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Jessie Yanxiang Guo
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Journal Articles

Abstract 3803: CRISPR screening identifies methionine synthase as a potential therapeutic target in KRAS-driven NSCLC

Free
Wenping Wang, Samuel Wang, Ioana Dobrescu, Hyungsin Kim, Kyle Nunn, Joel Lee, Joshua Martorelli, Fuqian Shi, Eduardo Lopes, Victoria Silva, Hua Zhong, Zhixian Hu, Daniel Herranz, Chang Chan, Eileen White, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3803.
https://doi.org/10.1158/1538-7445.AM2025-3803
Published: 21 April 2025
View articletitled, Abstract 3803: CRISPR screening identifies methionine synthase as a potential therapeutic target in KRAS-driven NSCLC
Journal Articles

Abstract C053: Autophagy regulates MAT2A in response to hypoxia in pancreatic cancer cells

Free
Yang Yang, Wenping Wang, Gilles Rademaker, Mirunalini Ravichandran, Jingjie Hu, Alexander Li, Joseph D. Mancias, Jessie Yanxiang Guo, Rushika M. Perera
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): C053.
https://doi.org/10.1158/1538-7445.PANCA2023-C053
Published: 16 January 2024
View articletitled, Abstract C053: Autophagy regulates MAT2A in response to hypoxia in pancreatic cancer cells
Journal Articles

Abstract 272: Autophagy and MEK inhibition promotes ferroptosis in liver kinase B1 (Lkb1)-deficient Kras-driven lung tumors

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Vrushank Bhatt, Taijin Lan, Wenping Wang, Jerry Kong, Eduardo Cararo Lopes, Khoosheh Khayati, Jianming Wang, Akash Raju, Michael Rangel, Enrique Lopez, Zhixian Sherrie Hu, Xuefei Luo, Xiaoyang Su, Jyoti Malhotra, Wenwei Hu, Sharon R. Pine, Eileen White, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 272.
https://doi.org/10.1158/1538-7445.AM2023-272
Published: 04 April 2023
View articletitled, Abstract 272: Autophagy and MEK inhibition promotes ferroptosis in liver kinase B1 (Lkb1)-deficient Kras-driven lung tumors
Journal Articles

Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer

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Khoosheh Khayati, Vrushank Bhatt, Taijin Lan, Fawzi Alogaili, Wenping Wang, Enrique Lopez, Zhixian Sherrie Hu, Samantha Gokhale, Liam Cassidy, Masashi Narita, Ping Xie, Eileen White, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2022) 82 (23): 4429–4443.
https://doi.org/10.1158/0008-5472.CAN-22-1039
Published: 02 December 2022
View articletitled, Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer
Open the PDF for Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 88: Autophagy inhibition sensitizes liver kinase b1 (LKB1)-deficient kras-driven lung tumors to MEK inhibitor trametinib

Free
Vrushank Dharmesh Bhatt, Taijin Lan, Wenping Wang, Khoosheh Khayati, Eduardo Cararo-Lopes, Jianming Wang, Jerry Kong, Akash Raju, Xuefei Luo, Wenwei Hu, Xiaoyang Su, Eileen White, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 88.
https://doi.org/10.1158/1538-7445.AM2021-88
Published: 01 July 2021
View articletitled, Abstract 88: Autophagy inhibition sensitizes liver kinase b1 (LKB1)-deficient kras-driven lung tumors to MEK inhibitor trametinib
Journal Articles

Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis

Available to Purchase
Jonathan M. Ghergurovich, Mark Esposito, Zihong Chen, Joshua Z. Wang, Vrushank Bhatt, Taijin Lan, Eileen White, Yibin Kang, Jessie Yanxiang Guo, Joshua D. Rabinowitz
Journal: Cancer Research
Cancer Res (2020) 80 (18): 3820–3829.
https://doi.org/10.1158/0008-5472.CAN-19-2486
Published: 15 September 2020
View articletitled, Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis
Open the PDF for Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 5710: Autophagy inhibition sensitizes Liver Kinase B1 (LKB1) - deficient Kras-driven lung tumors to MEK inhibitor Trametinib

Free
Vrushank Dharmesh Bhatt, Khoosheh Khayati, Jerry Kong, Akash Raju, Zhixian Hu, Xiaoyang Su, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5710.
https://doi.org/10.1158/1538-7445.AM2020-5710
Published: 15 August 2020
View articletitled, Abstract 5710: Autophagy inhibition sensitizes Liver Kinase B1 (LKB1) - deficient Kras-driven lung tumors to MEK inhibitor Trametinib
Journal Articles

Abstract 2716: Autophagy modulates lipid metabolism in liver kinase B1 (LKB1)-deficient Kras-driven lung tumorigenesis

Free
Vrushank D. Bhatt, Khoosheh Khayati, Zhixian Hu, Xiaoyang Su, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2716.
https://doi.org/10.1158/1538-7445.AM2019-2716
Published: 01 July 2019
View articletitled, Abstract 2716: Autophagy modulates lipid metabolism in liver kinase B1 (LKB1)-deficient Kras-driven lung tumorigenesis
Journal Articles

Abstract 2421: SOD1 is required for tumor maintenance in a genetically engineered KRAS/TP53 non-small cell lung cancer mouse model

Free
Xiaowen Wang, Justin Wong, Holly Van Remmen, Jessie Yanxiang Guo, Eileen White, X. F. Steven Zheng
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2421.
https://doi.org/10.1158/1538-7445.AM2018-2421
Published: 01 July 2018
View articletitled, Abstract 2421: SOD1 is required for tumor maintenance in a genetically engineered KRAS/TP53 non-small cell lung cancer mouse model
Journal Articles

Abstract 4969: Autophagy modulates lipid metabolism to support Liver Kinase B1 (LKB1) - deficient lung tumor growth

Free
Vrushank D. Bhatt, Zhixian Hu, Xiaoyang Su, Jessie Yanxiang Guo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4969.
https://doi.org/10.1158/1538-7445.AM2018-4969
Published: 01 July 2018
View articletitled, Abstract 4969: Autophagy modulates lipid metabolism to support Liver Kinase B1 (LKB1) - deficient lung tumor growth