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Joel Cassel
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Journal Articles

Abstract 5274: Targeting retinoblastoma protein in tumor-associated macrophages suppresses ovarian cancer progression

Evgenii N. Tcyganov, Taekyoung Kwak, Xue Yang, Adi N. Poli, Colin Hart, Avishek Bhuniya, Joel Cassel, Andrew Kossenkov, Noam Auslander, Paridhima Sharma, Mark G. Cadungog, Stephanie Jean, Sudeshna Chatterjee-Paer, David Weiner, Laxminarasimha Donthireddy, Bryan Bristow, Rugang Zhang, Joseph M. Salvino, Luis J. Montaner
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5274.
https://doi.org/10.1158/1538-7445.AM2024-5274
Published: 22 March 2024
View article titled, Abstract 5274: Targeting retinoblastoma protein in tumor-associated macrophages suppresses ovarian cancer progression
Journal Articles

Abstract 4185: Neutralizing human IFN-β combined with anti-human PD-L1 and anti-human CTLA-4 treatment increased control of endometrial tumor growth in a novel HLA-A matched BLT humanized mice

Zhe Yuan, Guorui Zu, Xiao Sun, Emmanouil Papasavvas, Lily Lu, Joel Cassel, Peter L. Lutes, Mark Cadungog, Joseph Salvino, Luis J. Montaner
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4185.
https://doi.org/10.1158/1538-7445.AM2024-4185
Published: 22 March 2024
View article titled, Abstract 4185: Neutralizing human IFN-β combined with anti-human PD-L1 and anti-human CTLA-4 treatment increased control of endometrial tumor growth in a novel HLA-A matched BLT humanized mice
Journal Articles

Abstract 3457: Characterization of acquired resistance mutations to menin inhibitors

Florian Perner, Sheng F. Cai, Daniela V. Wenge, Jeonghyeon Kim, Jevon Cutler, Radosław P. Nowak, Joel Cassel, Shivendra Singh, Shipra Bijpuria, William H. Miller, Eytan M. Stein, Ross L. Levine, Eric S. Fischer, Gerard M. McGeehan, Scott A. Armstrong
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3457.
https://doi.org/10.1158/1538-7445.AM2023-3457
Published: 04 April 2023
View article titled, Abstract 3457: Characterization of acquired resistance mutations to menin inhibitors
Journal Articles

Abstract 5610: Targeting Rb1 in experimental pancreatic cancer remodels immune cell landscape and suppresses tumor progression

Evgenii N. Tcyganov, Taekyoung Kwak, Adi Narayana Reddy Poli, Laxminarasimha Donthireddy, Joel Cassel, Andrew Kossenkov, Rahul Shinde, Ben Z. Stanger, Joseph Salvino, Luis J. Montaner
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5610.
https://doi.org/10.1158/1538-7445.AM2022-5610
Published: 15 June 2022
View article titled, Abstract 5610: Targeting Rb1 in experimental pancreatic cancer remodels immune cell landscape and suppresses tumor progression
Journal Articles

Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

Joseph A. Zundell, Takeshi Fukumoto, Jianhuang Lin, Nail Fatkhudinov, Timothy Nacarelli, Andrew V. Kossenkov, Qin Liu, Joel Cassel, Chih-Chi Andrew Hu, Shuai Wu, Rugang Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5325–5335.
https://doi.org/10.1158/0008-5472.CAN-21-1545
Published: 15 October 2021
View article titled, Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <em>ARID1A</em>-Mutant Ovarian Cancers
Open the PDF for Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in <em>ARID1A</em>-Mutant Ovarian Cancers in another window
Includes: Supplementary data
Journal Articles

Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

Katelyn D. Miller, Katherine Pniewski, Caroline E. Perry, Sara B. Papp, Joshua D. Shaffer, Jesse N. Velasco-Silva, Jessica C. Casciano, Tomas M. Aramburu, Yellamelli V.V. Srikanth, Joel Cassel, Emmanuel Skordalakes, Andrew V. Kossenkov, Joseph M. Salvino, Zachary T. Schug
Journal: Cancer Research
Cancer Res (2021) 81 (5): 1252–1264.
https://doi.org/10.1158/0008-5472.CAN-20-1847
Published: 01 March 2021
View article titled, Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth
Open the PDF for Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth in another window
Includes: Supplementary data
Journal Articles

A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

Thibaut Barnoud, Jessica C. Leung, Julia I-Ju Leu, Subhasree Basu, Adi Narayana Reddy Poli, Joshua L.D. Parris, Alexandra Indeglia, Tetyana Martynyuk, Madeline Good, Keerthana Gnanapradeepan, Emilio Sanseviero, Rebecca Moeller, Hsin-Yao Tang, Joel Cassel, Andrew V. Kossenkov, Qin Liu, David W. Speicher, Dmitry I. Gabrilovich, Joseph M. Salvino, Donna L. George, Maureen E. Murphy
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5270–5281.
https://doi.org/10.1158/0008-5472.CAN-20-0397
Published: 02 December 2020
View article titled, A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors
Open the PDF for A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors in another window
Includes: Supplementary data