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Journal Articles

Abstract 2152: NT-I7 increases lymphocytes and enhances chemotherapy and immunotherapy efficacy in HNSCC

Zhibin Cui, Jacqueline L. Yee, Hua Li, Yan Zeng, Liam Woerner, Alexandra A. Wolfarth, Sara Ferrando-Martinez, Hyunseok Kang, Jennifer R. Grandis, Matthew H. Spitzer, Daniel E. Johnson

Cancer Res (2025) 85 (8_Supplement_1): 2152.

https://doi.org/10.1158/1538-7445.AM2025-2152

Published: 21 April 2025

View articletitled, Abstract 2152: NT-I7 increases lymphocytes and enhances chemotherapy and immunotherapy efficacy in HNSCC

Journal Articles

Abstract B009: Caspase-8 mutation promotes head and neck squamous cell carcinoma development and resistance to anti-PD-1

Zhibin Cui, Liam C Woerner, Steven R Long, Christopher N Peterson, Nathan K VanLandingham, Andrew Nazarenko, Jennifer R Grandis, Daniel E Johnson

Cancer Res (2025) 85 (5_Supplement): B009.

https://doi.org/10.1158/1538-7445.GENFUNC25-B009

Published: 11 March 2025

View articletitled, Abstract B009: Caspase-8 mutation promotes head and neck squamous cell carcinoma development and resistance to anti-PD-1

Journal Articles

To Tip or Not to Tip: A New Combination for Precision Medicine in Head and Neck Cancer

Rex H. Lee, Daniel E. Johnson, Jennifer R. Grandis

Cancer Res (2023) 83 (19): 3162–3164.

https://doi.org/10.1158/0008-5472.CAN-23-1858

Published: 02 October 2023

View articletitled, To Tip or Not to Tip: A New Combination for Precision Medicine in Head and Neck Cancer

Journal Articles

Mutated HRAS Activates YAP1–AXL Signaling to Drive Metastasis of Head and Neck Cancer

Cancer Res (2023) 83 (7): 1031–1047.

https://doi.org/10.1158/0008-5472.CAN-22-2586

Published: 04 April 2023

View articletitled, Mutated HRAS Activates YAP1–AXL Signaling to Drive Metastasis of Head and Neck Cancer

Includes: Supplementary data

Journal Articles

Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Toni M. Brand, Stefan Hartmann, Neil E. Bhola, Hua Li, Yan Zeng, Rachel A. O'Keefe, Max V. Ranall, Sourav Bandyopadhyay, Margaret Soucheray, Nevan J. Krogan, Carolyn Kemp, Umamaheswar Duvvuri, Theresa LaVallee, Daniel E. Johnson, Michelle A. Ozbun, Julie E. Bauman, Jennifer R. Grandis

Cancer Res (2022) 82 (17): 3188.

https://doi.org/10.1158/0008-5472.CAN-22-1307

Published: 02 September 2022

View articletitled, Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Journal Articles

Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Cancer Res (2022) 82 (17): 3187.

https://doi.org/10.1158/0008-5472.CAN-22-1308

Published: 02 September 2022

View articletitled, Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Journal Articles

Abstract 726: HNSCC-associated caspase-8 mutations mediate resistance to apoptosis and up-regulation of immunosuppressive cytokines

Zhibin Cui, Hadas Tal, Jennifer R. Grandis, Daniel E. Johnson

Cancer Res (2019) 79 (13_Supplement): 726.

https://doi.org/10.1158/1538-7445.AM2019-726

Published: 01 July 2019

View articletitled, Abstract 726: HNSCC-associated caspase-8 mutations mediate resistance to apoptosis and up-regulation of immunosuppressive cytokines

Journal Articles

Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Neil E. Bhola, Valerie M. Jansen, James P. Koch, Hua Li, Luigi Formisano, Janice A. Williams, Jennifer R. Grandis, Carlos L. Arteaga

Cancer Res (2019) 79 (4): 875.

https://doi.org/10.1158/0008-5472.CAN-18-4087

Published: 15 February 2019

View articletitled, Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Journal Articles

BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC

Brandon Leonard, Toni M. Brand, Rachel A. O'Keefe, Eliot D. Lee, Yan Zeng, Jacquelyn D. Kemmer, Hua Li, Jennifer R. Grandis, Neil E. Bhola

Cancer Res (2018) 78 (15): 4331–4343.

https://doi.org/10.1158/0008-5472.CAN-18-0459

Published: 31 July 2018

View articletitled, BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC

Includes: Supplementary data

Journal Articles

Abstract 1972: Targeting the IL-6 signaling pathway overcomes cetuximab resistance in head and neck squamous cell carcinoma

Rachel A. O'Keefe, Neil E. Bhola, David S. Lee, Daniel E. Johnson, Jennifer R. Grandis

Cancer Res (2018) 78 (13_Supplement): 1972.

https://doi.org/10.1158/1538-7445.AM2018-1972

Published: 01 July 2018

View articletitled, Abstract 1972: Targeting the IL-6 signaling pathway overcomes cetuximab resistance in head and neck squamous cell carcinoma

Journal Articles

Abstract 4278: Somatic MAPK pathway mutations are associated with high mutational burden and good survival in head and neck squamous cell carcinoma (HNSCC)

Hoi-Lam Ngan, Andrew Y. Fong, Sharon Chan, Shing Chun Yu, Laura R. H. Ip, Jennifer R. Grandis, Vivian Lui

Cancer Res (2018) 78 (13_Supplement): 4278.

https://doi.org/10.1158/1538-7445.AM2018-4278

Published: 01 July 2018

View articletitled, Abstract 4278: Somatic MAPK pathway mutations are associated with high mutational burden and good survival in head and neck squamous cell carcinoma (HNSCC)

Journal Articles

Abstract CT058: Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative "window of opportunity" study

Umamaheswar Duvvuri, Jonathan George, Seungwon Kim, Diego Alvarado, Veronique Neumeister, Ahmed Chenna, Thomas Hawthorne, Theresa LaVallee, Jennifer R. Grandis, Julie E. Bauman

Cancer Res (2018) 78 (13_Supplement): CT058.

https://doi.org/10.1158/1538-7445.AM2018-CT058

Published: 01 July 2018

View articletitled, Abstract CT058: Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative "window of opportunity" study

Journal Articles

Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Cancer Res (2018) 78 (9): 2383–2395.

https://doi.org/10.1158/0008-5472.CAN-17-1672

Published: 30 April 2018

View articletitled, Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Includes: Supplementary data

Journal Articles

Abstract 4101: Targeting the EGFR/STAT3 axis in NSCLC with resistance to EGFR tyrosine kinase inhibitors using an oligonucleotide-based decoy

Christian Njatcha, Mariya Farooqui, Jennifer R. Grandis, Jill M. Siegfried

Cancer Res (2017) 77 (13_Supplement): 4101.

https://doi.org/10.1158/1538-7445.AM2017-4101

Published: 01 July 2017

View articletitled, Abstract 4101: Targeting the EGFR/STAT3 axis in NSCLC with resistance to EGFR tyrosine kinase inhibitors using an oligonucleotide-based decoy

Journal Articles

Abstract 4108: Targeting IL-6 signaling overcomes cetuximab resistance in head and neck squamous cell carcinoma

Rachel A. O'Keefe, Neil Bhola, Toni M. Brand, Yan Zeng, Daniel E. Johnson, Jennifer R. Grandis

Cancer Res (2017) 77 (13_Supplement): 4108.

https://doi.org/10.1158/1538-7445.AM2017-4108

Published: 01 July 2017

View articletitled, Abstract 4108: Targeting IL-6 signaling overcomes cetuximab resistance in head and neck squamous cell carcinoma

Journal Articles

Abstract 1205: HER3 is a functional molecular target in HPV-associated head and neck cancer

Toni Michel Brand, Stefan Hartmann, Neil Bhola, Noah D. Peyser, Hua Li, Yan Zeng, Max V. Randall, Sourav Bandyopadhyay, Jennifer R. Grandis

Cancer Res (2016) 76 (14_Supplement): 1205.

https://doi.org/10.1158/1538-7445.AM2016-1205

Published: 15 July 2016

View articletitled, Abstract 1205: HER3 is a functional molecular target in HPV-associated head and neck cancer

Journal Articles

Abstract CT119: Phase II study of dasatinib in combination with cetuximab in recurrent/metastatic head and neck squamous cell carcinoma

Laura P. Stabile, Ann Marie Egloff, Pei Zhou, William E. Gooding, Jennifer R. Grandis, Julie E. Bauman

Cancer Res (2016) 76 (14_Supplement): CT119.

https://doi.org/10.1158/1538-7445.AM2016-CT119

Published: 15 July 2016

View articletitled, Abstract CT119: Phase II study of dasatinib in combination with cetuximab in recurrent/metastatic head and neck squamous cell carcinoma

Journal Articles

Abstract 2979: Dual targeting of HER3 and PIK3CA has potent anti-tumor effects in pre-clinical models of HNSCC

Nayel Khan, Kara S. Davis, Neal Godse, Carolyn Kemp, Sucheta Kulkarni, Diego Alvarado, Theresa LaVallee, Jennifer R. Grandis, Umamaheswar Duvvuri

Cancer Res (2016) 76 (14_Supplement): 2979.

https://doi.org/10.1158/1538-7445.AM2016-2979

Published: 15 July 2016

View articletitled, Abstract 2979: Dual targeting of HER3 and PIK3CA has potent anti-tumor effects in pre-clinical models of HNSCC

Journal Articles

Abstract 5243: STAT3 inhibition as chemoprevention in a chemically induced mouse model of HNSCC

Noah D. Peyser, Lin Wang, Marie Acquafondata, Maria Freilino, Hua Li, Yan Zeng, Malabika Sen, William E. Gooding, Daniel E. Johnson, Jennifer R. Grandis

Cancer Res (2016) 76 (14_Supplement): 5243.

https://doi.org/10.1158/1538-7445.AM2016-5243

Published: 15 July 2016

View articletitled, Abstract 5243: STAT3 inhibition as chemoprevention in a chemically induced mouse model of HNSCC

Journal Articles

Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Neil E. Bhola, Valerie M. Jansen, James P. Koch, Hua Li, Luigi Formisano, Janice A. Williams, Jennifer R. Grandis, Carlos L. Arteaga

Cancer Res (2016) 76 (2): 440–452.

https://doi.org/10.1158/0008-5472.CAN-15-1640-T

Published: 14 January 2016

View articletitled, Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

Includes: Supplementary data

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Abstract 2152: NT-I7 increases lymphocytes and enhances chemotherapy and immunotherapy efficacy in HNSCC

Abstract B009: Caspase-8 mutation promotes head and neck squamous cell carcinoma development and resistance to anti-PD-1

To Tip or Not to Tip: A New Combination for Precision Medicine in Head and Neck Cancer

Mutated HRAS Activates YAP1–AXL Signaling to Drive Metastasis of Head and Neck Cancer

Editor's Note: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Correction: Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Abstract 726: HNSCC-associated caspase-8 mutations mediate resistance to apoptosis and up-regulation of immunosuppressive cytokines

Correction: Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

BET Inhibition Overcomes Receptor Tyrosine Kinase–Mediated Cetuximab Resistance in HNSCC

Abstract 1972: Targeting the IL-6 signaling pathway overcomes cetuximab resistance in head and neck squamous cell carcinoma

Abstract 4278: Somatic MAPK pathway mutations are associated with high mutational burden and good survival in head and neck squamous cell carcinoma (HNSCC)

Abstract CT058: Molecular and clinical activity of CDX-3379, an anti-ErbB3 monoclonal antibody, in head and neck squamous cell carcinoma: A preoperative "window of opportunity" study

Cross-talk Signaling between HER3 and HPV16 E6 and E7 Mediates Resistance to PI3K Inhibitors in Head and Neck Cancer

Abstract 4101: Targeting the EGFR/STAT3 axis in NSCLC with resistance to EGFR tyrosine kinase inhibitors using an oligonucleotide-based decoy

Abstract 4108: Targeting IL-6 signaling overcomes cetuximab resistance in head and neck squamous cell carcinoma

Abstract 1205: HER3 is a functional molecular target in HPV-associated head and neck cancer

Abstract CT119: Phase II study of dasatinib in combination with cetuximab in recurrent/metastatic head and neck squamous cell carcinoma

Abstract 2979: Dual targeting of HER3 and PIK3CA has potent anti-tumor effects in pre-clinical models of HNSCC

Abstract 5243: STAT3 inhibition as chemoprevention in a chemically induced mouse model of HNSCC

Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

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