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Journal Articles

Abstract 7226: Development of syngeneic tobacco associated oral cancer models using Trp53 and Cdkn2a mutant mice

Roberto Rangel, Roberto Rangel, Jr, Alanis E. Rodriguez-Rosario, Nicholas Balbin, Liping Dong, Arnoldo Corona, Ahmed Tajmim Noor, Guillermina Lozano, Andrew G. Sikora, Jeffrey N. Myers

Cancer Res (2025) 85 (8_Supplement_1): 7226.

https://doi.org/10.1158/1538-7445.AM2025-7226

Published: 21 April 2025

View articletitled, Abstract 7226: Development of syngeneic tobacco associated oral cancer models using Trp53 and Cdkn2a mutant mice

Journal Articles

Abstract 2585: Mutant p53 gains oncogenic functions through a cytosolic DNA response

Cancer Res (2023) 83 (7_Supplement): 2585.

https://doi.org/10.1158/1538-7445.AM2023-2585

Published: 04 April 2023

View articletitled, Abstract 2585: Mutant p53 gains oncogenic functions through a cytosolic DNA response

Journal Articles

Abstract 619: TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV associated oral squamous cell carcinoma

Yewen Shi, Xiaoyong Ren, Shaolong Cao, Tongxin Xie, Xi Chen, Chieko Michikawa, Abdullah A. Osman, Andrew G. Sikora, Jeffrey N. Myers, Roberto Rangel

Cancer Res (2023) 83 (7_Supplement): 619.

https://doi.org/10.1158/1538-7445.AM2023-619

Published: 04 April 2023

View articletitled, Abstract 619: TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV associated oral squamous cell carcinoma

Journal Articles

Abstract NG07: Cancer takes a nerve: Loss of p53 drives neuron reprogramming in head and neck cancer

Cancer Res (2021) 81 (13_Supplement): NG07.

https://doi.org/10.1158/1538-7445.AM2021-NG07

Published: 01 July 2021

View articletitled, Abstract NG07: Cancer takes a nerve: Loss of p53 drives neuron reprogramming in head and neck cancer

Journal Articles

Abstract 269: Harnessing the mechanical power of nanomachines to treat cancer: Light-activated molecular nanomachines kill melanoma and oral cancer cells

Ciceron Ayala-Orozco, Alexis van Venrooy, Dongdong Liu, Yewen Shi, Jacob Beckham, David Izhaky, James M. Tour, Jeffrey N. Myers, Roberto Rangel

Cancer Res (2021) 81 (13_Supplement): 269.

https://doi.org/10.1158/1538-7445.AM2021-269

Published: 01 July 2021

View articletitled, Abstract 269: Harnessing the mechanical power of nanomachines to treat cancer: Light-activated molecular nanomachines kill melanoma and oral cancer cells

Journal Articles

Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk

Deborah A. Silverman, Vena K. Martinez, Patrick M. Dougherty, Jeffrey N. Myers, George A. Calin, Moran Amit

Cancer Res (2021) 81 (6): 1431–1440.

https://doi.org/10.1158/0008-5472.CAN-20-2793

Published: 15 March 2021

View articletitled, Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk

Journal Articles

Abstract 5027: The mu-opioid receptor antagonist methylnaltrexone can decrease tumorigenesis in head and neck squamous cell carcinoma

Aysegul Gorur, Miguel Patino, Ted Shi, Hideaki Takahashi, Jeffrey N. Myers, Juan P. Cata

Cancer Res (2020) 80 (16_Supplement): 5027.

https://doi.org/10.1158/1538-7445.AM2020-5027

Published: 15 August 2020

View articletitled, Abstract 5027: The mu-opioid receptor antagonist methylnaltrexone can decrease tumorigenesis in head and neck squamous cell carcinoma

Journal Articles

Abstract 5289: Gain-of-function mutant p53 predisposes head and neck keratinocytes and squamous cell carcinoma cells to replicative stress and genomic instability through minichromosome maintenance complex component 5

Mei Zhao, Tianxiao Wang, Chen Zhen, Jing Wang, Curtis R. Pickering, Junjie Chen, Jeffrey N. Myers, Ge Zhou

Cancer Res (2019) 79 (13_Supplement): 5289.

https://doi.org/10.1158/1538-7445.AM2019-5289

Published: 01 July 2019

View articletitled, Abstract 5289: Gain-of-function mutant p53 predisposes head and neck keratinocytes and squamous cell carcinoma cells to replicative stress and genomic instability through minichromosome maintenance complex component 5

Journal Articles

Abstract 4621: Risk stratification and biomarker discovery in HPV-positive oropharynx squamous cell carcinoma determined by HPV and human gene expression profile associations

Frederico O. Gleber-Netto, Xiayu Rao, Kelly Erikson, Keiko Akagi, Faye M. Johnson, Jing Wang, Joseph Califano, Maura L. Gillison, Jeffrey N. Myers, Curtis R. Pickering

Cancer Res (2018) 78 (13_Supplement): 4621.

https://doi.org/10.1158/1538-7445.AM2018-4621

Published: 01 July 2018

View articletitled, Abstract 4621: Risk stratification and biomarker discovery in HPV-positive oropharynx squamous cell carcinoma determined by HPV and human gene expression profile associations

Journal Articles

Abstract 2977: PI3K/mTOR pathway inhibition induces Aurora B mediated cell death in NOTCH1 mutant head and neck squamous (HNSCC) cells

Vaishnavi Sambandam, Li Shen, Pan Tong, Shaohua Peng, Tuhina Mazumdar, Ratnakar Singh, Curtis R. Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick, Faye M. Johnson

Cancer Res (2018) 78 (13_Supplement): 2977.

https://doi.org/10.1158/1538-7445.AM2018-2977

Published: 01 July 2018

View articletitled, Abstract 2977: PI3K/mTOR pathway inhibition induces Aurora B mediated cell death in NOTCH1 mutant head and neck squamous (HNSCC) cells

Journal Articles

Abstract 4646: Pharmacogenomic screen identifies KMT2D mutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma

Tuhina Mazumdar, Nene N. Kalu, Shaohua Peng, Pan Tong, Li Shen, Jing Wang, Jeffrey N. Myers, Curtis R. Pickering, David Brunell, Clifford C. Stephan, Faye M. Johnson

Cancer Res (2018) 78 (13_Supplement): 4646.

https://doi.org/10.1158/1538-7445.AM2018-4646

Published: 01 July 2018

View articletitled, Abstract 4646: Pharmacogenomic screen identifies KMT2D mutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma

Journal Articles

Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties

Cancer Res (2018) 78 (13_Supplement): 5506.

https://doi.org/10.1158/1538-7445.AM2018-5506

Published: 01 July 2018

View articletitled, Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties

Journal Articles

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition

Cancer Res (2018) 78 (3): 781–797.

https://doi.org/10.1158/0008-5472.CAN-17-2802

Published: 31 January 2018

View articletitled, CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition

Includes: Supplementary data

Journal Articles

Abstract 2992: Identification of NOTCH1 inactivating mutation as a therapeutic vulnerability to PI3K/mTOR pathway inhibition in head and neck squamous cell carcinoma (HNSCC)

Vaishnavi Sambandam, Li Shen, Pan Tong, Tuhina Mazumdar, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick, Faye M. Johnson

Cancer Res (2017) 77 (13_Supplement): 2992.

https://doi.org/10.1158/1538-7445.AM2017-2992

Published: 01 July 2017

View articletitled, Abstract 2992: Identification of NOTCH1 inactivating mutation as a therapeutic vulnerability to PI3K/mTOR pathway inhibition in head and neck squamous cell carcinoma (HNSCC)

Journal Articles

Abstract 3816: Mutations of the lim protein ajuba mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell cycle inhibitors

Ming Zhang, Singh Ratnakar, Shaohua Peng, Mazumdar Tuhina, Shen Li, Pan Tong, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Faye M. Johnson

Cancer Res (2017) 77 (13_Supplement): 3816.

https://doi.org/10.1158/1538-7445.AM2017-3816

Published: 01 July 2017

View articletitled, Abstract 3816: Mutations of the lim protein ajuba mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell cycle inhibitors

Journal Articles

Abstract 415: In vivo shRNA library screening to identify novel targets for head and neck squamous cell carcinoma

Curtis R. Pickering, Tongxin Xie, Manish Kumar, Ramya L. Parimi, Liang P. Yang, Jiping Wang, Sahil Seth, Christopher A. Bristow, Alessandro Carugo, Frederick S. Robinson, Giulio F. Draetta, Heath Skinner, Mitchell J. Frederick, Jeffrey N. Myers

Cancer Res (2017) 77 (13_Supplement): 415.

https://doi.org/10.1158/1538-7445.AM2017-415

Published: 01 July 2017

View articletitled, Abstract 415: In vivo shRNA library screening to identify novel targets for head and neck squamous cell carcinoma

Journal Articles

Abstract 1845: Mutant p53 promotes progression and metastasis of mouse oral tumors induced by 4NQO, associated with specific immune infiltrates

Jin Wang, Yuanyuan Zhang, Bingbing Wang, Adel K. El-Naggar, Jeffrey N. Myers, Carlos Caulin

Cancer Res (2017) 77 (13_Supplement): 1845.

https://doi.org/10.1158/1538-7445.AM2017-1845

Published: 01 July 2017

View articletitled, Abstract 1845: Mutant p53 promotes progression and metastasis of mouse oral tumors induced by 4NQO, associated with specific immune infiltrates

Journal Articles

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Cancer Res (2017) 77 (6): 1250–1260.

https://doi.org/10.1158/0008-5472.CAN-16-2179

Published: 14 March 2017

View articletitled, Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Includes: Supplementary data

Journal Articles

Abstract 393: NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma

Faye M. Johnson, Vaishnavi Sambandam, Li Shen, Ming Zhang, Rishi Saigal, Pan Tong, Tuhina Mazumdar, Lauren A. Byers, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick

Cancer Res (2016) 76 (14_Supplement): 393.

https://doi.org/10.1158/1538-7445.AM2016-393

Published: 15 July 2016

View articletitled, Abstract 393: NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma

Journal Articles

Abstract 4054: Efficient identification of integration sites of human papilloma virus (HPV) genome in HPV-related head and neck squamous cell carcinoma cell lines with next-generation sequencing-based novel approach

Takashi Hatano, Daisuke Sano, Hideaki Takahashi, Hiroshi Hyakusoku, Yasuhiro Isono, Shoko Shimada, Kae Sawakuma, Yoshiyuki Watanabe, Hiroyuki Yamamoto, Fumio Itoh, Jeffrey N. Myers, Nobuhiko Oridate

Cancer Res (2016) 76 (14_Supplement): 4054.

https://doi.org/10.1158/1538-7445.AM2016-4054

Published: 15 July 2016

View articletitled, Abstract 4054: Efficient identification of integration sites of human papilloma virus (HPV) genome in HPV-related head and neck squamous cell carcinoma cell lines with next-generation sequencing-based novel approach

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Abstract 7226: Development of syngeneic tobacco associated oral cancer models using Trp53 and Cdkn2a mutant mice

Abstract 2585: Mutant p53 gains oncogenic functions through a cytosolic DNA response

Abstract 619: TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV associated oral squamous cell carcinoma

Abstract NG07: Cancer takes a nerve: Loss of p53 drives neuron reprogramming in head and neck cancer

Abstract 269: Harnessing the mechanical power of nanomachines to treat cancer: Light-activated molecular nanomachines kill melanoma and oral cancer cells

Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk

Abstract 5027: The mu-opioid receptor antagonist methylnaltrexone can decrease tumorigenesis in head and neck squamous cell carcinoma

Abstract 5289: Gain-of-function mutant p53 predisposes head and neck keratinocytes and squamous cell carcinoma cells to replicative stress and genomic instability through minichromosome maintenance complex component 5

Abstract 4621: Risk stratification and biomarker discovery in HPV-positive oropharynx squamous cell carcinoma determined by HPV and human gene expression profile associations

Abstract 2977: PI3K/mTOR pathway inhibition induces Aurora B mediated cell death in NOTCH1 mutant head and neck squamous (HNSCC) cells

Abstract 4646: Pharmacogenomic screen identifies KMT2D mutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma

Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition

Abstract 2992: Identification of NOTCH1 inactivating mutation as a therapeutic vulnerability to PI3K/mTOR pathway inhibition in head and neck squamous cell carcinoma (HNSCC)

Abstract 3816: Mutations of the lim protein ajuba mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell cycle inhibitors

Abstract 415: In vivo shRNA library screening to identify novel targets for head and neck squamous cell carcinoma

Abstract 1845: Mutant p53 promotes progression and metastasis of mouse oral tumors induced by 4NQO, associated with specific immune infiltrates

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Abstract 393: NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma

Abstract 4054: Efficient identification of integration sites of human papilloma virus (HPV) genome in HPV-related head and neck squamous cell carcinoma cell lines with next-generation sequencing-based novel approach

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