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Jody Vykoukal
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Journal Articles

Abstract PR-13: Disruption of sulfatide metabolism by targeting UGT8 is an actionable metabolic vulnerability for pancreatic cancer early interception

Riccardo Ballarò, Yihui Chen, Fredrik I Thege, Rongzhang Dou, Jimin Min, Michele Yip-Schneider, Jianjun Zhang, Ranran Wu, Ehsan Irajizad, Yuki Makino, Kimal I Rajapakshe, Mark W Hurd, Ricardo A León-Letelier, Edwin Ostrin, Jody Vykoukal, Jennifer B Dennison, Kim-Anh Do, Samir Hanash, Robert A Wolff, Paola A Guerrero, Michael P Kim, C Max Schmidt, Anirban Maitra, Johannes F Fahrmann
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement_2): PR-13.
https://doi.org/10.1158/1538-7445.PANCREATIC24-PR-13
Published: 15 September 2024
View articletitled, Abstract PR-13: Disruption of sulfatide metabolism by targeting UGT8 is an actionable metabolic vulnerability for pancreatic cancer early interception
Journal Articles

Abstract 446: Integrated spatial transcriptomics and lipidomics analyses of intraductal papillary mucinous neoplasm identifies enrichment of long chain sulfatide as an early metabolic alteration

Yihui Chen, Marta Sans, Fredrik Thege, Rongzhang Dou, Jimin Min, Michele Yip-Schneider, Jianjun Zhang, Ranran Wu, Ehsan Irajizad, Yuki Makino, Kimal Rajapakshe, Mark Hurd, Ricardo León-Letelier, Jody Vykoukal, Jennifer Dennison, Kim-Anh Do, Robert Wolff, Paola Guerrero, Michael Kim, Max Schmidt, Anirban Maitra, Samir Hanash, Johannes Fahrmann
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 446.
https://doi.org/10.1158/1538-7445.AM2024-446
Published: 22 March 2024
View articletitled, Abstract 446: Integrated spatial transcriptomics and lipidomics analyses of intraductal papillary mucinous neoplasm identifies enrichment of long chain sulfatide as an early metabolic alteration
Journal Articles

Abstract 6031: KYNU upregulation is a prominent feature of NRF2-activated cancers and is associated with tumor immunosuppression and poor prognosis

Ricardo A. Leon Letelier, Ali H. Abdel Sater, Yihui Chen, Ranran Wu, Jennifer B. Dennison, Soyoung Park, Ehsan Irajizad, Hiroyuki Katayama, Jody Vykoukal, Samir Hanash, Edwin J. Ostrin, Johannes F. Fahrmann
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6031.
https://doi.org/10.1158/1538-7445.AM2023-6031
Published: 04 April 2023
View articletitled, Abstract 6031: KYNU upregulation is a prominent feature of NRF2-activated cancers and is associated with tumor immunosuppression and poor prognosis
Journal Articles

Abstract 558: EGFR inhibition in lung adenocarcinoma upregulates cell surface expression of the placental antigen ALPP and enhances efficacy of ALPP-ADC therapy

Yihui Chen, Monica Hong, Hanwen Xu, Jody Vykoukal, Soyoung Park, Yining Cai, Ricardo A. León-Letelier, Fu Chung Hsiao, jennifer B. Dennison, Edwin J. Ostrin, Johannes F. Fahrmann, Hiroyuki Katayama, Samir M. Hanash
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 558.
https://doi.org/10.1158/1538-7445.AM2023-558
Published: 04 April 2023
View articletitled, Abstract 558: EGFR inhibition in lung adenocarcinoma upregulates cell surface expression of the placental antigen ALPP and enhances efficacy of ALPP-ADC therapy
Journal Articles

Abstract P1-05-26: A blood-based lipid panel for personalized risk assessment of breast cancer

Johannes Fahrmann, Ehsan Irajizad, Jody Vykoukal, Angelica Gutierrez Barrera, Jennifer Dennison, Ranran Wu, Banu K. Arun, Abenaa Brewster, Samir Hanash
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P1-05-26.
https://doi.org/10.1158/1538-7445.SABCS22-P1-05-26
Published: 01 March 2023
View articletitled, Abstract P1-05-26: A blood-based lipid panel for personalized risk assessment of breast cancer
Journal Articles

Abstract 2503: Metabolomics identifies a caveolin-1-associated plasma glycosphingolipid and sphingomyelin signature that differentiates aggressive from indolent prostate cancer in an active surveillance cohort

Johannes Fahrmann, Jody Vykoukal, Spyridon Basourakos, Jianxiang Wang, Jennifer Dennison, Eunice Murage, Jeri Kim, Timothy C. Thompson, Samir Hanash
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2503.
https://doi.org/10.1158/1538-7445.AM2017-2503
Published: 01 July 2017
View articletitled, Abstract 2503: Metabolomics identifies a caveolin-1-associated plasma glycosphingolipid and sphingomyelin signature that differentiates aggressive from indolent prostate cancer in an active surveillance cohort
Journal Articles

Abstract B70: RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells

Matthias Ilmer, Jing Wang, Alejandro Recio, Jens Werner, Alexandr Bazhin, Eckhard Alt, Jody Vykoukal
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B70.
https://doi.org/10.1158/1538-7445.PANCA16-B70
Published: 14 December 2016
View articletitled, Abstract B70: RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells
Journal Articles

Abstract 2934: TRAIL-resistance in pancreatic cancer stem cells can be regulated through JNK pathway inhibition without impacting resident stem cell physiology

Alejandro Recio Boiles, Matthias Ilmer, Jody Vykoukal, Eckhard Alt
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2934.
https://doi.org/10.1158/1538-7445.AM2015-2934
Published: 01 August 2015
View articletitled, Abstract 2934: TRAIL-resistance in pancreatic cancer stem cells can be regulated through JNK pathway inhibition without impacting resident stem cell physiology
Journal Articles

RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells

Matthias Ilmer, Alejandro Recio Boiles, Ivonne Regel, Kenji Yokoi, Christoph W. Michalski, Ignacio I. Wistuba, Jaime Rodriguez, Eckhard Alt, Jody Vykoukal
Journal: Cancer Research
Cancer Res (2015) 75 (9): 1883–1896.
https://doi.org/10.1158/0008-5472.CAN-14-1327
Published: 30 April 2015
View articletitled, RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells
Open the PDF for RSPO2 Enhances Canonical Wnt Signaling to Confer Stemness-Associated Traits to Susceptible Pancreatic Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 1930: Low surface Gal3 expression in breast cancer stem cells is associated with chemoresistance, tumorigenesis, and decreased overall patient survival

Matthias Illmer, Nachman Mazurek, James Byrd, Jody Vykoukal, Robert Scott Bresalier
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1930.
https://doi.org/10.1158/1538-7445.AM2014-1930
Published: 01 October 2014
View articletitled, Abstract 1930: Low surface Gal3 expression in breast cancer stem cells is associated with chemoresistance, tumorigenesis, and decreased overall patient survival
Journal Articles

Abstract 3355: Signaling networks in pancreatic cancer cells with stem cell characteristics

Matthias Ilmer, Jody Vykoukal, Eckhard Alt
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3355.
https://doi.org/10.1158/1538-7445.AM2012-3355
Published: 15 April 2012
View articletitled, Abstract 3355: Signaling networks in pancreatic cancer cells with stem cell characteristics