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Jian Zhu
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Journal Articles

Abstract 5329: Development of a novel selective CDK4 inhibitor for HR+/HER2- breast cancer

Free
Mei Hua Li, Apeng Liang, Kai Wang, Yi Long, Rui Wu, Hui Xu, Jian Zhu, Guangbin Liu, Ling Fang, Xi Wang, Chenjie Pan, Yiming Cai, Xiang Zhang, Shengli Dong, Yu Yu, Xinlong Yang, Chao Zhou, Wei Wu, Chengshan Niu, Mingyu Jiang, Shaoqing Chen, Jun Li, Yusheng Wu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5329.
https://doi.org/10.1158/1538-7445.AM2025-5329
Published: 21 April 2025
View articletitled, Abstract 5329: Development of a novel selective CDK4 inhibitor for HR+/HER2- breast cancer
Journal Articles

Abstract 821: A potent CDK7 inhibitor TY-2699a suppresses palbociclib-resistant breast cancer and has the potential for combination with chemotherapy or immunotherapy in solid tumors

Free
Shengli Dong, Apeng Liang, Shaoqing Chen, Zhengfei Guo, Jian Zhu, Huan Wang, Jing-Lan Mu, Yakun Qi, Meihua Li, Kai Wang, Hongqiang Li, Xinlong Yang, Chao Zhou, Zhiyong He, Zhengzhou, Henan Niu, Mingyu Jiang, Xiugui Chen, Jun Li, Yusheng Wu
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 821.
https://doi.org/10.1158/1538-7445.AM2025-821
Published: 21 April 2025
View articletitled, Abstract 821: A potent CDK7 inhibitor TY-2699a suppresses palbociclib-resistant breast cancer and has the potential for combination with chemotherapy or immunotherapy in solid tumors
Journal Articles

Abstract 5981: TY-2699a is a highly potent CDK7 inhibitor to abolish dysfunctional tumor cell cycle for clinical development

Free
Shengli Dong, Apeng Liang, Jian Zhu, Huan Wang, Meihua Li, Kai Wang, Rongzhen Ni, Haoyun Li, Yundi Cao, Linglin Xiao, Hongqiang Li, Yian Tu, Chao Zhou, Aishen Gong, Shuyi Xu, Hui Su, Chengshan Niu, Mingyu Jiang, Feng Xing, Xiugui Chen, Shaoqing Chen, Jun Li, Yusheng Wu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5981.
https://doi.org/10.1158/1538-7445.AM2023-5981
Published: 04 April 2023
View articletitled, Abstract 5981: TY-2699a is a highly potent CDK7 inhibitor to abolish dysfunctional tumor cell cycle for clinical development
Journal Articles

Abstract 6565: Impact of TIM-3 modulation on the sensitivity of anti-PD-1

Free
Jian Zhu, Rebecca L. Zhu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 6565.
https://doi.org/10.1158/1538-7445.AM2020-6565
Published: 15 August 2020
View articletitled, Abstract 6565: Impact of TIM-3 modulation on the sensitivity of anti-PD-1
Journal Articles

Abstract 673: Impact of PD-L1 feedback modulation on the sensitivity of anti-PD-1/PD-L1

Free
Jian Zhu, Rebecca L. Zhu
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 673.
https://doi.org/10.1158/1538-7445.AM2019-673
Published: 01 July 2019
View articletitled, Abstract 673: Impact of PD-L1 feedback modulation on the sensitivity of anti-PD-1/PD-L1
Journal Articles

Abstract A30: Drug-gene-microRNA networks in therapeutic and biomarker development

Free
Jian Zhu
Journal: Cancer Research
Cancer Res (2012) 72 (13_Supplement): A30.
https://doi.org/10.1158/1538-7445.CSB12-A30
Published: 06 November 2014
View articletitled, Abstract A30: Drug-gene-microRNA networks in therapeutic and biomarker development
Journal Articles

SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer

Free
Nicholas I. Fleming, Robert N. Jorissen, Dmitri Mouradov, Michael Christie, Anuratha Sakthianandeswaren, Michelle Palmieri, Fiona Day, Shan Li, Cary Tsui, Lara Lipton, Jayesh Desai, Ian T. Jones, Stephen McLaughlin, Robyn L. Ward, Nicholas J. Hawkins, Andrew R. Ruszkiewicz, James Moore, Hong-Jian Zhu, John M. Mariadason, Antony W. Burgess, Dana Busam, Qi Zhao, Robert L. Strausberg, Peter Gibbs, Oliver M. Sieber
Journal: Cancer Research
Cancer Res (2013) 73 (2): 725–735.
https://doi.org/10.1158/0008-5472.CAN-12-2706
Published: 16 January 2013
View articletitled, SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer
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Includes: Supplementary data
Journal Articles

Abstract LB-100: Computational assessment of oncogenic pathways modulated by vorinostat in breast cancer stem cells

Free
Jian Zhu, Hsiu-Fang Lee, Hasan Korkaya, Suling Liu, Sean McDemott, Max S. Wicha, Duxin Sun
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-100.
https://doi.org/10.1158/1538-7445.AM2012-LB-100
Published: 15 April 2012
View articletitled, Abstract LB-100: Computational assessment of oncogenic pathways modulated by vorinostat in breast cancer stem cells
Journal Articles

Epothilones, a New Class of Microtubule-stabilizing Agents with a Taxol-like Mechanism of Action

Free
Daniel M. Bollag, Patricia A. McQueney, Jian Zhu, Otto Hensens, Lawrence Koupal, Jerrold Liesch, Michael Goetz, Elias Lazarides, Catherine M. Woods
Journal: Cancer Research
Cancer Res (1995) 55 (11): 2325–2333.
Published: 01 June 1995
View articletitled, Epothilones, a New Class of Microtubule-stabilizing Agents with a Taxol-like Mechanism of Action
Open the PDF for Epothilones, a New Class of Microtubule-stabilizing Agents with a Taxol-like Mechanism of Action in another window