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Jie Zhang
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Journal Articles

Abstract PO1-16-09: Does T1c-2N0-1M0 triple negative breast cancer derive a benefit from neoadjuvant chemotherapy?

Jie Zhang, Yushuai Yu, Weiwei Chen, Wenfen Fu, Ruiliang Chen, Jialu Yi, Chuangui Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-16-09.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-16-09
Published: 02 May 2024
View article titled, Abstract PO1-16-09: Does T1c-2N0-1M0 triple negative breast cancer derive a benefit from neoadjuvant chemotherapy?
Journal Articles

Abstract PO5-24-10: Clinical significance and immune landscape analyses of the immune related genes based prognostic signature for HER2 positive breast cancer

Xiaofen Li, Wenfen Fu, Yushuai Yu, Jie Zhang, Chuangui Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-24-10.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-24-10
Published: 02 May 2024
View article titled, Abstract PO5-24-10: Clinical significance and immune landscape analyses of the immune related genes based prognostic signature for HER2 positive breast cancer
Journal Articles

Abstract PO4-23-04: Is breast-conserving surgery an optional local therapy for non-inflammatory skin involvement (T4b) breast cancer? A Propensity Score Matching and Inverse Probability Weighting Analysis of SEER Database Results

Jingyi Lin, Shiping Luo, Jie Zhang, Chuangui Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-23-04.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-23-04
Published: 02 May 2024
View article titled, Abstract PO4-23-04: Is breast-conserving surgery an optional local therapy for non-inflammatory skin involvement (T4b) breast cancer? A Propensity Score Matching and Inverse Probability Weighting Analysis of SEER Database Results
Journal Articles

Abstract PO3-07-07: Predictive Modeling for Identifying Breast Cancer Patients Eligible for Axillary Lymph Node Dissection Exemption Following Neoadjuvant Therapy: A Longitudinal MRI-based Radiomics and Deep Learning Features Analysis

Yushuai Yu, Jialu Yi, Ruiliang Chen, Kaiyan Huang, Jie Zhang, Chuangui Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-07-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-07-07
Published: 02 May 2024
View article titled, Abstract PO3-07-07: Predictive Modeling for Identifying Breast Cancer Patients Eligible for Axillary Lymph Node Dissection Exemption Following Neoadjuvant Therapy: A Longitudinal MRI-based Radiomics and Deep Learning Features Analysis
Journal Articles

Abstract PO1-14-03: Discovery of proliferation essential gene signature and ACTL6A as potential biomarker for predicting prognosis and neoadjuvant therapy response in triple-positive breast cancer

Xiaofen Li, Wenfen Fu, Shiping Luo, Jie Zhang, Qingshui Wang, Chuangui Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-14-03.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-14-03
Published: 02 May 2024
View article titled, Abstract PO1-14-03: Discovery of proliferation essential gene signature and ACTL6A as potential biomarker for predicting prognosis and neoadjuvant therapy response in triple-positive breast cancer
Journal Articles

Abstract PO2-04-07: Efficacy and Safety of First-line Therapy in Patients with HER-2 positive Advanced Breast Cancer:A network Meta-analysis of Randomized Controlled Trials

Junxiao Wang, Yushuai Yu, Jie Zhang, Chuangui Song
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-04-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-04-07
Published: 02 May 2024
View article titled, Abstract PO2-04-07: Efficacy and Safety of First-line Therapy in Patients with HER-2 positive Advanced Breast Cancer:A network Meta-analysis of Randomized Controlled Trials
Journal Articles

Abstract LB077: CSF-1R inhibition with Pimicotinib (ABSK021) enhanced anti-tumor efficacy of KRASG12C inhibitors in preclinical non-small cell lung cancer mouse models

Nannan Zhang, Bin Shen, Shenyan Liu, Cheng Dai, Haiyan Ying, Fushen Guo, Zhixuan Zhu, Wan Shi, Min Tu, Jie Wang, Jie Zhang, Manqi Liu, Qi Zhang, Zhui Chen
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB077.
https://doi.org/10.1158/1538-7445.AM2024-LB077
Published: 05 April 2024
View article titled, Abstract LB077: CSF-1R inhibition with Pimicotinib (ABSK021) enhanced anti-tumor efficacy of KRASG12C inhibitors in preclinical non-small cell lung cancer mouse models
Journal Articles

Abstract 1228: Selective FGFR4 inhibitor Irpagratinib (ABSK011) exhibits broad synergistic and combinatory anti-tumor effects with other therapeutic agents in preclinical HCC models

Nannan Zhang, Bin Shen, Zhidong He, Cheng Dai, Jie Wang, Jie Zhang, Manqi Liu, Yongxian Zhang, Zhui Chen
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1228.
https://doi.org/10.1158/1538-7445.AM2024-1228
Published: 22 March 2024
View article titled, Abstract 1228: Selective FGFR4 inhibitor Irpagratinib (ABSK011) exhibits broad synergistic and combinatory anti-tumor effects with other therapeutic agents in preclinical HCC models
Journal Articles

Abstract 5727: ISM9682A, a novel and potent KIF18A inhibitor, shows robust antitumor effects against chromosomally unstable cancers

Jie Zhang, Feng Gao, Wei Zhu, Chenxi Xu, Xiaoyu Ding, Jing Shang, Junwen Qiao, Shan Chen, Xin Cai, Xiao Ding, Supriya Bavadekar, Sujata Rao, Man Zhang, Feng Ren, Alex Zhavoronkov
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5727.
https://doi.org/10.1158/1538-7445.AM2024-5727
Published: 22 March 2024
View article titled, Abstract 5727: ISM9682A, a novel and potent KIF18A inhibitor, shows robust antitumor effects against chromosomally unstable cancers
Journal Articles

Abstract 257: Plasticity of preneoplastic cells drives esophageal squamous cell cancer initiation

Kyung Pil Ko, Jie Zhang, Sohee Jun, Jae-Il Park
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 257.
https://doi.org/10.1158/1538-7445.AM2024-257
Published: 22 March 2024
View article titled, Abstract 257: Plasticity of preneoplastic cells drives esophageal squamous cell cancer initiation
Journal Articles

Fasting-Mimicking Diet Drives Antitumor Immunity against Colorectal Cancer by Reducing IgA-Producing Cells

Ziwen Zhong, Hao Zhang, Ke Nan, Jing Zhong, Qichao Wu, Lihong Lu, Ying Yue, Zhenyu Zhang, Miaomiao Guo, Zhiqiang Wang, Jie Xia, Yun Xing, Ying Fu, Baichao Yu, Wenchang Zhou, Xingfeng Sun, Yang Shen, Wankun Chen, Jie Zhang, Jin Zhang, Duan Ma, Yiwei Chu, Ronghua Liu, Changhong Miao
Journal: Cancer Research
Cancer Res (2023) 83 (21): 3529–3543.
https://doi.org/10.1158/0008-5472.CAN-23-0323
Published: 01 November 2023
View article titled, Fasting-Mimicking Diet Drives Antitumor Immunity against Colorectal Cancer by Reducing IgA-Producing Cells
Open the PDF for Fasting-Mimicking Diet Drives Antitumor Immunity against Colorectal Cancer by Reducing IgA-Producing Cells in another window
Includes: Supplementary data
Journal Articles

Abstract CT049: VELOCITY-Lung: A phase 2 study evaluating safety and efficacy of sacituzumab govitecan (SG) + zimberelimab (zim) + etrumadenant (etruma) in patients (pts) with advanced or metastatic non-small cell lung cancer (mNSCLC) progressing on or after platinum (PT)-based chemotherapy and checkpoint inhibitors (CPI)

Anjali Rohatgi, James Chih-Hsin Yang, Dong-Wan Kim, Molly Li, Joseph Park, Anna Seto, Jie Zhang, Nir Peled
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT049.
https://doi.org/10.1158/1538-7445.AM2023-CT049
Published: 14 April 2023
View article titled, Abstract CT049: VELOCITY-Lung: A phase 2 study evaluating safety and efficacy of sacituzumab govitecan (SG) + zimberelimab (zim) + etrumadenant (etruma) in patients (pts) with advanced or metastatic non-small cell lung cancer (mNSCLC) progressing on or after platinum (PT)-based chemotherapy and checkpoint inhibitors (CPI)
Journal Articles

Abstract LB329: A potent and selective small molecule inhibitor of CSF-1R ABSK021 demonstrates strong efficacy in preclinical models of osteosarcoma

Nannan Zhang, Cheng Dai, Jiacheng Zhang, Shuqun Yang, Jie Wang, Jie Zhang, Manqi Liu, Zhui Chen
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB329.
https://doi.org/10.1158/1538-7445.AM2023-LB329
Published: 14 April 2023
View article titled, Abstract LB329: A potent and selective small molecule inhibitor of CSF-1R ABSK021 demonstrates strong efficacy in preclinical models of osteosarcoma
Journal Articles

Abstract LB316: A next-generation KRASG12C inhibitor ABSK071 demonstrated broad synergy with other therapeutic agents in KRASG12C mutated cancer models

Haiyan Ying, Fushen Guo, Juan Peng, Jie Wang, Jie Zhang, Manqi Liu, Zhixuan Zhu, Zhui Chen
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB316.
https://doi.org/10.1158/1538-7445.AM2023-LB316
Published: 14 April 2023
View article titled, Abstract LB316: A next-generation KRAS<sup>G12C</sup> inhibitor ABSK071 demonstrated broad synergy with other therapeutic agents in KRAS<sup>G12C</sup> mutated cancer models
Journal Articles

Abstract 245: Development of a novel urine cell-free DNA preservation method for molecular profiling in genitourinary tumors

jie zhang, fang liu, min wang, cuishan deng, wei mo, seng tao, amy wang, shidong jia, zhixin zhao, pan du, binggang xiang, shujun luo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 245.
https://doi.org/10.1158/1538-7445.AM2023-245
Published: 04 April 2023
View article titled, Abstract 245: Development of a novel urine cell-free DNA preservation method for molecular profiling in genitourinary tumors
Journal Articles

Abstract 1714: CRACD/KIAA1211 loss drives cell plasticity and immune evasion of small cell lung cancer

Shengzhe Zhang, Kee-Bum Kim, Yuanjian Huang, Dong-Wook Kim, Bongjun Kim, Kyung-Pil Ko, Gengyi Zou, Jie Zhang, Sohee Jun, Nicole A. Kirk, Ye Eun Hwang, Young Ho Ban, Joseph M. Chan, Charles M. Rudin, Kwon-Sik Park, Jae-Il Park
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1714.
https://doi.org/10.1158/1538-7445.AM2023-1714
Published: 04 April 2023
View article titled, Abstract 1714: <em>CRACD/KIAA1211</em> loss drives cell plasticity and immune evasion of small cell lung cancer
Journal Articles

Abstract 6337: Tri-specific CD3 x HER2 x HER2 antibodies in 1:2 format recognizing two different epitopes on HER2 demonstrate selective activity on human cancer cells with high HER2 expression

Jie Zhang, Xiaoqing Wang, Zhenhao Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6337.
https://doi.org/10.1158/1538-7445.AM2023-6337
Published: 04 April 2023
View article titled, Abstract 6337: Tri-specific CD3 x HER2 x HER2 antibodies in 1:2 format recognizing two different epitopes on HER2 demonstrate selective activity on human cancer cells with high HER2 expression
Journal Articles

CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2

Haoyan Li, Yin Wang, Kevin Lin, Varadha Balaji Venkadakrishnan, Martin Bakht, Wei Shi, Chenling Meng, Jie Zhang, Kaitlyn Tremble, Xin Liang, Jian H. Song, Xu Feng, Vivien Van, Pingna Deng, Jared K. Burks, Ana Aparicio, Khandan Keyomarsi, Junjie Chen, Yue Lu, Himisha Beltran, Di Zhao
Journal: Cancer Research
Cancer Res (2022) 82 (17): 3088–3101.
https://doi.org/10.1158/0008-5472.CAN-22-0631
Published: 02 September 2022
View article titled, CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2
Open the PDF for CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2 in another window
Includes: Supplementary data
Journal Articles

Abstract 1446: Genetic risk factors for the development of multiple primary cancers

Jovia L. Nierenberg, Linda Kachuri, Taylor B. Cavazos, Rebecca E. Graff, Thomas J. Hoffmann, Jie Zhang, Stacey Alexeeff, Laurel Habel, Douglas Corley, Stephen Van Den Eeden, Elad Ziv, Lori C. Sakoda, John S. Witte
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1446.
https://doi.org/10.1158/1538-7445.AM2022-1446
Published: 15 June 2022
View article titled, Abstract 1446: Genetic risk factors for the development of multiple primary cancers
Journal Articles

Abstract 3143: RIG-I agonism promotes immune activation in syngeneic tumor model

Mark Zielstorff, Yiping Chen, Jeremy Presland, Alan Byford, Amy Doty, Erik Munsell, Craig Parish, Gretchen Baltus, Lily Moy, George Addona, Jie Zhang-Hoover
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3143.
https://doi.org/10.1158/1538-7445.AM2022-3143
Published: 15 June 2022
View article titled, Abstract 3143: RIG-I agonism promotes immune activation in syngeneic tumor model