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Jeremy Chien
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Journal Articles

Abstract 2448: Chemotherapy drug-induced AXL activation and cell survival signaling via reactive oxygen species that can be inhibited to enhance drug efficacy in mesothelioma

Derek B. Oien, Tamás Garay, Sarah Eckstein, Jeremy Chien
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2448.
https://doi.org/10.1158/1538-7445.AM2018-2448
Published: 01 July 2018
View article titled, Abstract 2448: Chemotherapy drug-induced AXL activation and cell survival signaling via reactive oxygen species that can be inhibited to enhance drug efficacy in mesothelioma
Journal Articles

Abstract 1304: The effect of FoxM1 inhibition with thiostrepton on ovarian cancer immune response and sensitivity to chemotherapy in vitro

Jill Madden, Pingping Fang, Bernard Herrman, Mary Markiewicz, Ryan Moulder, Laird Forrest, Jeremy Chien
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1304.
https://doi.org/10.1158/1538-7445.AM2016-1304
Published: 15 July 2016
View article titled, Abstract 1304: The effect of FoxM1 inhibition with thiostrepton on ovarian cancer immune response and sensitivity to chemotherapy <em>in vitro</em>
Journal Articles

Abstract LB-108: Functional genetic screen to identify genetic determinants of “BRCAness” in ovarian cancer

Pingping Fang, Jeremy Chien
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-108.
https://doi.org/10.1158/1538-7445.AM2016-LB-108
Published: 15 July 2016
View article titled, Abstract LB-108: Functional genetic screen to identify genetic determinants of “BRCAness” in ovarian cancer
Journal Articles

Abstract 2385: Characterization of ECM remodeling in disseminated ovarian cancer as a result of loss of HtrA1 and deregulated TGFB signaling

Megan Cooley, Jeremy Chien, Anirban Mitra, Alfonso Baldi, Andras Czirok, Edina Kosa
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2385.
https://doi.org/10.1158/1538-7445.AM2015-2385
Published: 01 August 2015
View article titled, Abstract 2385: Characterization of ECM remodeling in disseminated ovarian cancer as a result of loss of HtrA1 and deregulated TGFB signaling
Journal Articles

Abstract 1992: Evidence for modulation of FoxM1 by p21 in ovarian cancer

Jill Madden, Jeremy Chien
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1992.
https://doi.org/10.1158/1538-7445.AM2015-1992
Published: 01 August 2015
View article titled, Abstract 1992: Evidence for modulation of FoxM1 by p21 in ovarian cancer
Journal Articles

Abstract 260: Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer

Devin C. Koestler, Prabhakar Chalise, Mine S. Cicek, Julie M. Cunningham, Sebastian Armasu, Melissa C. Larson, Jeremy Chien, Matthew Block, Kimberly R. Kalli, Thomas A. Sellers, Ellen L. Goode, Brooke L. Fridley
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 260.
https://doi.org/10.1158/1538-7445.AM2014-260
Published: 01 October 2014
View article titled, Abstract 260: Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer
Journal Articles

Tumor Hypomethylation at 6p21.3 Associates with Longer Time to Recurrence of High-Grade Serous Epithelial Ovarian Cancer

Chen Wang, Mine S. Cicek, Bridget Charbonneau, Kimberly R. Kalli, Sebastian M. Armasu, Melissa C. Larson, Gottfried E. Konecny, Boris Winterhoff, Jian-Bing Fan, Marina Bibikova, Jeremy Chien, Viji Shridhar, Matthew S. Block, Lynn C. Hartmann, Daniel W. Visscher, Julie M. Cunningham, Keith L. Knutson, Brooke L. Fridley, Ellen L. Goode
Journal: Cancer Research
Cancer Res (2014) 74 (11): 3084–3091.
https://doi.org/10.1158/0008-5472.CAN-13-3198
Published: 29 May 2014
View article titled, Tumor Hypomethylation at 6p21.3 Associates with Longer Time to Recurrence of High-Grade Serous Epithelial Ovarian Cancer
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Journal Articles

APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma

Brandon Leonard, Steven N. Hart, Michael B. Burns, Michael A. Carpenter, Nuri A. Temiz, Anurag Rathore, Rachel I. Vogel, Jason B. Nikas, Emily K. Law, William L. Brown, Ying Li, Yuji Zhang, Matthew J. Maurer, Ann L. Oberg, Julie M. Cunningham, Viji Shridhar, Debra A. Bell, Craig April, David Bentley, Marina Bibikova, R. Keira Cheetham, Jian-Bing Fan, Russell Grocock, Sean Humphray, Zoya Kingsbury, John Peden, Jeremy Chien, Elizabeth M. Swisher, Lynn C. Hartmann, Kimberly R. Kalli, Ellen L. Goode, Hugues Sicotte, Scott H. Kaufmann, Reuben S. Harris
Journal: Cancer Research
Cancer Res (2013) 73 (24): 7222–7231.
https://doi.org/10.1158/0008-5472.CAN-13-1753
Published: 16 December 2013
View article titled, APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma
Open the PDF for APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 2008: Genomic medicine using NexGen sequencing to personalized treatment of metastatic adenoid cystic carcinoma (ADCC).

Chao H. Huang, Yen Hoang, Kay Minn, Andrew Godwin, Jeremy Chien
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2008.
https://doi.org/10.1158/1538-7445.AM2013-2008
Published: 15 April 2013
View article titled, Abstract 2008: Genomic medicine using NexGen sequencing to personalized treatment of metastatic adenoid cystic carcinoma (ADCC).
Journal Articles

Abstract 3179: Targeted re-sequencing of cancer-related genes from matched FFPE and fresh-frozen tumor samples using the Illumina sequencing platform

Marina Bibikova, Jeremy Chien, Vincent Ho, Craig April, Sarah Munchel, Erich Jaeger, Samantha Cooper, Russell Grocock, Fiona Nielsen, Yaman Tarabishy, Daniel Visscher, Megan Manion, Jonathan Liu, Eric Wieben, Lynn Hartmann, Kimberly Kalli, Viji Shridhar, Jian-Bing Fan
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3179.
https://doi.org/10.1158/1538-7445.AM2012-3179
Published: 15 April 2012
View article titled, Abstract 3179: Targeted re-sequencing of cancer-related genes from matched FFPE and fresh-frozen tumor samples using the Illumina sequencing platform
Journal Articles

Abstract 3272: Characterization of mouse oviductal glycoprotein (Ovgp1) promoter driven SV40 T large antigen: fallopian tube cancer and leiomyosarcoma mouse model

Takayo Ota, Ronald J. Marler, Amy C. Clayton, Qing Zhang, Zhou Wei, Viji Shridhar, Jan van Deursen, Yoshihiko Araki, Ichiro Miyoshi, Jeremy Chien
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3272.
https://doi.org/10.1158/1538-7445.AM2012-3272
Published: 15 April 2012
View article titled, Abstract 3272: Characterization of mouse oviductal glycoprotein (Ovgp1) promoter driven SV40 T large antigen: fallopian tube cancer and leiomyosarcoma mouse model
Journal Articles

Abstract 4960: The role of YY1 in paclitaxel-induced cytotoxicity in epithelial ovarian cancer

Tsuyoshi Ota, Takayo Ota, Jeremy Chien, Viji Shridhar, Hirohisa Kurachi
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4960.
https://doi.org/10.1158/1538-7445.AM2012-4960
Published: 15 April 2012
View article titled, Abstract 4960: The role of YY1 in paclitaxel-induced cytotoxicity in epithelial ovarian cancer
Journal Articles

Abstract 1531: HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation

Xiaoping He, Ashwani Khurana, Jacie L Maguire, Jeremy Chien, Viji Shridhar
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1531.
https://doi.org/10.1158/1538-7445.AM2011-1531
Published: 15 April 2011
View article titled, Abstract 1531: HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation
Journal Articles

Abstract 4015: Flavopiridol-induced upregulation of HtrA1 is associated with suppression of its negative transcriptional regulator WT-1 and with enhanced chemosensitivity

Tsuyoshi Ohta, Ashwani Khurana, Jacie Maguire, Xiaoping He, Jeremy Chien, Keith Bible, Viji Shridhar
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4015.
https://doi.org/10.1158/1538-7445.AM2011-4015
Published: 15 April 2011
View article titled, Abstract 4015: Flavopiridol-induced upregulation of HtrA1 is associated with suppression of its negative transcriptional regulator WT-1 and with enhanced chemosensitivity
Journal Articles

HSulf-1 Modulates FGF2- and Hypoxia-Mediated Migration and Invasion of Breast Cancer Cells

Ashwani Khurana, Peng Liu, Pasquale Mellone, Laura Lorenzon, Bruno Vincenzi, Kaustubh Datta, Bo Yang, Robert J. Linhardt, Wilma Lingle, Jeremy Chien, Alfonso Baldi, Viji Shridhar
Journal: Cancer Research
Cancer Res (2011) 71 (6): 2152–2161.
https://doi.org/10.1158/0008-5472.CAN-10-3059
Published: 14 March 2011
View article titled, HSulf-1 Modulates FGF2- and Hypoxia-Mediated Migration and Invasion of Breast Cancer Cells
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Includes: Supplementary data
Journal Articles

Abstract 3276: Characterization of tumors in mouse oviduct-specific glycoprotein 1(Ogp1) promoter-driven SV40 large T antigen

Takayo Ota, Amy C. Clayton, Viji Shridhar, Ichiro Miyoshi, Jeremy Chien
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3276.
https://doi.org/10.1158/1538-7445.AM10-3276
Published: 15 April 2010
View article titled, Abstract 3276: Characterization of tumors in mouse oviduct-specific glycoprotein 1(Ogp1) promoter-driven SV40 large T antigen
Journal Articles

Abstract 3544: Assessment of chemo-response in cells derived from patients with malignant ascites

Abraham Peedicayil, Ramandeep Rattan, Xiaoping He, Kimberly R. Kalli, William A. Cliby, Jeremy Chien, Vijayalakshmi Shridhar
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 3544.
https://doi.org/10.1158/1538-7445.AM10-3544
Published: 15 April 2010
View article titled, Abstract 3544: Assessment of chemo-response in cells derived from patients with malignant ascites
Journal Articles

Downregulation of HtrA1 Promotes Resistance to Anoikis and Peritoneal Dissemination of Ovarian Cancer Cells

Xiaoping He, Takayo Ota, Peng Liu, Changqing Su, Jeremy Chien, Viji Shridhar
Journal: Cancer Research
Cancer Res (2010) 70 (8): 3109–3118.
https://doi.org/10.1158/0008-5472.CAN-09-3557
Published: 14 April 2010
View article titled, Downregulation of HtrA1 Promotes Resistance to Anoikis and Peritoneal Dissemination of Ovarian Cancer Cells
Open the PDF for Downregulation of HtrA1 Promotes Resistance to Anoikis and Peritoneal Dissemination of Ovarian Cancer Cells in another window
Includes: Supplementary data
Journal Articles

Abstract #1183: Down-regulation of HtrA1 Enhances Resistance to Anoikis in Ovarian Cancer Cells

Xiaoping He, Jeremy Chien, Viji Shridhar
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1183.
Published: 01 May 2009
View article titled, Abstract #1183: Down-regulation of HtrA1 Enhances Resistance to Anoikis in Ovarian Cancer Cells
Journal Articles

Abstract #5206: Molecular features and therapeutic targets in stage 1 epithelial ovarian cancer

Takayo Ota, Debra Bell, Jesus Gonzalez-Bosquet, Vijayalakshmi Shridhar, Lynn Hartmann, Jian-Bing Fan, Jeremy Chien
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5206.
Published: 01 May 2009
View article titled, Abstract #5206: Molecular features and therapeutic targets in stage 1 epithelial ovarian cancer