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Journal Articles

Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration

Jian-Hong Fang, Jie-Ying Chen, Jia-Lin Zheng, Hui-Xian Zeng, Jun-Guang Chen, Chen-Hui Wu, Jia-Li Cai, Zhi-Yong Wang, Shi-Mei Zhuang
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1249–1263.
https://doi.org/10.1158/0008-5472.CAN-22-1844
Published: 14 April 2023
View article titled, Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration
Open the PDF for Fructose Metabolism in Tumor Endothelial Cells Promotes Angiogenesis by Activating AMPK Signaling and Mitochondrial Respiration in another window
Includes: Supplementary data
Journal Articles

Abstract 3450: Discovery and preclinical study of novel BTK degrader HZ-Q1070

Xingguo Liu, Yubo Zhou, Yizhe Wu, Xiaomin Luo, Jiangfeng Xie, Xinxin Jin, Jia Li, Xinglu Zhou
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3450.
https://doi.org/10.1158/1538-7445.AM2023-3450
Published: 04 April 2023
View article titled, Abstract 3450: Discovery and preclinical study of novel BTK degrader HZ-Q1070
Journal Articles

Abstract 2153: Cyclin E1 protein overexpression sensitizes ovarian cancer cells to ZN-c3, a novel, selective and oral bioavailable inhibitor of Wee1

Jianhui Ma, Wen Liu, Heekyung Chung, Hooman Izadi, Petrus DeJong, Olivier Harismendy, Jia li, Fernando Doñate, Ahmed Samatar, Mark Lackner, Laure Escoubet, Kevin Bunker, Daehwan Kim, Nathan Jameson, Tugba Yildiran Ozmen, Kangjin Jeong, Dong Zhang, Wen-An Pan, Gordon Mills
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2153.
https://doi.org/10.1158/1538-7445.AM2023-2153
Published: 04 April 2023
View article titled, Abstract 2153: Cyclin E1 protein overexpression sensitizes ovarian cancer cells to ZN-c3, a novel, selective and oral bioavailable inhibitor of Wee1
Journal Articles

Abstract 1911: Racial and ethnic disparities in comorbidity burden among ovarian cancer patients

Lindsay Jane Collin, Valerie Lee, Jia Li, Carola Sanchez Diaz, Bethan Powell, Juraj Kavecansky, Scarlett Lin Gomez, Jennifer Doherty, Elisa V. Bandera, Larry Kushi
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1911.
https://doi.org/10.1158/1538-7445.AM2023-1911
Published: 04 April 2023
View article titled, Abstract 1911: Racial and ethnic disparities in comorbidity burden among ovarian cancer patients
Journal Articles

Abstract 3612: KAT8/SIRT7-medicated fascin-K41 acetylation/deacetylation regulates tumor metastasis

Da-Jia Li, Yin-Wei Cheng, Li-Yan Xu, En-Min Li
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3612.
https://doi.org/10.1158/1538-7445.AM2023-3612
Published: 04 April 2023
View article titled, Abstract 3612: KAT8/SIRT7-medicated fascin-K41 acetylation/deacetylation regulates tumor metastasis
Journal Articles

CircRPN2 Inhibits Aerobic Glycolysis and Metastasis in Hepatocellular Carcinoma

Jia Li, Zhi-Qiang Hu, Song-Yang Yu, Li Mao, Zheng-Jun Zhou, Peng-Cheng Wang, Yu Gong, Sheng Su, Jian Zhou, Jia Fan, Shao-Lai Zhou, Xiao-Wu Huang
Journal: Cancer Research
Cancer Res (2022) 82 (6): 1055–1069.
https://doi.org/10.1158/0008-5472.CAN-21-1259
Published: 15 March 2022
View article titled, CircRPN2 Inhibits Aerobic Glycolysis and Metastasis in Hepatocellular Carcinoma
Open the PDF for CircRPN2 Inhibits Aerobic Glycolysis and Metastasis in Hepatocellular Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma

Joanna D. Wardyn, Michal M. Hoppe, Allison S. Chan, Jia Li, Omer An, Shruthi Venguidessane, Dominic P. Sheng, Henry Yang, Gene W. Yeo, Daniel J. Hodson, Reuben S. Harris, Anand D. Jeyasekharan
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2443.
https://doi.org/10.1158/1538-7445.AM2021-2443
Published: 01 July 2021
View article titled, Abstract 2443: APOBEC3G is a sex-specific determinant of post-transcriptional RNA processing and survival in diffuse large B-cell lymphoma
Journal Articles

Abstract 2100: The impact of race on the relationship between poly-CpG DNA methylation and mRNA expression in cancer with application to epigenome-wide association studies

Ian M. Loveless, Yalei Chen, Sudha Sadasivan, Indrani Datta, Nilesh Gupta, Pamela Paris, Jia Li, Benjamin A. Rybicki, Albert M. Levin
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2100.
https://doi.org/10.1158/1538-7445.AM2021-2100
Published: 01 July 2021
View article titled, Abstract 2100: The impact of race on the relationship between poly-CpG DNA methylation and mRNA expression in cancer with application to epigenome-wide association studies
Journal Articles

Abstract 2106: Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells

Sabeeta Kapoor, Trace Gustafson, Mutian Zhang, Ying-Shiuan Chen, Jia Li, Nhung Nguyen, Jorge Enrique Perez, Wan Mohaiza Dashwood, Praveen Rajendran, Roderick Dashwood
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2106.
https://doi.org/10.1158/1538-7445.AM2021-2106
Published: 01 July 2021
View article titled, Abstract 2106: Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells
Journal Articles

Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes

Minjung Lee, Jianfang Li, Jia Li, Shaohai Fang, Joanna Zhang, Anh Tran Tram Vo, Wei Han, Hongxiang Zeng, Sevinj Isgandarova, Margarita Martinez-Moczygemba, Yubin Zhou, Deqiang Sun, Yun Huang
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (8): 1965–1976.
https://doi.org/10.1158/0008-5472.CAN-20-3213
Published: 15 April 2021
View article titled, Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes
Open the PDF for Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes in another window
Includes: Supplementary data
Journal Articles

Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance

Zi-Qi Zheng, Zhi-Xuan Li, Jia-Li Guan, Xu Liu, Jun-Yan Li, Yue Chen, Li Lin, Jia Kou, Jia-Wei Lv, Lu-Lu Zhang, Guan-Qun Zhou, Rui-Qi Liu, FoPing Chen, Xiao-Jun He, Ying-Qin Li, Feng Li, Si-Si Xu, Jun Ma, Na Liu, Ying Sun
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (23): 5174–5188.
https://doi.org/10.1158/0008-5472.CAN-19-3626
Published: 02 December 2020
View article titled, Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance
Open the PDF for Long Noncoding RNA TINCR-Mediated Regulation of Acetyl-CoA Metabolism Promotes Nasopharyngeal Carcinoma Progression and Chemoresistance in another window
Includes: Supplementary data
Journal Articles

Abstract PO-005: Tet2 inactivation enhances the anti-tumor efficiency of tumor-infiltrating lymphocytes (TILs)

Minjung Lee, Jiangfang Li, Shaohai Fang, Wei Han, Margarita Moczygemba, Yubin Zhou, Jia Li, Deqiang Sun, Yun Huang
Journal: Cancer Research
Cancer Res (2020) 80 (23_Supplement): PO-005.
https://doi.org/10.1158/1538-7445.EPIMETAB20-PO-005
Published: 02 December 2020
View article titled, Abstract PO-005: Tet2 inactivation enhances the anti-tumor efficiency of tumor-infiltrating lymphocytes (TILs)
Journal Articles

Abstract 976: The systematic identification of novel immune checkpoint averting the metastasis of ovarian cancer: The role of IL20/IL24-IL20RA axis

Jia Li, Qin Xuan, JIE SHI, Longlong Wang, Yi Shi, Rong Xiang
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 976.
https://doi.org/10.1158/1538-7445.AM2020-976
Published: 15 August 2020
View article titled, Abstract 976: The systematic identification of novel immune checkpoint averting the metastasis of ovarian cancer: The role of IL20/IL24-IL20RA axis
Journal Articles

Abstract 971: PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells

Darren Qiancheng Tan, Ying Li, Chong Yang, Jia Li, Shi Hao Tan, Desmond W. Chin, Ayako Nakamura-Ishizu, Henry Yang, Toshio Suda
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 971.
https://doi.org/10.1158/1538-7445.AM2019-971
Published: 01 July 2019
View article titled, Abstract 971: PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells
Journal Articles

Abstract 3318: Development of a cfDNA based trans-omics approach for early cancer detection

Yuying Wang, Heng Zhao, Kaijian Ling, Jianchao Zheng, Zhilong Li, Shuangshuang Chen, Jia Li, Chichuan Liu, Guanghui Yang, Hongpo Zhou, Jiaxi Peng, Lili Ye, Liuhong Zeng, Jianlong Sun, Ruijingfang Jiang, Li Deng, Yanzhou Wang, Kezhong Chen, Zhiqing Liang, Fan Yang, Taiping Shi, Mingzhi Ye
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3318.
https://doi.org/10.1158/1538-7445.AM2019-3318
Published: 01 July 2019
View article titled, Abstract 3318: Development of a cfDNA based trans-omics approach for early cancer detection
Journal Articles

Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition

Praveen Rajendran, Gavin Johnson, Li Li, Ying-Shiuan Chen, Mohaiza Dashwood, Nhung Nguyen, Ahmet Ulusan, Furkan Ertem, Mutian Zhang, Jia Li, Deqiang Sun, Yun Huang, Shan Wang, Hon-Chiu Leung, David Lieberman, Laura Beaver, Emily Ho, Mark Bedford, Kyle Chang, Eduardo Vilar, Roderick Dashwood
Journal: Cancer Research
Cancer Res (2019) 79 (5): 918–927.
https://doi.org/10.1158/0008-5472.CAN-18-2003
Published: 01 March 2019
View article titled, Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition
Open the PDF for Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 1257: Human endogenous retrovirus type K (HERV-K) env protein as a vaccine target for HERV-K+ cancer prevention

Feng Wang-Johanning, Jia Li, Ming Li, Gary L. Johanning, Albert Lee, Tianhe Huang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1257.
https://doi.org/10.1158/1538-7445.AM2018-1257
Published: 01 July 2018
View article titled, Abstract 1257: Human endogenous retrovirus type K (HERV-K) <em>env</em> protein as a vaccine target for HERV-K+ cancer prevention
Journal Articles

Abstract 2974: Primary tumor data mining identifies a novel synthetic lethal partner of the BRCA1 mutation in breast cancer

Yihui Shi, Xiaohe Liu, Jia Li, Lidia Sambucetti, Subarna Sinha
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2974.
https://doi.org/10.1158/1538-7445.AM2018-2974
Published: 01 July 2018
View article titled, Abstract 2974: Primary tumor data mining identifies a novel synthetic lethal partner of the BRCA1 mutation in breast cancer
Journal Articles

Abstract 3332: Genome-wide DNA methylation profiling of peripheral blood leukocytes identifies predictors of aggressive prostate cancer

Yuyan Han, Jia Li, Mutian Zhang, Jeri Kim, Xifeng Wu, Deqiang Sun, Jian Gu
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3332.
https://doi.org/10.1158/1538-7445.AM2018-3332
Published: 01 July 2018
View article titled, Abstract 3332: Genome-wide DNA methylation profiling of peripheral blood leukocytes identifies predictors of aggressive prostate cancer
Journal Articles

Abstract 4231: Breast and prostate cancers harbor common somatic copy number alterations that consistently differ by race-ethnicity

Yalei Chen, Jia Li, Sudha Sadasivan, Ruicong She, Indrani Datta, Dhananjay Chitale, Nilesh Gupta, Melissa B. Davis, Craig G. Rogers, Lisa A. Newman, Pamela L. Paris, Benjamin A. Rybicki, Albert M. Levin
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4231.
https://doi.org/10.1158/1538-7445.AM2018-4231
Published: 01 July 2018
View article titled, Abstract 4231: Breast and prostate cancers harbor common somatic copy number alterations that consistently differ by race-ethnicity