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Joel Greshock
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Journal Articles

Abstract 6554: Prediction of MET amplification from H&E images in non small cell lung cancer using self-supervised deep learning and its role in clinical trial enrollment

Chaitanya Parmar, Oscar M. Carrasco-Zevallos, Joshua C. Curtin, Darshana Govind, Bing Xia, S. Martin Shreeve, Songbai Wang, Timothy Jatkoe, Patricia Raciti, Levon Demirdjian, Joel Greshock, Kristopher Standish, Stephen S.F. Yip
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6554.
https://doi.org/10.1158/1538-7445.AM2023-6554
Published: 04 April 2023
View articletitled, Abstract 6554: Prediction of MET amplification from H&E images in non small cell lung cancer using self-supervised deep learning and its role in clinical trial enrollment
Journal Articles

Abstract 5053: Artificial intelligence (AI)-based multimodal framework predicts androgen-deprivation therapy (ADT) outcomes in non-metastatic castration resistant prostate cancer (nmCRPC) from SPARTAN

Pooya Mobadersany, Justin Lucas, Darshana Govind, Clemente Aguilar-Bonavides, Sharon McCarthy, Sabine Brookman-May, Margaret K. Yu, Ken Tian, Natalie Hutnick, Jose Zamalloa, Joel Greshock, Najat Khan, Stephen S.F. Yip
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5053.
https://doi.org/10.1158/1538-7445.AM2022-5053
Published: 15 June 2022
View articletitled, Abstract 5053: Artificial intelligence (AI)-based multimodal framework predicts androgen-deprivation therapy (ADT) outcomes in non-metastatic castration resistant prostate cancer (nmCRPC) from SPARTAN
Journal Articles

Abstract 5006: Comprehensive gene expression analysis of the tumor microenvironment in patients with advanced cancer treated with a personalized neoantigen vaccine, NEO-PV-01, in combination with anti-PD1

Meghan E. Bushway, Ying Sonia Ting, Rana H. Besada, Tracey E. Sciuto, Jasmina Prabhakara, Julian Scherer, Kristen N. Balogh, April Lamb, Jennifer A. Kaplan, Lisa D. Cleary, Melissa A. Moles, Sarah E. Church, Yuqi Ren, Xing Ren, Richard B. Gaynor, Matthew J. Goldstein, Les H. Brail, Joel Greshock, Lakshmi Srinivasan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5006.
https://doi.org/10.1158/1538-7445.AM2019-5006
Published: 01 July 2019
View articletitled, Abstract 5006: Comprehensive gene expression analysis of the tumor microenvironment in patients with advanced cancer treated with a personalized neoantigen vaccine, NEO-PV-01, in combination with anti-PD1
Journal Articles

Abstract 942: The personalized vaccine, NEO-PV-01 with anti-PD1, induces neoantigen-specific de novo immune responses in patients with advanced metastatic melanoma: Association with clinical outcomes

Siwen Hu-Lieskovan, Patrick A. Ott, Aung Naing, Rana H. Besada, Samantha J. Gates, Victoria R. Kohler, Riley R. Curran, Meghan E. Bushway, Julian Scherer, Kristen N. Balogh, Tracey E. Sciuto, Ying S. Ting, Michael S. Rooney, Dewi Harjanto, Zhengping Huang, Yuting Huang, Yvonne Ware, April Lamb, Lisa D. Cleary, Melissa A. Moles, Richard B. Gaynor, Matthew J. Goldstein, Les H. Brail, Joel Greshock, Lakshmi Srinivasan
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 942.
https://doi.org/10.1158/1538-7445.AM2019-942
Published: 01 July 2019
View articletitled, Abstract 942: The personalized vaccine, NEO-PV-01 with anti-PD1, induces neoantigen-specific de novo immune responses in patients with advanced metastatic melanoma: Association with clinical outcomes
Journal Articles

Abstract LB-147: Comprehensive immune and molecular analysis of two metastatic melanoma patients treated with a personal neoantigen vaccine, NEO-PV-01, in combination with anti-PD1: A case study

Aung Naing, Patrick A. Ott, Samantha J. Gates, Jose G. Martinez, Riley R. Curran, Victoria L. Kohler, Meghan E. Bushway, Julian Scherer, Dominik Barthelme, Jesse Z. Dong, April Lamb, Lisa D. Cleary, Melissa Moles, Joel Greshock, Richard B. Gaynor, Matthew J. Goldstein, Lakshmi Srinivasan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-147.
https://doi.org/10.1158/1538-7445.AM2018-LB-147
Published: 01 July 2018
View articletitled, Abstract LB-147: Comprehensive immune and molecular analysis of two metastatic melanoma patients treated with a personal neoantigen vaccine, NEO-PV-01, in combination with anti-PD1: A case study
Journal Articles

Abstract CT125: A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broad de novo anti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer

Patrick A. Ott, Ramaswamy Govindan, Aung Naing, Terence W. Friedlander, Kim Margolin, Jessica J. Lin, Nina Bhardwaj, Matthew D. Hellmann, Lakshmi Srinivasan, Joel Greshock, Melissa Moles, Richard B. Gaynor, Matthew J. Goldstein, Siwen Hu-Lieskovan
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT125.
https://doi.org/10.1158/1538-7445.AM2018-CT125
Published: 01 July 2018
View articletitled, Abstract CT125: A personal neoantigen vaccine, NEO-PV-01, with anti-PD1 induces broad de novo anti-tumor immunity in patients with metastatic melanoma, NSCLC, and bladder cancer
Journal Articles

High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells

Thomas Horn, Stéphane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho, Fred Harbinski, Ali Farsidjani, Matthew Zubrowski, William R. Sellers, Robert Schlegel, Dale Porter, Erick Morris, Jens Wuerthner, Sébastien Jeay, Joel Greshock, Ensar Halilovic, Levi A. Garraway, Giordano Caponigro, Joseph Lehár
Journal: Cancer Research
Cancer Res (2016) 76 (23): 6950–6963.
https://doi.org/10.1158/0008-5472.CAN-15-3425
Published: 30 November 2016
View articletitled, High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells
Open the PDF for High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 1311: High order drug combinations are required to effectively kill colorectal cancer cells

Thomas Horn, Stephane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho, Fred Harbinski, Ali Farsidjani, Matt Zubrowski, William R. Sellers, Robert Schlegel, Dale Porter, Erick Morris, Jens Wuerthner, Sebastien Jeay, Joel Greshock, Ensar Halilovic, Levi A. Garraway, Giordano Caponigro, Joseph Lehar
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1311.
https://doi.org/10.1158/1538-7445.AM2016-1311
Published: 15 July 2016
View articletitled, Abstract 1311: High order drug combinations are required to effectively kill colorectal cancer cells
Journal Articles

Abstract 1314: Evaluation of PD-L1 mRNA and protein expression in non-small cell lung and hepatocellular carcinoma

Savina Jaeger, Benjamin H. Lee, Rebecca Mosher, Olga Shebnova, Yan Wang, Yenyen Yu, David Yang, Masato Murakami, Joel Greshock, Robert Schlegel, Anthony Boral, Zhu Alexander Cao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1314.
https://doi.org/10.1158/1538-7445.AM2015-1314
Published: 01 August 2015
View articletitled, Abstract 1314: Evaluation of PD-L1 mRNA and protein expression in non-small cell lung and hepatocellular carcinoma
Journal Articles

A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer

Ning Li, Sippy Kaur, Joel Greshock, Heini Lassus, Xiaomin Zhong, Yanling Wang, Arto Leminen, Zhongjun Shao, Xiaowen Hu, Shun Liang, Dionyssios Katsaros, Qihong Huang, Ralf Bützow, Barbara L. Weber, George Coukos, Lin Zhang
Journal: Cancer Research
Cancer Res (2012) 72 (1): 154–164.
https://doi.org/10.1158/0008-5472.CAN-11-2484
Published: 02 January 2012
View articletitled, A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer
Open the PDF for A Combined Array-Based Comparative Genomic Hybridization and Functional Library Screening Approach Identifies mir-30d As an Oncomir in Cancer in another window
Includes: Supplementary data
Journal Articles

Molecular Target Class Is Predictive of In vitro Response Profile

Joel Greshock, Kurtis E. Bachman, Yan Y. Degenhardt, Junping Jing, Yuan H. Wen, Stephen Eastman, Elizabeth McNeil, Christopher Moy, Ronald Wegrzyn, Kurt Auger, Mary Ann Hardwicke, Richard Wooster
Journal: Cancer Research
Cancer Res (2010) 70 (9): 3677–3686.
https://doi.org/10.1158/0008-5472.CAN-09-3788
Published: 28 April 2010
View articletitled, Molecular Target Class Is Predictive of In vitro Response Profile
Open the PDF for Molecular Target Class Is Predictive of In vitro Response Profile in another window
Includes: Supplementary data
Journal Articles

Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases

Fawn Qian, Stefan Engst, Kyoko Yamaguchi, Peiwen Yu, Kwang-Ai Won, Lillian Mock, Tracy Lou, Jenny Tan, Connie Li, Danny Tam, Julie Lougheed, F. Michael Yakes, Frauke Bentzien, Wei Xu, Tal Zaks, Richard Wooster, Joel Greshock, Alison H. Joly
Journal: Cancer Research
Cancer Res (2009) 69 (20): 8009–8016.
https://doi.org/10.1158/0008-5472.CAN-08-4889
Published: 14 October 2009
View articletitled, Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases
Open the PDF for Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases in another window
Includes: Supplementary data
Journal Articles

Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL

Li Liu, James Greger, Hong Shi, Yuan Liu, Joel Greshock, Roland Annan, Wendy Halsey, Ganesh M. Sathe, Anne-Marie Martin, Tona M. Gilmer
Journal: Cancer Research
Cancer Res (2009) 69 (17): 6871–6878.
https://doi.org/10.1158/0008-5472.CAN-08-4490
Published: 31 August 2009
View articletitled, Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL
Open the PDF for Novel Mechanism of Lapatinib Resistance in HER2-Positive Breast Tumor Cells: Activation of AXL in another window
Includes: Supplementary data
Journal Articles

Abstract #LB-194: Novel mechanism of resistance to HER-targeted agents in HER2+ breast tumor cells: Overexpression of the receptor tyrosine kinase AXL

James Greger, Hong Shi, Yuan Liu, Joel Greshock, Roland Annan, Wendy Halsey, Ganesh Sathe, Anne-Marie Martin, Li Liu, Tona Gilmer
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-194.
Published: 01 May 2009
View articletitled, Abstract #LB-194: Novel mechanism of resistance to HER-targeted agents in HER2+ breast tumor cells: Overexpression of the receptor tyrosine kinase AXL
Journal Articles

MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer

Nuo Yang, Sippy Kaur, Stefano Volinia, Joel Greshock, Heini Lassus, Kosei Hasegawa, Shun Liang, Arto Leminen, Shan Deng, Lori Smith, Cameron N. Johnstone, Xian-Ming Chen, Chang-Gong Liu, Qihong Huang, Dionyssios Katsaros, George Adrian Calin, Barbara L. Weber, Ralf Bützow, Carlo M. Croce, George Coukos, Lin Zhang
Journal: Cancer Research
Cancer Res (2008) 68 (24): 10307–10314.
https://doi.org/10.1158/0008-5472.CAN-08-1954
Published: 15 December 2008
View articletitled, MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer
Open the PDF for MicroRNA Microarray Identifies Let-7i as a Novel Biomarker and Therapeutic Target in Human Epithelial Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Comment re: A Comparison of DNA Copy Number Profiling Platforms

Joel Greshock, Barbara L. Weber, Bin Feng, Elena Ivanova, Ilana Perna, Alexei Protopopov, Cristina Nogueira, Lynda Chin, Katherine Nathanson
Journal: Cancer Research
Cancer Res (2008) 68 (10): 4010.
https://doi.org/10.1158/0008-5472.CAN-08-1006
Published: 15 May 2008
View articletitled, Comment re: A Comparison of DNA Copy Number Profiling Platforms
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Journal Articles

Targeted inhibition of the centromere-associated protein E (CENP-E) with GSK923295A is effective in preclinical models of human neuroblastoma.

Andrew Wood, Kristina Cole, Joshua Courtright, William Cornwell, Joel Greshock, Natalie Opsitnick, David Sutton, Aidan Gilmartin, Jeffrey Jackson, Ken Wood, Huaqing Zhao, Barbara Weber, Richard Wooster, John Maris
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2999.
Published: 01 May 2008
View articletitled, Targeted inhibition of the centromere-associated protein E (CENP-E) with GSK923295A is effective in preclinical models of human neuroblastoma.
Journal Articles

c-Myc high level amplification is associated with sensitivity to a CENP-E small molecular inhibitor, GSK923295A.

William Cornwell, Joel Greshock, Natalie Opsitnick, Liz McNeil, Galene Horiates, Randy Allen, Kenneth Wood, Aidan Gilmartin, David Sutton, Jeffrey Jackson, Barbara Weber, Richard Wooster
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3612.
Published: 01 May 2008
View articletitled, c-Myc high level amplification is associated with sensitivity to a CENP-E small molecular inhibitor, GSK923295A.
Journal Articles

A Comparison of DNA Copy Number Profiling Platforms

Joel Greshock, Bin Feng, Cristina Nogueira, Elena Ivanova, Ilana Perna, Katherine Nathanson, Alexei Protopopov, Barbara L. Weber, Lynda Chin
Journal: Cancer Research
Cancer Res (2007) 67 (21): 10173–10180.
https://doi.org/10.1158/0008-5472.CAN-07-2102
Published: 01 November 2007
View articletitled, A Comparison of DNA Copy Number Profiling Platforms
Open the PDF for A Comparison of DNA Copy Number Profiling Platforms in another window
Includes: Supplementary data
Journal Articles

A systematic study of 300 cancer cell lines to identify genome copy number and mRNA expression profiles that predict response to paclitaxel

Yan Degenhardt, William Cornwell, Yun F Hu, Joel Greshock, Randal Allen, Yifeng Chen, Barbara Weber, Richard Wooster
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 936.
Published: 01 May 2007
View articletitled, A systematic study of 300 cancer cell lines to identify genome copy number and mRNA expression profiles that predict response to paclitaxel