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Jeffrey N. Myers
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Journal Articles

Abstract 269: Harnessing the mechanical power of nanomachines to treat cancer: Light-activated molecular nanomachines kill melanoma and oral cancer cells

Ciceron Ayala-Orozco, Alexis van Venrooy, Dongdong Liu, Yewen Shi, Jacob Beckham, David Izhaky, James M. Tour, Jeffrey N. Myers, Roberto Rangel
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 269.
DOI: https://doi.org/10.1158/1538-7445.AM2021-269
Published: 01 July 2021
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Abstract NG07: Cancer takes a nerve: Loss of p53 drives neuron reprogramming in head and neck cancer

Moran Amit, Hideaki Takahashi, Mihnea-Paul Dragomir, Simone Anfossi, Antje Lindemann, Frederico Netto-Glebber, Samantha Tam, Abdullah Osman, Erik Kuntsen, Curtis R. Pickering, Mei Zhao, Xiayu Rao, Jing Wang, Deborah A. Silverman, Carlos Caulin, Assaf Zinger, Ennio Tasciotti, Patrick Dougherty, Adel El-Naggar, George A. Calin, Jeffrey N. Myers
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): NG07.
DOI: https://doi.org/10.1158/1538-7445.AM2021-NG07
Published: 01 July 2021
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Journal Articles

Cancer-Associated Neurogenesis and Nerve-Cancer Cross-talk

Deborah A. Silverman, Vena K. Martinez, Patrick M. Dougherty, Jeffrey N. Myers, George A. Calin, Moran Amit
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1431–1440.
DOI: https://doi.org/10.1158/0008-5472.CAN-20-2793
Published: 15 March 2021
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Abstract 5027: The mu-opioid receptor antagonist methylnaltrexone can decrease tumorigenesis in head and neck squamous cell carcinoma

Aysegul Gorur, Miguel Patino, Ted Shi, Hideaki Takahashi, Jeffrey N. Myers, Juan P. Cata
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5027.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5027
Published: 15 August 2020
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Abstract 5289: Gain-of-function mutant p53 predisposes head and neck keratinocytes and squamous cell carcinoma cells to replicative stress and genomic instability through minichromosome maintenance complex component 5

Mei Zhao, Tianxiao Wang, Chen Zhen, Jing Wang, Curtis R. Pickering, Junjie Chen, Jeffrey N. Myers, Ge Zhou
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 5289.
DOI: https://doi.org/10.1158/1538-7445.AM2019-5289
Published: 01 July 2019
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Abstract 2977: PI3K/mTOR pathway inhibition induces Aurora B mediated cell death in NOTCH1 mutant head and neck squamous (HNSCC) cells

Vaishnavi Sambandam, Li Shen, Pan Tong, Shaohua Peng, Tuhina Mazumdar, Ratnakar Singh, Curtis R. Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2977.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2977
Published: 01 July 2018
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Abstract 5506: NOTCH1 activation in head and neck squamous cell carcinoma leads to growth inhibition, changes in gene expression associated with early differentiation, and acquisition of stem cell-like properties

Chenfei Huang, Shhyam Moorthy, Qiuli Li, Rami Saade, Jiping Wang, Xiayu Rao, Noriaki Tanaka, Jiexin Zhang, Lin Tang, Curtis R. Pickering, Patrick A. Zweidler-McKay, Abdullah A. Osman, Tong-Xin Xie, Eve Shinbrot, Liu Xi, David Wheeler, Adel K. El-Naggar, Jing Wang, Jeffrey N. Myers, Mitchell J. Frederick
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5506.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5506
Published: 01 July 2018
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Journal Articles

Abstract 4646: Pharmacogenomic screen identifies KMT2D mutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma

Tuhina Mazumdar, Nene N. Kalu, Shaohua Peng, Pan Tong, Li Shen, Jing Wang, Jeffrey N. Myers, Curtis R. Pickering, David Brunell, Clifford C. Stephan, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4646.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4646
Published: 01 July 2018
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Abstract 4621: Risk stratification and biomarker discovery in HPV-positive oropharynx squamous cell carcinoma determined by HPV and human gene expression profile associations

Frederico O. Gleber-Netto, Xiayu Rao, Kelly Erikson, Keiko Akagi, Faye M. Johnson, Jing Wang, Joseph Califano, Maura L. Gillison, Jeffrey N. Myers, Curtis R. Pickering
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4621.
DOI: https://doi.org/10.1158/1538-7445.AM2018-4621
Published: 01 July 2018
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Journal Articles

CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition

Mayur A. Gadhikar, Jiexin Zhang, Li Shen, Xiayu Rao, Jing Wang, Mei Zhao, Nene N. Kalu, Faye M. Johnson, Lauren A. Byers, John Heymach, Walter N. Hittelman, Durga Udayakumar, Raj K. Pandita, Tej K. Pandita, Curtis R. Pickering, Abena B. Redwood, Helen Piwnica-Worms, Katharina Schlacher, Mitchell J. Frederick, Jeffrey N. Myers
Journal: Cancer Research
Series: Author Choice
Cancer Res (2018) 78 (3): 781–797.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-2802
Published: 31 January 2018
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Includes: Supplementary data
Journal Articles

Abstract 3816: Mutations of the lim protein ajuba mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell cycle inhibitors

Ming Zhang, Singh Ratnakar, Shaohua Peng, Mazumdar Tuhina, Shen Li, Pan Tong, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3816.
DOI: https://doi.org/10.1158/1538-7445.AM2017-3816
Published: 01 July 2017
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Journal Articles

Abstract 415: In vivo shRNA library screening to identify novel targets for head and neck squamous cell carcinoma

Curtis R. Pickering, Tongxin Xie, Manish Kumar, Ramya L. Parimi, Liang P. Yang, Jiping Wang, Sahil Seth, Christopher A. Bristow, Alessandro Carugo, Frederick S. Robinson, Giulio F. Draetta, Heath Skinner, Mitchell J. Frederick, Jeffrey N. Myers
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 415.
DOI: https://doi.org/10.1158/1538-7445.AM2017-415
Published: 01 July 2017
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Journal Articles

Abstract 1845: Mutant p53 promotes progression and metastasis of mouse oral tumors induced by 4NQO, associated with specific immune infiltrates

Jin Wang, Yuanyuan Zhang, Bingbing Wang, Adel K. El-Naggar, Jeffrey N. Myers, Carlos Caulin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1845.
DOI: https://doi.org/10.1158/1538-7445.AM2017-1845
Published: 01 July 2017
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Abstract 2992: Identification of NOTCH1 inactivating mutation as a therapeutic vulnerability to PI3K/mTOR pathway inhibition in head and neck squamous cell carcinoma (HNSCC)

Vaishnavi Sambandam, Li Shen, Pan Tong, Tuhina Mazumdar, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2992.
DOI: https://doi.org/10.1158/1538-7445.AM2017-2992
Published: 01 July 2017
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Journal Articles

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Bernard Leroy, Mandy L. Ballinger, Fanny Baran-Marszak, Gareth L. Bond, Antony Braithwaite, Nicole Concin, Lawrence A. Donehower, Wafik S. El-Deiry, Pierre Fenaux, Gianluca Gaidano, Anita Langerød, Eva Hellstrom-Lindberg, Richard Iggo, Jacqueline Lehmann-Che, Phuong L. Mai, David Malkin, Ute M. Moll, Jeffrey N. Myers, Kim E. Nichols, Sarka Pospisilova, Patricia Ashton-Prolla, Davide Rossi, Sharon A. Savage, Louise C. Strong, Patricia N. Tonin, Robert Zeillinger, Thorsten Zenz, Joseph F. Fraumeni, Jr, Peter E.M. Taschner, Pierre Hainaut, Thierry Soussi
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (6): 1250–1260.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-2179
Published: 14 March 2017
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Includes: Supplementary data
Journal Articles

Abstract 393: NOTCH1 inactivating mutation mediates sensitivity to PI3K/mTOR inhibitors in head and neck squamous cell carcinoma

Faye M. Johnson, Vaishnavi Sambandam, Li Shen, Ming Zhang, Rishi Saigal, Pan Tong, Tuhina Mazumdar, Lauren A. Byers, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Mitchell Frederick
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 393.
DOI: https://doi.org/10.1158/1538-7445.AM2016-393
Published: 15 July 2016
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Journal Articles

Abstract 4757: Identification of biomarkers that predict response of head and neck squamous cell carcinoma to mitotic inhibitors

Ming Zhang, Shaohua Peng, Tuhina Mazumdar, Vaishnavi Sambandam, Li Shen, Pan Tong, Lerong Li, Lauren Byers, Curtis Pickering, Mitchell Frederick, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4757.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4757
Published: 15 July 2016
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Abstract 4054: Efficient identification of integration sites of human papilloma virus (HPV) genome in HPV-related head and neck squamous cell carcinoma cell lines with next-generation sequencing-based novel approach

Takashi Hatano, Daisuke Sano, Hideaki Takahashi, Hiroshi Hyakusoku, Yasuhiro Isono, Shoko Shimada, Kae Sawakuma, Yoshiyuki Watanabe, Hiroyuki Yamamoto, Fumio Itoh, Jeffrey N. Myers, Nobuhiko Oridate
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4054.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4054
Published: 15 July 2016
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Journal Articles

Abstract 2427: The difference of drug sensitivity between HPV-positive and HPV-negative head and neck squamous cell carcinoma cell lines

Ming Zhang, Tuhina Mazumdar, Shaohua Peng, Pan Tong, Vaishnavi Sambandam, Lauren A. Byers, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2427.
DOI: https://doi.org/10.1158/1538-7445.AM2015-2427
Published: 01 August 2015
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Abstract 417: Integrative drug sensitivity analysis of PI3K /mTOR pathway inhibitors in Head and Neck Squamous Cell Carcinoma (HNSCC)

Vaishnavi Sambandam, Li Shen, Ming Zhang, Rishi Saigal, Lauren A. Byers, Curtis Pickering, Jeffrey N. Myers, Jing Wang, Faye M. Johnson
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 417.
DOI: https://doi.org/10.1158/1538-7445.AM2015-417
Published: 01 August 2015
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