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Jill E. Larsen
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Journal Articles

Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells

Free
Tonya C. Walser, Zhe Jing, Linh M. Tran, Ying Q. Lin, Natalie Yakobian, Gerald Wang, Kostyantyn Krysan, Li X. Zhu, Sherven Sharma, Mi-Heon Lee, John A. Belperio, Aik T. Ooi, Brigitte N. Gomperts, Jerry W. Shay, Jill E. Larsen, John D. Minna, Long-sheng Hong, Michael C. Fishbein, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2018) 78 (8): 1986–1999.
https://doi.org/10.1158/0008-5472.CAN-17-0315
Published: 12 April 2018
View articletitled, Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells
Open the PDF for Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 3950: A novel combination therapy targeting BCL6 and phospho-STAT3 defeats intratumor heterogeneity in a subset of non-small cell lung cancers

Free
Dhruba Deb, Satwik Rajaram, Jill E. Larsen, Patrick P. Dospoy, Rossella Marullo, Longshan Li, Kimberley Avila, Leandro Cerchietti, John D. Minna, Lani F. Wu, Steven J. Altschuler
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3950.
https://doi.org/10.1158/1538-7445.AM2017-3950
Published: 01 July 2017
View articletitled, Abstract 3950: A novel combination therapy targeting BCL6 and phospho-STAT3 defeats intratumor heterogeneity in a subset of non-small cell lung cancers
Journal Articles

Abstract 3328: Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis

Free
Xiaorong Zhou, Barrett L. Updegraff, Yabin Guo, Michael Peyton, Luc Girard, Jill E. Larsen, Xian-Jin Xie, Yunyun Zhou, Tae Hyun Hwang, Yang Xie, Jaime Rodriguez-Canales, Pamela Villalobos, Carmen Behrens, Wistuba I. Ignacio, John D. Minna, Kathryn A. O'Donnell
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3328.
https://doi.org/10.1158/1538-7445.AM2017-3328
Published: 01 July 2017
View articletitled, Abstract 3328: Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis
Journal Articles

Combination Therapy Targeting BCL6 and Phospho-STAT3 Defeats Intratumor Heterogeneity in a Subset of Non–Small Cell Lung Cancers

Free
Dhruba Deb, Satwik Rajaram, Jill E. Larsen, Patrick D. Dospoy, Rossella Marullo, Long Shan Li, Kimberley Avila, Fengtian Xue, Leandro Cerchietti, John D. Minna, Steven J. Altschuler, Lani F. Wu
Journal: Cancer Research
Cancer Res (2017) 77 (11): 3070–3081.
https://doi.org/10.1158/0008-5472.CAN-15-3052
Published: 31 May 2017
View articletitled, Combination Therapy Targeting BCL6 and Phospho-STAT3 Defeats Intratumor Heterogeneity in a Subset of Non–Small Cell Lung Cancers
Open the PDF for Combination Therapy Targeting BCL6 and Phospho-STAT3 Defeats Intratumor Heterogeneity in a Subset of Non–Small Cell Lung Cancers in another window
Includes: Supplementary data
Journal Articles

PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis

Free
Xiaorong Zhou, Barrett L. Updegraff, Yabin Guo, Michael Peyton, Luc Girard, Jill E. Larsen, Xian-Jin Xie, Yunyun Zhou, Tae Hyun Hwang, Yang Xie, Jaime Rodriguez-Canales, Pamela Villalobos, Carmen Behrens, Ignacio I. Wistuba, John D. Minna, Kathryn A. O'Donnell
Journal: Cancer Research
Cancer Res (2017) 77 (1): 187–197.
https://doi.org/10.1158/0008-5472.CAN-16-1267-T
Published: 02 January 2017
View articletitled, PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis
Open the PDF for PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

Abstract 5170: Snail-dependent ESRP1 silencing drives malignant conversion of human pulmonary epithelial cells

Free
Tonya C. Walser, Zhe Jing, Linh Tran, Ying Lin, Li Zhu, Sherven Sharma, Aik Ooi, Brigitte N. Gomperts, Jerry W. Shay, Jill E. Larsen, Boning Gao, John D. Minna, Micihael C. Fishbein, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 5170.
https://doi.org/10.1158/1538-7445.AM2016-5170
Published: 15 July 2016
View articletitled, Abstract 5170: Snail-dependent ESRP1 silencing drives malignant conversion of human pulmonary epithelial cells
Journal Articles

Abstract 932: The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation

Free
Stacy J. Park, Tonya C. Walser, Catalina Perdomo, Teresa Wang, Long-Sheng Hong, Paul C. Pagano, Elvira L. Liclican, Kostyantyn Krysan, Jill E. Larsen, Michael C. Fishbein, John D. Minna, Marc E. Lenburg, Avrum Spira, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 932.
https://doi.org/10.1158/1538-7445.AM2014-932
Published: 01 October 2014
View articletitled, Abstract 932: The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation
Journal Articles

Abstract 1525: Exome sequencing to identify permissive mutations representing acquired vulnerabilities in lung cancer

Free
Jill E. Larsen, Caleb F. Davis, Kenneth Huffman, Luc Girard, David A. Wheeler, Richard A. Gibbs, John D. Minna
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1525.
https://doi.org/10.1158/1538-7445.AM2014-1525
Published: 01 October 2014
View articletitled, Abstract 1525: Exome sequencing to identify permissive mutations representing acquired vulnerabilities in lung cancer
Journal Articles

Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer

Free
Hyun Seok Kim, Saurabh Mendiratta, Jiyeon Kim, Chad Victor Pecot, Jill E. Larsen, Iryna Zubovych, Bo Yeun Seo, Jimi Kim, Banu Eskiocak, Hannah Chung, Elizabeth McMillan, Sherry Wu, Jef De Brabander, Kakajan Komurov, Bruce A. Posner, Rolf Brekken, Anil K. Sood, Ralph J. Deberardinis, Michael G. Roth, John D. Minna, Michael A. White
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C16.
https://doi.org/10.1158/1538-7445.FBCR13-C16
Published: 15 May 2014
View articletitled, Abstract C16: Mapping synthetic vulnerabilities in non-small cell lung cancer
Journal Articles

Abstract 2558: VEGF-dependent suppression of prostaglandin transporter (PGT) expression in Kras mutant human bronchial epithelial cells

Free
Gina Lee, Brian K. Gardner, Saswati Hazra, Puja Kachroo, Mi-Heon Lee, Kostyantyn Krysan, Tonya C. Walser, Jill E. Larsen, Luc Girard, Ignacio I. Wistuba, John D. Minna, Steven M. Dubinett
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2558.
https://doi.org/10.1158/1538-7445.AM2012-2558
Published: 15 April 2012
View articletitled, Abstract 2558: VEGF-dependent suppression of prostaglandin transporter (PGT) expression in Kras mutant human bronchial epithelial cells
Journal Articles

SMAC Mimetic (JP1201) Sensitizes Non–Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF-α–Independent Manner

Free
Rachel M. Greer, Michael Peyton, Jill E. Larsen, Luc Girard, Yang Xie, Adi F. Gazdar, Patrick Harran, Lai Wang, Rolf A. Brekken, Xiaodong Wang, John D. Minna
Journal: Cancer Research
Cancer Res (2011) 71 (24): 7640–7648.
https://doi.org/10.1158/0008-5472.CAN-10-3947
Published: 15 December 2011
View articletitled, SMAC Mimetic (JP1201) Sensitizes Non–Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF-α–Independent Manner
Open the PDF for SMAC Mimetic (JP1201) Sensitizes Non–Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF-α–Independent Manner in another window
Includes: Supplementary data
Journal Articles

Abstract 3419: Defining the role of ZEB1 in the molecular pathogenesis of lung cancer

Free
Jill E. Larsen, Mitsuo Sato, James P. Sullivan, Luc Girard, Jerry W. Shay, John D. Minna
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3419.
https://doi.org/10.1158/1538-7445.AM2011-3419
Published: 15 April 2011
View articletitled, Abstract 3419: Defining the role of ZEB1 in the molecular pathogenesis of lung cancer
Journal Articles

Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling

Free
James P. Sullivan, Monica Spinola, Michael Dodge, Maria G. Raso, Carmen Behrens, Boning Gao, Katja Schuster, Chunli Shao, Jill E. Larsen, Laura A. Sullivan, Sofia Honorio, Yang Xie, Pier P. Scaglioni, J. Michael DiMaio, Adi F. Gazdar, Jerry W. Shay, Ignacio I. Wistuba, John D. Minna
Journal: Cancer Research
Cancer Res (2010) 70 (23): 9937–9948.
https://doi.org/10.1158/0008-5472.CAN-10-0881
Published: 06 December 2010
View articletitled, Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
Open the PDF for Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 2211: Array-comparative genomic hybridization identifies important recurrent copy number alterations in non-small cell lung cancer

Free
Bajee K. Sriram, Jill E. Larsen, Santiyagu M. Savarimuthu Francis, Casey M. Wright, Belinda E. Clarke, Edwina E. Duhig, Hayward K. N, Rayleen V. Bowman, Ian A. Yang, Kwun M. Fong
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2211.
https://doi.org/10.1158/1538-7445.AM10-2211
Published: 15 April 2010
View articletitled, Abstract 2211: Array-comparative genomic hybridization identifies important recurrent copy number alterations in non-small cell lung cancer
Journal Articles

Abstract 2362: Defining the role of ZEB1 in the molecular pathogenesis of lung cancer

Free
Jill E. Larsen, Mitsuo Sato, James P. Sullivan, Luc Girard, Yang Xie, Jerry W. Shay, John D. Minna
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2362.
https://doi.org/10.1158/1538-7445.AM10-2362
Published: 15 April 2010
View articletitled, Abstract 2362: Defining the role of ZEB1 in the molecular pathogenesis of lung cancer