.org/10.1158/1538-7445.CRC22-A014

Published: 01 December 2022

View articletitled, Abstract A014: Identifying and overcoming resistance to RAS targeted therapy in colorectal cancer

Journal Articles

Abstract PR009: An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas

David J. Falvo, Adrien Grimont, Paul Zumbo, Julie L. Yang, Alexa Osterhoudt, Grace Pan, Andre F. Rendeiro, John E. Wilkinson, Friederike Dündar, Olivier Elemento, Rhonda K. Yantiss, Doron Betel, Richard Koch, Rohit Chandwani

Cancer Res (2022) 82 (22_Supplement): PR009.

https://doi.org/10.1158/1538-7445.PANCA22-PR009

Published: 15 November 2022

View articletitled, Abstract PR009: An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas

Journal Articles

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Sonam Bhatia, Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy, Peter Andrews, Cheng Fan, Charles M. Perou, Jonathan Preall, Taehoon Ha, Dennis Plenker, David A. Tuveson, Arvind Rishi, John E. Wilkinson, W. Richard McCombie, Karen Kostroff, David L. Spector

Cancer Res (2022) 82 (7): 1174–1192.

https://doi.org/10.1158/0008-5472.CAN-21-2807

Published: 01 April 2022

View articletitled, Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

Includes: Supplementary data

Journal Articles

ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth

Wai Kit Ma, Dillon M. Voss, Juergen Scharner, Ana S.H. Costa, Kuan-Ting Lin, Hyun Yong Jeon, John E. Wilkinson, Michaela Jackson, Frank Rigo, C. Frank Bennett, Adrian R. Krainer

Cancer Res (2022) 82 (5): 900–915.

https://doi.org/10.1158/0008-5472.CAN-20-0948

Published: 03 March 2022

View articletitled, ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth

Includes: Supplementary data

Journal Articles

BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas

Matthew L. Fisher, Seamus Balinth, Yon Hwangbo, Caizhi Wu, Carlos Ballon, John E. Wilkinson, Gary L. Goldberg, Alea A. Mills

Cancer Res (2021) 81 (24): 6246–6258.

https://doi.org/10.1158/0008-5472.CAN-21-0707

Published: 15 December 2021

View articletitled, BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas

Includes: Supplementary data

Journal Articles

Abstract A09: Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant mammary lesions in response to cMYC-overexpression

Mary J. Feigman, Matthew A. Moss, Chen Chen, Samantha L. Cyrill, Michael Ciccone, Marygrace Trousdell, Shih Ting Yang, Wesley D. Frey, John E. Wilkinson, Camila O. dos Santos

Cancer Res (2020) 80 (11_Supplement): A09.

https://doi.org/10.1158/1538-7445.CAMODELS2020-A09

Published: 02 June 2020

View articletitled, Abstract A09: Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant mammary lesions in response to cMYC-overexpression

Journal Articles

Abstract PR06: An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants

Maria Paz Zafra, Direna Alonso-Curbelo, Sukanya Goswami, Emma M Schatoff, Teng Han, John E. Wilkinson, Lukas E. Dow

Cancer Res (2020) 80 (11_Supplement): PR06.

https://doi.org/10.1158/1538-7445.CAMODELS2020-PR06

Published: 02 June 2020

View articletitled, Abstract PR06: An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants

Journal Articles

Abstract PR01: Senescence induction triggers vascular remodeling and new vulnerabilities to chemo- and immunotherapy in pancreas cancer

Cancer Res (2019) 79 (24_Supplement): PR01.

https://doi.org/10.1158/1538-7445.PANCA19-PR01

Published: 13 December 2019

View articletitled, Abstract PR01: Senescence induction triggers vascular remodeling and new vulnerabilities to chemo- and immunotherapy in pancreas cancer

Journal Articles

ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms

Phillip L. Palmbos, Lidong Wang, Huibin Yang, Yin Wang, Jacob Leflein, McKenzie L. Ahmet, John E. Wilkinson, Chandan Kumar-Sinha, Gina M. Ney, Scott A. Tomlins, Stephanie Daignault, Lakshmi. P. Kunju, Xue-Ru Wu, Yair Lotan, Monica Liebert, Mats E. Ljungman, Diane M. Simeone

Cancer Res (2015) 75 (23): 5155–5166.

https://doi.org/10.1158/0008-5472.CAN-15-0603

Published: 30 November 2015

View articletitled, ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms

Includes: Supplementary data

Journal Articles

Abstract 2258: Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2

Dawid G. Nowak, Hyejin Cho, Tali Herzka, Victoria M.Y. Wang, Serif Senturk, Daniel V. DeMarco, David Ding, Christof Fellmann, Tumas Beinortas, David Kleinman, Kaitlin Watrud, Muhan Chen, John E. Wilkinson, Mireia Castillo-Martin, Carlos Cordon-Cardo, Brian D. Robinson, Lloyd C. Trotman

Cancer Res (2015) 75 (15_Supplement): 2258.

https://doi.org/10.1158/1538-7445.AM2015-2258

Published: 01 August 2015

View articletitled, Abstract 2258: Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2

Journal Articles

Abstract LB-40: Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition

Jessica Bolden, Nilgun Tasdemir, Lukas Dow, Johan H. van Es, John E. Wilkinson, Zhen Zhao, Hans Clevers, Scott W. Lowe

Cancer Res (2014) 74 (19_Supplement): LB-40.

https://doi.org/10.1158/1538-7445.AM2014-LB-40

Published: 01 October 2014

View articletitled, Abstract LB-40: Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition

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Abstract 138: Lysyl oxidases suppress pancreatic cancer progression by inhibiting focal adhesion kinase signaling

Abstract A079: Loss of BPTF restores estrogen-regulated programs and suppress metastatic development of mammary tumors

Abstract C093: Dysregulated spliceosomal components promote pancreatic cancer progression

Abstract A014: Identifying and overcoming resistance to RAS targeted therapy in colorectal cancer

Abstract PR009: An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas

Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics

ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth

BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas

Abstract A09: Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant mammary lesions in response to cMYC-overexpression

Abstract PR06: An in vivo KRAS allelic series reveals distinct phenotypes of common oncogenic variants

Abstract PR01: Senescence induction triggers vascular remodeling and new vulnerabilities to chemo- and immunotherapy in pancreas cancer

ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms

Abstract 2258: Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2

Abstract LB-40: Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition

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