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Johan Hartman
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Journal Articles

Abstract PO4-01-05: The prognostic importance of biological pathway enrichment patterns in trastuzumab-treated early HER2-positive breast cancer

Caroline Rönnlund, Qiao Yang, Caroline Schagerholm, Theodoros Foukakis, Irma Fredriksson, Xinsong Chen, Stephanie Robertson, Emmanouil Sifakis, Johan Hartman
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-01-05.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-01-05
Published: 02 May 2024
View article titled, Abstract PO4-01-05: The prognostic importance of biological pathway enrichment patterns in trastuzumab-treated early HER2-positive breast cancer
Journal Articles

Abstract PO5-13-02: BRCA mutational profiles of endocrine-resistant breast cancer

Emelie Karlsson, Caroline Schagerholm, Stephanie Robertson, Hosein Toosi, Emmanouil Sifakis, Johan Hartman
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-13-02.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-13-02
Published: 02 May 2024
View article titled, Abstract PO5-13-02: BRCA mutational profiles of endocrine-resistant breast cancer
Journal Articles

Abstract PO4-07-05: Clinical evaluation of image-based risk profiling in breast cancer histopathology and comparison to an established gene expression assay

Stephanie Robertson, Yinxi Wang, Wenwen Sun, Emelie Karlsson, Sandy Kang Lövgren, Mattias Rantalainen, Johan Hartman
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-07-05.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-07-05
Published: 02 May 2024
View article titled, Abstract PO4-07-05: Clinical evaluation of image-based risk profiling in breast cancer histopathology and comparison to an established gene expression assay
Journal Articles

Abstract PO3-16-04: Distribution of intrinsic subtypes in endocrine-resistant and endocrine-sensitive breast cancer

Caroline Schagerholm, Stephanie Robertson, Emelie Karlsson, Emmanouil Sifakis, Johan Hartman
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-16-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-16-04
Published: 02 May 2024
View article titled, Abstract PO3-16-04: Distribution of intrinsic subtypes in endocrine-resistant and endocrine-sensitive breast cancer
Journal Articles

Abstract 6185: Generative AI for virtual HE-staining of whole slide images of unstained breast cancer tissue

Leena Latonen, Umair Khan, Sonja Koivukoski, Johan Hartman, Pekka Ruusuvuori
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6185.
https://doi.org/10.1158/1538-7445.AM2024-6185
Published: 22 March 2024
View article titled, Abstract 6185: Generative AI for virtual HE-staining of whole slide images of unstained breast cancer tissue
Journal Articles

Abstract 5432: Validation of spatial gene expression patterns predicted by deep convolutional neural networks from breast cancer histopathology images

Kathy Ton, Yinxi Wang, Liuliu Pan, Kimmo Kartasalo, Balazs Acs, Philippe Weitz, Liang Zhang, Yan Liang, Johan Hartman, Masi Volkonen, Christer Larsson, Pekka Ruusuvuori, Joseph Beechem, Mattias Rantalainen
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5432.
https://doi.org/10.1158/1538-7445.AM2023-5432
Published: 04 April 2023
View article titled, Abstract 5432: Validation of spatial gene expression patterns predicted by deep convolutional neural networks from breast cancer histopathology images
Journal Articles

Abstract P2-21-02: Longitudinal tumor-immune microenvironment changes in patients with clinical luminal A early breast cancer treated with neoadjuvant palbociclib and endocrine therapy: results from the Swedish randomized PREDIX Luminal A trial

Ioannis Zerdes, Dimitrios Salgkamis, Alexios Matikas, Lars Selander, Kang Wang, Evangelos Tzoras, Emmanouil Sifakis, Susanne Agartz, Xinsong Chen, Mats Hellström, Johan Hartman, Jonas Bergh, Theodoros Foukakis, Thomas Hatschek
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-21-02.
https://doi.org/10.1158/1538-7445.SABCS22-P2-21-02
Published: 01 March 2023
View article titled, Abstract P2-21-02: Longitudinal tumor-immune microenvironment changes in patients with clinical luminal A early breast cancer treated with neoadjuvant palbociclib and endocrine therapy: results from the Swedish randomized PREDIX Luminal A trial
Journal Articles

Abstract P5-02-20: Correlative and longitudinal transcriptomic profiling predicts patient outcomes and the efficacy of neoadjuvant HER2-targeted treatments in the randomized PREDIX HER2 trial

Kang Wang, Yajing Zhu, Ioannis Zerdes, Alexios Matikas, Emmanouil Sifakis, Dimitrios Salgkamis, Judith Bjöhle, Ellinor Elinder, Sara Margolin, Ana Bosch Campos, Gyula Pekar, Henrik Lindman, Aglaia Schiza, Zakaria Einbeigi, Jamila Adra, Anne Andersson, Lena Carlsson, Ann Charlotte Dreifaldt, Erika Isaksson-Friman, Susanne Agartz, Hemming Johansson, Mats Hellström, Edward Azavedo, Johan Hartman, Jonas Bergh, Thomas Hatschek, Theodoros Foukakis
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-02-20.
https://doi.org/10.1158/1538-7445.SABCS22-P5-02-20
Published: 01 March 2023
View article titled, Abstract P5-02-20: Correlative and longitudinal transcriptomic profiling predicts patient outcomes and the efficacy of neoadjuvant HER2-targeted treatments in the randomized PREDIX HER2 trial
Journal Articles

Abstract P1-07-07: Endoresist: Prognostic and predictive gene profiles in endocrine-resistant breast cancers

Caroline Schagerholm, Stephanie Robertson, Barbro Holm, Karolina Lindberg, Emmanouil Sifakis, Linnea Hases, Cecilia Williams, Johan Hartman
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-07-07.
https://doi.org/10.1158/1538-7445.SABCS21-P1-07-07
Published: 15 February 2022
View article titled, Abstract P1-07-07: Endoresist: Prognostic and predictive gene profiles in endocrine-resistant breast cancers
Journal Articles

Abstract P3-02-06: A phase II study of 68Ga-ABY-025 PET for non-invasive quantification of HER2 expression in breast cancer

Ali Alhuseinalkhudhur, Henrik Lindman, Per Liss, Tora Sundin, Fredrik Y Frejd, Johan Hartman, Victor Iyer, Mark Lubberink, Irina Velikyan, Jens Sörensen
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-02-06.
https://doi.org/10.1158/1538-7445.SABCS21-P3-02-06
Published: 15 February 2022
View article titled, Abstract P3-02-06: A phase II study of <sup>68</sup>Ga-ABY-025 PET for non-invasive quantification of HER2 expression in breast cancer
Journal Articles

Abstract P1-02-03: Tumor-infiltrating lymphocytes but not HER2 copy number or ratio show prognostic value in trastuzumab-treated HER2-positive breast cancer

Stephanie Robertson, Caroline Rönnlund, Irma Fredriksson, Theodoros Foukakis, Johan Hartman
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P1-02-03.
https://doi.org/10.1158/1538-7445.SABCS21-P1-02-03
Published: 15 February 2022
View article titled, Abstract P1-02-03: Tumor-infiltrating lymphocytes but not HER2 copy number or ratio show prognostic value in trastuzumab-treated HER2-positive breast cancer
Journal Articles

Predicting Molecular Phenotypes from Histopathology Images: A Transcriptome-Wide Expression–Morphology Analysis in Breast Cancer

Yinxi Wang, Kimmo Kartasalo, Philippe Weitz, Balázs Ács, Masi Valkonen, Christer Larsson, Pekka Ruusuvuori, Johan Hartman, Mattias Rantalainen
Journal: Cancer Research
Cancer Res (2021) 81 (19): 5115–5126.
https://doi.org/10.1158/0008-5472.CAN-21-0482
Published: 01 October 2021
View article titled, Predicting Molecular Phenotypes from Histopathology Images: A Transcriptome-Wide Expression–Morphology Analysis in Breast Cancer
Open the PDF for Predicting Molecular Phenotypes from Histopathology Images: A Transcriptome-Wide Expression–Morphology Analysis in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PS18-27: Integrated immuno-genomic analyses in early breast cancer: Results from the Scandinavian breast group 2004-1 (SBG-2004-1) randomized phase II trial

Ioannis Zerdes, Michele Simonetti, Alexios Matikas, Luuk Harbers, Ning Zhang, Dimitrios Salgkamis, Susanne Agartz, Markella Zacharouli, Pablo Moreno-Ruiz, Johan Hartman, Artur Mezheyeuski, Jonas Bergh, Nicola Crosetto, Theodoros Foukakis
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS18-27.
https://doi.org/10.1158/1538-7445.SABCS20-PS18-27
Published: 15 February 2021
View article titled, Abstract PS18-27: Integrated immuno-genomic analyses in early breast cancer: Results from the Scandinavian breast group 2004-1 (SBG-2004-1) randomized phase II trial
Journal Articles

Abstract 2081: Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes

Linnea Hases, Rajitha Indukuri, Madeleine Birgersson, Trang Nguyen-Vu, Rodrigo Lozano, Ashish Saxena, Johan Hartman, Jonna Frasor, Jan-Åke Gustafsson, Pekka Katajisto, Amena Archer, Cecilia Williams
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2081.
https://doi.org/10.1158/1538-7445.AM2020-2081
Published: 15 August 2020
View article titled, Abstract 2081: Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes
Journal Articles

Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds

Sylvain Peuget, Jiawei Zhu, Gema Sanz, Madhurendra Singh, Massimiliano Gaetani, Xinsong Chen, Yao Shi, Amir Ata Saei, Torkild Visnes, Mikael S. Lindström, Ali Rihani, Lidia Moyano-Galceran, Joseph W. Carlson, Elisabet Hjerpe, Ulrika Joneborg, Kaisa Lehti, Johan Hartman, Thomas Helleday, Roman Zubarev, Galina Selivanova
Journal: Cancer Research
Cancer Res (2020) 80 (7): 1538–1550.
https://doi.org/10.1158/0008-5472.CAN-19-2069
Published: 02 April 2020
View article titled, Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds
Open the PDF for Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds in another window
Includes: Supplementary data
Journal Articles

Abstract P3-08-19: Biomarkers associated with dcis related breast cancer death

Charlotta Wadsten, Johan Hartman, Irma Fredriksson, Hans Garmo, Fredrik Wärnberg, Malin Sund
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-08-19.
https://doi.org/10.1158/1538-7445.SABCS19-P3-08-19
Published: 15 February 2020
View article titled, Abstract P3-08-19: Biomarkers associated with dcis related breast cancer death
Journal Articles

Abstract P5-02-07: Distribution of biomarker evaluation scores among the pathology departments of Sweden: Comparison study of 35,066 breast cancer cases

Balazs Acs, Irma Fredriksson, Ulla Wilking, Stephanie Robertson, Johan Hartman
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-02-07.
https://doi.org/10.1158/1538-7445.SABCS19-P5-02-07
Published: 15 February 2020
View article titled, Abstract P5-02-07: Distribution of biomarker evaluation scores among the pathology departments of Sweden: Comparison study of 35,066 breast cancer cases
Journal Articles

Abstract P5-02-01: Analytical validation and prognostic potential of an automated digital scoring protocol for Ki67: An International Ki67 Working Group study

Balazs Acs, Samuel C.Y. Leung, Kelley M. Kidwell, Indu Arun, Renaldas Augulis, Sunil S. Badve, Yalai Bai, Anita L. Bane, John M.S. Bartlett, Jane Bayani, Gilbert Bigras, Annika Blank, Signe Borgquist, Henk Buikema, Martin C. Chang, Robin L. Dietz, Andrew Dodson, Anna Ehinger, Susan Fineberg, Cornelia M. Focke, Dongxia Gao, Allen M. Gown, Carolina Gutierrez, Johan Hartman, Judith C. Hugh, Zuzana Kos, Anne-Vibeke Lænkholm, Arvydas Laurinavicius, Richard M. Levenson, Rustin Mahboubi-Ardakani, Mauro G. Mastropasqua, Takuya Moriya, Sharon Nofech-Mozes, C. Kent Osborne, Liron Pantanowitz, Frédérique M. Penault-Llorca, Tammy Piper, Mary Anne Quintayo, Tilman T. Rau, Stefan Reinhard, Stephanie Robertson, Takashi Sakatani, Roberto Salgado, Melanie Spears, Jane Starczynski, Tomoharu Sugie, Bert van der Vegt, Giuseppe Viale, Shakeel Virk, Lila A. Zabaglo, Daniel F. Hayes, Mitch Dowsett, Torsten O. Nielsen, David L. Rimm, International Ki67 in Breast Cancer Working Group, BIG-NABCG
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-02-01.
https://doi.org/10.1158/1538-7445.SABCS19-P5-02-01
Published: 15 February 2020
View article titled, Abstract P5-02-01: Analytical validation and prognostic potential of an automated digital scoring protocol for Ki67: An International Ki67 Working Group study
Journal Articles

Abstract P5-02-06: Improved histologic grading of breast cancer by a novel deep learning-based model

Mattias Rantalainen, Yinxi Wang, Balázs Ácz, Stephanie Robertson, Johan Hartman
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-02-06.
https://doi.org/10.1158/1538-7445.SABCS19-P5-02-06
Published: 15 February 2020
View article titled, Abstract P5-02-06: Improved histologic grading of breast cancer by a novel deep learning-based model
Journal Articles

Abstract 3933: CETSA as a diagnostic tool to guide personalized breast cancer therapy

Anette Öberg, Henriette Laursen, Sylvia Packham, Daniel Martinez Molina, Takahiro Seki, Yihai Cao, Johan Hartman, Jonas Bergh, Pär Nordlund, Sara Lööf.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3933.
https://doi.org/10.1158/1538-7445.AM2016-3933
Published: 15 July 2016
View article titled, Abstract 3933: CETSA as a diagnostic tool to guide personalized breast cancer therapy