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Journal Articles

Abstract 6070: Functional natural killer cells derived from engineered hiPSC with hypoimmunity gene combo demonstrate hypoimmunity features in evading host attacks

Jiabiao Hu, Xiangjun He, Jing Xu, Yixuan Zhou, Yanan Yue, Yangbin Gao, George Church, Luhan Yang
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6070.
https://doi.org/10.1158/1538-7445.AM2022-6070
Published: 15 June 2022
View article titled, Abstract 6070: Functional natural killer cells derived from engineered hiPSC with hypoimmunity gene combo demonstrate hypoimmunity features in evading host attacks
Journal Articles

Correction: YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation

Hsinyi Huang, Wenjing Zhang, Yafang Pan, Yijun Gao, Lei Deng, Fuming Li, Fei Li, Xueyan Ma, Shenda Hou, Jing Xu, Peixue Li, Xiaoxun Li, Guohong Hu, Cheng Li, Haiquan Chen, Lei Zhang, Hongbin Ji
Journal: Cancer Research
Cancer Res (2021) 81 (19): 5127.
https://doi.org/10.1158/0008-5472.CAN-21-2379
Published: 01 October 2021
View article titled, Correction: YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Open the PDF for Correction: YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation in another window
Journal Articles

Abstract 4151: STAT3 regulates chemo-resistance and cancer stemness in hepatocellular carcinoma

Carol Lee, Elaine Yee-Ling OR, Charing Ching-Ning Chong, Tan To Cheung, Iris Ming-Jing Xu, Linda Wing-Chi Ng, Marcus Hung-Lam Law, Peter Tin-Chung Li, Stephen Lam Chan, Anthony Wing-Hung Chan, Philip Chun Yeung, Kelvin Kwok-Chai Ng, Paul Bo-San Lai, Siu Tim Cheung
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4151.
https://doi.org/10.1158/1538-7445.AM2020-4151
Published: 15 August 2020
View article titled, Abstract 4151: STAT3 regulates chemo-resistance and cancer stemness in hepatocellular carcinoma
Journal Articles

Abstract 882: Thioredoxin system inhibition using auranofin represents a new therapeutic approach for hepatocellular carcinoma

Derek Lee, Iris Ming-Jing Xu, David Kung-Chun Chiu, Robin Kit-Ho Lai, Chun-Ming Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 882.
https://doi.org/10.1158/1538-7445.AM2019-882
Published: 01 July 2019
View article titled, Abstract 882: Thioredoxin system inhibition using auranofin represents a new therapeutic approach for hepatocellular carcinoma
Journal Articles

Correction: Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC

Haoyu Sun, Jing Xu, Qiang Huang, Mei Huang, Kun Li, Kun Qu, Hao Wen, Renyong Lin, Meijuan Zheng, Haiming Wei, Weihua Xiao, Rui Sun, Zhigang Tian, Cheng Sun
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1714.
https://doi.org/10.1158/0008-5472.CAN-19-0630
Published: 01 April 2019
View article titled, Correction: Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC
Open the PDF for Correction: Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC in another window
Journal Articles

Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC

Haoyu Sun, Jing Xu, Qiang Huang, Mei Huang, Kun Li, Kun Qu, Hao Wen, Renyong Lin, Meijuan Zheng, Haiming Wei, Weihua Xiao, Rui Sun, Zhigang Tian, Cheng Sun
Journal: Cancer Research
Cancer Res (2018) 78 (23): 6581–6593.
https://doi.org/10.1158/0008-5472.CAN-18-1049
Published: 03 December 2018
View article titled, Reduced CD160 Expression Contributes to Impaired NK-cell Function and Poor Clinical Outcomes in Patients with HCC
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Includes: Supplementary data
Journal Articles

Abstract 134: Dysbiosis of gut microbiota in chronic stressed patients with endometriosis

Jing Xu, Yu Kang, Yinhua Yu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 134.
https://doi.org/10.1158/1538-7445.AM2018-134
Published: 01 July 2018
View article titled, Abstract 134: Dysbiosis of gut microbiota in chronic stressed patients with endometriosis
Journal Articles

Abstract 2415: HEY1 counteracts hypoxia-induced oxidative stress via transcriptionally repressing PINK1 in hepatocellular carcinoma

David Kung-Chun Chiu, Iris Ming-Jing Xu, Robin Kit-Ho Lai, Aki Pui-Wah Tse, Dicky Cheuk-Ting Law, Vincent Wai-Hin Yuen, Larry Lai Wei, Hui-Yu Koh, Chun-Ming Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2415.
https://doi.org/10.1158/1538-7445.AM2018-2415
Published: 01 July 2018
View article titled, Abstract 2415: HEY1 counteracts hypoxia-induced oxidative stress via transcriptionally repressing PINK1 in hepatocellular carcinoma
Journal Articles

Abstract 2445: Oxidative stress induction through TXNRD1 inhibition as a therapeutic strategy in hepatocellular carcinoma treatment

Derek Lee, Iris Ming Jing Xu, David Kung Chun Chiu, Robin Kit Ho Lai, Chun Ming Wong, Irene Oi Lin Ng, Carmen Chak Lui Wong
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2445.
https://doi.org/10.1158/1538-7445.AM2018-2445
Published: 01 July 2018
View article titled, Abstract 2445: Oxidative stress induction through TXNRD1 inhibition as a therapeutic strategy in hepatocellular carcinoma treatment
Journal Articles

YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation

Hsinyi Huang, Wenjing Zhang, Yafang Pan, Yijun Gao, Lei Deng, Fuming Li, Fei Li, Xueyan Ma, Shenda Hou, Jing Xu, Peixue Li, Xiaoxun Li, Guohong Hu, Cheng Li, Haiquan Chen, Lei Zhang, Hongbin Ji
Journal: Cancer Research
Cancer Res (2017) 77 (21): 5769–5781.
https://doi.org/10.1158/0008-5472.CAN-17-0449
Published: 31 October 2017
View article titled, YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation
Open the PDF for YAP Suppresses Lung Squamous Cell Carcinoma Progression via Deregulation of the DNp63–GPX2 Axis and ROS Accumulation in another window
Includes: Supplementary data
Journal Articles

Abstract 436: Folate cycle represents a new metabolic vulnerability for hepatocellular carcinoma treatment

Derek Lee, Iris Ming-Jing Xu, David Kung-Chun Chiu, Robin Kit-Ho Lai, Chun-Ming Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 436.
https://doi.org/10.1158/1538-7445.AM2017-436
Published: 01 July 2017
View article titled, Abstract 436: Folate cycle represents a new metabolic vulnerability for hepatocellular carcinoma treatment
Journal Articles

Abstract 2941: Inhibition of hypoxia-induced ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2) restrains myeloid-derived suppressor cell (MDSC) accumulation and sensitizes tumors to immune checkpoint inhibition

David Kung-Chun Chiu, Aki Pui-Wah Tse, Iris Ming-Jing Xu, Robin Kit-Ho Lai, Hui-yu Koh, Felice Ho-Ching Tsang, Larry Lai Wei, Chun-Ming Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2941.
https://doi.org/10.1158/1538-7445.AM2017-2941
Published: 01 July 2017
View article titled, Abstract 2941: Inhibition of hypoxia-induced ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2) restrains myeloid-derived suppressor cell (MDSC) accumulation and sensitizes tumors to immune checkpoint inhibition
Journal Articles

Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer

Longchuan Bai, Bing Zhou, Chao-Yie Yang, Jiao Ji, Donna McEachern, Sally Przybranowski, Hui Jiang, Jiantao Hu, Fuming Xu, Yujun Zhao, Liu Liu, Ester Fernandez-Salas, Jing Xu, Yali Dou, Bo Wen, Duxin Sun, Jennifer Meagher, Jeanne Stuckey, Daniel F. Hayes, Shunqiang Li, Matthew J. Ellis, Shaomeng Wang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (9): 2476–2487.
https://doi.org/10.1158/0008-5472.CAN-16-2622
Published: 30 April 2017
View article titled, Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer
Open the PDF for Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 1058: Targeting pentose phosphate pathway (PPP) represents a novel therapeutic strategy for hepatocellular carcinoma (HCC) treatment

Ming Jing Xu, Kit Ho Lai, Shu Hai Lin, Pui Wah Tse, David Kung Chun Chiu, Hui Yu Koh, Cheuk Ting Law, Chun Ming Wong, Zong Wei Cai, Carmen Chak Lui Wong, Irene Oi Lin Ng
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1058.
https://doi.org/10.1158/1538-7445.AM2016-1058
Published: 15 July 2016
View article titled, Abstract 1058: Targeting pentose phosphate pathway (PPP) represents a novel therapeutic strategy for hepatocellular carcinoma (HCC) treatment
Journal Articles

Abstract 2283: Molecular signaling in multiple myeloma: association of RAS/RAF mutation status and MAPK pathway activation in primary myeloma patient biopsies

Jing Xu, Nicole Pfarr, Volker Endris, Elias K. Mai, Nur Hafzan Md Hanafiah, Nicola Lehners, Roland Penzel, Wilko Weichert, Anthony D. Ho, Peter Schirmacher, Hartmut Goldschmidt, Mindaugas Andrulis, Marc S. Raab
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2283.
https://doi.org/10.1158/1538-7445.AM2016-2283
Published: 15 July 2016
View article titled, Abstract 2283: Molecular signaling in multiple myeloma: association of RAS/RAF mutation status and MAPK pathway activation in primary myeloma patient biopsies
Journal Articles

Abstract 3346: Testing the cancer stem cell hypothesis using the hybrid spheroid assay and Koch's postulates

Christopher S. Lange, Talal Syed, Mike Zhang, Christian Sabalvaro, Hana I. Lim, Ghadir Salame, Bhargava Chitti, Ifeanyi Ilonzo, Arsalaan Ansari, Michelle Chan, Catherine Li, Jing Xu, Xiaotong Chen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3346.
https://doi.org/10.1158/1538-7445.AM2016-3346
Published: 15 July 2016
View article titled, Abstract 3346: Testing the cancer stem cell hypothesis using the hybrid spheroid assay and Koch's postulates
Journal Articles

Abstract 4399: Hypoxia as a driver of myeloid-derived suppressor cell recruitment in hepatocellular carcinoma via CCL26/CX3CR1

David Kung-Chun Chiu, Iris Ming-Jing Xu, Robin Kit-Ho Lai, Aki Pui-Wah Tse, Larry Lai Wei, Hui-Yu Koh, Regina Cheuk-Lam Lo, Chun-Ming Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4399.
https://doi.org/10.1158/1538-7445.AM2016-4399
Published: 15 July 2016
View article titled, Abstract 4399: Hypoxia as a driver of myeloid-derived suppressor cell recruitment in hepatocellular carcinoma via CCL26/CX3CR1
Journal Articles

Abstract LB-310: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4-like 2 (NDUFA4L2) reduces oxidative stress to promote hepatocellular carcinoma

Robin Kit-Ho Lai, Irix Ming-Jing Xu, David Kung-Chun Chiu, Aki Pui-Wah Tse, Larry Lai Wei, Cheuk-Ting Law, Derek Lee, Chun-Ming Wong, Maria Pik Wong, Irene Oi-Lin Ng, Carmen Chak Lui Wong.
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-310.
https://doi.org/10.1158/1538-7445.AM2016-LB-310
Published: 15 July 2016
View article titled, Abstract LB-310: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4-like 2 (NDUFA4L2) reduces oxidative stress to promote hepatocellular carcinoma
Journal Articles

Abstract 2423: Signaling pathway profiling in multiple myeloma

Jing Xu, Thomas Hielscher, Nicola Lehners, Elena Ellert, Anthony D. Ho, Peter Schirmacher, Hartmut Goldschmidt, Mindaugas Andrulis, Marc-Steffen Raab
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2423.
https://doi.org/10.1158/1538-7445.AM2015-2423
Published: 01 August 2015
View article titled, Abstract 2423: Signaling pathway profiling in multiple myeloma
Journal Articles

Abstract 1188: HIF-1α/NDUFA4L2 promotes hepatocellular carcinoma progression through reducing oxidative stress

Kit Ho Lai, Ming Jing Xu, Pui Wah Tse, Kung Chun Chiu, Wei Lai, Chun Ming Wong, Pik Wong, Oi Lin Ng, Chak Lui Wong
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1188.
https://doi.org/10.1158/1538-7445.AM2015-1188
Published: 01 August 2015
View article titled, Abstract 1188: HIF-1α/NDUFA4L2 promotes hepatocellular carcinoma progression through reducing oxidative stress