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Jennifer P. Morton
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Journal Articles

Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition

George Sharbeen, Joshua A. McCarroll, Anouschka Akerman, Chantal Kopecky, Janet Youkhana, John Kokkinos, Jeff Holst, Cyrille Boyer, Mert Erkan, David Goldstein, Paul Timpson, Thomas R. Cox, Brooke A. Pereira, Jessica L. Chitty, Sigrid K. Fey, Arafath K. Najumudeen, Andrew D. Campbell, Owen J. Sansom, Rosa Mistica C. Ignacio, Stephanie Naim, Jie Liu, Nelson Russia, Julia Lee, Angela Chou, Amber Johns, Anthony J. Gill, Estrella Gonzales-Aloy, Val Gebski, Yi Fang Guan, Marina Pajic, Nigel Turner, Minoti V. Apte, Thomas P. Davis, Jennifer P. Morton, Koroush S. Haghighi, Jorjina Kasparian, Benjamin J. McLean, Yordanos F. Setargew, Phoebe A. Phillips
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (13): 3461–3479.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-2496
Published: 01 July 2021
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Includes: Supplementary data
Journal Articles

Abstract 4549: Macrophage-epithelial metabolic crosstalk impairs chemotherapy in pancreatic cancer

Christopher J. Halbrook, Corbin Pontious, Ilya Kovalenko, Laura Lapienyte, Stephan Dreyer, Yaqing Zhang, Barbara Nelson, Hanna Hong, Daivid Chang, Jennifer P. Morton, Marina Pasca di Magliano, Costas A. Lyssiotis
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4549.
DOI: https://doi.org/10.1158/1538-7445.AM2019-4549
Published: 01 July 2019
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Journal Articles

Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma

Brittany L. Allen-Petersen, Tyler Risom, Zipei Feng, Zhiping Wang, Zina P. Jenny, Mary C. Thoma, Katherine R. Pelz, Jennifer P. Morton, Owen J. Sansom, Charles D. Lopez, Brett Sheppard, Dale J. Christensen, Michael Ohlmeyer, Goutham Narla, Rosalie C. Sears
Journal: Cancer Research
Cancer Res (2019) 79 (1): 209–219.
DOI: https://doi.org/10.1158/0008-5472.CAN-18-0717
Published: 02 January 2019
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Includes: Supplementary data
Journal Articles

Abstract PR07: A biosensor mouse to predict the dissociation and spread of pancreatic cancer

David Herrmann, Zahra Erami, Sean Warren, Max Nobis, Astrid Magenau, Morghan Lucas, Claire Vennin, Ewan J. McGhee, Wilfred Leung, Nadine Reischmann, Agata Mrowinska, Juliane P. Schwarz, Shereen Kadir, Saadia A. Karim, Andrew D. Campbell, David Gallego-Ortega, Jeffry Evans, Owen J. Sansom, Jennifer P. Morton, Kurt I. Anderson, Paul Timpson
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): PR07.
DOI: https://doi.org/10.1158/1538-7445.EPSO16-PR07
Published: 16 January 2017
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Journal Articles

Abstract A18: The integrin αvβ6 regulates PDAC cell growth and stromal cell behavior

Claire S. Reader, Jennifer P. Morton, Owen J. Sansom, John F. Marshall
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A18.
DOI: https://doi.org/10.1158/1538-7445.PANCA16-A18
Published: 14 December 2016
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Journal Articles

mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer

David R. Driscoll, Saadia A Karim, Makoto Sano, David M. Gay, Wright Jacob, Jun Yu, Yusuke Mizukami, Aarthi Gopinathan, Duncan I. Jodrell, T.R. Jeffry Evans, Nabeel Bardeesy, Michael N. Hall, Brian J. Quattrochi, David S. Klimstra, Simon T. Barry, Owen J. Sansom, Brian C. Lewis, Jennifer P. Morton
Journal: Cancer Research
Series: Author Choice
Cancer Res (2016) 76 (23): 6911–6923.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-0810
Published: 30 November 2016
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Includes: Supplementary data
Journal Articles

Abstract C22: ROCK kinases drive invasive pancreatic tumor growth

Nicola Rath, Shereen Kadir, Jennifer P. Morton, Andreia V. Pinho, Lena Helbig, Linda Julian, Ewan J. McGhee, Gabriela Kalna, Alexei Vazquez, Kurt I. Anderson, Ilse Rooman, Michael S. Samuel, Michael F. Olson
Journal: Cancer Research
Cancer Res (2016) 76 (15_Supplement): C22.
DOI: https://doi.org/10.1158/1538-7445.TME16-C22
Published: 28 July 2016
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Journal Articles

Abstract PR13: The canonical Wnt pathway participates in anchorage-independent growth in a subset of heterogeneous tumor cells derived from a single murine pancreatic tumor

Man Yeung Heung, Bryan Serrels, Jennifer P. Morton, Owen J. Sansom, Valerie Brunton, Margaret C. Frame
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): PR13.
DOI: https://doi.org/10.1158/1538-7445.FBCR11-PR13
Published: 28 October 2014
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Journal Articles

Abstract B31: The use of mouse models of pancreatic cancer to evaluate sensitivity to targeted therapies.

Jennifer P. Morton, Douglas C. Morran, Saadia A. Karim, Nigel B. Jamieson, TR Jeffry Evans, Owen J. Sansom
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B31.
DOI: https://doi.org/10.1158/1538-7445.PANCA2012-B31
Published: 03 April 2014
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Journal Articles

Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer

Max Nobis, Ewan J. McGhee, Jennifer P. Morton, Juliane P. Schwarz, Saadia A. Karim, Jean Quinn, Mike Edward, Andrew D. Campbell, Lynn C. McGarry, T.R. Jeffry Evans, Valerie G. Brunton, Margaret C. Frame, Neil O. Carragher, Yingxiao Wang, Owen J. Sansom, Paul Timpson, Kurt I. Anderson
Journal: Cancer Research
Series: Author Choice
Cancer Res (2013) 73 (15): 4674–4686.
DOI: https://doi.org/10.1158/0008-5472.CAN-12-4545
Published: 31 July 2013
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Includes: Multimedia, Supplementary data
Journal Articles

Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53

Paul Timpson, Ewan J. McGhee, Jennifer P. Morton, Alex von Kriegsheim, Juliane P. Schwarz, Saadia A. Karim, Brendan Doyle, Jean A. Quinn, Neil O. Carragher, Mike Edward, Michael F. Olson, Margaret C. Frame, Valerie G. Brunton, Owen J. Sansom, Kurt I. Anderson
Journal: Cancer Research
Cancer Res (2011) 71 (3): 747–757.
DOI: https://doi.org/10.1158/0008-5472.CAN-10-2267
Published: 01 February 2011
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Includes: Multimedia, Supplementary data