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Abstract 44: A novel, codon-based method to modulate off-tumor toxicity of chimeric antigen receptor (CAR) T cells

Rolando A. Vedia, Sijie Lu, Anne V. Philips, Anna Sergeeva, Lisa S. St John, Karen Clise-Dwyer, Gheath Alatrash, Jeffrey J. Molldrem

Cancer Res (2024) 84 (6_Supplement): 44.

https://doi.org/10.1158/1538-7445.AM2024-44

Published: 22 March 2024

View articletitled, Abstract 44: A novel, codon-based method to modulate off-tumor toxicity of chimeric antigen receptor (CAR) T cells

Journal Articles

Abstract 2995: Cross-presented serine proteases as immunotherapy targets for lung cancer and osteosarcoma

Cancer Res (2023) 83 (7_Supplement): 2995.

https://doi.org/10.1158/1538-7445.AM2023-2995

Published: 04 April 2023

View articletitled, Abstract 2995: Cross-presented serine proteases as immunotherapy targets for lung cancer and osteosarcoma

Journal Articles

Abstract 5655: preclinical development of a novel anti-tslpr bispecific antibody 1b7/cd3 targeting crlf2-rearranged ph-like b-all

Ze Tian, chunhua shi, Amin AI-Shami, GuoJun Yong, Jason K Allen, Jill Wardell Olson, Melinda G Smith, Qing Chang, Qing Shi, Junping You, Michelle A Gonzalez, Timothy E Lofton, Jasbir Kaur, Qi Zhang, DongXing Zha, Nitin Jain, Marina Y Konopleva, Timothy Heffernan, Jeffrey J Molldrem

Cancer Res (2023) 83 (7_Supplement): 5655.

https://doi.org/10.1158/1538-7445.AM2023-5655

Published: 04 April 2023

View articletitled, Abstract 5655: preclinical development of a novel anti-tslpr bispecific antibody 1b7/cd3 targeting crlf2-rearranged ph-like b-all

Journal Articles

Abstract 1195: Stochastic co-evolution of the adaptive immune system and an evading cancer population

Jason Thomas George, Jeffrey J. Molldrem, Herbert Levine

Cancer Res (2019) 79 (13_Supplement): 1195.

https://doi.org/10.1158/1538-7445.AM2019-1195

Published: 01 July 2019

View articletitled, Abstract 1195: Stochastic co-evolution of the adaptive immune system and an evading cancer population

Journal Articles

Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells

Victor A. Gall, Anne V. Philips, Na Qiao, Karen Clise-Dwyer, Alexander A. Perakis, Mao Zhang, Guy T. Clifton, Pariya Sukhumalchandra, Qing Ma, Sangeetha M. Reddy, Dihua Yu, Jeffrey J. Molldrem, George E. Peoples, Gheath Alatrash, Elizabeth A. Mittendorf

Cancer Res (2017) 77 (19): 5374–5383.

https://doi.org/10.1158/0008-5472.CAN-16-2774

Published: 01 October 2017

View articletitled, Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells

Includes: Supplementary data

Journal Articles

Abstract 3984: Neuropilin-1 mediates neutrophil elastase uptake and antigen cross-presentation in breast cancer cells

Celine Kerros, Satyendra C. Tripathi, Dongxing Zha, Sergeeva Anna, Haley L. Peters, Hiroyuki Katayama, Pariya Sukhumalchandra, Kathryn R. Cox, Alexander A. Perakis, Lisa S. St John, Gheath Alatrash, Elizabeth A. Mittendorf, Karen C. Dwyer, Samir M. Hanash, Jeffrey J. Molldrem

Cancer Res (2017) 77 (13_Supplement): 3984.

https://doi.org/10.1158/1538-7445.AM2017-3984

Published: 01 July 2017

View articletitled, Abstract 3984: Neuropilin-1 mediates neutrophil elastase uptake and antigen cross-presentation in breast cancer cells

Journal Articles

Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone

Mikhail G. Kolonin, Anna Sergeeva, Daniela I. Staquicini, Tracey L. Smith, Christy A. Tarleton, Jeffrey J. Molldrem, Richard L. Sidman, Serena Marchiò, Renata Pasqualini, Wadih Arap

Cancer Res (2017) 77 (12): 3144–3150.

https://doi.org/10.1158/0008-5472.CAN-16-0708

Published: 14 June 2017

View articletitled, Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone

Journal Articles

Abstract IA17: T cell receptor-like antibody 8F4 targets leukemia and non-hematopoietic cancer

Jeffrey J. Molldrem, Anna Sergeeva, Hong He, Amanda C. Herrmann, Tian-Hui Yang, Celine Kerros, Haley Peters, Jin Seon Im, Sapna Parshottam, Sijie Lu, Qing Ma, Karen C. Dwyer, Elizabeth Mittendorf, Gheath Alatrash

Cancer Res (2016) 76 (15_Supplement): IA17.

https://doi.org/10.1158/1538-7445.TME16-IA17

Published: 28 July 2016

View articletitled, Abstract IA17: T cell receptor-like antibody 8F4 targets leukemia and non-hematopoietic cancer

Journal Articles

Abstract 3243: Neutrophil elastase regulates PD-L1 expression in breast cancer

Victor Gall, Anne V. Philips, Akhil Chawla, Na Qiao, Lisa S. St. John, Pariya Sukhumalchandra, Mao Zhang, Jeffrey J. Molldrem, Gheath Alatrash, Elizabeth A. Mittendorf

Cancer Res (2016) 76 (14_Supplement): 3243.

https://doi.org/10.1158/1538-7445.AM2016-3243

Published: 15 July 2016

View articletitled, Abstract 3243: Neutrophil elastase regulates PD-L1 expression in breast cancer

Journal Articles

Abstract 534: Trastuzumab increases uptake and cross-presentation of HER2-derived antigens by dendritic cells

Victor A. Gall, Anne V. Philips, Na Qiao, Karen C. Dwyer, Alexander A. Perakis, Mao Zhang, Pariya Sukhumalchandra, Jeffrey J. Molldrem, Gheath Alatrash, Elizabeth A. Mittendorf

Cancer Res (2016) 76 (14_Supplement): 534.

https://doi.org/10.1158/1538-7445.AM2016-534

Published: 15 July 2016

View articletitled, Abstract 534: Trastuzumab increases uptake and cross-presentation of HER2-derived antigens by dendritic cells

Journal Articles

Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Haven R. Garber, Hannah Beird, Yu Cao, Jianhua Zhang, Rachel Sargent, Pei Lin, Sahil Seth, Xingzhi Song, Huandong Sun, Xizeng Mao, Lisa St John, Karen Clise-Dwyer, Gheath Alatrash, P. Andrew Futreal, Jeffrey J. Molldrem

Cancer Res (2015) 75 (15_Supplement): LB-222.

https://doi.org/10.1158/1538-7445.AM2015-LB-222

Published: 01 August 2015

View articletitled, Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Journal Articles

Abstract 2351: Characterization of Neutrophil elastase uptake in breast cancer: implications for immunotherapy

Celine Kerros, Satyendra C. Tripathi, Anne V. Philips, Gheath Al-Atrash, Kathryn E. Ruisaard, Karen C. Dwyer, Elizabeth A. Mittendorf, Samir Hanash, Jeffrey J. Molldrem

Cancer Res (2015) 75 (15_Supplement): 2351.

https://doi.org/10.1158/1538-7445.AM2015-2351

Published: 01 August 2015

View articletitled, Abstract 2351: Characterization of Neutrophil elastase uptake in breast cancer: implications for immunotherapy

Journal Articles

Abstract 4049: Neutrophil elastase induces post-transcriptional increase of surface MHC class I expression on lung cancer cells

Haley L. Peters, Satyendra C. Tripathi, Hiro Katayama, Celine Kerros, Alex Perakis, Lisa S. St. John, Gheath Al-Atrash, Samir Hanash, Jeffrey J. Molldrem

Cancer Res (2015) 75 (15_Supplement): 4049.

https://doi.org/10.1158/1538-7445.AM2015-4049

Published: 01 August 2015

View articletitled, Abstract 4049: Neutrophil elastase induces post-transcriptional increase of surface MHC class I expression on lung cancer cells

Journal Articles

Abstract P5-04-09: Characterization of neutrophil elastase receptor in breast cancer: Implication for immunotherapy

Celine Kerros, Satyendra C Tripathi, Anne V Philips, Gheath Al-Atrash, Kathryn E Ruisaard, Karen C Dwyer, Elizabeth A Mittendorf, Samir M Hanash, Jeffrey J Molldrem

Cancer Res (2015) 75 (9_Supplement): P5-04-09.

https://doi.org/10.1158/1538-7445.SABCS14-P5-04-09

Published: 01 May 2015

View articletitled, Abstract P5-04-09: Characterization of neutrophil elastase receptor in breast cancer: Implication for immunotherapy

Journal Articles

Abstract 4843: Neutrophil elastase enhances adaptive immunity via increase of peptide presentation and downregulation of T cell inhibitory molecules

Akhil Chawla, Anne V. Philips, Na Qiao, Pariya Sukhumalchandra, Celine Kerros, Gheath Alatrash, Jeffrey J. Molldrem, Elizabeth A. Mittendorf

Cancer Res (2014) 74 (19_Supplement): 4843.

https://doi.org/10.1158/1538-7445.AM2014-4843

Published: 01 October 2014

View articletitled, Abstract 4843: Neutrophil elastase enhances adaptive immunity via increase of peptide presentation and downregulation of T cell inhibitory molecules

Journal Articles

Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response

Elizabeth A. Mittendorf, Gheath Alatrash, Na Qiao, Yun Wu, Pariya Sukhumalchandra, Lisa S. St. John, Anne V. Philips, Haile Xiao, Mao Zhang, Kathryn Ruisaard, Karen Clise-Dwyer, Sijie Lu, Jeffrey J. Molldrem

Cancer Res (2012) 72 (13): 3153–3162.

https://doi.org/10.1158/0008-5472.CAN-11-4135

Published: 01 July 2012

View articletitled, Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response

Includes: Supplementary data

Journal Articles

A PR1-Human Leukocyte Antigen-A2 Tetramer Can Be Used to Isolate Low-Frequency Cytotoxic T Lymphocytes from Healthy Donors That Selectively Lyse Chronic Myelogenous Leukemia

Jeffrey J. Molldrem, Peter P. Lee, Changqing Wang, Richard E. Champlin, Mark M. Davis

Cancer Res (1999) 59 (11): 2675–2681.

Published: 01 June 1999

View articletitled, A PR1-Human Leukocyte Antigen-A2 Tetramer Can Be Used to Isolate Low-Frequency Cytotoxic T Lymphocytes from Healthy Donors That Selectively Lyse Chronic Myelogenous Leukemia

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Abstract 44: A novel, codon-based method to modulate off-tumor toxicity of chimeric antigen receptor (CAR) T cells

Abstract 2995: Cross-presented serine proteases as immunotherapy targets for lung cancer and osteosarcoma

Abstract 5655: preclinical development of a novel anti-tslpr bispecific antibody 1b7/cd3 targeting crlf2-rearranged ph-like b-all

Abstract 1195: Stochastic co-evolution of the adaptive immune system and an evading cancer population

Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells

Abstract 3984: Neuropilin-1 mediates neutrophil elastase uptake and antigen cross-presentation in breast cancer cells

Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone

Abstract IA17: T cell receptor-like antibody 8F4 targets leukemia and non-hematopoietic cancer

Abstract 3243: Neutrophil elastase regulates PD-L1 expression in breast cancer

Abstract 534: Trastuzumab increases uptake and cross-presentation of HER2-derived antigens by dendritic cells

Abstract LB-222: Long-term subclonal evolution of CLL from immune selective pressure after allogeneic stem cell transplant and donor lymphocyte infusion

Abstract 2351: Characterization of Neutrophil elastase uptake in breast cancer: implications for immunotherapy

Abstract 4049: Neutrophil elastase induces post-transcriptional increase of surface MHC class I expression on lung cancer cells

Abstract P5-04-09: Characterization of neutrophil elastase receptor in breast cancer: Implication for immunotherapy

Abstract 4843: Neutrophil elastase enhances adaptive immunity via increase of peptide presentation and downregulation of T cell inhibitory molecules

Breast Cancer Cell Uptake of the Inflammatory Mediator Neutrophil Elastase Triggers an Anticancer Adaptive Immune Response

A PR1-Human Leukocyte Antigen-A2 Tetramer Can Be Used to Isolate Low-Frequency Cytotoxic T Lymphocytes from Healthy Donors That Selectively Lyse Chronic Myelogenous Leukemia

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