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John E. Shively
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Journal Articles

Abstract 7374: Mathematical modeling of targeted radionuclide therapy and CAR-T cell immunotherapy for maximizing therapeutic efficacy in multiple myeloma

Vikram Adhikarla, Dennis Awuah, Enrico Caserta, Megan Minnix, Maxim Kuznetsov, Amrita Krishnan, Jeffrey Y. Wong, John E. Shively, Xiuli Wang, Flavia Pichiorri, Russell C. Rockne
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7374.
https://doi.org/10.1158/1538-7445.AM2024-7374
Published: 22 March 2024
View article titled, Abstract 7374: Mathematical modeling of targeted radionuclide therapy and CAR-T cell immunotherapy for maximizing therapeutic efficacy in multiple myeloma
Journal Articles

Abstract 2732: A mathematical model for optimization of combination therapy involving targeted radionuclide and CAR-T cell therapy

Vikram Adhikarla, Dennis Awuah, Alexander B. Brummer, Enrico Caserta, Amrita Krishnan, Flavia Pichiorri, Megan M. Minnix, John E. Shively, Jeffrey Y.C. Wong, Xiuli Wang, Russell C. Rockne
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2732.
https://doi.org/10.1158/1538-7445.AM2022-2732
Published: 15 June 2022
View article titled, Abstract 2732: A mathematical model for optimization of combination therapy involving targeted radionuclide and CAR-T cell therapy
Journal Articles

Tumor Angiogenesis Mediated by Myeloid Cells Is Negatively Regulated by CEACAM1

Rongze Lu, Maciej Kujawski, Hao Pan, John E. Shively
Journal: Cancer Research
Cancer Res (2012) 72 (9): 2239–2250.
https://doi.org/10.1158/0008-5472.CAN-11-3016
Published: 30 April 2012
View article titled, Tumor Angiogenesis Mediated by Myeloid Cells Is Negatively Regulated by CEACAM1
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Includes: Supplementary data
Journal Articles

Abstract LB-499: Malignancy-sustaining characteristics of cancer-associated plasma: role of systemic cytokines in maintaining tumor latency

Julia Kirshner, Kyle Beamis, Zhifang Zhang, Mary Zheng, Linda M. Pilarski, John E. Shively
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-499.
https://doi.org/10.1158/1538-7445.AM2012-LB-499
Published: 15 April 2012
View article titled, Abstract LB-499: Malignancy-sustaining characteristics of cancer-associated plasma: role of systemic cytokines in maintaining tumor latency
Journal Articles

Abstract 5234: CEACAM1 expressing spheroid with a hollow beyond the invasive margin indicates the malignant potential of colorectal cancer

Shozo Yokoyama, Koichi Tamura, Junji Ieda, Katsunari Takifuji, Tsukasa Hotta, Kenji Matsuda, Yoshimasa Oku, Toru Nasu, Shigehisa Kiriyama, Naoyuki Yamamoto, John E. Shively, Hiroki Yamaue
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5234.
https://doi.org/10.1158/1538-7445.AM2011-5234
Published: 15 April 2011
View article titled, Abstract 5234: CEACAM1 expressing spheroid with a hollow beyond the invasive margin indicates the malignant potential of colorectal cancer
Journal Articles

Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy

Vania Kenanova, Tove Olafsen, Lawrence E. Williams, Nora H. Ruel, Jeffrey Longmate, Paul J. Yazaki, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2007) 67 (2): 718–726.
https://doi.org/10.1158/0008-5472.CAN-06-0454
Published: 18 January 2007
View article titled, Radioiodinated versus Radiometal-Labeled Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments: Optimal Pharmacokinetics for Therapy
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Journal Articles

Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays

Chunxia Li, Mitsuo Kato, Lily Shiue, John E. Shively, Manuel Ares, Jr., Ren-Jang Lin
Journal: Cancer Research
Cancer Res (2006) 66 (4): 1990–1999.
https://doi.org/10.1158/0008-5472.CAN-05-2593
Published: 17 February 2006
View article titled, Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays
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Includes: Supplementary data
Journal Articles

The Role of Peroxiredoxin II in Radiation-Resistant MCF-7 Breast Cancer Cells

Tieli Wang, Daniel Tamae, Thomas LeBon, John E. Shively, Yun Yen, Jian Jian Li
Journal: Cancer Research
Cancer Res (2005) 65 (22): 10338–10346.
https://doi.org/10.1158/0008-5472.CAN-04-4614
Published: 15 November 2005
View article titled, The Role of Peroxiredoxin II in Radiation-Resistant MCF-7 Breast Cancer Cells
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Journal Articles

Optimizing Radiolabeled Engineered Anti-p185HER2 Antibody Fragments for In vivo Imaging

Tove Olafsen, Vania E. Kenanova, Gobalakrishnan Sundaresan, Anne-Line Anderson, Desiree Crow, Paul J. Yazaki, Lin Li, Michael F. Press, Sanjiv S. Gambhir, Lawrence E. Williams, Jeffrey Y.C. Wong, Andrew A. Raubitschek, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5907–5916.
https://doi.org/10.1158/0008-5472.CAN-04-4472
Published: 01 July 2005
View article titled, Optimizing Radiolabeled Engineered Anti-p185<sup>HER2</sup> Antibody Fragments for <em>In vivo</em> Imaging
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Includes: Supplementary data
Journal Articles

Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties

Vania E. Kenanova, Tove Olafsen, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Lawrence E. Williams, John E. Shively, David Colcher, Sanjiv S. Gambhir, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1243.
Published: 01 May 2005
View article titled, Engineered anti-CEA scFv-Fc antibody fragments tailored for pharmacokinetic and imaging properties
Journal Articles

MicroPET imaging of breast cancer xenografts with anti-p185HER2 minibody and scFv-Fc antibody fragments

Tove Olafsen, Vania E. Kenanova, Gobalakrishnan Sundaresan, Anne-Line Anderson, Michael F. Press, Sanjiv S. Gambhir, Lawrence E. Williams, Andrew A. Raubitschek, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 899–900.
Published: 01 May 2005
View article titled, MicroPET imaging of breast cancer xenografts with anti-p185<sup>HER2</sup> minibody and scFv-Fc antibody fragments
Journal Articles

Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments

Vania Kenanova, Tove Olafsen, Desiree M. Crow, Gobalakrishnan Sundaresan, Murugesan Subbarayan, Nora H. Carter, David N. Ikle, Paul J. Yazaki, Arion F. Chatziioannou, Sanjiv S. Gambhir, Lawrence E. Williams, John E. Shively, David Colcher, Andrew A. Raubitschek, Anna M. Wu
Journal: Cancer Research
Cancer Res (2005) 65 (2): 622–631.
https://doi.org/10.1158/0008-5472.622.65.2
Published: 03 February 2005
View article titled, Tailoring the Pharmacokinetics and Positron Emission Tomography Imaging Properties of Anti–Carcinoembryonic Antigen Single-Chain Fv-Fc Antibody Fragments
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Journal Articles

Targeting and Therapy of Carcinoembryonic Antigen-expressing Tumors in Transgenic Mice with an Antibody-Interleukin 2 Fusion Protein

Xiaochuan Xu, Patrick Clarke, György Szalai, John E. Shively, Lawrence E. Williams, Yu Shyr, Ergang Shi, F. James Primus
Journal: Cancer Research
Cancer Res (2000) 60 (16): 4475–4484.
Published: 01 August 2000
View article titled, Targeting and Therapy of Carcinoembryonic Antigen-expressing Tumors in Transgenic Mice with an Antibody-Interleukin 2 Fusion Protein
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Journal Articles

Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-CH3) Which Exhibits Rapid, High-Level Targeting of Xenografts

Shi-zhen Hu, Louise Shively, Andrew Raubitschek, Mark Sherman, Lawrence E. Williams, Jeffrey Y. C. Wong, John E. Shively, Anna M. Wu
Journal: Cancer Research
Cancer Res (1996) 56 (13): 3055–3061.
Published: 01 July 1996
View article titled, Minibody: A Novel Engineered Anti-Carcinoembryonic Antigen Antibody Fragment (Single-Chain Fv-C<sub>H</sub>3) Which Exhibits Rapid, High-Level Targeting of Xenografts
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Journal Articles

Initial Experience Evaluating 90Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial

Jeffrey Y. C. Wong, Lawrence E. Williams, David M. Yamauchi, Tamara Odom-Maryon, Jose M. Esteban, Michael Neumaier, Anna M. Wu, David K. Johnson, F. James Primus, John E. Shively, Andrew A. Raubitschek
Journal: Cancer Research
Cancer Res (1995) 55 (23_Supplement): 5929s–5934s.
Published: 01 December 1995
View article titled, Initial Experience Evaluating <sup>90</sup>Yttrium-Radiolabeled Anti-Carcinoembryonic Antigen Chimeric T84.66 in a Phase I Radioimmunotherapy Trial
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Journal Articles

In Vitro and in Vivo Footprint Analysis of the Promoter of Carcinoembryonic Antigen in Colon Carcinoma Cells: Effects of Interferon γ Treatment

Charng-Jui Chen, Li-Jing Li, Aiko Maruya, John E. Shively
Journal: Cancer Research
Cancer Res (1995) 55 (17): 3873–3882.
Published: 01 September 1995
View article titled, <em>In Vitro</em> and <em>in Vivo</em> Footprint Analysis of the Promoter of Carcinoembryonic Antigen in Colon Carcinoma Cells: Effects of Interferon γ Treatment
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Journal Articles

Differential Regulation of Carcinoembryonic Antigen and Biliary Glycoprotein by γ-Interferon

Hiroki Takahashi, Yasuji Okai, Raymond J. Paxton, Laura J. F. Hefta, John E. Shively
Journal: Cancer Research
Cancer Res (1993) 53 (7): 1612–1619.
Published: 01 April 1993
View article titled, Differential Regulation of Carcinoembryonic Antigen and Biliary Glycoprotein by γ-Interferon
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Journal Articles

Expression of Carcinoembryonic Antigen and Its Predicted Immunoglobulin-like Domains in HeLa Cells for Epitope Analysis

Laura J. F. Hefta, Fun-Shan Chen, Michael Ronk, Sybille L. Sauter, Virender Sarin, Shinzo Oikawa, Hiroshi Nakazato, Stanley Hefta, John E. Shively
Journal: Cancer Research
Cancer Res (1992) 52 (20): 5647–5655.
Published: 01 October 1992
View article titled, Expression of Carcinoembryonic Antigen and Its Predicted Immunoglobulin-like Domains in HeLa Cells for Epitope Analysis
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Journal Articles

Identification and Characterization of New Antigenic Fragments Related to Carcinoembryonic Antigen in Adult Feces

Jerry G. Henslee, Edward J. Vachula, Raymond J. Paxton, Matthew S. Matias, John E. Shively, Harry G. Rittenhouse, Joseph T. Tomita
Journal: Cancer Research
Cancer Res (1992) 52 (15): 4175–4182.
Published: 01 August 1992
View article titled, Identification and Characterization of New Antigenic Fragments Related to Carcinoembryonic Antigen in Adult Feces
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Journal Articles

Carcinoembryonic Antigen Expression of Resurgent Human Colon Carcinoma after Treatment with Therapeutic Doses of 90Y-α-Carcinoembryonic Antigen Monoclonal Antibody

Jose M. Esteban, Joseph A. Kuhn, Barbara Felder, Jeffrey Y. C. Wong, Hector Battifora, J. David Beatty, Philip M. Wanek, John E. Shively
Journal: Cancer Research
Cancer Res (1991) 51 (14): 3802–3806.
Published: 01 July 1991
View article titled, Carcinoembryonic Antigen Expression of Resurgent Human Colon Carcinoma after Treatment with Therapeutic Doses of <sup>90</sup>Y-α-Carcinoembryonic Antigen Monoclonal Antibody
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