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Jeffrey H. Becker
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Journal Articles

Abstract 3097: MNK1/2 kinase expression in immune cells dictates tumoral response to MNK inhibitors

Free
Thao D. Pham, Apurba Majumder, Alejandra M. Marinelarena, Jeffrey H. Becker, Hidayatullah G. Munshi
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3097.
https://doi.org/10.1158/1538-7445.AM2025-3097
Published: 21 April 2025
View articletitled, Abstract 3097: MNK1/2 kinase expression in immune cells dictates tumoral response to MNK inhibitors
Journal Articles

Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer

Open Access
Jeffrey H. Becker, Anastasia E. Metropulos, Christina Spaulding, Alejandra M. Marinelarena, Mario A. Shields, Daniel R. Principe, Thao D. Pham, Hidayatullah G. Munshi
Journal: Cancer Research
Cancer Res (2024) 84 (21): 3629–3639.
https://doi.org/10.1158/0008-5472.CAN-23-3574
Published: 04 November 2024
View articletitled, Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
Open the PDF for Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract LB453: Distinct mechanism of CXCR7 activation in EGFR-mutated NSCLC by chemokines

Free
Laura C. Gunder, Ines Pulido, Jeffrey H. Becker, Malek G. Massad, Takeshi Shimamura
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB453.
https://doi.org/10.1158/1538-7445.AM2024-LB453
Published: 05 April 2024
View articletitled, Abstract LB453: Distinct mechanism of CXCR7 activation in EGFR-mutated NSCLC by chemokines
Journal Articles

Endothelin-1–Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma

Available to Purchase
Inés Pulido, Stephen Ollosi, Salvador Aparisi, Jeffrey H. Becker, Alicia Aliena-Valero, Marta Benet, María L. Rodríguez, Adrián López, Eva Tamayo-Torres, Lourdes Chuliá-Peris, Juan Carlos García-Cañaveras, Margaret Soucheray, Annika V. Dalheim, Juan B. Salom, Wei Qiu, Simon Kaja, Javier Alcácer Fernández-Coronado, Sandra Alandes, Javier Alcácer, Fátima Al-Shahrour, Jeffrey A. Borgia, Oscar Juan, Michael I. Nishimura, Agustín Lahoz, Julián Carretero, Takeshi Shimamura
Journal: Cancer Research
Cancer Res (2020) 80 (19): 4224–4232.
https://doi.org/10.1158/0008-5472.CAN-20-0141
Published: 02 October 2020
View articletitled, Endothelin-1–Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma
Open the PDF for Endothelin-1–Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma in another window
Includes: Supplementary data
Journal Articles

CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

Free
Jeffrey H. Becker, Yandi Gao, Margaret Soucheray, Ines Pulido, Eiki Kikuchi, María L. Rodríguez, Rutu Gandhi, Aranzazu Lafuente-Sanchis, Miguel Aupí, Javier Alcácer Fernández-Coronado, Paloma Martín-Martorell, Antonio Cremades, José M. Galbis-Caravajal, Javier Alcácer, Camilla L. Christensen, Patricia Simms, Ashley Hess, Hajime Asahina, Michael P. Kahle, Fatima Al-Shahrour, Jeffrey A. Borgia, Agustín Lahoz, Amelia Insa, Oscar Juan, Pasi A. Jänne, Kwok-Kin Wong, Julian Carretero, Takeshi Shimamura
Journal: Cancer Research
Cancer Res (2019) 79 (17): 4439–4452.
https://doi.org/10.1158/0008-5472.CAN-19-0024
Published: 03 September 2019
View articletitled, CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC
Open the PDF for CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC in another window
Includes: Supplementary data
Journal Articles

Abstract LB-085: A new role for LKB1 to regulate Heat Shock Protein 90 activity

Free
Jeffrey H. Becker, Michael P. Kahle, Margaret Soucheray, Ines Pulido, Fatima Al-Shahrour, Manuel Sanchez del Pino, Kwok-Kin Wong, Julian Carretero, Takeshi Shimamura
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-085.
https://doi.org/10.1158/1538-7445.AM2018-LB-085
Published: 01 July 2018
View articletitled, Abstract LB-085: A new role for LKB1 to regulate Heat Shock Protein 90 activity
Journal Articles

Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition

Free
Margaret Soucheray, Marzia Capelletti, Inés Pulido, Yanan Kuang, Cloud P. Paweletz, Jeffrey H. Becker, Eiki Kikuchi, Chunxiao Xu, Tarun B. Patel, Fatima Al-shahrour, Julián Carretero, Kwok-Kin Wong, Pasi A. Jänne, Geoffrey I. Shapiro, Takeshi Shimamura
Journal: Cancer Research
Cancer Res (2015) 75 (20): 4372–4383.
https://doi.org/10.1158/0008-5472.CAN-15-0377
Published: 14 October 2015
View articletitled, Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition
Open the PDF for Intratumoral Heterogeneity in EGFR-Mutant NSCLC Results in Divergent Resistance Mechanisms in Response to EGFR Tyrosine Kinase Inhibition in another window
Includes: Supplementary data
Journal Articles

Abstract 766: Suppression of gefitinib-induced EMT in EGFR mutant NSCLC preferentially selects for acquired T790M

Free
Margaret Soucheray, Marzia Capelletti, Ines Pulido, Yunan Kuang, Cloud P. Paweletz, Jeffrey H. Becker, Eiki Kikuchi, Chunxiao Xu, Tarun B. Patel, Fatima Al-shahrour, Julian Carretero, Kwok-Kin Wong, Pasi A. Janne, Geoffrey I. Shapiro, Takeshi Shimamura
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 766.
https://doi.org/10.1158/1538-7445.AM2015-766
Published: 01 August 2015
View articletitled, Abstract 766: Suppression of gefitinib-induced EMT in EGFR mutant NSCLC preferentially selects for acquired T790M