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Journal Articles

SMYD3 Activates Fatty Acid β-oxidation to Promote Self-Renewal of Leukemia Stem Cells

Min Zhou, Zihao Wu, Fen Wei, Chen Duan, Xiaoying Lin, Waiyi Zou, Chang Liu, Jingxuan Pan, Yanli Jin

Cancer Res (2025)

https://doi.org/10.1158/0008-5472.CAN-24-2117

Published: 13 March 2025

View article titled, SMYD3 Activates Fatty Acid β-oxidation to Promote Self-Renewal of Leukemia Stem Cells

Includes: Supplementary data

Journal Articles

Abstract 1980: S116836 overcomes BCR-ABL T315I mutation mediated imatinib resistance in chronic myeloid leukemia

Pranav Gupta, Guannan Zhang, Anna Maria Barbuti, Ke Ding, Jingxuan Pan, Brian J. Druker, Zhe-Sheng Chen

Cancer Res (2018) 78 (13_Supplement): 1980.

https://doi.org/10.1158/1538-7445.AM2018-1980

Published: 01 July 2018

View article titled, Abstract 1980: S116836 overcomes BCR-ABL T315I mutation mediated imatinib resistance in chronic myeloid leukemia

Journal Articles

Antitumor Effects of Blocking Protein Neddylation in T315I-BCR-ABL Leukemia Cells and Leukemia Stem Cells

Chang Liu, Danian Nie, Juan Li, Xin Du, Yuhong Lu, Yangqiu Li, Jingfeng Zhou, Yanli Jin, Jingxuan Pan

Cancer Res (2018) 78 (6): 1522–1536.

https://doi.org/10.1158/0008-5472.CAN-17-1733

Published: 14 March 2018

View article titled, Antitumor Effects of Blocking Protein Neddylation in T315I-BCR-ABL Leukemia Cells and Leukemia Stem Cells

Includes: Supplementary data

Journal Articles

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species

Yanli Jin, Zhongzheng Lu, Ke Ding, Juan Li, Xin Du, Chun Chen, Xiaoyong Sun, Yongbin Wu, Jing Zhou, Jingxuan Pan

Cancer Res (2010) 70 (6): 2516–2527.

https://doi.org/10.1158/0008-5472.CAN-09-3950

Published: 14 March 2010

View article titled, Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species

Includes: Supplementary data

Journal Articles

EXEL-0862, a novel tyrosine kinase inhibitor, inhibits KIT activation and induces apoptosis in human mast cells bearing mutated codon 816 c-kit in vitro and ex vivo: Therapeutic implications

Jingxuan Pan, Hagop M. Kantarjian, Manshouri Taghi, Cem Akin, Peter Lamb, Jorge E. Cortes, Francis J. Giles, Srdan Verstovsek

Cancer Res (2006) 66 (8_Supplement): 952.

Published: 15 April 2006

View article titled, EXEL-0862, a novel tyrosine kinase inhibitor, inhibits KIT activation and induces apoptosis in human mast cells bearing mutated codon 816 c-kit in vitro and ex vivo: Therapeutic implications

Journal Articles

Recent Advances in Understanding the Antineoplastic Mechanisms of Farnesyltransferase Inhibitors

Jingxuan Pan, Sai-Ching Jim Yeung

Cancer Res (2005) 65 (20): 9109–9112.

https://doi.org/10.1158/0008-5472.CAN-05-2635

Published: 17 October 2005

View article titled, Recent Advances in Understanding the Antineoplastic Mechanisms of Farnesyltransferase Inhibitors

Journal Articles

Farnesyltransferase Inhibitors Induce DNA Damage via Reactive Oxygen Species in Human Cancer Cells

Jingxuan Pan, Miaorong She, Zhi-Xiang Xu, Lily Sun, Sai-Ching Jim Yeung

Cancer Res (2005) 65 (9): 3671–3681.

https://doi.org/10.1158/0008-5472.CAN-04-2744

Published: 02 May 2005

View article titled, Farnesyltransferase Inhibitors Induce DNA Damage via Reactive Oxygen Species in Human Cancer Cells

Journal Articles

Bax dependence and enhancement by an adenovirus overexpressing Bax in anaplastic thyroid cancer cells undergoing apoptosis induced by the farnesyltransferase inhibitor manumycin A

Jingxuan Pan, Huizhi Huang, Lily Sun, Bingliang Fang, Sai-Ching Jim Yeung

Cancer Res (2005) 65 (9_Supplement): 1173.

Published: 01 May 2005

View article titled, Bax dependence and enhancement by an adenovirus overexpressing Bax in anaplastic thyroid cancer cells undergoing apoptosis induced by the farnesyltransferase inhibitor manumycin A

Journal Articles

Claspin but not Brca1 is required to mediate the gemcitabine-induced S phase checkpoint

Jingxuan Pan, William Plunkett

Cancer Res (2005) 65 (9_Supplement): 533.

Published: 01 May 2005

View article titled, Claspin but not Brca1 is required to mediate the gemcitabine-induced S phase checkpoint

Journal Articles

Phosphorylation of Chk2 and H2AX during gemcitabine-induced S-phase arrest

Brett Ewald, Jingxuan Pan, Deepa Sampath, William Plunkett

Cancer Res (2005) 65 (9_Supplement): 532.

Published: 01 May 2005

View article titled, Phosphorylation of Chk2 and H2AX during gemcitabine-induced S-phase arrest

Journal Articles

A farnesyltransferase inhibitor, manumycin A, induces DNA damage indirectly and the DNA damage response was mediated by ATM and DNA-PK but not ATR

Jingxuan Pan, Zhi-Xiang Xu, Miaorong She, Lily Sun, Sai-Ching Jim Yeung

Cancer Res (2005) 65 (9_Supplement): 1172.

Published: 01 May 2005

View article titled, A farnesyltransferase inhibitor, manumycin A, induces DNA damage indirectly and the DNA damage response was mediated by ATM and DNA-PK but not ATR

Journal Articles

Claspin, a Chk1 interacting protein, is involved in gemcitabine-induced S phase checkpoint activation.

Jingxuan Pan, Rong Chen, William Plunkett

Cancer Res (2004) 64 (7_Supplement): 538.

Published: 01 April 2004

View article titled, Claspin, a Chk1 interacting protein, is involved in gemcitabine-induced S phase checkpoint activation.

Journal Articles

Manumycin Enhances the Cytotoxic Effect of Paclitaxel on Anaplastic Thyroid Carcinoma Cells

Sai-Ching Jim Yeung, Guangpu Xu, Jingxuan Pan, Michelle Christgen, Alexander Bamiagis

Cancer Res (2000) 60 (3): 650–656.

Published: 01 February 2000

View article titled, Manumycin Enhances the Cytotoxic Effect of Paclitaxel on Anaplastic Thyroid Carcinoma Cells

NARROW

SMYD3 Activates Fatty Acid β-oxidation to Promote Self-Renewal of Leukemia Stem Cells

Abstract 1980: S116836 overcomes BCR-ABL T315I mutation mediated imatinib resistance in chronic myeloid leukemia

Antitumor Effects of Blocking Protein Neddylation in T315I-BCR-ABL Leukemia Cells and Leukemia Stem Cells

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species

EXEL-0862, a novel tyrosine kinase inhibitor, inhibits KIT activation and induces apoptosis in human mast cells bearing mutated codon 816 c-kit in vitro and ex vivo: Therapeutic implications

Recent Advances in Understanding the Antineoplastic Mechanisms of Farnesyltransferase Inhibitors

Farnesyltransferase Inhibitors Induce DNA Damage via Reactive Oxygen Species in Human Cancer Cells

Bax dependence and enhancement by an adenovirus overexpressing Bax in anaplastic thyroid cancer cells undergoing apoptosis induced by the farnesyltransferase inhibitor manumycin A

Claspin but not Brca1 is required to mediate the gemcitabine-induced S phase checkpoint

Phosphorylation of Chk2 and H2AX during gemcitabine-induced S-phase arrest

A farnesyltransferase inhibitor, manumycin A, induces DNA damage indirectly and the DNA damage response was mediated by ATM and DNA-PK but not ATR

Claspin, a Chk1 interacting protein, is involved in gemcitabine-induced S phase checkpoint activation.

Manumycin Enhances the Cytotoxic Effect of Paclitaxel on Anaplastic Thyroid Carcinoma Cells

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