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Journal Articles

Abstract 4197: Interaction of B lymphoma cells with the microenvironment affects ibrutinib sensitivity

Hsu-Ping Kuo, Sidney Hsieh, Mint Sirisawad, Chun-Te Chen, Leo W. Cheung, Karl J. Schweighofer, Chia-Lin Hsu, Chi-Ling Fu, Jing Liu, Shiquan Wu, Karl Eckert, Hugh Wang, Mutiah Apatira, Kamaldeep Dhami, Kevin Kwei, Jeff Hsu, Betty Y. Chang

Cancer Res (2017) 77 (13_Supplement): 4197.

https://doi.org/10.1158/1538-7445.AM2017-4197

Published: 01 July 2017

View article titled, Abstract 4197: Interaction of B lymphoma cells with the microenvironment affects ibrutinib sensitivity

Journal Articles

Abstract 167: Ibrutinib regulates tumor microenvironment and enhances response to everolimus in renal cell carcinoma mouse models

Jun Chen, Chun-Te Chen, Jing Liu, Jeff Hsu, Taisei Kinoshita, Betty Y. Chang

Cancer Res (2017) 77 (13_Supplement): 167.

https://doi.org/10.1158/1538-7445.AM2017-167

Published: 01 July 2017

View article titled, Abstract 167: Ibrutinib regulates tumor microenvironment and enhances response to everolimus in renal cell carcinoma mouse models

Journal Articles

Abstract 2321: Ibrutinib enhances antitumor activity in solid tumors when combined with checkpoint inhibitors

Jeff Hsu, Yujun Huang, Chun-Te Chen, Jun Chen, Mint Sirisawad, Betty Y. Chang

Cancer Res (2016) 76 (14_Supplement): 2321.

https://doi.org/10.1158/1538-7445.AM2016-2321

Published: 15 July 2016

View article titled, Abstract 2321: Ibrutinib enhances antitumor activity in solid tumors when combined with checkpoint inhibitors

Journal Articles

Abstract 3072: Combination of ibrutinib and corticosteroids in B-cell non-Hodgkin lymphomas (NHL)

Hsu-Ping Kuo, Sidney Hsieh, Karl J. Schweighofer, Leo WK Cheung, Mutiah Apatira, Mint Sirisawad, Shiquan Wu, Karl Eckert, Yu Liang, Jeff Hsu, Chun-Te Chen, Darrin Beaupre, Betty Y. Chang

Cancer Res (2016) 76 (14_Supplement): 3072.

https://doi.org/10.1158/1538-7445.AM2016-3072

Published: 15 July 2016

View article titled, Abstract 3072: Combination of ibrutinib and corticosteroids in B-cell non-Hodgkin lymphomas (NHL)

Journal Articles

Abstract 4860: The BTK inhibitor ibrutinib modulates T cell immunity in mouse models and in differentiated human T cells

Yujun Huang, Jeff Hsu, Mint Sirisawad, Hsu-Ping Kuo, Betty Y. Chang

Cancer Res (2016) 76 (14_Supplement): 4860.

https://doi.org/10.1158/1538-7445.AM2016-4860

Published: 15 July 2016

View article titled, Abstract 4860: The BTK inhibitor ibrutinib modulates T cell immunity in mouse models and in differentiated human T cells

Journal Articles

Abstract CT315: IG-002 Phase 3 data: Absence of correlation between unbound paclitaxel and response in MBC

Monica Choi, Jeff Hsu, Vuong Trieu

Cancer Res (2014) 74 (19_Supplement): CT315.

https://doi.org/10.1158/1538-7445.AM2014-CT315

Published: 01 October 2014

View article titled, Abstract CT315: IG-002 Phase 3 data: Absence of correlation between unbound paclitaxel and response in MBC

Journal Articles

Abstract LB-227: Preclinical pharmacology and clinical efficacy of AZD9150 (ISIS-STAT3Rx), a potent next-generation antisense oligonucleotide inhibitor of STAT3

Cancer Res (2014) 74 (19_Supplement): LB-227.

https://doi.org/10.1158/1538-7445.AM2014-LB-227

Published: 01 October 2014

View article titled, Abstract LB-227: Preclinical pharmacology and clinical efficacy of AZD9150 (ISIS-STAT3Rx), a potent next-generation antisense oligonucleotide inhibitor of STAT3

Journal Articles

Abstract LB-317: Potent in vivo pharmacology of AZD9150, a next-generation, constrained ethyl-modified antisense oligonucleotide targeting STAT3 in multiple preclinical cancer models.

Youngsoo Kim, Jeff Hsu, Tianyuan Zhou, Nancy Zhang, Richard Woessner, Murali VP Nadella, Deborah Lawson, Corinne Reimer, Guobin He, Joanna Schmidt, Xiaokun Xiao, Sarah Greenlee, Gourab Bhattacharjee, Gene Hung, Brett P. Monia, A. Robert MacLeod

Cancer Res (2013) 73 (8_Supplement): LB-317.

https://doi.org/10.1158/1538-7445.AM2013-LB-317

Published: 15 April 2013

View article titled, Abstract LB-317: Potent <em>in vivo</em> pharmacology of AZD9150, a next-generation, constrained ethyl-modified antisense oligonucleotide targeting STAT3 in multiple preclinical cancer models.

Journal Articles

Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model .

Tony Gutschner, Monika Hämmerle, Moritz Eißmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs

Cancer Res (2013) 73 (8_Supplement): 1121.

https://doi.org/10.1158/1538-7445.AM2013-1121

Published: 15 April 2013

View article titled, Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model .

Journal Articles

Abstract B23: Selective inhibition of a long non-coding RNA (lncRNA), MALAT1 by antisense oligonucleotides results in significant anti-tumor effects in a variety of preclinical cancer models

Jeff Hsu, Guobin He, Gourab Bhattacharjee, Tianyuan Zhou, Chris May, Xiaokun Xiao, Gene Hung, Brett P. Monia, A. Robert MacLeod, Youngsoo Kim

Cancer Res (2012) 72 (2_Supplement): B23.

https://doi.org/10.1158/1538-7445.NONRNA12-B23

Published: 03 April 2013

View article titled, Abstract B23: Selective inhibition of a long non-coding RNA (lncRNA), MALAT1 by antisense oligonucleotides results in significant anti-tumor effects in a variety of preclinical cancer models

Journal Articles

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Tony Gutschner, Monika Hämmerle, Moritz Eißmann, Jeff Hsu, Youngsoo Kim, Gene Hung, Alexey Revenko, Gayatri Arun, Marion Stentrup, Matthias Groß, Martin Zörnig, A. Robert MacLeod, David L. Spector, Sven Diederichs

Cancer Res (2013) 73 (3): 1180–1189.

https://doi.org/10.1158/0008-5472.CAN-12-2850

Published: 31 January 2013

View article titled, The Noncoding RNA <em>MALAT1</em> Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Includes: Supplementary data

Journal Articles

Abstract 2951: Potent antisense pharmacology of highly optimized antisense oligonucleotides in multiple transgenic, spontaneous and patient derived xenograft models of cancer reveals antitumor activity for the non-coding RNA MALAT-1.

Jeff Hsu, Guobin He, Gourab Bhattacharjee, Tianyuan Zhou, Chris May, Brett P. Monia, Youngsoo Kim, A Robert MacLeod

Cancer Res (2012) 72 (8_Supplement): 2951.

https://doi.org/10.1158/1538-7445.AM2012-2951

Published: 15 April 2012

View article titled, Abstract 2951: Potent antisense pharmacology of highly optimized antisense oligonucleotides in multiple transgenic, spontaneous and patient derived xenograft models of cancer reveals antitumor activity for the non-coding RNA MALAT-1.

Journal Articles

Abstract LB-302: Inhibition of STAT3 following systemic delivery of STAT3 antisense oligonucleotide results in target inhibition in tumor and tumor-associated stromal cells and dramatic reduction in circulating pro-tumorigenic cytokines

Youngsoo Kim, Jeff Hsu, Tianyuan Zhou, Guobin He, Chris May, Brett P. Monia, Robert MacLeod

Cancer Res (2011) 71 (8_Supplement): LB-302.

https://doi.org/10.1158/1538-7445.AM2011-LB-302

Published: 15 April 2011

View article titled, Abstract LB-302: Inhibition of STAT3 following systemic delivery of STAT3 antisense oligonucleotide results in target inhibition in tumor and tumor-associated stromal cells and dramatic reduction in circulating pro-tumorigenic cytokines

NARROW

Abstract 4197: Interaction of B lymphoma cells with the microenvironment affects ibrutinib sensitivity

Abstract 167: Ibrutinib regulates tumor microenvironment and enhances response to everolimus in renal cell carcinoma mouse models

Abstract 2321: Ibrutinib enhances antitumor activity in solid tumors when combined with checkpoint inhibitors

Abstract 3072: Combination of ibrutinib and corticosteroids in B-cell non-Hodgkin lymphomas (NHL)

Abstract 4860: The BTK inhibitor ibrutinib modulates T cell immunity in mouse models and in differentiated human T cells

Abstract CT315: IG-002 Phase 3 data: Absence of correlation between unbound paclitaxel and response in MBC

Abstract LB-227: Preclinical pharmacology and clinical efficacy of AZD9150 (ISIS-STAT3Rx), a potent next-generation antisense oligonucleotide inhibitor of STAT3

Abstract LB-317: Potent in vivo pharmacology of AZD9150, a next-generation, constrained ethyl-modified antisense oligonucleotide targeting STAT3 in multiple preclinical cancer models.

Abstract 1121: The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model .

Abstract B23: Selective inhibition of a long non-coding RNA (lncRNA), MALAT1 by antisense oligonucleotides results in significant anti-tumor effects in a variety of preclinical cancer models

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

Abstract 2951: Potent antisense pharmacology of highly optimized antisense oligonucleotides in multiple transgenic, spontaneous and patient derived xenograft models of cancer reveals antitumor activity for the non-coding RNA MALAT-1.

Abstract LB-302: Inhibition of STAT3 following systemic delivery of STAT3 antisense oligonucleotide results in target inhibition in tumor and tumor-associated stromal cells and dramatic reduction in circulating pro-tumorigenic cytokines

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