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Journal Articles

Abstract 1169: FAT1 alterations contribute to chromosomal instability in cancer cells

Free
Wei-ting Lu, Lykourgos-Panagiotis Zalmas, Chris Bailey, James R. Black, Carlos Martinez-Ruiz, Oriol Pich, Francisco Gimeno-Valiente, Ieva Usaite, Mariam Jamal-Hanjani, Nicolas Tapon, Kasper Fugger, Nicholas McGranahan, Kevin Litchfield, Nicolai J. Birkbak, Jiri Bartek, Nnennaya Kanu, Charles Swanton
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 1169.
https://doi.org/10.1158/1538-7445.AM2025-1169
Published: 21 April 2025
View articletitled, Abstract 1169: FAT1 alterations contribute to chromosomal instability in cancer cells
Journal Articles

Abstract 4526: Inhibition of RNA Pol I transcription and induction of nucleolar stress in cancer cells treated with the experimental alpha-adrenergic receptor antagonist JP-1302

Free
Sheetanshu Saproo, Styliani Papadaki, Jaime A. Espinoza, Jiri Bartek, Mikael S. Lindström
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4526.
https://doi.org/10.1158/1538-7445.AM2024-4526
Published: 22 March 2024
View articletitled, Abstract 4526: Inhibition of RNA Pol I transcription and induction of nucleolar stress in cancer cells treated with the experimental alpha-adrenergic receptor antagonist JP-1302
Journal Articles

Abstract PR-002: Uncovering novel therapeutic avenues for glioma by exploring the functional interplay of FGFR1, p53, and ribosome biogenesis

Free
Asimina Zisi, Ewelina Dratkiewicz, Dimitris C. Kanellis, Simon Moussaud, Ida Karlsson, Helena Carén, Lars Bräutigam, Jiri Bartek, Mikael S. Lindström
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_1): PR-002.
https://doi.org/10.1158/1538-7445.BRAIN23-PR-002
Published: 04 March 2024
View articletitled, Abstract PR-002: Uncovering novel therapeutic avenues for glioma by exploring the functional interplay of FGFR1, p53, and ribosome biogenesis
Journal Articles

Abstract LB237: Functional characterisation of TRACERx reveals mechanisms of NSCLC evolution

Free
Wei-Ting Lu, Lykourgos-Panagiotis Zalmas, Chris Bailey, Oriol Pich, Carlos M. Ruiz, James Black, Georgia Stavrou, Dhruva Biswas, Francisco Gimeno-Valiente, Kevin Litchfield, Jiri Bartek, Nicholas McGranahan, Nnennaya Kanu, Charles Swanton
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB237.
https://doi.org/10.1158/1538-7445.AM2023-LB237
Published: 14 April 2023
View articletitled, Abstract LB237: Functional characterisation of TRACERx reveals mechanisms of NSCLC evolution
Journal Articles

Abstract 4814: Compensatory interplay of p97 segregase and HSP70 chaperone protect cancer cells from heat-induced proteotoxicity

Free
Zdenek Skrott, Katarina Chroma, Petr Muller, Ales Panacek, Jiri Bartek, Martin Mistrik
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4814.
https://doi.org/10.1158/1538-7445.AM2023-4814
Published: 04 April 2023
View articletitled, Abstract 4814: Compensatory interplay of p97 segregase and HSP70 chaperone protect cancer cells from heat-induced proteotoxicity
Journal Articles

Abstract 2329: Disulfiram metabolite modulates NK and T cell cytotoxicity against metastatic colorectal cancer through tumor derived NKG2D ligands

Free
Daciana Catalina Dumut, Ivo Frydrych, Miroslav Popper, Dusan Garic, Radu Alexandru Paun, Amanda Centorame, Olivia Canavan, Juhi Shah, Martin Mistrik, Petr Dzubak, Jiri Bartek, Marian Hajduch, Juan Bautista DeSanctis, Danuta Radzioch
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2329.
https://doi.org/10.1158/1538-7445.AM2023-2329
Published: 04 April 2023
View articletitled, Abstract 2329: Disulfiram metabolite modulates NK and T cell cytotoxicity against metastatic colorectal cancer through tumor derived NKG2D ligands
Journal Articles

Abstract 1251: Dithiocarb-copper complex, CuET, demonstrates anti-neoplastic activity in mouse model of prostate cancer and prevents recurrence of tumors

Free
Daciana Catalina Dumut, Juan B. DeSanctis, Martin Mistrik, Zdenek Skrott, Petr Dzubak, Jiri Bartek, Marian Hajduch, Danuta Radzioch
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1251.
https://doi.org/10.1158/1538-7445.AM2021-1251
Published: 01 July 2021
View articletitled, Abstract 1251: Dithiocarb-copper complex, CuET, demonstrates anti-neoplastic activity in mouse model of prostate cancer and prevents recurrence of tumors
Journal Articles

Abstract 5246: Disulfiram anticancer metabolite, dithiocarb-copper complex, demonstrates anti-neoplastic activity against hypermutated colorectal cancers

Free
Daciana Catalina Dumut, Juan B. De Sanctis, Martin Mistrik, Zdenek Skrott, Petr Dzubak, Jiri Bartek, Marian Hajduch, Danuta Radzioch
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5246.
https://doi.org/10.1158/1538-7445.AM2020-5246
Published: 15 August 2020
View articletitled, Abstract 5246: Disulfiram anticancer metabolite, dithiocarb-copper complex, demonstrates anti-neoplastic activity against hypermutated colorectal cancers
Journal Articles

Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress

Free
Lucy A. Young, Lenka Oplustil O'Connor, Christelle de Renty, Margaret H. Veldman-Jones, Thierry Dorval, Zena Wilson, David R. Jones, Deborah Lawson, Rajesh Odedra, Apolinar Maya-Mendoza, Corinne Reimer, Jiri Bartek, Alan Lau, Mark J. O'Connor
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (14): 3762–3775.
https://doi.org/10.1158/0008-5472.CAN-18-2480
Published: 15 July 2019
View articletitled, Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress
Open the PDF for Differential Activity of ATR and WEE1 Inhibitors in a Highly Sensitive Subpopulation of DLBCL Linked to Replication Stress in another window
Includes: Supplementary data
Journal Articles

Abstract 2678: A clonal expression biomarker improves prognostic accuracy: TRACERx lung

Free
Dhruva Biswas, Nicolai J. Birkbak, Rachel Rosenthal, Crispin T. Hiley, Emilia L. Lim, Krisztian Papp, Marcin Krzystanek, Dijana Djureinovic, Yin Wu, David A. Moore, Marcin Skrypski, Christopher Abbosh, Maise Al Bakir, Thomas B. Watkins, Selvaraju Veeriah, Gareth A. Wilson, Mariam Jamal-Hanjani, Arul M. Chinnaiyan, Patrick Micke, Jiri Bartek, Istvan Csabai, Zoltan Szallasi, Javier Herrero, Nicholas McGranahan, Charles Swanton
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2678.
https://doi.org/10.1158/1538-7445.AM2019-2678
Published: 01 July 2019
View articletitled, Abstract 2678: A clonal expression biomarker improves prognostic accuracy: TRACERx lung
Journal Articles

Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype

Free
Kaveh M. Goudarzi, Jaime A. Espinoza, Min Guo, Jiri Bartek, Monica Nistér, Mikael S. Lindström, Daniel Hägerstrand
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (20): 5901–5916.
https://doi.org/10.1158/0008-5472.CAN-18-0320
Published: 15 October 2018
View articletitled, Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype
Open the PDF for Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype in another window
Includes: Supplementary data
Journal Articles

Abstract LB-264: Alcohol-aversion drug disulfiram targets cancer via p97 segregase adaptor NPL4

Free
Martin Mistrik, Zdenek Skrott, Marian Hajduch, Søren Friis, Petr Dzubak, Jan Gursky, Dusana Majera, Tomas Ozdian, Jana Vaclavkova, Martina Michalova, Pavla Pouckova, Boris Cvek, Klaus Kaae Andersen, Jiři Bartek
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-264.
https://doi.org/10.1158/1538-7445.AM2018-LB-264
Published: 01 July 2018
View articletitled, Abstract LB-264: Alcohol-aversion drug disulfiram targets cancer via p97 segregase adaptor NPL4
Journal Articles

Abstract 2826: Differential activity of ATR and WEE1 inhibitors in DLBCL subtypes is linked to replication stress and differences in mode of action

Free
Lucy A. Young, Lenka Oplustil O'Connor, Zena Wilson, Corinne Reimer, Alan Lau, Jiri Bartek, Mark J. O'Connor
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2826.
https://doi.org/10.1158/1538-7445.AM2018-2826
Published: 01 July 2018
View articletitled, Abstract 2826: Differential activity of ATR and WEE1 inhibitors in DLBCL subtypes is linked to replication stress and differences in mode of action
Journal Articles

Abstract 1413: Replication obstacles formed within common fragile sites under replication stress are targeted by the global genomic nucleotide excision repair pathway

Free
Martin Mistrik, Lucie Beresova, Eva Vesela, Ivo Chamrad, Jiri Voller, Masayuki Yamada, Tomas Furst, Rene Lenobel, Katarina Chroma, Jan Gursky, Jiri Bartek
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1413.
https://doi.org/10.1158/1538-7445.AM2017-1413
Published: 01 July 2017
View articletitled, Abstract 1413: Replication obstacles formed within common fragile sites under replication stress are targeted by the global genomic nucleotide excision repair pathway
Journal Articles

Abstract 3598: Laser micro-irradiations of large amounts of cells for high content applications

Free
Martin Mistrik, Eva Vesela, Tomas Furst, Ivo Frydrych, Jan Gursky, Jiri Bartek
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3598.
https://doi.org/10.1158/1538-7445.AM2016-3598
Published: 15 July 2016
View articletitled, Abstract 3598: Laser micro-irradiations of large amounts of cells for high content applications
Journal Articles

Cep63 Recruits Cdk1 to the Centrosome—Letter

Free
Mohammad Alsara, Harald Löffler, Anne Fechter, Jiri Bartek, Alwin Krämer
Journal: Cancer Research
Cancer Res (2015) 75 (4): 777–778.
https://doi.org/10.1158/0008-5472.CAN-14-3431
Published: 15 February 2015
View articletitled, Cep63 Recruits Cdk1 to the Centrosome—Letter
Open the PDF for Cep63 Recruits Cdk1 to the Centrosome—Letter in another window
Journal Articles

Abstract 629: Oddities of DNA damage signaling in mitotic human cells revealed by super-resolution microscopy.

Free
Martin Mistrik, Jiri Bartek
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 629.
https://doi.org/10.1158/1538-7445.AM2013-629
Published: 15 April 2013
View articletitled, Abstract 629: Oddities of DNA damage signaling in mitotic human cells revealed by super-resolution microscopy.
Journal Articles

Abstract 3109: Correlation between genomic aberrations and the DNA damage response in bladder cancer

Free
Troels Schepeler, Philippe Lamy, Jens Laurberg, Niels Fristrup, Jirina Bartkova, Vibeke Hvidbjerg, Laurence Tropia, Jiri Bartek, Thanos D. Halazonetis, Thomas Reinert, Michael Borre, Lars Dyrskjøt, Torben F. Ørntoft
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3109.
https://doi.org/10.1158/1538-7445.AM2012-3109
Published: 15 April 2012
View articletitled, Abstract 3109: Correlation between genomic aberrations and the DNA damage response in bladder cancer
Journal Articles

Epithelial Junction Opener JO-1 Improves Monoclonal Antibody Therapy of Cancer

Free
Ines Beyer, Ruan van Rensburg, Robert Strauss, ZongYi Li, Hongjie Wang, Jonas Persson, Roma Yumul, Qinghua Feng, Hui Song, Jiri Bartek, Pascal Fender, André Lieber
Journal: Cancer Research
Cancer Res (2011) 71 (22): 7080–7090.
https://doi.org/10.1158/0008-5472.CAN-11-2009
Published: 13 November 2011
View articletitled, Epithelial Junction Opener JO-1 Improves Monoclonal Antibody Therapy of Cancer
Open the PDF for Epithelial Junction Opener JO-1 Improves Monoclonal Antibody Therapy of Cancer in another window
Includes: Supplementary data
Journal Articles

Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification, and Genome Maintenance

Free
Harald Löffler, Anne Fechter, Marc Matuszewska, Rainer Saffrich, Martin Mistrik, Joachim Marhold, Christin Hornung, Frank Westermann, Jiri Bartek, Alwin Krämer
Journal: Cancer Research
Cancer Res (2011) 71 (6): 2129–2139.
https://doi.org/10.1158/0008-5472.CAN-10-2684
Published: 14 March 2011
View articletitled, Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification, and Genome Maintenance
Open the PDF for Cep63 Recruits Cdk1 to the Centrosome: Implications for Regulation of Mitotic Entry, Centrosome Amplification, and Genome Maintenance in another window
Includes: Multimedia, Supplementary data