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John A. Foekens
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Journal Articles

A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer

Wigard P. Kloosterman, Robert R.J. Coebergh van den Braak, Mark Pieterse, Markus J. van Roosmalen, Anieta M. Sieuwerts, Christina Stangl, Ronne Brunekreef, Zarina S. Lalmahomed, Salo Ooft, Anne van Galen, Marcel Smid, Armel Lefebvre, Fried Zwartkruis, John W.M. Martens, John A. Foekens, Katharina Biermann, Marco J. Koudijs, Jan N.M. Ijzermans, Emile E. Voest
Journal: Cancer Research
Cancer Res (2017) 77 (14): 3814–3822.
https://doi.org/10.1158/0008-5472.CAN-16-3563
Published: 13 July 2017
View article titled, A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer
Open the PDF for A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2530: Validation and pathway analysis of a metastasis-specific microRNA signature in primary colon cancer

Robert R. Coebergh van den Braak, Anieta M. Sieuwerts, Zarina S. Lalmahomed, Marcel Smid, Vanja de Weerd, Michelle van der Vlugt - Daane, Anne van Galen, Shanshan Xiang, Katharina Biermann, John A. Foekens, John W. Martens, Jan N. IJzermans
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2530.
https://doi.org/10.1158/1538-7445.AM2017-2530
Published: 01 July 2017
View article titled, Abstract 2530: Validation and pathway analysis of a metastasis-specific microRNA signature in primary colon cancer
Journal Articles

Abstract 4856: High mRNA expression of splice variant SYK short correlates with poor hepatic metastasis free survival in untreated lymph node negative colon cancer patients

Robert R. Coebergh van den Braak, Anieta M. Sieuwerts, Zarina S. Lalmahomed, Sandra Bril, Annemieke M. Timmermans, Vanja de Weerd, Michelle van der Vlugt - Daane, Anne van Galen, Shanshan Xiang, Katharina Biermann, John A. Foekens, John W. Martens, Jan N. IJzermans
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4856.
https://doi.org/10.1158/1538-7445.AM2017-4856
Published: 01 July 2017
View article titled, Abstract 4856: High mRNA expression of splice variant SYK short correlates with poor hepatic metastasis free survival in untreated lymph node negative colon cancer patients
Journal Articles

Abstract 490: Identification of oncogenic gene fusions in primary colon cancers

Robert R. Coebergh van den Braak, Wigard P. Kloosterman, Mark Pieterse, Markus van Roosmalen, Anieta M. Sieuwerts, Christina Stangl, Ronne Brunekreef, Zarina S. Lalmahomed, Salo Ooft, Anne van Galen, Marcel Smid, Armel Lefebvre, Fried J. Zwartkruis, John W. Martens, John A. Foekens, Katharina Biermann, Marco J. Koudijs, Jan N. IJzermans, Emile E. Voest
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 490.
https://doi.org/10.1158/1538-7445.AM2017-490
Published: 01 July 2017
View article titled, Abstract 490: Identification of oncogenic gene fusions in primary colon cancers
Journal Articles

Abstract 3938: Predicting first line tamoxifen response of recurrent ER+ breast cancer patients based on transcriptional activity of signaling pathways

Anieta M. Sieuwerts, Marcel Smid, Márcia A. Inda, John A. Foekens, Anja van de Stolpe, John W.M. Martens, Wim F.J. Verhaegh
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3938.
https://doi.org/10.1158/1538-7445.AM2016-3938
Published: 15 July 2016
View article titled, Abstract 3938: Predicting first line tamoxifen response of recurrent ER+ breast cancer patients based on transcriptional activity of signaling pathways
Journal Articles

Abstract LB-118: High APOBEC3B mRNA levels in estrogen receptor-positive primary tumors predict short time to progression for hormone-naive breast cancer patients treated with 1st line tamoxifen

Anieta M. Sieuwerts, Marion E. Meijer-van Gelder, Fred C.G.J. Sweep, Paul N. Span, John A. Foekens, John W.M. Martens
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-118.
https://doi.org/10.1158/1538-7445.AM2015-LB-118
Published: 01 August 2015
View article titled, Abstract LB-118: High APOBEC3B mRNA levels in estrogen receptor-positive primary tumors predict short time to progression for hormone-naive breast cancer patients treated with 1st line tamoxifen
Journal Articles

Abstract 1611: 4-protein signature predicts outcome to tamoxifen treatment in estrogen receptor positive recurrent breast cancer

Tommaso De Marchi, NingQing Liu, Mila Tjoa, Christoph Stingl, Marcel Smid, Maxime P. Look, Mieke A. Timmermans, Rene BH Braakman, Mark Opdam, Sabine Linn, Paul Span, Fred CGJ Sweep, John WM Martens, Theo M. Luider, John A. Foekens, Arzu Umar
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1611.
https://doi.org/10.1158/1538-7445.AM2014-1611
Published: 01 October 2014
View article titled, Abstract 1611: 4-protein signature predicts outcome to tamoxifen treatment in estrogen receptor positive recurrent breast cancer
Journal Articles

Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Maurice P.H.M. Jansen, Theo Knijnenburg, Esther A. Reijm, Iris Simon, Ron Kerkhoven, Marjolein Droog, Arno Velds, Steven van Laere, Luc Dirix, Xanthippi Alexi, John A. Foekens, Lodewyk Wessels, Sabine C. Linn, Els M.J.J. Berns, Wilbert Zwart
Journal: Cancer Research
Cancer Res (2013) 73 (22): 6632–6641.
https://doi.org/10.1158/0008-5472.CAN-13-0704
Published: 14 November 2013
View article titled, Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer
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Includes: Supplementary data
Journal Articles

Abstract P4-09-03: Comparative proteomic analysis identifies a 15-protein signature related to clinical outcome of triple negative breast cancer

Ning Qing Liu, Tommaso De Marchi, Christoph Stingl, Annemieke M Timmermans, Maxime P Look, René BH Braakman, Marcel Smid, Renée Foekens, Anita MAC Trapman, Theo M Luider, John WM Martens, John A Foekens, Arzu Umar
Journal: Cancer Research
Cancer Res (2012) 72 (24_Supplement): P4-09-03.
https://doi.org/10.1158/0008-5472.SABCS12-P4-09-03
Published: 15 December 2012
View article titled, Abstract P4-09-03: Comparative proteomic analysis identifies a 15-protein signature related to clinical outcome of triple negative breast cancer
Journal Articles

Abstract 3409: Generation of mRNA and miRNA gene expression profiles in circulating tumor cells of metastatic colorectal cancer patients

Bianca Mostert, Anieta M. Sieuwerts, Anne M. van Galen, Joan Bolt-de Vries, Jaco Kraan, Zarina Lalmahomed, Cornelis Verhoef, Jan N.M IJzermans, Vanja de Weerd, Petra van der Spoel, Raquel Ramírez-Moreno, John Jiang, Yixin Wang, Jan W. Gratama, Stefan Sleijfer, John A. Foekens, John W.M Martens
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3409.
https://doi.org/10.1158/1538-7445.AM2012-3409
Published: 15 April 2012
View article titled, Abstract 3409: Generation of mRNA and miRNA gene expression profiles in circulating tumor cells of metastatic colorectal cancer patients
Journal Articles

Abstract 806: Extracellular matrix metalloprotease inducer (EMMPRIN) and CD44 protein complexes are exclusively formed in basal- and normal-like breast cancer cell lines

Annemieke M. Timmermans, Hamed Montazeri, Anita M. Trapman-Jansen, John W. Martens, John A. Foekens, Arzu Umar
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 806.
https://doi.org/10.1158/1538-7445.AM2012-806
Published: 15 April 2012
View article titled, Abstract 806: Extracellular matrix metalloprotease inducer (EMMPRIN) and CD44 protein complexes are exclusively formed in basal- and normal-like breast cancer cell lines
Journal Articles

Abstract 5314: An oncogenic splice variant of the KLF6 tumor suppressor gene is associated with poor survival and is a potent driver of breast cancer metastasis

Raheleh Hatami, Jessica Ohlseen, Sudeh Izadmehr, Anieta M. Sieuwerts, Luena Papa, Alexander Kirschenbaum, Alice Levine, Doris Germain, John A. Foekens, Analisa DiFeo, Goutham Narla
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5314.
https://doi.org/10.1158/1538-7445.AM2012-5314
Published: 15 April 2012
View article titled, Abstract 5314: An oncogenic splice variant of the KLF6 tumor suppressor gene is associated with poor survival and is a potent driver of breast cancer metastasis
Journal Articles

Abstract 3668: Relevance of BCAR4 in tamoxifen resistance and tumor aggressiveness of breast cancer

Marcia F. E. Godinho, Anieta M. Sieuwerts, Maxime P. Look, Danielle Meijer, Stefan Sleijfer, John A. Foekens, Lambert C. J. Dorssers, Ton van Agthoven
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3668.
https://doi.org/10.1158/1538-7445.AM10-3668
Published: 15 April 2010
View article titled, Abstract 3668: Relevance of BCAR4 in tamoxifen resistance and tumor aggressiveness of breast cancer
Journal Articles

Abstract 2215: Association between acquired uniparental disomy and homozygous mutations and HER2/neu, ER, and PR status in breast cancer: Meta-analysis

Musaffe Tuna, John A. Foekens, Christopher I. Amos
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2215.
https://doi.org/10.1158/1538-7445.AM10-2215
Published: 15 April 2010
View article titled, Abstract 2215: Association between acquired uniparental disomy and homozygous mutations and HER2/neu, ER, and PR status in breast cancer: Meta-analysis
Journal Articles

Abstract SY01-04: High-end proteomics enables identification of breast cancer therapy resistance predictive proteins

Ljiljana Pasa-tolic, Theo M. Luider, John WM Martens, John A. Foekens, Arzu Umar
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): SY01-04.
https://doi.org/10.1158/1538-7445.AM10-SY01-04
Published: 15 April 2010
View article titled, Abstract SY01-04: High-end proteomics enables identification of breast cancer therapy resistance predictive proteins
Journal Articles

Copy Number Alterations that Predict Metastatic Capability of Human Breast Cancer

Yi Zhang, John W.M. Martens, Jack X. Yu, John Jiang, Anieta M. Sieuwerts, Marcel Smid, Jan G.M. Klijn, Yixin Wang, John A. Foekens
Journal: Cancer Research
Cancer Res (2009) 69 (9): 3795–3801.
https://doi.org/10.1158/0008-5472.CAN-08-4596
Published: 30 April 2009
View article titled, Copy Number Alterations that Predict Metastatic Capability of Human Breast Cancer
Open the PDF for Copy Number Alterations that Predict Metastatic Capability of Human Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1582: Identification of BCAR genes relevant for breast cancer progression and endocrine therapy resistance

Ton Van Agthoven, Jos Veldscholte, Anieta Sieuwerts, Marcel Smid, Marion E Meijer-Van Gelder, Maxime P Look, John A Foekens, Lambert C. J. Dorssers
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1582.
https://doi.org/10.1158/1538-7445.AM2008-1582
Published: 15 May 2008
View article titled, Abstract 1582: Identification of BCAR genes relevant for breast cancer progression and endocrine therapy resistance
Journal Articles

Subtypes of Breast Cancer Show Preferential Site of Relapse

Marcel Smid, Yixin Wang, Yi Zhang, Anieta M. Sieuwerts, Jack Yu, Jan G.M. Klijn, John A. Foekens, John W.M. Martens
Journal: Cancer Research
Cancer Res (2008) 68 (9): 3108–3114.
https://doi.org/10.1158/0008-5472.CAN-07-5644
Published: 01 May 2008
View article titled, Subtypes of Breast Cancer Show Preferential Site of Relapse
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Includes: Supplementary data
Journal Articles

Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics

Patrizia Sini, Ivana Samarzija, Fabienne Baffert, Amanda Littlewood-Evans, Christian Schnell, Andreas Theuer, Sven Christian, Anja Boos, Holger Hess-Stumpp, John A. Foekens, Buddy Setyono-Han, Jeanette Wood, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2008) 68 (5): 1581–1592.
https://doi.org/10.1158/0008-5472.CAN-06-4685
Published: 03 March 2008
View article titled, Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics
Open the PDF for Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics in another window
Includes: Supplementary data
Journal Articles

PITX2B mRNA expression is associated with poor prognosis in lymph node-negative steroid hormone receptor-positive breast cancer

John W. Martens, Anieta M. Sieuwerts, Marion E. Meijer-Van Gelder, Maxime P. Look, Joan Bolt-De Vries, Inko Nimmrich, Nadia Harbeck, Ralf Lesche, Oliver Hartmann, Henk Portengen, Manfred Schmitt, Sabine Maier, Jan Gm Klijn, John A. Foekens
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 847–848.
Published: 15 April 2006
View article titled, PITX2B mRNA expression is associated with poor prognosis in lymph node-negative steroid hormone receptor-positive breast cancer