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Journal Articles

The Circadian Clock Component RORA Increases Immunosurveillance in Melanoma by Inhibiting PD-L1 Expression

Dandan Liu, Benliang Wei, Long Liang, Yue Sheng, Shengjie Sun, Xing Sun, Maohua Li, Haobo Li, Chaoying Yang, Yuanliang Peng, Yifang Xie, Chengcai Wen, Lu Chen, Xionghao Liu, Xiang Chen, Hong Liu, Jing Liu
Journal: Cancer Research
Cancer Res (2024) 84 (14): 2265–2281.
https://doi.org/10.1158/0008-5472.CAN-23-3942
Published: 15 July 2024
View article titled, The Circadian Clock Component RORA Increases Immunosurveillance in Melanoma by Inhibiting PD-L1 Expression
Open the PDF for The Circadian Clock Component RORA Increases Immunosurveillance in Melanoma by Inhibiting PD-L1 Expression in another window
Includes: Supplementary data
Journal Articles

Abstract LB302: circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR

Liling Niu, Jing Liu, Hui Li
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB302.
https://doi.org/10.1158/1538-7445.AM2024-LB302
Published: 05 April 2024
View article titled, Abstract LB302: circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR
Journal Articles

Abstract 5742: Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

James D. Thomas, Sydney X. Lu, Emma De Neef, Erich Sabio, Benoit Rousseau, Mathieu Gigoux, David A. Knorr, Benjamin Greenbaum, Yuval Elhanati, Simon J. Hogg, Andrew Chow, Arnab Ghosh, Abigail Xie, Dmitriy Zamarin, Daniel Cui, Caroline Erickson, Michael Singer, Hana Cho, Eric Wang, Bin Lu, Benjamin H. Durham, Harshal Shah, Diego Chowell, Austin M. Gabel, Yudao Shen, Jing Liu, Jian Jin, Matthew C. Rhodes, Richard E. Taylor, Henrik Molina, Jedd D. Wolchok, Taha Merghoub, Luis A. Diaz Jr, Omar Abdel-Wahab, Robert K. Bradley
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5742.
https://doi.org/10.1158/1538-7445.AM2023-5742
Published: 04 April 2023
View article titled, Abstract 5742: Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
Journal Articles

Abstract P5-10-01: Phase 2 study of anlotinib combined with taxanes and lobaplatin in the neoadjuvant treatment of triple-negative breast cancer: efficacy, safety and biomarker analysis from the SWH-B006 (neoALTALL) trial

Yan Liang, Jing Liu, Tao Luo, Jia Ge, Hao Tian, Guozhi Zhang, Linjun Fan, Lin Ren, Li Chen, Peng Tang, Kai Zhu, Xiuwu Bian, Jun Jiang, Yi Zhang, Xiaowei Qi, Peng Tang, Kai Zhu, Xiuwu Bian, Jun Jiang, Yi Zhang, Xiaowei Qi
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-10-01.
https://doi.org/10.1158/1538-7445.SABCS22-P5-10-01
Published: 01 March 2023
View article titled, Abstract P5-10-01: Phase 2 study of anlotinib combined with taxanes and lobaplatin in the neoadjuvant treatment of triple-negative breast cancer: efficacy, safety and biomarker analysis from the SWH-B006 (neoALTALL) trial
Journal Articles

Abstract LB195: AKT degradation selectively inhibits the growth of PI3K/PTEN pathway mutant cancers with wild type KRAS and BRAF by destabilizing Aurora kinase B

Jia Xu, Xufen Yu, Tiphaine C. Martin, Ankita Bansal, Kakit Cheung, Abigail Lubin, Elias Stratikopoulos, Kaitlyn M. Cahuzac, Li Wang, Ling Xie, Royce Zhou, Yudao Shen, Xuewei Wu, Shen Yao, Ruifang Qiao, Poulikos I. Poulikakos, Xian Chen, Jing Liu, Jian Jin, Ramon Parsons
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB195.
https://doi.org/10.1158/1538-7445.AM2022-LB195
Published: 15 June 2022
View article titled, Abstract LB195: AKT degradation selectively inhibits the growth of PI3K/PTEN pathway mutant cancers with wild type KRAS and BRAF by destabilizing Aurora kinase B
Journal Articles

Multilevel Regulation of β-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma

Hanyu Rao, Xiaoxue Li, Min Liu, Jing Liu, Wenxin Feng, Huayuan Tang, Jin Xu, Wei-Qiang Gao, Li Li
Journal: Cancer Research
Cancer Res (2021) 81 (13): 3554–3567.
https://doi.org/10.1158/0008-5472.CAN-20-3960
Published: 01 July 2021
View article titled, Multilevel Regulation of β-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma
Open the PDF for Multilevel Regulation of β-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 326: Structural dynamics-based hit generation to disrupt YAP/TAZ-TEAD protein-protein interaction

Lin Du, Jing Liu, Qinglong Zeng, Ming Xu, Jiting Lu, Qiangang Zheng, Jidong Zhu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 326.
https://doi.org/10.1158/1538-7445.AM2021-326
Published: 01 July 2021
View article titled, Abstract 326: Structural dynamics-based hit generation to disrupt YAP/TAZ-TEAD protein-protein interaction
Journal Articles

Abstract 5331: Targeted protein degradation for the treatment of TRK fusion-driven cancers

Xiaoran Han, Liqun Chen, Chengwei Zhang, Bingyang Jiao, Yanke Chen, Jing Liu, Michael Plewe, Jialiang Wang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5331.
https://doi.org/10.1158/1538-7445.AM2020-5331
Published: 15 August 2020
View article titled, Abstract 5331: Targeted protein degradation for the treatment of TRK fusion-driven cancers
Journal Articles

Abstract P3-03-14: Screening strategies for Notch3-degradation-related E3 ligase in breast cancers

Jing Liu, Man-Li Zhang, Jia-Xin Shen, Ya Xu, Ming-Heng Yuan, Guo-Jun Zhang
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P3-03-14.
https://doi.org/10.1158/1538-7445.SABCS19-P3-03-14
Published: 15 February 2020
View article titled, Abstract P3-03-14: Screening strategies for Notch3-degradation-related E3 ligase in breast cancers
Journal Articles

Abstract P5-03-05: Comprehensive analysis of the prevalence of germline mutations and their association with somatic mutations in Chinese unselected breast cancer patients

Ning Liao, Bo Chen, Guochun Zhang, Chongyang Ren, Yulei Wang, Liping Guo, Li Cao, Lingzhu Wen, Kai Li, Minghan Jia, Cheukfai Li, Hsiaopei Mok, Guangnan Wei, Jiali Lin, Zhou Zhang, Ting Hou, Analyn Lizaso, Jing Liu
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-03-05.
https://doi.org/10.1158/1538-7445.SABCS19-P5-03-05
Published: 15 February 2020
View article titled, Abstract P5-03-05: Comprehensive analysis of the prevalence of germline mutations and their association with somatic mutations in Chinese unselected breast cancer patients
Journal Articles

Abstract LB-302: Whole genome sequencing reveals a significant role of ZNFs-PHLPP2-AKT axis in familial breast cancer of chaoshan area

Can-Bin Fang, Qian-Qian Ye, Jing Liu, Guo-Jun Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-302.
https://doi.org/10.1158/1538-7445.AM2019-LB-302
Published: 01 July 2019
View article titled, Abstract LB-302: Whole genome sequencing reveals a significant role of ZNFs-PHLPP2-AKT axis in familial breast cancer of chaoshan area
Journal Articles

Abstract 1325: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses

Wei Deng, Dayong Zhai, Evan Rogers, Xin Zhang, Dong Lee, Jane Ung, Han Zhang, Jing Liu, Yuelie Lu, John Huang, Armin Graber, Zach Zimmerman, John Lim, Jeffrey Whitten, J. Jean Cui
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1325.
https://doi.org/10.1158/1538-7445.AM2019-1325
Published: 01 July 2019
View article titled, Abstract 1325: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC inhibits tumor growth by promoting anti-tumor immune responses
Journal Articles

Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling

Dayong Zhai, Evan Rogers, Wei Deng, Xin Zhang, Dong Lee, Jane Ung, Han Zhang, Jing Liu, Yuelie Lu, John Huang, Armin Graber, Zach Zimmerman, John Lim, Jeffrey Whitten, J. Jean Cui
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1321.
https://doi.org/10.1158/1538-7445.AM2019-1321
Published: 01 July 2019
View article titled, Abstract 1321: TPX-0022, a polypharmacology inhibitor of MET/CSF1R/SRC for treatment of cancers with abnormal HGF/MET signaling
Journal Articles

Abstract 338: Inhibition of phosphatidylinositol 3-kinase signaling antagonizes paclitaxel-mediated resistance in cervical cancer

Youn Jin Choi, Yoo Yeon Jung, Jing Jing Liu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 338.
https://doi.org/10.1158/1538-7445.AM2019-338
Published: 01 July 2019
View article titled, Abstract 338: Inhibition of phosphatidylinositol 3-kinase signaling antagonizes paclitaxel-mediated resistance in cervical cancer
Journal Articles

Molecular Imaging of Deoxycytidine Kinase Activity Using Deoxycytidine-Enhanced CEST MRI

Zheng Han, Yuguo Li, Jia Zhang, Jing Liu, Chuheng Chen, Peter C. van Zijl, Guanshu Liu
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2775–2783.
https://doi.org/10.1158/0008-5472.CAN-18-3565
Published: 15 May 2019
View article titled, Molecular Imaging of Deoxycytidine Kinase Activity Using Deoxycytidine-Enhanced CEST MRI
Open the PDF for Molecular Imaging of Deoxycytidine Kinase Activity Using Deoxycytidine-Enhanced CEST MRI in another window
Includes: Supplementary data
Journal Articles

PAK4 Phosphorylates Fumarase and Blocks TGFβ-Induced Cell Growth Arrest in Lung Cancer Cells

Tao Chen, Ting Wang, Wenhua Liang, Qin Zhao, Qiujing Yu, Chun-Min Ma, Lingang Zhuo, Dong Guo, Ke Zheng, Chengzhi Zhou, Shupei Wei, Wenhua Huang, Juhong Jiang, Jing Liu, Shiyue Li, Jianxing He, Yuhui Jiang, Nanshan Zhong
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (7): 1383–1397.
https://doi.org/10.1158/0008-5472.CAN-18-2575
Published: 01 April 2019
View article titled, PAK4 Phosphorylates Fumarase and Blocks TGFβ-Induced Cell Growth Arrest in Lung Cancer Cells
Open the PDF for PAK4 Phosphorylates Fumarase and Blocks TGFβ-Induced Cell Growth Arrest in Lung Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 2003: P38α suppresses tumor initiating cell phenotypes through inhibition of NFATc4 in non-small cell lung cancer

Zhi-Jie Xiao, Jing Liu, Si-Qi Wang, Xu-Yuan Gao, Vicky Pui-Chi Tin, Maria Pik Wong
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2003.
https://doi.org/10.1158/1538-7445.AM2018-2003
Published: 01 July 2018
View article titled, Abstract 2003: P38α suppresses tumor initiating cell phenotypes through inhibition of NFATc4 in non-small cell lung cancer
Journal Articles

Abstract 4197: Interaction of B lymphoma cells with the microenvironment affects ibrutinib sensitivity

Hsu-Ping Kuo, Sidney Hsieh, Mint Sirisawad, Chun-Te Chen, Leo W. Cheung, Karl J. Schweighofer, Chia-Lin Hsu, Chi-Ling Fu, Jing Liu, Shiquan Wu, Karl Eckert, Hugh Wang, Mutiah Apatira, Kamaldeep Dhami, Kevin Kwei, Jeff Hsu, Betty Y. Chang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4197.
https://doi.org/10.1158/1538-7445.AM2017-4197
Published: 01 July 2017
View article titled, Abstract 4197: Interaction of B lymphoma cells with the microenvironment affects ibrutinib sensitivity
Journal Articles

Abstract 1818: Enhanced antitumor and anti-angiogenic effects of Apatinib combined with chemotherapy in a zebrafish model of non-small cell lung cancer

Yi Xiang, Wenchao Zhang, Zhuanbin Wu, Zijun Qian, Jianping Zhou, Xiaofei Wang, Weiqin Wang, Ling Zhou, Jing Liu, Yun Feng, Min Zhou, Guochao Shi, Beili Gao
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1818.
https://doi.org/10.1158/1538-7445.AM2017-1818
Published: 01 July 2017
View article titled, Abstract 1818: Enhanced antitumor and anti-angiogenic effects of Apatinib combined with chemotherapy in a zebrafish model of non-small cell lung cancer
Journal Articles

Abstract 167: Ibrutinib regulates tumor microenvironment and enhances response to everolimus in renal cell carcinoma mouse models

Jun Chen, Chun-Te Chen, Jing Liu, Jeff Hsu, Taisei Kinoshita, Betty Y. Chang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 167.
https://doi.org/10.1158/1538-7445.AM2017-167
Published: 01 July 2017
View article titled, Abstract 167: Ibrutinib regulates tumor microenvironment and enhances response to everolimus in renal cell carcinoma mouse models