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John Blenis
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Journal Articles

Decoding Serine Metabolism: Unveiling Novel Pathways for Evolving Cancer Therapies

Aristotle Lau, John Blenis, Guillermo Burgos-Barragan
Journal: Cancer Research
Cancer Res (2024) 84 (8): 1191–1194.
https://doi.org/10.1158/0008-5472.CAN-24-0541
Published: 15 April 2024
View article titled, Decoding Serine Metabolism: Unveiling Novel Pathways for Evolving Cancer Therapies
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Journal Articles

Abstract 2378: Methylmalonic acid is elevated in non-small cell lung cancer and promotes drug resistance

Bobak Parang, Zhongchi Li, Vivien Low, Jennifer Endress, Murtaza Malbari, Ashish Saxena, Nasser Altorki, John Blenis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2378.
https://doi.org/10.1158/1538-7445.AM2022-2378
Published: 15 June 2022
View article titled, Abstract 2378: Methylmalonic acid is elevated in non-small cell lung cancer and promotes drug resistance
Journal Articles

Abstract 3175: Methylmalonic acid in TME signaling

Vivien Low, Zhongchi Li, Ashley Laughney, Wenbing Jin, Noah Dephoure, Valbona Luga, Ethan Earlie, Bobak Parang, Chunjun Guo, Lewis Cantley, John Blenis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3175.
https://doi.org/10.1158/1538-7445.AM2022-3175
Published: 15 June 2022
View article titled, Abstract 3175: Methylmalonic acid in TME signaling
Journal Articles

Abstract 162: Identification of novel targets of Serine/arginine-rich protein-specific kinase 2

Kripa Shobana Ganesh, Bethany Schaffer, Gina Lee, Jared Johnson, Tomer M. Yaron, Noah Dephoure, Lewis C. Cantley, John Blenis
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 162.
https://doi.org/10.1158/1538-7445.AM2022-162
Published: 15 June 2022
View article titled, Abstract 162: Identification of novel targets of Serine/arginine-rich protein-specific kinase 2
Journal Articles

Abstract IA03: mTORC1/S6K1: Regulation of RNA biogenesis, protein synthesis, and cell metabolism

John Blenis, Gina Lee, Jamie Dempsey, Christina England
Journal: Cancer Research
Cancer Res (2017) 77 (6_Supplement): IA03.
https://doi.org/10.1158/1538-7445.Transcontrol16-IA03
Published: 14 March 2017
View article titled, Abstract IA03: mTORC1/S6K1: Regulation of RNA biogenesis, protein synthesis, and cell metabolism
Journal Articles

mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress

Jing Li, Sejeong Shin, Yang Sun, Sang-Oh Yoon, Chenggang Li, Erik Zhang, Jane Yu, Jianming Zhang, John Blenis
Journal: Cancer Research
Cancer Res (2016) 76 (16): 4816–4827.
https://doi.org/10.1158/0008-5472.CAN-15-2629
Published: 14 August 2016
View article titled, mTORC1-Driven Tumor Cells Are Highly Sensitive to Therapeutic Targeting by Antagonists of Oxidative Stress
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Includes: Supplementary data
Journal Articles

Abstract C59: Estradiol and mTORC2 orchestrate to enhance prostaglandin biosynthesis andtumorigenesis in tuberous sclerosis complex

Chenggang Li, Po-Shun Lee, Xiaoxiao Gu, Yang Sun, Erik Zhang, Alfredo Csibi, Jing Li, Carmen Priolo, Yanan Guo, Chin-Lee Wu, John Blenis, Kai-Feng Xu, Elizabeth Petri Henske, Bruce Levy, David Kwiatkowski, Jane J. Yu
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C59.
https://doi.org/10.1158/1538-7445.FBCR13-C59
Published: 15 May 2014
View article titled, Abstract C59: Estradiol and mTORC2 orchestrate to enhance prostaglandin biosynthesis andtumorigenesis in tuberous sclerosis complex
Journal Articles

Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism

Sarah-Maria Fendt, Eric L. Bell, Mark A. Keibler, Shawn M. Davidson, Gregory J. Wirth, Brian Fiske, Jared R. Mayers, Matthias Schwab, Gary Bellinger, Alfredo Csibi, Akash Patnaik, Marie Jose Blouin, Lewis C. Cantley, Leonard Guarente, John Blenis, Michael N. Pollak, Aria F. Olumi, Matthew G. Vander Heiden, Gregory Stephanopoulos
Journal: Cancer Research
Cancer Res (2013) 73 (14): 4429–4438.
https://doi.org/10.1158/0008-5472.CAN-13-0080
Published: 15 July 2013
View article titled, Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism
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Includes: Supplementary data
Journal Articles

Abstract SY29-01: mTOR, metabolism, and cell growth control

John Blenis, Alfredo Csibi, Sang Gyun Kim, Andrew Choo, Gwen Buel, Young Jin Jang, Gregory Hoffman
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): SY29-01.
https://doi.org/10.1158/1538-7445.AM2012-SY29-01
Published: 15 April 2012
View article titled, Abstract SY29-01: mTOR, metabolism, and cell growth control
Journal Articles

Abstract SY09-01: Control of class III PI 3-kinase in autophagy and cancers

Marta Lipinski, Tsuyoshi Furuya, Minsu Kim, Greg Hoffman, Aylwin Ng, John Blenis, Ramnik Xavior, Junying Yuan
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): SY09-01.
https://doi.org/10.1158/1538-7445.AM2011-SY09-01
Published: 15 April 2011
View article titled, Abstract SY09-01: Control of class III PI 3-kinase in autophagy and cancers
Journal Articles

Abstract #2853: Genes associated with tumor invasion in a genetically engineered mesothelioma model

Melissa Merritt, Michelle Mendoza, John Blenis, Tan Ince
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2853.
Published: 01 May 2009
View article titled, Abstract #2853: Genes associated with tumor invasion in a genetically engineered mesothelioma model
Journal Articles

Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor-β

Rod A. Rahimi, Mahefatiana Andrianifahanana, Mark C. Wilkes, Maryanne Edens, Theodore J. Kottom, John Blenis, Edward B. Leof
Journal: Cancer Research
Cancer Res (2009) 69 (1): 84–93.
https://doi.org/10.1158/0008-5472.CAN-08-2146
Published: 31 December 2008
View article titled, Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor-β
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