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John A. Glaspy
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Journal Articles

Abstract 7551: Combined epigenetic therapy and immune checkpoint blockade drive reshaping of the tumor microenvironment of platinum resistant ovarian cancer

Blair V. Landon, Guneet Kaleka, Archana Balan, Julia L. Boland, Christopher Cherry, Gavin Pereira, Cynthia Zahnow, Boris Winterhoff, Stephen Baylin, Victor E. Velculescu, Gottfried E. Konecny, John A. Glaspy, Valsamo Anagnostou
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 7551.
https://doi.org/10.1158/1538-7445.AM2024-7551
Published: 22 March 2024
View article titled, Abstract 7551: Combined epigenetic therapy and immune checkpoint blockade drive reshaping of the tumor microenvironment of platinum resistant ovarian cancer
Journal Articles

Abstract 1900: TORL-3-600, a novel antibody drug conjugate directed against cadherin 17 (CDH17), has preclinical efficacy in colorectal, gastric, and pancreatic cancer

Neil A. O'Brien, Martina SJ McDermott, Jun Zhang, Ming Lu, Ke Wei Gong, Benjamin Hoffstrom, Wei Ping Jia, Tong Luo, Athena M. Madrid, Min Liang, John A. Glaspy, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1900.
https://doi.org/10.1158/1538-7445.AM2024-1900
Published: 22 March 2024
View article titled, Abstract 1900: TORL-3-600, a novel antibody drug conjugate directed against cadherin 17 (CDH17), has preclinical efficacy in colorectal, gastric, and pancreatic cancer
Journal Articles

Abstract 5991: Development and characterization of a novel CDK4/6 inhibitor for the treatment of CDK4/6 dependent cancers

Neil A. O'Brien, Martina S. McDermott, Brendan M. O'Boyle, Justin A. Hilf, Oliver Loson, Kevin Chau, Weiping Jia, Naeimeh Kamranpour, Tong Luo, Raul Ayala, Shawnt Issakhanian, John A. Glaspy, Brian M. Stoltz, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5991.
https://doi.org/10.1158/1538-7445.AM2023-5991
Published: 04 April 2023
View article titled, Abstract 5991: Development and characterization of a novel CDK4/6 inhibitor for the treatment of CDK4/6 dependent cancers
Journal Articles

Abstract 4044: Development of UCT-01-097, a novel orally available ERK1/2 inhibitor for the treatment of ERK1/2 dependent cancers

Neil A. O'Brien, Martina S. McDermott, Brendan M. O'Boyle, Corey M. Reeves, Michael Bartberger, Oliver Loson, Kevin Chau, Jenny J. Hong, Weiping Jia, Naeimeh Kamranpour, Tong Luo, Raul Ayala, Athena M. Madrid, John A. Glaspy, Brian M. Stoltz, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4044.
https://doi.org/10.1158/1538-7445.AM2023-4044
Published: 04 April 2023
View article titled, Abstract 4044: Development of UCT-01-097, a novel orally available ERK1/2 inhibitor for the treatment of ERK1/2 dependent cancers
Journal Articles

Abstract 342: Development and characterization of a novel anti-CLDN6 antibody drug conjugate for the treatment of CLDN6 positive cancers

Martina S. McDermott, Ke Wei Gong, Neil A. O'Brien, Dylan Conklin, Benjamin Hoffstrom, Ming Lu, Jun Zhang, Tong Luo, Weiping Jia, Jenny J. Hong, Kevin Chau, Simon Davenport, Michael F. Press, Abram Handly-Santana, Joan S. Brugge, Ronny Drapkin, John A. Glaspy, Leonard Presta, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 342.
https://doi.org/10.1158/1538-7445.AM2022-342
Published: 15 June 2022
View article titled, Abstract 342: Development and characterization of a novel anti-CLDN6 antibody drug conjugate for the treatment of CLDN6 positive cancers
Journal Articles

Abstract 332: Development of a novel therapeutic CLDN18.2 monoclonal antibody and antibody drug conjugate for the treatment of CLDN18.2 positive cancers

Neil A. O'brien, Martina S. McDermott, Jun Zhang, Ke Wei Gong, Ming Lu, Benjamin G. Hoffstrom, Dylan Conklin, Tong Luo, Kevin Chau, Min Liang, Timothy R. Donahue, John A. Glaspy, Leonard Presta, Dennis J. Slamon
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 332.
https://doi.org/10.1158/1538-7445.AM2022-332
Published: 15 June 2022
View article titled, Abstract 332: Development of a novel therapeutic CLDN18.2 monoclonal antibody and antibody drug conjugate for the treatment of CLDN18.2 positive cancers
Journal Articles

Abstract OT-13-01: A phase I study of preoperative ipilimumab, nivolumab, and talimogene laherparepvec for localized breast cancer

Vina P. Nguyen, Helena R. Chang, Maggie L. DiNome, Denise K. Oseguera, Deborah J. Wong, Anthony T. Nguyen, Stephen L. Shiao, John A. Glaspy
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): OT-13-01.
https://doi.org/10.1158/1538-7445.SABCS20-OT-13-01
Published: 15 February 2021
View article titled, Abstract OT-13-01: A phase I study of preoperative ipilimumab, nivolumab, and talimogene laherparepvec for localized breast cancer
Journal Articles

Promising activity of farnesyltransferase inhibitors across seven different sarcoma subtypes

William D. Tap, Chen Jiang, Fritz C. Eilber, Juran Kato-Stankiewicz, Jed P. Needle, Amrita Desai, John A. Glaspy, Dennis J. Slamon, Fuyuhiko Tamanoi
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 894–895.
Published: 15 April 2006
View article titled, Promising activity of farnesyltransferase inhibitors across seven different sarcoma subtypes
Journal Articles

Role of fetal calf serum (FCS) in immune responses to dendritic cell (DC)-based immunotherapy in murine models

Antoni Ribas, Begonya Comin-Anduix, Dan Vo, Vivian B. Dissette, William H. McBride, John A. Glaspy, James S. Economou
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 999–1000.
Published: 01 May 2005
View article titled, Role of fetal calf serum (FCS) in immune responses to dendritic cell (DC)-based immunotherapy in murine models
Journal Articles

Regulation of natural killer cells from CD8alpha knock-out (CD8KO) mediating strong anti-tumor responses.

Antoni Ribas, Begonya Comin-Anduix, Lana Y. Schumacher, Sharla Owens, Vivian B. Dissette, William H. McBride, John A. Glaspy, Hermes Garban, James S. Economou
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 504–505.
Published: 01 April 2004
View article titled, Regulation of natural killer cells from CD8alpha knock-out (CD8KO) mediating strong anti-tumor responses.
Journal Articles

CD40 Cross-Linking Bypasses the Absolute Requirement for CD4 T Cells during Immunization with Melanoma Antigen Gene-modified Dendritic Cells

Antoni Ribas, Lisa H. Butterfield, Saral N. Amarnani, Vivian B. Dissette, Donald Kim, Wilson S. Meng, Gustavo A. Miranda, He-Jing Wang, William H. McBride, John A. Glaspy, James S. Economou
Journal: Cancer Research
Cancer Res (2001) 61 (24): 8787–8793.
Published: 01 December 2001
View article titled, CD40 Cross-Linking Bypasses the Absolute Requirement for CD4 T Cells during Immunization with Melanoma Antigen Gene-modified Dendritic Cells
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Journal Articles

α-Fetoprotein-specific Tumor Immunity Induced by Plasmid Prime-Adenovirus Boost Genetic Vaccination

Wilson S. Meng, Lisa H. Butterfield, Antoni Ribas, Vivian B. Dissette, Justin B. Heller, Gustavo A. Miranda, John A. Glaspy, William H. McBride, James S. Economou
Journal: Cancer Research
Cancer Res (2001) 61 (24): 8782–8786.
Published: 01 December 2001
View article titled, α-Fetoprotein-specific Tumor Immunity Induced by Plasmid Prime-Adenovirus Boost Genetic Vaccination
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Journal Articles

Adenovirus-Interleukin-12-mediated Tumor Regression in a Murine Hepatocellular Carcinoma Model Is Not Dependent on CD1-restricted Natural Killer T Cells

Kahlil J. Andrews, Antoni Ribas, Lisa H. Butterfield, Charles M. Vollmer, Fritz C. Eilber, Vivian B. Dissette, Scott D. Nelson, Peter Shintaku, Shahram Mekhoubad, Toshinori Nakayama, Masaru Taniguchi, John A. Glaspy, William H. McBride, James S. Economou
Journal: Cancer Research
Cancer Res (2000) 60 (22): 6457–6464.
Published: 15 November 2000
View article titled, Adenovirus-Interleukin-12-mediated Tumor Regression in a Murine Hepatocellular Carcinoma Model Is Not Dependent on CD1-restricted Natural Killer T Cells
Open the PDF for Adenovirus-Interleukin-12-mediated Tumor Regression in a Murine Hepatocellular Carcinoma Model Is Not Dependent on CD1-restricted Natural Killer T Cells in another window
Journal Articles

Immune Deviation and Fas-mediated Deletion Limit Antitumor Activity after Multiple Dendritic Cell Vaccinations in Mice

Antoni Ribas, Lisa H. Butterfield, Billy Hu, Vivian B. Dissette, Wilson S. Meng, Andrew Koh, Kahlil J. Andrews, Maggie Lee, Saral N. Amar, John A. Glaspy, William H. McBride, James S. Economou
Journal: Cancer Research
Cancer Res (2000) 60 (8): 2218–2224.
Published: 01 April 2000
View article titled, Immune Deviation and Fas-mediated Deletion Limit Antitumor Activity after Multiple Dendritic Cell Vaccinations in Mice
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Journal Articles

p53 Selective and Nonselective Replication of an E1B-deleted Adenovirus in Hepatocellular Carcinoma

Charles M. Vollmer, Antoni Ribas, Lisa H. Butterfield, Vivian B. Dissette, Kahlil J. Andrews, Fritz C. Eilber, Lara D. Montejo, Angela Y. Chen, Billy Hu, John A. Glaspy, William H. McBride, James S. Economou
Journal: Cancer Research
Cancer Res (1999) 59 (17): 4369–4374.
Published: 01 September 1999
View article titled, p53 Selective and Nonselective Replication of an E1B-deleted Adenovirus in Hepatocellular Carcinoma
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Journal Articles

Generation of Human T-cell Responses to an HLA-A2.1-restricted Peptide Epitope Derived from α-Fetoprotein

Lisa H. Butterfield, Andrew Koh, Wilson Meng, Charles M. Vollmer, Antoni Ribas, Vivian Dissette, Eric Lee, John A. Glaspy, William H. McBride, James S. Economou
Journal: Cancer Research
Cancer Res (1999) 59 (13): 3134–3142.
Published: 01 July 1999
View article titled, Generation of Human T-cell Responses to an HLA-A2.1-restricted Peptide Epitope Derived from α-Fetoprotein
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Journal Articles

α-Fetoprotein-specific Genetic Immunotherapy for Hepatocellular Carcinoma

Charles M. Vollmer, Jr., Fritz C. Eilber, Lisa H. Butterfield, Antoni Ribas, Vivian B. Dissette, Andrew Koh, Lara D. Montejo, Maggie C. Lee, Kahlil J. Andrews, William H. McBride, John A. Glaspy, James S. Economou
Journal: Cancer Research
Cancer Res (1999) 59 (13): 3064–3067.
Published: 01 July 1999
View article titled, α-Fetoprotein-specific Genetic Immunotherapy for Hepatocellular Carcinoma
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Journal Articles

Genetic Immunization for the Melanoma Antigen MART-1/Melan-A Using Recombinant Adenovirus-transduced Murine Dendritic Cells

Antoni Ribas, Lisa H. Butterfield, William H. McBride, Syed M. Jilani, Lynne A. Bui, Charles M. Vollmer, Roy Lau, Vivian B. Dissette, Billy Hu, Angela Y. Chen, John A. Glaspy, James S. Economou
Journal: Cancer Research
Cancer Res (1997) 57 (14): 2865–2869.
Published: 01 July 1997
View article titled, Genetic Immunization for the Melanoma Antigen MART-1/Melan-A Using Recombinant Adenovirus-transduced Murine Dendritic Cells
Open the PDF for Genetic Immunization for the Melanoma Antigen MART-1/Melan-A Using Recombinant Adenovirus-transduced Murine Dendritic Cells in another window