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Jeffrey N. Bruce
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Journal Articles

Abstract 5072: Single cell-based elucidation of molecularly distinct glioblastoma states and drug sensitivity

Free
Lorenzo Tomassoni, Wenting Zhao, Hongxu Ding, Kenneth Egbuji, Pasquale Laise, Mariano J. Alvarez, Julia L. Furnari, Michael G. Argenziano, Matei A. Banu, Jeffrey N. Bruce, Peter D. Canoll, Peter A. Sims, Andrea Califano
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5072.
https://doi.org/10.1158/1538-7445.AM2025-5072
Published: 21 April 2025
View articletitled, Abstract 5072: Single cell-based elucidation of molecularly distinct glioblastoma states and drug sensitivity
Journal Articles

Abstract 984: Dissecting the ecosystem of treatment-naïve melanoma brain metastasis using multi-modal single-cell analysis

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Johannes C. Melms, Jana Biermann, Amit Dipak Amin, Yiping Wang, Somnath Tagore, Massimo Andreatta, Ajay Nair, Meri Rogava, Patricia Ho, Lindsay A. Caprio, Zachary H. Walsh, Shivem Shah, Daniel H. Vacarro, Blake Caldwell, Adrienne M. Luoma, Joseph Driver, Matthew Ingham, Suthee Rapisuwon, Jennifer Wargo, Craig L. Slinguff, Evan Z. Macosco, Fei Chen, Richard Carvajal, Michael B. Atkins, Michael A. Davies, Elham Azizi, Santiago J. Carmona, Hanina Hibshoosh, Peter D. Canoll, Jeffrey N. Bruce, Wenya L. Bi, Gary K. Schwartz, Benjamin Izar
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 984.
https://doi.org/10.1158/1538-7445.AM2022-984
Published: 15 June 2022
View articletitled, Abstract 984: Dissecting the ecosystem of treatment-naïve melanoma brain metastasis using multi-modal single-cell analysis
Journal Articles

MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma

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Yiru Zhang, Trang T.T. Nguyen, Enyuan Shang, Angeliki Mela, Nelson Humala, Aayushi Mahajan, Junfei Zhao, Chang Shu, Consuelo Torrini, Maria J. Sanchez-Quintero, Giulio Kleiner, Elena Bianchetti, Mike-Andrew Westhoff, Catarina M. Quinzii, Georg Karpel-Massler, Jeffrey N. Bruce, Peter Canoll, Markus D. Siegelin
Journal: Cancer Research
Cancer Res (2020) 80 (1): 30–43.
https://doi.org/10.1158/0008-5472.CAN-19-1389
Published: 03 January 2020
View articletitled, MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma
Open the PDF for MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

Abstract B31: Multiparameter profiling of abscopal effect (AbE) in a pediatric fibrosarcoma with EML4-NTRK3 fusion

Free
Robyn D. Gartrell, Jennifer S. Sims, Sunjay M. Barton, Angela Kadenhe-Chiweshe, Filemon Dela Cruz, Andrew T. Turk, Andrew L. Kung, Jeffrey N. Bruce, Yvonne M. Saenger, Darrell J. Yamashiro, Eileen P. Connolly
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): B31.
https://doi.org/10.1158/1538-7445.PEDCA17-B31
Published: 01 October 2018
View articletitled, Abstract B31: Multiparameter profiling of abscopal effect (AbE) in a pediatric fibrosarcoma with EML4-NTRK3 fusion
Journal Articles

Abstract 5103: Notch is a master regulator of mesenchymal transformation and therapeutic resistance in glioma

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Matei A. Banu, Athanassios Dovas, Henar Cuervo, Brianna Pereira, Aayushi Mahajan, Hongxu Ding, Mukesh Bansal, Sergey Pampou, Charles Karan, Andrea Califano, Peter A. Sims, Jan Kitajewski, Jeffrey N. Bruce, Peter Canoll
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5103.
https://doi.org/10.1158/1538-7445.AM2018-5103
Published: 01 July 2018
View articletitled, Abstract 5103: Notch is a master regulator of mesenchymal transformation and therapeutic resistance in glioma
Journal Articles

Abstract 664: Surgery plus adjuvant radiation as a valid treatment option for primary central nervous system lymphoma (PCSNL)

Free
Connor J. Kinslow, Ali I. Rae, Alfred I. Neugut, Christopher M. Adams, Sameer A. Sheth, Guy M. McKhann, Michael B. Sisti, Jeffrey N. Bruce, Fabio M. Iwamoto, Adam M. Sonabend, Tony J. Wang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 664.
https://doi.org/10.1158/1538-7445.AM2018-664
Published: 01 July 2018
View articletitled, Abstract 664: Surgery plus adjuvant radiation as a valid treatment option for primary central nervous system lymphoma (PCSNL)
Journal Articles

Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses

Free
Georg Karpel-Massler, Chiaki Tsuge Ishida, Elena Bianchetti, Chang Shu, Rolando Perez-Lorenzo, Basil Horst, Matei Banu, Kevin A. Roth, Jeffrey N. Bruce, Peter Canoll, Dario C. Altieri, Markus D. Siegelin
Journal: Cancer Research
Cancer Res (2017) 77 (13): 3513–3526.
https://doi.org/10.1158/0008-5472.CAN-16-3424
Published: 02 July 2017
View articletitled, Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses
Open the PDF for Inhibition of Mitochondrial Matrix Chaperones and Antiapoptotic Bcl-2 Family Proteins Empower Antitumor Therapeutic Responses in another window
Includes: Supplementary data
Journal Articles

The Transcriptional Regulatory Network of Proneural Glioma Determines the Genetic Alterations Selected during Tumor Progression

Free
Adam M. Sonabend, Mukesh Bansal, Paolo Guarnieri, Liang Lei, Benjamin Amendolara, Craig Soderquist, Richard Leung, Jonathan Yun, Benjamin Kennedy, Julia Sisti, Samuel Bruce, Rachel Bruce, Reena Shakya, Thomas Ludwig, Steven Rosenfeld, Peter A. Sims, Jeffrey N. Bruce, Andrea Califano, Peter Canoll
Journal: Cancer Research
Cancer Res (2014) 74 (5): 1440–1451.
https://doi.org/10.1158/0008-5472.CAN-13-2150
Published: 02 March 2014
View articletitled, The Transcriptional Regulatory Network of Proneural Glioma Determines the Genetic Alterations Selected during Tumor Progression
Open the PDF for The Transcriptional Regulatory Network of Proneural Glioma Determines the Genetic Alterations Selected during Tumor Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 2618: MDA-9/syntenin is a key regulator of glioma pathogenesis.

Free
Timothy P. Kegelman, Swadesh K. Das, Bin Hu, Mitchell Menezes, Luni Emdad, Santanu Dasgupta, Albert S. Baldwin, Jeffrey N. Bruce, Paul Dent, Maurizio Pellecchia, Devanand Sarkar, Paul B. Fisher
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2618.
https://doi.org/10.1158/1538-7445.AM2013-2618
Published: 15 April 2013
View articletitled, Abstract 2618: MDA-9/syntenin is a key regulator of glioma pathogenesis.
Journal Articles

Convection-Enhanced Delivery of Topotecan into a PDGF-Driven Model of Glioblastoma Prolongs Survival and Ablates Both Tumor-Initiating Cells and Recruited Glial Progenitors

Free
Kim A. Lopez, Aaron M. Tannenbaum, Marcela C. Assanah, Katy Linskey, Jonathan Yun, Alayar Kangarlu, Orlando D. Gil, Peter Canoll, Jeffrey N. Bruce
Journal: Cancer Research
Cancer Res (2011) 71 (11): 3963–3971.
https://doi.org/10.1158/0008-5472.CAN-10-0906
Published: 31 May 2011
View articletitled, Convection-Enhanced Delivery of Topotecan into a PDGF-Driven Model of Glioblastoma Prolongs Survival and Ablates Both Tumor-Initiating Cells and Recruited Glial Progenitors
Open the PDF for Convection-Enhanced Delivery of Topotecan into a PDGF-Driven Model of Glioblastoma Prolongs Survival and Ablates Both Tumor-Initiating Cells and Recruited Glial Progenitors in another window
Includes: Supplementary data
Journal Articles

A C-terminal p53 palindromic tetrapeptide restores full apoptotic potential to mutant p53 cancer cell in vitro and in vivo

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Yuehua Mao, Ramon V. Rosal, Patrick B. Senatus, Yi Li, Yongliang Li, Jeffrey N. Bruce, Paul W. Brandt-Rauf, Robert L. Fine
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 406.
Published: 01 May 2005
View articletitled, A C-terminal p53 palindromic tetrapeptide restores full apoptotic potential to mutant p53 cancer cell in vitro and in vivo
Journal Articles

Somatic Mutations of PTEN in Glioblastoma Multiforme

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Steven I. Wang, Janusz Puc, Jing Li, Jeffrey N. Bruce, Paul Cairns, David Sidransky, Ramon Parsons
Journal: Cancer Research
Cancer Res (1997) 57 (19): 4183–4186.
Published: 01 October 1997
View articletitled, Somatic Mutations of PTEN in Glioblastoma Multiforme
Open the PDF for Somatic Mutations of PTEN in Glioblastoma Multiforme in another window