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Journal Articles

mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma

Shanshan Zhang, Yu-Feng Zhou, Jian Cao, Stephen K. Burley, Hui-Yun Wang, X.F. Steven Zheng
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5652–5665.
https://doi.org/10.1158/0008-5472.CAN-21-0206
Published: 15 November 2021
View article titled, mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma
Open the PDF for mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition

Molly Gale, Yao Li, Jian Cao, Zongzhi Z. Liu, Marissa A. Holmbeck, Meiling Zhang, Sabine M. Lang, Lizhen Wu, Mariana Do Carmo, Swati Gupta, Keisuke Aoshima, Michael P. DiGiovanna, David F. Stern, David L. Rimm, Gerald S. Shadel, Xiang Chen, Qin Yan
Journal: Cancer Research
Cancer Res (2020) 80 (3): 524–535.
https://doi.org/10.1158/0008-5472.CAN-18-3985
Published: 03 February 2020
View article titled, Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition
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Includes: Supplementary data
Journal Articles

Abstract 3897: A novel c-Met targeting antibody drug conjugate for NSCLC

Lingna Li, Cathrine Fells, Julia Guo, Pia Muyot, Edwige Gros, Yanliang Zhang, Yingqing Sun, Hong Zhang, Yanwen Fu, Tong Zhu, Jian Cao, Gunnar Kaufmann, Gang Chen, Zhenwei Miao
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3897.
https://doi.org/10.1158/1538-7445.AM2016-3897
Published: 15 July 2016
View article titled, Abstract 3897: A novel c-Met targeting antibody drug conjugate for NSCLC
Journal Articles

Abstract LB-002: A novel c-Met/EGFR bispecific targeting antibody drug conjugate for NSCLC

Gang Chen, Lingna Li, Pia Muyot, Edwige Gros, Yanliang Zhang, Yingqing Sun, Hong Zhang, Yanwen Fu, Alice Lee, Jian Cao, Gunnar Kaufmann, Zhenwei Miao
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-002.
https://doi.org/10.1158/1538-7445.AM2015-LB-002
Published: 01 August 2015
View article titled, Abstract LB-002: A novel c-Met/EGFR bispecific targeting antibody drug conjugate for NSCLC
Journal Articles

miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14

Yiyi Li, Cem Kuscu, Anna Banach, Qian Zhang, Ashleigh Pulkoski-Gross, Deborah Kim, Jingxuan Liu, Eric Roth, Ellen Li, Kenneth R. Shroyer, Paula I. Denoya, Xiaoxia Zhu, Longhua Chen, Jian Cao
Journal: Cancer Research
Cancer Res (2015) 75 (13): 2674–2685.
https://doi.org/10.1158/0008-5472.CAN-14-2875
Published: 30 June 2015
View article titled, miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14
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Includes: Supplementary data
Journal Articles

Abstract P2-16-02: Bi-specific antibodies targeting signaling pathway crosstalk are a new breast cancer immunotherapeutic strategy

Yanliang Zhang, Edwige Gros, Sarabjit Chagar, Jian Cao, Heyue Zhou, Kouros Motamed, Gunnar F Kaufmann, Yanwen Fu
Journal: Cancer Research
Cancer Res (2015) 75 (9_Supplement): P2-16-02.
https://doi.org/10.1158/1538-7445.SABCS14-P2-16-02
Published: 01 May 2015
View article titled, Abstract P2-16-02: Bi-specific antibodies targeting signaling pathway crosstalk are a new breast cancer immunotherapeutic strategy
Journal Articles

Abstract B73: Unraveling the role of a novel endoplasmic reticulum protein in cancer cell migration

Nikki Ann Evensen, Cem Kuscu, Antoine Dufour, Stanley Zucker, Jian Cao
Journal: Cancer Research
Cancer Res (2013) 73 (3_Supplement): B73.
https://doi.org/10.1158/1538-7445.TIM2013-B73
Published: 01 May 2014
View article titled, Abstract B73: Unraveling the role of a novel endoplasmic reticulum protein in cancer cell migration
Journal Articles

Abstract 3949: Hypoxia induces the conversion of tumor initiating cells from stationary to invasive by promoting cell surface trafficking of matrix metalloproteinase-14.

Jian Cao
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3949.
https://doi.org/10.1158/1538-7445.AM2013-3949
Published: 15 April 2013
View article titled, Abstract 3949: Hypoxia induces the conversion of tumor initiating cells from stationary to invasive by promoting cell surface trafficking of matrix metalloproteinase-14.
Journal Articles

Abstract LB-389: The function of histone demethylase RBP2 in breast cancer metastasis and drug resistance

Jian Cao, Zongzhi Liu, Minghui Zhao, Don Nguyen, Qin Yan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-389.
https://doi.org/10.1158/1538-7445.AM2012-LB-389
Published: 15 April 2012
View article titled, Abstract LB-389: The function of histone demethylase RBP2 in breast cancer metastasis and drug resistance
Journal Articles

Abstract 340: MT1-MMP triggers an epithelial to mesenchymal transition program via activation of a TGF-β signaling pathway leading to Wnt5a induction

Hoang-Lan T. Nguyen, Stanley Zucker, Pournima Kadam, Jian Cao
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 340.
https://doi.org/10.1158/1538-7445.AM2012-340
Published: 15 April 2012
View article titled, Abstract 340: MT1-MMP triggers an epithelial to mesenchymal transition program via activation of a TGF-β signaling pathway leading to Wnt5a induction
Journal Articles

Abstract 4313: A novel endoplasmic reticulum protein promotes cancer invasion/metastasis

Nikki A. Evensen, Cem Kuscu, Ashleigh Pulkoski-Gross, Hoang-Lan Nguyen, Stanley Zucker, Jian Cao
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4313.
https://doi.org/10.1158/1538-7445.AM2012-4313
Published: 15 April 2012
View article titled, Abstract 4313: A novel endoplasmic reticulum protein promotes cancer invasion/metastasis
Journal Articles

Small-Molecule Anticancer Compounds Selectively Target the Hemopexin Domain of Matrix Metalloproteinase-9

Antoine Dufour, Nicole S. Sampson, Jian Li, Cem Kuscu, Robert C. Rizzo, Jennifer L. DeLeon, Jizu Zhi, Nadia Jaber, Eric Liu, Stanley Zucker, Jian Cao
Journal: Cancer Research
Cancer Res (2011) 71 (14): 4977–4988.
https://doi.org/10.1158/0008-5472.CAN-10-4552
Published: 14 July 2011
View article titled, Small-Molecule Anticancer Compounds Selectively Target the Hemopexin Domain of Matrix Metalloproteinase-9
Open the PDF for Small-Molecule Anticancer Compounds Selectively Target the Hemopexin Domain of Matrix Metalloproteinase-9 in another window
Includes: Supplementary data
Journal Articles

Abstract 533: Critical role of MMP-9 dimers in cell migration: design of inhibitory peptides

Antoine Dufour, Nicole S. Sampson, Cem Kuscu, Stanley Zucker, Jian Cao
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 533.
https://doi.org/10.1158/1538-7445.AM10-533
Published: 15 April 2010
View article titled, Abstract 533: Critical role of MMP-9 dimers in cell migration: design of inhibitory peptides
Journal Articles

Abstract #2227: Cancer-related invasive gene (CRIG): A key component of breast cancer metastasis

Jian Cao, Pournima Kadam, Hoang-Lan Nguyen, Antoine Dufour, Stanley Zucker
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2227.
Published: 01 May 2009
View article titled, Abstract #2227: Cancer-related invasive gene (CRIG): A key component of breast cancer metastasis
Journal Articles

Role of the hemopexin-like (PEX) domain of membrane type 1-matrix metalloproteinase (MT1-MMP) in cell migration/invasion

Jian Cao, Pallavi Kozarekar, Omer Richman, Tony Dufour, Nicole Sampson, Stanley Zucker
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 3073.
Published: 01 May 2007
View article titled, Role of the hemopexin-like (PEX) domain of membrane type 1-matrix metalloproteinase (MT1-MMP) in cell migration/invasion
Journal Articles

Induction of epithelial to mesenchymal transition (EMT) by membrane type 1-Matrix metalloproteinase (MT1-MMP) is a prerequisite for cancer invasion

Jian Cao, Pallavi Kozarekar
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1023.
Published: 15 April 2006
View article titled, Induction of epithelial to mesenchymal transition (EMT) by membrane type 1-Matrix metalloproteinase (MT1-MMP) is a prerequisite for cancer invasion
Journal Articles

Morpho-functional characterization of the intracellular activation compartment of the integral membrane type 1 matrix metalloprotease

Marco Mazzone, Massimiliano Baldassarre, Galina Beznoussenko, Giada Giacchetti, Jian Cao, Stanley Zucker, Alberto Luini, Roberto Buccione
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 694.
Published: 01 May 2005
View article titled, Morpho-functional characterization of the intracellular activation compartment of the integral membrane type 1 matrix metalloprotease
Journal Articles

Inhibition of prostate cancer cell invasion by targeting the different domains of membrane type 1-matrix metalloproteinase (MT1-MMP)

Jian Cao, Pallavi Kozarekar, Christian Chiarelli
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 694.
Published: 01 May 2005
View article titled, Inhibition of prostate cancer cell invasion by targeting the different domains of membrane type 1-matrix metalloproteinase (MT1-MMP)
Journal Articles

Pivotal roles of membrane type-1 matrix metalloproteinase (MT1-MMP) in prostate cancer invasion and metastasis.

Jian Cao, Pallavi Kozarekar, Howard Adler, Christian Chiarelli, Wadie F. Bahou, Stanley Zucker
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 529.
Published: 01 April 2004
View article titled, Pivotal roles of membrane type-1 matrix metalloproteinase (MT1-MMP) in prostate cancer invasion and metastasis.
Journal Articles

Emmprin Promotes Anchorage-Independent Growth in Human Mammary Carcinoma Cells by Stimulating Hyaluronan Production

Erica A. Marieb, Alexandra Zoltan-Jones, Rongsong Li, Suniti Misra, Shibnath Ghatak, Jian Cao, Stanley Zucker, Bryan P. Toole
Journal: Cancer Research
Cancer Res (2004) 64 (4): 1229–1232.
https://doi.org/10.1158/0008-5472.CAN-03-2832
Published: 18 February 2004
View article titled, Emmprin Promotes Anchorage-Independent Growth in Human Mammary Carcinoma Cells by Stimulating Hyaluronan Production
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