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Jia Luo
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Journal Articles

Abstract PO4-18-07: A dose escalation and cohort expansion study of the CDK9 inhibitor KB-0742 in triple negative breast cancer and transcriptionally addicted relapsed or refractory solid tumors

Monica Mita, Alain Mita, Miguel Villalona-Calero, Noah Federman, Drew Rasco, David Spigel, Jia Luo, Gregory Cote, Richard Cutler, Pavan Kumar, Crystal MacKenzie, Charles Lin, Jorge DiMartino, Elizabeth Olek, Brian Van Tine
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO4-18-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO4-18-07
Published: 02 May 2024
View article titled, Abstract PO4-18-07: A dose escalation and cohort expansion study of the CDK9 inhibitor KB-0742 in triple negative breast cancer and transcriptionally addicted relapsed or refractory solid tumors
Journal Articles

Abstract CT158: A dose escalation and cohort expansion study of the CDK9 inhibitor KB-0742 in relapsed, refractory and transcriptionally addicted solid tumors

Miguel Villalona Calero, Mark Agulnik, Monica Mita, Alain Mita, Noah Federman, Drew Rasco, David Spigel, Jia Luo, Glenn Hanna, Gregory Cote, Mohamad A. Salkeni, Rashmi Chugh, Natraj R. Ammakkanavar, Satish A. Shah, Amol Rao, Kamalesh Kumar Sankhala, Richard E. Cutler, Tressa Hood, Luis Carvajal, Crystal MacKenzie, Charles Lin, Jorge DiMartino, Elizabeth A. Olek, Brian Van Tine
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT158.
https://doi.org/10.1158/1538-7445.AM2024-CT158
Published: 05 April 2024
View article titled, Abstract CT158: A dose escalation and cohort expansion study of the CDK9 inhibitor KB-0742 in relapsed, refractory and transcriptionally addicted solid tumors
Journal Articles

Abstract 2151: Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of KRAS mutations and allele-specific subtypes in non-small cell lung cancer

Xinan Wang, Kangcheng Hou, Biagio Ricciuti, Joao V. Alessi, Xihao Li, Federica Pecci, Rounak Dey, Jia Luo, Mark M. Awad, Alexander Gusev, Xihong Lin, Bruce E. Johnson, David C. Christiani
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 2151.
https://doi.org/10.1158/1538-7445.AM2024-2151
Published: 22 March 2024
View article titled, Abstract 2151: Additional impact of genetic ancestry over self-reported race/ethnicity to prevalence of <em>KRAS</em> mutations and allele-specific subtypes in non-small cell lung cancer
Journal Articles

Abstract B112: A dose escalation and cohort expansion study of the CDK9 inhibitor KB-0742 in relapsed, refractory ovarian cancer and transcriptionally addicted relapsed or refractory solid tumors

Miguel Villalona-Calero, Monica Mita, Alain Mita, Noah Federman, Drew Rasco, David Spigel, Jia Luo, Gregory M. Cote, Richard E. Cutler, Pavan Kumar, Crystal J. MacKenzie, Charles Lin, Jorge F. DiMartino, Elizabeth A. Olek, Brian Van Tine
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): B112.
https://doi.org/10.1158/1538-7445.OVARIAN23-B112
Published: 04 March 2024
View article titled, Abstract B112: A dose escalation and cohort expansion study of the CDK9 inhibitor KB-0742 in relapsed, refractory ovarian cancer and transcriptionally addicted relapsed or refractory solid tumors
Journal Articles

EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes

Yeying Huang, R. Taylor Durall, Nhi M. Luong, Hans J. Hertzler, Julianna Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Nicole S. Persky, David E. Root, Praju V. Anekal, Paula D.L.M. Montero Llopis, Clement N. David, Jeffery L. Kutok, Alejandra Raimondi, Karan Saluja, Jia Luo, Cynthia A. Zahnow, Biniam Adane, Kimberly Stegmaier, Catherine E. Hawkins, Christopher Ponne, Quan Le, Geoffrey I. Shapiro, Madeleine E. Lemieux, Kyle P. Eagen, Christopher A. French
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3956–3973.
https://doi.org/10.1158/0008-5472.CAN-23-1475
Published: 01 December 2023
View article titled, EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes
Open the PDF for EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes in another window
Includes: Supplementary data
Journal Articles

The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma

R. Taylor Durall, Julianna Huang, Luke Wojenski, Yeying Huang, Prafulla C. Gokhale, Brittaney A. Leeper, Joshua O. Nash, Pedro L. Ballester, Scott Davidson, Adam Shlien, Emmanuel Sotirakis, Fabien Bertaux, Vincent Dubus, Jia Luo, Catherine J. Wu, Derin B. Keskin, Kyle P. Eagen, Geoffrey I. Shapiro, Christopher A. French
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3846–3860.
https://doi.org/10.1158/0008-5472.CAN-23-2545
Published: 01 December 2023
View article titled, The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma
Open the PDF for The BRD4–NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract P5-09-05: A phase II, single-arm study of histone deacetylases inhibitor Tucidinostat and Exemestane as neoadjuvant therapy in patients with hormone receptor positive HER2 negative breast cancer (NeoTEE trial)

zhen shan, nan shao, xiaoling zhang, huijuan shi, yanling zheng, jia luo, tiantian zhen, ruping chen, Ying Lin
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P5-09-05.
https://doi.org/10.1158/1538-7445.SABCS22-P5-09-05
Published: 01 March 2023
View article titled, Abstract P5-09-05: A phase II, single-arm study of histone deacetylases inhibitor Tucidinostat and Exemestane as neoadjuvant therapy in patients with hormone receptor positive HER2 negative breast cancer (NeoTEE trial)
Journal Articles

Abstract 4117: Clinicopathologic and molecular characterization of KRASG12D lung cancers

Jia Luo, Biagio Ricciuti, Joao V. Alessi, Xinan Wang, Victor Vaz, Federica Pecci, Tom Nguyen, James Lindsay, Bijaya Sharma, Kristen D. Felt, Scott J. Rodig, Mizuki H. Nishino, Lynette M. Sholl, David A. Barbie, Pasi A. Jänne, Mark M. Awad
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4117.
https://doi.org/10.1158/1538-7445.AM2022-4117
Published: 15 June 2022
View article titled, Abstract 4117: Clinicopathologic and molecular characterization of KRAS<sup>G12D</sup> lung cancers
Journal Articles

Abstract 5720: Niraparib enhances radiosensitivity of glioblastoma cells with proficient BRCA1/2 through proliferation-related nucleolar protein DDX21

Jia Luo, He Xiao, Qian Chen, Yanlan Li, Chuan Chen, Mingying Geng
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5720.
https://doi.org/10.1158/1538-7445.AM2022-5720
Published: 15 June 2022
View article titled, Abstract 5720: Niraparib enhances radiosensitivity of glioblastoma cells with proficient BRCA1/2 through proliferation-related nucleolar protein DDX21
Journal Articles

Abstract 5972: HLJ1 deficiency enhanced diethylnitrosamine-induced hepatocarcinogenesis in a gene targeting mouse model

Wei-Jia Luo, Min-Hui Chien, Jeremy J. W. Chen, Sung-Liang Yu, Pan-Chyr Yang, Kang-Yi Su
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5972.
https://doi.org/10.1158/1538-7445.AM2020-5972
Published: 15 August 2020
View article titled, Abstract 5972: HLJ1 deficiency enhanced diethylnitrosamine-induced hepatocarcinogenesis in a gene targeting mouse model
Journal Articles

Abstract 5360: Ethanol enhances arsenic-induced mutagenesis in colon

Lei Wang, Lisha Kuang, Young-Ok Son, John Andrew Hitron, Pratheeshkumar Poyil, Zhuo Zhang, Jia Luo, Zhigang Wang, Xianglin Shi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5360.
https://doi.org/10.1158/1538-7445.AM2014-5360
Published: 01 October 2014
View article titled, Abstract 5360: Ethanol enhances arsenic-induced mutagenesis in colon
Journal Articles

Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells

Jiajun Cui, Katherine Germer, Tianying Wu, Jiang Wang, Jia Luo, Shao-chun Wang, Qianben Wang, Xiaoting Zhang
Journal: Cancer Research
Cancer Res (2012) 72 (21): 5625–5634.
https://doi.org/10.1158/0008-5472.CAN-12-1305
Published: 31 October 2012
View article titled, Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells
Open the PDF for Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract 5658: Quercetin induces tumor-selective apoptosis involving downregulation of Mcl-1 and activation of Bax

Senping Cheng, Gang Chen, Young-ok Son, Jia Luo, Xianglin Shi
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5658.
https://doi.org/10.1158/1538-7445.AM10-5658
Published: 15 April 2010
View article titled, Abstract 5658: Quercetin induces tumor-selective apoptosis involving downregulation of Mcl-1 and activation of Bax
Journal Articles

Abstract #LB-218: Examination of mutant EGF receptors linked to Non-Small Cell Lung Cancer and their responses to Gefitinib

Jia Luo, Chimera Peet, Paul Bertics
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-218.
Published: 01 May 2009
View article titled, Abstract #LB-218: Examination of mutant EGF receptors linked to Non-Small Cell Lung Cancer and their responses to Gefitinib
Journal Articles

Analysis of basal and EGF-stimulated activity of mutant EGF receptors associated with non-small cell lung cancer and their sensitivity to Gefitinib

Chimera Peet, Jia Luo, Paul Bertics
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 4852.
Published: 01 May 2008
View article titled, Analysis of basal and EGF-stimulated activity of mutant EGF receptors associated with non-small cell lung cancer and their sensitivity to Gefitinib
Journal Articles

The Role of Glycogen Synthase Kinase 3β in the Transformation of Epidermal Cells

Cuiling Ma, Jian Wang, Ying Gao, Tian-Wen Gao, Gang Chen, Kimberly A. Bower, Mohammed Odetallah, Min Ding, Zunji Ke, Jia Luo
Journal: Cancer Research
Cancer Res (2007) 67 (16): 7756–7764.
https://doi.org/10.1158/0008-5472.CAN-06-4665
Published: 15 August 2007
View article titled, The Role of Glycogen Synthase Kinase 3β in the Transformation of Epidermal Cells
Open the PDF for The Role of Glycogen Synthase Kinase 3β in the Transformation of Epidermal Cells in another window