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Jianjun Yu
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Journal Articles

Abstract P2-07-01: Blood tumor mutational burden (bTMB) and blood copy number burden (bCNB) by genome-wide circulating tumor DNA (ctDNA) assessment predict outcome and resistance in hormone-receptor positive (HR+), HER2 negative (HER2-) metastatic breast cancer (MBC) patients (pts) treated with CDK4/6 inhibitor (CDK4/6i)

Andrew Davis, Jingqin Luo, Tiantian Zheng, Lu Tan, Amy Wang, Rama Suresh, Foluso Ademuyiwa, Caron Rigden, Timothy Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Pavan K Tandra, Tracy Summa, Brittney Haas, Shana Thomas, Leonel Hernandez-Aya, Lindsay Peterson, Shujun Luo, Bonnie L King, Shidong Jia, Jianjun Yu, Pan Du, Jairam Krishnamurthy, Cynthia X Ma, C Dai
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-07-01.
https://doi.org/10.1158/1538-7445.SABCS21-P2-07-01
Published: 15 February 2022
View articletitled, Abstract P2-07-01: Blood tumor mutational burden (bTMB) and blood copy number burden (bCNB) by genome-wide circulating tumor DNA (ctDNA) assessment predict outcome and resistance in hormone-receptor positive (HR+), HER2 negative (HER2-) metastatic breast cancer (MBC) patients (pts) treated with CDK4/6 inhibitor (CDK4/6i)
Journal Articles

Abstract 551: Clinical utility of cell-free DNA based PTEN copy number loss in prostate cancer

Xiaoxi Dong, Minghua Zhang, Tiantian Zheng, Lu Tan, Feng Xie, Amy Xiaohong Wang, Pan Du, Shidong Jia, Chris Lu, Jianjun Yu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 551.
https://doi.org/10.1158/1538-7445.AM2021-551
Published: 01 July 2021
View articletitled, Abstract 551: Clinical utility of cell-free DNA based PTEN copy number loss in prostate cancer
Journal Articles

Abstract PS16-08: Germline mutation landscape in Chinese breast cancer patients

Nan Wang, Jiayang Zhang, Lu Tan, Hao Liao, Yaxin Liu, Xinyu Gui, Jiaxin Niu, Feng Xie, Yue Zhang, Yong Huang, Jianjun Yu, Huiping Li
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS16-08.
https://doi.org/10.1158/1538-7445.SABCS20-PS16-08
Published: 15 February 2021
View articletitled, Abstract PS16-08: Germline mutation landscape in Chinese breast cancer patients
Journal Articles

Abstract 3108: Combined cfDNA and cfRNA NGS testing for cancer patient care

Yong Huang, Yue Zhang, Binggang Xiang, Zhixin Zhao, Xiaohong Wang, Feng Xie, Reza Moktari, Kemin Zhou, Pan Du, Shidong Jia, Jianjun Yu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3108.
https://doi.org/10.1158/1538-7445.AM2020-3108
Published: 15 August 2020
View articletitled, Abstract 3108: Combined cfDNA and cfRNA NGS testing for cancer patient care
Journal Articles

Abstract 3098: Urine-based molecular biomarker signatures for bladder cancer

Zhixin Zhao, Amy Chang, Binggang Xiang, Feng Xie, Xiaohong Wang, Kemin Zhou, Jianjun Yu, Pan Du, Shidong Jia
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3098.
https://doi.org/10.1158/1538-7445.AM2020-3098
Published: 15 August 2020
View articletitled, Abstract 3098: Urine-based molecular biomarker signatures for bladder cancer
Journal Articles

Abstract 3670: Development of cfDNA-based methylation assay for early cancer detections

Binggang Xiang, Zhixin Zhao, Maya Stevens, Chao Dai, Feng Xie, Xiaohong Wang, Kemin Zhou, Shidong Jia, Pan Du, Jianjun Yu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3670.
https://doi.org/10.1158/1538-7445.AM2020-3670
Published: 15 August 2020
View articletitled, Abstract 3670: Development of cfDNA-based methylation assay for early cancer detections
Journal Articles

Abstract P5-01-10: Next generation sequencing-based gene variant-oriented characterization in metastatic breast cancer: An innovative analysis using ctDNA

Lorenzo Gerratana, Qiang Zhang, Ami N Shah, Alessandra Franzoni, Jianjun Yu, Shidong Jia, Andrew A Davis, Youbin Zhang, Firas Wehbe, Amir Behdad, Leonidas C Platanias, William J Gradishar, Massimo Cristofanilli
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P5-01-10.
https://doi.org/10.1158/1538-7445.SABCS19-P5-01-10
Published: 15 February 2020
View articletitled, Abstract P5-01-10: Next generation sequencing-based gene variant-oriented characterization in metastatic breast cancer: An innovative analysis using ctDNA
Journal Articles

Abstract P2-11-09: Characterization of metastatic breast cancer through a novel next generation sequencing platform for hypothesis generation on endocrine resistance

Lorenzo Gerratana, Qiang Zhang, Andrew A Davis, Ami N Shah, Jianjun Yu, Shidong Jia, Youbin Zhang, Firas Wehbe, Amir Behdad, Leonidas C Platanias, William J Gradishar, Massimo Cristofanilli
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): P2-11-09.
https://doi.org/10.1158/1538-7445.SABCS19-P2-11-09
Published: 15 February 2020
View articletitled, Abstract P2-11-09: Characterization of metastatic breast cancer through a novel next generation sequencing platform for hypothesis generation on endocrine resistance
Journal Articles

Abstract 425: Development and validation of liquid biopsy assay for copy number loss in cancers

Simo Zhang, Feng Xie, Amy Chang, Zhixin Zhao, Carlos Montesinos, Xiaohong Wang, Kemin Zhou, Shidong Jia, Jianjun Yu, Pan Du
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 425.
https://doi.org/10.1158/1538-7445.AM2019-425
Published: 01 July 2019
View articletitled, Abstract 425: Development and validation of liquid biopsy assay for copy number loss in cancers
Journal Articles

Abstract 2214: Development and validation of PredicineATLAS, a 600-gene liquid biopsy panel for simultaneous detection of TMB and genomic alterations in Immuno-Oncology

Zhixin Zhao, Amy Chang, Tak Cheung, Feng Xie, Carlos Montesinos, Amy Xiaohong Wang, Kemin Zhou, Shidong Jia, JIanjun Yu, Pan Du
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2214.
https://doi.org/10.1158/1538-7445.AM2019-2214
Published: 01 July 2019
View articletitled, Abstract 2214: Development and validation of PredicineATLAS, a 600-gene liquid biopsy panel for simultaneous detection of TMB and genomic alterations in Immuno-Oncology
Journal Articles

Abstract 1385: Prognostic and predictive utility of copy number variations (CNVs) in circulating tumor DNA (ctDNA) from metastatic castration-resistant prostate cancer (mCRPC) patients

Heidi Fettke, Edmond M. Kwan, Jianjun Yu, Amy Wang, Carlos Montesinos, Calvin Wong, Xue Gong, Tiantian Zheng, Peter Pan Du, Shidong Jia, Andrew Mant, Phillip Parente, Carmel Pezaro, Arun A. Azad
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1385.
https://doi.org/10.1158/1538-7445.AM2019-1385
Published: 01 July 2019
View articletitled, Abstract 1385: Prognostic and predictive utility of copy number variations (CNVs) in circulating tumor DNA (ctDNA) from metastatic castration-resistant prostate cancer (mCRPC) patients
Journal Articles

Abstract 4893: Combined immunohistochemistry and NGS-based patient profiling for predicting anti-PD-1/PD-L1 therapy response

Jianjun Yu, Jianguo Dong, Amy Wang, Joseph S. Krueger
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4893.
https://doi.org/10.1158/1538-7445.AM2019-4893
Published: 01 July 2019
View articletitled, Abstract 4893: Combined immunohistochemistry and NGS-based patient profiling for predicting anti-PD-1/PD-L1 therapy response
Journal Articles

Abstract 5570: Analytical and clinical validation of blood-based NGS panel for detection of genomic alterations in DNA repair pathways

Xiaohong Wang, Jianjun Yu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5570.
https://doi.org/10.1158/1538-7445.AM2018-5570
Published: 01 July 2018
View articletitled, Abstract 5570: Analytical and clinical validation of blood-based NGS panel for detection of genomic alterations in DNA repair pathways
Journal Articles

Abstract 3659: Detection and validation of cancer immunotherapy biomarkers in blood

Feng Xie, Jianjun Yu, Shidong Jia
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3659.
https://doi.org/10.1158/1538-7445.AM2018-3659
Published: 01 July 2018
View articletitled, Abstract 3659: Detection and validation of cancer immunotherapy biomarkers in blood
Journal Articles

Abstract 3670: Urine- and blood-based DNA+RNA liquid biopsy tests in prostate, bladder and kidney cancers

Amy Wang, Zhixin Zhao, Cheng Xie, Tak Cheung, Carlos Montesinos, Phoebe Zhang, Pan Du, Jianjun Yu, Shidong Jia
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3670.
https://doi.org/10.1158/1538-7445.AM2018-3670
Published: 01 July 2018
View articletitled, Abstract 3670: Urine- and blood-based DNA+RNA liquid biopsy tests in prostate, bladder and kidney cancers
Journal Articles

Abstract 2909: A gene signature composed of 13 p53 target genes predicts for response to NVP-CGM097, a novel p53-Mdm2 inhibitor, in cell lines and in human primary tumor xenograft models

Sebastien Jeay, Swann Gaulis, Stéphane Ferretti, Geneviève Albrecht, Louise Barys, Daniel Guthy, Ensar Halilovic, Moriko Ito, Masato Murakami, Astrid Pornon, Stephan Ruetz, Kavitha Venkatesan, Jianjun Yu, Michael Jensen, Marion Wiesmann, Jens Wuerthner, Diana Graus-Porta
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2909.
https://doi.org/10.1158/1538-7445.AM2014-2909
Published: 01 October 2014
View articletitled, Abstract 2909: A gene signature composed of 13 p53 target genes predicts for response to NVP-CGM097, a novel p53-Mdm2 inhibitor, in cell lines and in human primary tumor xenograft models
Journal Articles

Abstract IA19: Cooperation between androgen receptor and Polycomb in prostate cancer

Jonathan C. Zhao, Christine Runkle, Jianjun Yu, Longtao Wu, Hongjian Jin, Timothy Kuzel, Chung Lee, Jindan Yu
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): IA19.
https://doi.org/10.1158/1538-7445.PRCA2012-IA19
Published: 09 May 2013
View articletitled, Abstract IA19: Cooperation between androgen receptor and Polycomb in prostate cancer
Journal Articles

Abstract 5194: Pim2 is required for maintaining Multiple Myeloma cell proliferation through modulating mTORC1 pathway.

Jing Lu, Tatiana Zavorotinskaya, Yumin Dai, Xiaohong Niu, Joseph Castillo, Janet Sim, Jianjun Yu, Kevin Shannon, Pablo Garcia
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5194.
https://doi.org/10.1158/1538-7445.AM2013-5194
Published: 15 April 2013
View articletitled, Abstract 5194: Pim2 is required for maintaining Multiple Myeloma cell proliferation through modulating mTORC1 pathway.
Journal Articles

Abstract #4243: An integrated network of androgen receptor and TMPRSS2-ERG gene fusions in prostate cancer

Jindan Yu, Jianjun Yu, Ram Mani, Adaikkalam Vellaichamy, Qi Cao, Bharathi Laxman, James Li, Xuhong Cao, Terrence Barrette, Zhaohui Qin, Sooryanarayana Varambally, Arul Chinnaiyan
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4243.
Published: 01 May 2009
View articletitled, Abstract #4243: An integrated network of androgen receptor and TMPRSS2-ERG gene fusions in prostate cancer
Journal Articles

Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer

Rohit Mehra, Scott A. Tomlins, Jianjun Yu, Xuhong Cao, Lei Wang, Anjana Menon, Mark A. Rubin, Kenneth J. Pienta, Rajal B. Shah, Arul M. Chinnaiyan
Journal: Cancer Research
Cancer Res (2008) 68 (10): 3584–3590.
https://doi.org/10.1158/0008-5472.CAN-07-6154
Published: 15 May 2008
View articletitled, Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer
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Includes: Supplementary data