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Jitesh Pratap
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Journal Articles

Abstract 270: The novel control mechanism of the tubulin code and vesicular trafficking in breast cancer bone metastatic cells

Shreya Patel, Marcus Winogradzki, Ahmad Othman, Waddell Holmes, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 270.
https://doi.org/10.1158/1538-7445.AM2022-270
Published: 15 June 2022
View article titled, Abstract 270: The novel control mechanism of the tubulin code and vesicular trafficking in breast cancer bone metastatic cells
Journal Articles

Abstract 1240: Runx2 promotes microtubule stability for survival of breast cancer bone metastatic cells

Ahmad Othman, Marcus Winogradzki, Manish Tandon, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1240.
https://doi.org/10.1158/1538-7445.AM2020-1240
Published: 15 August 2020
View article titled, Abstract 1240: Runx2 promotes microtubule stability for survival of breast cancer bone metastatic cells
Journal Articles

Abstract 43: Regulation of autophagy in bone metastatic breast cancer cells

Ahmad H. Othman, Manish Tandon, Vivek Ashok, Marcus Winogradzki, Gary Stein, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 43.
https://doi.org/10.1158/1538-7445.AM2018-43
Published: 01 July 2018
View article titled, Abstract 43: Regulation of autophagy in bone metastatic breast cancer cells
Journal Articles

Abstract 3349: Crosstalk between Runx2 regulatory network and insulin-like growth factor receptor/Akt signaling pathway in bone metastasis of breast cancer

Manish Tandon, Zujian Chen, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3349.
https://doi.org/10.1158/1538-7445.AM2014-3349
Published: 01 October 2014
View article titled, Abstract 3349: Crosstalk between Runx2 regulatory network and insulin-like growth factor receptor/Akt signaling pathway in bone metastasis of breast cancer
Journal Articles

Abstract C40: αvβ6 integrin promotes a TGFβ1-mediated cancer cell autonomous osteolytic program through upregulation of matrix metalloproteinase 2 (MMP2)

Anindita Dutta, Jing Li, Huimin Lu, Jacqueline Akech, Jitesh Pratap, Tao Wang, Thomas J. FitzGerald, Zhong Jiang, Shelia M. Violette, Gary S. Stein, Jane B. Lian, Lucia R. Languino
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): C40.
https://doi.org/10.1158/1538-7445.TIM2013-C40
Published: 01 May 2014
View article titled, Abstract C40: αvβ6 integrin promotes a TGFβ1-mediated cancer cell autonomous osteolytic program through upregulation of matrix metalloproteinase 2 (MMP2)
Journal Articles

Integrin αvβ6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2

Anindita Dutta, Jing Li, Huimin Lu, Jacqueline Akech, Jitesh Pratap, Tao Wang, Brad J. Zerlanko, Thomas J. FitzGerald, Zhong Jiang, Ruth Birbe, John Wixted, Shelia M. Violette, Janet L. Stein, Gary S. Stein, Jane B. Lian, Lucia R. Languino
Journal: Cancer Research
Cancer Res (2014) 74 (5): 1598–1608.
https://doi.org/10.1158/0008-5472.CAN-13-1796
Published: 02 March 2014
View article titled, Integrin αvβ6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2
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Includes: Supplementary data
Journal Articles

Abstract 551: The requirement of Runx2-dependent Akt phosphorylation in breast cancer cell survival and metastasis.

Manish Tandon, Zujian Chen, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 551.
https://doi.org/10.1158/1538-7445.AM2013-551
Published: 15 April 2013
View article titled, Abstract 551: The requirement of Runx2-dependent Akt phosphorylation in breast cancer cell survival and metastasis.
Journal Articles

Abstract 3081: Crosstalk between Runx2 regulatory network and PI3K/Akt signaling pathway in breast cancer cells

Manish Tandon, Zujian Chen, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3081.
https://doi.org/10.1158/1538-7445.AM2012-3081
Published: 15 April 2012
View article titled, Abstract 3081: Crosstalk between Runx2 regulatory network and PI3K/Akt signaling pathway in breast cancer cells
Journal Articles

Abstract 4989: The role of Runx2 in epigenetic silencing of a tumor suppressor BMP-3B/GDF10 in lung cancer cells

Manish Tandon, Karthiga Gokul, Akhtar S. Ali, Jane B. Lian, Gary S. Stein, Jitesh Pratap
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4989.
https://doi.org/10.1158/1538-7445.AM2011-4989
Published: 15 April 2011
View article titled, Abstract 4989: The role of Runx2 in epigenetic silencing of a tumor suppressor BMP-3B/GDF10 in lung cancer cells
Journal Articles

Abstract 2332: Alphavbeta6 integrin, a downstream effector of TGFbeta, promotes prostate cancer osteolytic lesions

Jing Li, Jacqueline Akech, Jitesh Pratap, Tao Wang, Thomas J. FitzGerald, Zhong Jiang, Shelia M. Violette, Sadiq Hussain, Gary S. Stein, Jane B. Lian, Lucia R. Languino
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2332.
https://doi.org/10.1158/1538-7445.AM10-2332
Published: 15 April 2010
View article titled, Abstract 2332: Alphavbeta6 integrin, a downstream effector of TGFbeta, promotes prostate cancer osteolytic lesions
Journal Articles

Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression

Jitesh Pratap, Karen M. Imbalzano, Jean M. Underwood, Nathalie Cohet, Karthiga Gokul, Jacqueline Akech, Andre J. van Wijnen, Janet L. Stein, Anthony N. Imbalzano, Jeffrey A. Nickerson, Jane B. Lian, Gary S. Stein
Journal: Cancer Research
Cancer Res (2009) 69 (17): 6807–6814.
https://doi.org/10.1158/0008-5472.CAN-09-1471
Published: 31 August 2009
View article titled, Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression
Open the PDF for Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

Jitesh Pratap, John J. Wixted, Tripti Gaur, Sayyed K. Zaidi, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, Jane B. Lian
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7795–7802.
https://doi.org/10.1158/0008-5472.CAN-08-1078
Published: 30 September 2008
View article titled, Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells
Open the PDF for Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Ectopic Runx2 expression disrupts normal acini structure in mammary epithelial cells: implications for cancer progression

Jitesh Pratap, Karen Imbalzano, Nathalie Cohet, Jean Underwood, Andre van Wijnen, Janet Stein, Anthony Imbalzano, Jane Lian, Jeffrey Nickerson, Gary Stein
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2421.
Published: 01 May 2008
View article titled, Ectopic Runx2 expression disrupts normal acini structure in mammary epithelial cells: implications for cancer progression
Journal Articles

Runx2 deficiency and defective subnuclear targeting disrupt senescence pathways to promote immortalization and tumorigenic potential

Sayyed Zaidi, Sandhya Pande, Jitesh Pratap, Tripti Gaur, Simina Grigoriu, Syed Ali, Janet Stein, Jane Lian, Andre van Wijnen, Gary Stein
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1767.
Published: 01 May 2008
View article titled, Runx2 deficiency and defective subnuclear targeting disrupt senescence pathways to promote immortalization and tumorigenic potential
Journal Articles

Runx2 in breast and prostate cancer cells: Roles in adhesion, invasion and tumor activity in bone

Jitesh Pratap, Jacqueline Akech, Krystin Bedard, Michael Breen, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Lucia Languino, Jane B. Lian
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 934–935.
Published: 15 April 2006
View article titled, Runx2 in breast and prostate cancer cells: Roles in adhesion, invasion and tumor activity in bone
Journal Articles

Role of Runx2 in transcriptional regulation of MMP9 in bone metastatic cancer cells and the control of cell invasion

Jitesh Pratap, Lucia Languino, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Jane B. Lian
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1440.
Published: 01 May 2005
View article titled, Role of Runx2 in transcriptional regulation of MMP9 in bone metastatic cancer cells and the control of cell invasion
Journal Articles

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits formation of osteolytic lesions in vivo

Amjad Javed, George L. Barnes, Jitesh Pratap, Tomasz Antkowiak, Louis C. Gerstenfeld, Andre J. Van Wijnen, Janet L. Stein, Jane B. Lian, Gary S. Stein
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 684.
Published: 01 May 2005
View article titled, Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits formation of osteolytic lesions in vivo
Journal Articles

Cell Growth Regulatory Role of Runx2 during Proliferative Expansion of Preosteoblasts

Jitesh Pratap, Mario Galindo, S. Kaleem Zaidi, Diana Vradii, Bheem M. Bhat, John A. Robinson, Je-Yong Choi, Toshisha Komori, Janet L. Stein, Jane B. Lian, Gary S. Stein, Andre J. van Wijnen
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5357–5362.
Published: 18 September 2003
View article titled, Cell Growth Regulatory Role of Runx2 during Proliferative Expansion of Preosteoblasts
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Journal Articles

The CCAAT Displacement Protein/cut Homeodomain Protein Represses Osteocalcin Gene Transcription and Forms Complexes with the Retinoblastoma Protein-related Protein p107 and Cyclin A

Maria F. van Gurp, Jitesh Pratap, Mai Luong, Amjad Javed, Heidi Hoffmann, Antonio Giordano, Janet L. Stein, Ellis J. Neufeld, Jane B. Lian, Gary S. Stein, André J. van Wijnen
Journal: Cancer Research
Cancer Res (1999) 59 (23): 5980–5988.
Published: 01 December 1999
View article titled, The CCAAT Displacement Protein/<em>cut</em> Homeodomain Protein Represses Osteocalcin Gene Transcription and Forms Complexes with the Retinoblastoma Protein-related Protein p107 and Cyclin A
Open the PDF for The CCAAT Displacement Protein/<em>cut</em> Homeodomain Protein Represses Osteocalcin Gene Transcription and Forms Complexes with the Retinoblastoma Protein-related Protein p107 and Cyclin A in another window