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Journal Articles

TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling

Xinchao Zhang, Shuyan Li, Jing He, Yunjie Jin, Ruonan Zhang, Wenjing Dong, Mingen Lin, Yajing Yang, Tongguan Tian, Yuefan Zhou, Yixin Xu, Qun-Ying Lei, Jing Zhang, Qing Zhang, Yanping Xu, Lei Lv

Cancer Res OF1–OF13.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-3013

Published: 09 May 2022

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Includes: Supplementary data

Journal Articles

Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu, Hongquan Zhang

Cancer Res (2022) 82 (4): 735.

DOI: https://doi.org/10.1158/0008-5472.CAN-21-4346

Published: 15 February 2022

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Journal Articles

Abstract LB068: A novel CD20/CD3 T cell engager designed from Rituximab targeting CD20+ cancer with multiple mechanisms

Wenyan Cai, Jianbo Dong, Sachith Gallolu Kankanamalage, Allison Titong, Jiadong Shi, Zhejun Jia, Bo Wang, Cai Huang, Jing Zhang, Jun Lin, Steven Z. Kan, Joe Zhou, Yue Liu

Cancer Res (2021) 81 (13_Supplement): LB068.

DOI: https://doi.org/10.1158/1538-7445.AM2021-LB068

Published: 01 July 2021

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Journal Articles

Abstract 495: TNFR2 and PD-1/PD-L1/TNFR2 humanized mice aiding exploration of combination strategies to overcome tumor immune escape mechanisms

Huilin Li, Xiaofei Zhou, Jing Zhang, Veronika Chromikova, Qingcong Lin

Cancer Res (2021) 81 (13_Supplement): 495.

DOI: https://doi.org/10.1158/1538-7445.AM2021-495

Published: 01 July 2021

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Abstract 497: Human CD73 knock-in mice facilitate evaluation of in vivo efficacy of anti-human CD73 cancer immunotherapies

Chengzhang Shang, Huilin Li, Jing Zhang, Eugene Lin, Luke (Zhaoxue) Yu, Yuelei Shen

Cancer Res (2021) 81 (13_Supplement): 497.

DOI: https://doi.org/10.1158/1538-7445.AM2021-497

Published: 01 July 2021

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Journal Articles

Abstract 2954: Humanized CCR8 mouse model provides a translational tool for anti-human CCR8 antibody drug development

Linlin Wang, Chengzhang Shang, Jing Zhang, Yichao Chen, Leila Kokabee, Qingcong Lin

Cancer Res (2021) 81 (13_Supplement): 2954.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2954

Published: 01 July 2021

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Abstract 2950: Humanized C5AR1 mouse model (B-hC5AR1 mice) for evaluation of anti-C5AR1 mAb in vivo efficacy

Yanhui Nie, Xiaofei Zhou, Jing Zhang, Veronika Chromikova, Yuelei Shen

Cancer Res (2021) 81 (13_Supplement): 2950.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2950

Published: 01 July 2021

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Journal Articles

Abstract 2219: Analysis of gene landscape of small cell lung cancer of Chinese through next-generation sequencing

Jing Zhang, Hushan Zhang, Feng Ling, Yuanhan Wang, Long Li, Song Yang

Cancer Res (2021) 81 (13_Supplement): 2219.

DOI: https://doi.org/10.1158/1538-7445.AM2021-2219

Published: 01 July 2021

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Journal Articles

Abstract 1854: A Fc-competent anti-human TIGIT blocking antibody BGB-A1217 elicits strong immune responses and potent anti-tumor efficacy in pre-clinical models

Cancer Res (2021) 81 (13_Supplement): 1854.

DOI: https://doi.org/10.1158/1538-7445.AM2021-1854

Published: 01 July 2021

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Journal Articles

The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms

Yoo Jane Han, Jing Zhang, Jung-Hyun Lee, Jennifer M. Mason, Olga Karginova, Toshio F. Yoshimatsu, Qinyu Hao, Ian Hurley, Laia Paré Brunet, Aleix Prat, Kannanganattu V. Prasanth, Michaela U. Gack, Olufunmilayo I. Olopade

Cancer Res (2021) 81 (6): 1540–1551.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-1959

Published: 15 March 2021

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Includes: Supplementary data

Journal Articles

KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer

Lin Gao, Wenbo Zhang, Jing Zhang, Junmei Liu, Feifei Sun, Hui Liu, Jing Hu, Xin Wang, Xueli Wang, Peng Su, Shouzhen Chen, Sifeng Qu, Benkang Shi, Xueting Xiong, Weiwen Chen, Xuesen Dong, Bo Han

Cancer Res (2021) 81 (4): 1026–1039.

DOI: https://doi.org/10.1158/0008-5472.CAN-20-1965

Published: 15 February 2021

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Includes: Supplementary data

Journal Articles

Abstract 1377: Identification and validation of WRN as a novel synthetic lethality target in context of microsatellite instability

Cancer Res (2020) 80 (16_Supplement): 1377.

DOI: https://doi.org/10.1158/1538-7445.AM2020-1377

Published: 15 August 2020

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Journal Articles

Abstract 5733: Versican proteolytic fragments (matrikines) synergize with STING agonists to elicit robust anti-tumor CD8+ T cell responses

Athanasios Papadas, Evan Flietner, Zachary Morrow, Joshua Wiesner, Alexander Cicala, Adam Pagenkopf, Chelsea Hope, Philip Emmerich, Dustin Deming, Jing Zhang, Peiman Hematti, Natalie Callander, Alexander Rakhmilevich, Mario Otto, Christian Capitini, Fotis Asimakopoulos

Cancer Res (2020) 80 (16_Supplement): 5733.

DOI: https://doi.org/10.1158/1538-7445.AM2020-5733

Published: 15 August 2020

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Journal Articles

The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Wenhui Chu, Xi Zhang, Lihua Qi, Yenan Fu, Peng Wang, Wei Zhao, Juan Du, Jing Zhang, Jun Zhan, Yunling Wang, Wei-Guo Zhu, Yu Yu, Hongquan Zhang

Cancer Res (2020) 80 (13): 2737–2750.

DOI: https://doi.org/10.1158/0008-5472.CAN-19-3326

Published: 20 April 2020

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Journal Articles

Abstract LB-065: A high quality neoantigen fitness model cooperates with T lymphocyte infiltrates to identify glioblastoma patients with the longest survival

Jing Zhang, Francesca P. Caruso, Jason K. Sa, Sune Justesen, Do-Hyun Nam, Peter Sims, Michele Ceccarelli, Anna Lasorella, Antonio Iavarone

Cancer Res (2019) 79 (13_Supplement): LB-065.

DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-065

Published: 01 July 2019

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Journal Articles

Abstract 4134: Reversal of adenosine-mediated immune suppression by CB-708, an orally bioavailable and potent small molecule inhibitor of CD73

Cancer Res (2019) 79 (13_Supplement): 4134.

DOI: https://doi.org/10.1158/1538-7445.AM2019-4134

Published: 01 July 2019

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Journal Articles

Antagonism between HTRA3 and TGFβ1 Contributes to Metastasis in Non–Small Cell Lung Cancer

Jingya Zhao, Mingxiang Feng, Dong Liu, Haixia Liu, Mengmeng Shi, Jing Zhang, Jieming Qu

Cancer Res (2019) 79 (11): 2853–2864.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-2507

Published: 03 June 2019

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Journal Articles

Correction: Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway

Xiufeng Pang, Zhengfang Yi, Jing Zhang, Binbin Lu, Bokyung Sung, Weijing Qu, Bharat B. Aggarwal, Mingyao Liu

Cancer Res (2019) 79 (3): 685.

DOI: https://doi.org/10.1158/0008-5472.CAN-18-3859

Published: 01 February 2019

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Journal Articles

Abstract 3018: Expression of oncogenic Nras and a MYC transgene in germinal center B cells induces a highly malignant multiple myeloma

Zhi Wen, Adhithi Rajagopalan, Erik A. Ranheim, Remington Finn, Adam Pagenkopf, Grant Yun, Yun Zhou, Yidan Wang, Demin Wang, Marta Chesi, P. Leif Bergsagel, Fotis Asimakopoulos, Jing Zhang

Cancer Res (2018) 78 (13_Supplement): 3018.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3018

Published: 01 July 2018

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Journal Articles

Abstract 1373: Circular RNAs generated from the BRCA1 pseudogene regulates the DNA damage response through SERBP1 RNA-binding protein

Yoo J. Han, Jing Zhang, Jennifer M. Mason, Toshio F. Yoshimatsu, Xinxin Du, Ian Hurley, Danny E. Kim, Aparna Anantharaman, Laia P. Brunet, Aleix Prat, John Kwon, Kannanganattu V. Prasanth, Olufunmilayo I. Olopade

Cancer Res (2018) 78 (13_Supplement): 1373.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1373

Published: 01 July 2018

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2 3 4 5

NARROW

TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling

Correction: The EZH2-PHACTR2-AS1- Ribosome Axis Induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Abstract LB068: A novel CD20/CD3 T cell engager designed from Rituximab targeting CD20+ cancer with multiple mechanisms

Abstract 495: TNFR2 and PD-1/PD-L1/TNFR2 humanized mice aiding exploration of combination strategies to overcome tumor immune escape mechanisms

Abstract 497: Human CD73 knock-in mice facilitate evaluation of in vivo efficacy of anti-human CD73 cancer immunotherapies

Abstract 2954: Humanized CCR8 mouse model provides a translational tool for anti-human CCR8 antibody drug development

Abstract 2950: Humanized C5AR1 mouse model (B-hC5AR1 mice) for evaluation of anti-C5AR1 mAb in vivo efficacy

Abstract 2219: Analysis of gene landscape of small cell lung cancer of Chinese through next-generation sequencing

Abstract 1854: A Fc-competent anti-human TIGIT blocking antibody BGB-A1217 elicits strong immune responses and potent anti-tumor efficacy in pre-clinical models

The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms

KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer

Abstract 1377: Identification and validation of WRN as a novel synthetic lethality target in context of microsatellite instability

Abstract 5733: Versican proteolytic fragments (matrikines) synergize with STING agonists to elicit robust anti-tumor CD8+ T cell responses

The EZH2–PHACTR2–AS1–Ribosome Axis induces Genomic Instability and Promotes Growth and Metastasis in Breast Cancer

Abstract LB-065: A high quality neoantigen fitness model cooperates with T lymphocyte infiltrates to identify glioblastoma patients with the longest survival

Abstract 4134: Reversal of adenosine-mediated immune suppression by CB-708, an orally bioavailable and potent small molecule inhibitor of CD73

Antagonism between HTRA3 and TGFβ1 Contributes to Metastasis in Non–Small Cell Lung Cancer

Correction: Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway

Abstract 3018: Expression of oncogenic Nras and a MYC transgene in germinal center B cells induces a highly malignant multiple myeloma

Abstract 1373: Circular RNAs generated from the BRCA1 pseudogene regulates the DNA damage response through SERBP1 RNA-binding protein

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