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Abstract 1232: Xerna࣪ TME Panel: A pan-cancer RNA-based investigational assay designed to predict patient responses to angiogenic and immune targeted therapies

Seema Iyer, Luka Ausec, Daniel Pointing, Matjaz Zganec, Robert Cvitkovic, Miha Stajdohar, Valerie Chamberlain Santos, Kerry Culm, Mokenge Malafa, Jeeyun Lee, Rafael Rosengarten, Laura Benjamin, Mark T. Uhlik

Cancer Res (2022) 82 (12_Supplement): 1232.

DOI: https://doi.org/10.1158/1538-7445.AM2022-1232

Published: 15 June 2022

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Journal Articles

Abstract 6352: Ascites derived exosomes promote progression of advanced gastric cancers

Sujin Hyung, Jihoon Ko, In-kyung Lee, Noo Li Jeon, Jeeyun Lee

Cancer Res (2022) 82 (12_Supplement): 6352.

DOI: https://doi.org/10.1158/1538-7445.AM2022-6352

Published: 15 June 2022

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Journal Articles

Abstract 3206: Three-dimensional tumor angiogenesis mapping in metastatic gastric cancer patients

Jihoon Ko, Sujin Hyung, Minae An, Noo Li Jeon, Jeeyun Lee

Cancer Res (2022) 82 (12_Supplement): 3206.

DOI: https://doi.org/10.1158/1538-7445.AM2022-3206

Published: 15 June 2022

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Journal Articles

Abstract CT218: Phase 1/2 study of a novel HER2 targeting TLR7/8 immune-stimulating antibody conjugate (ISAC), BDC-1001, alone and in combination with pembrolizumab (pembro) in patients (pts) with HER2-expressing advanced solid tumors

Cancer Res (2021) 81 (13_Supplement): CT218.

DOI: https://doi.org/10.1158/1538-7445.AM2021-CT218

Published: 01 July 2021

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Abstract OT-03-02: Phase 1/2 study of a novel HER2 targeting TLR7/8 immune-stimulating antibody conjugate (ISAC), BDC-1001, as a single agent and in combination with an immune checkpoint inhibitor in patients with advanced HER2-expressing solid tumors

Cancer Res (2021) 81 (4_Supplement): OT-03-02.

DOI: https://doi.org/10.1158/1538-7445.SABCS20-OT-03-02

Published: 15 February 2021

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Journal Articles

Abstract 793: Association of serine/threonine kinase 11 mutations and response to programmed cell death 1 inhibitors in metastatic gastric cancer

Minsuk Kwon, Kyung Kim, Suhye Choi, Jung Yong Hong, Seung Tae Kim, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Kyoung-Mee Kim, Jeeyun Lee

Cancer Res (2020) 80 (16_Supplement): 793.

DOI: https://doi.org/10.1158/1538-7445.AM2020-793

Published: 15 August 2020

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Journal Articles

Abstract 2912: The impact of primary tumor sidedness on the effect of regorafenib in refractory metastatic colorectal cancer

Sang Eun Yoon, Joon Young Hur, Su Jin Lee, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Young Suk Park, Seung Tae Kim

Cancer Res (2019) 79 (13_Supplement): 2912.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2912

Published: 01 July 2019

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Abstract 1107: LAG3 in Solid Tumors as a Potential Novel Immunotherapy Target

Su Jin Lee, Sun-ju Byeon, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Won Ki Kang, Ho Yeong Lim, Kyoung-Mee Kim, Seung Tae Kim

Cancer Res (2019) 79 (13_Supplement): 1107.

DOI: https://doi.org/10.1158/1538-7445.AM2019-1107

Published: 01 July 2019

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Journal Articles

Abstract 3605: O-linked N-acetylglucosamine transferase as a potential therapeutic target for metastatic gastric cancer

Joon Young Hur, Jeeyun Lee, Kyoung-Mee Kim, Sun-Ju Byeon, Inkyoung Lee, Won Ki Kang

Cancer Res (2019) 79 (13_Supplement): 3605.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3605

Published: 01 July 2019

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Journal Articles

Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)

Seung-Tae Kim, Victoria M. Raymond, Joon Oh Park, Elena Zotenko, Young Suk Park, Matthew Schultz, Won Ki Kang, Oscar Westesson, Hee-Cheol Kim, Yupeng He, Justin I. Odegaard, Stefanie A. Mortimer, William J. Greenleaf, Ariel Jaimovich, Jeeyun Lee, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 916.

DOI: https://doi.org/10.1158/1538-7445.AM2019-916

Published: 01 July 2019

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Journal Articles

Abstract CT057: Safety and efficacy of durvalumab in combination with tremelimumab in patients with advanced gastric cancer with elevated tumor interferon-γ gene signature

Geoffrey Ku, Jeeyun Lee, Heinz-Josef Lenz, Cheng Ean Chee, Takeshi Omori, Keun-Wook Lee, Yee Chao, Daniel Catenacci, Michael Gibson, Deirdre Cohen, Zev Wainberg, Philip Z. Brohawn, Peng He, Siddharth Sheth, Judson Englert, Ronan Kelly, Yung-Jue Bang

Cancer Res (2019) 79 (13_Supplement): CT057.

DOI: https://doi.org/10.1158/1538-7445.AM2019-CT057

Published: 01 July 2019

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Journal Articles

Abstract 442: Repotrectinib, a next generation TRK inhibitor, overcomes TRK resistance mutations including solvent front, gatekeeper and compound mutations

Alexander Drilon, Dayong Zhai, Wei Deng, Xin Zhang, Dong Lee, Evan Rogers, Jeffrey Whitten, Zhongdong Huang, Armin Graber, Juliet Liu, Shanna Stopatschinskaja, J. Jean Cui, Dong-Wan Kim, Byoung Chul Cho, Robert C. Doebele, Sai-Hong Ignatius Ou, Jeeyun Lee, Alice T. Shaw

Cancer Res (2019) 79 (13_Supplement): 442.

DOI: https://doi.org/10.1158/1538-7445.AM2019-442

Published: 01 July 2019

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Abstract 4215: Comprehensive investigation of programmed death receptor ligand 1 (PD-L1) expression and associated molecular features in gastric cancer patients

Xiaoqiao Liu, Jeeyun Lee, Kyoung-Mee Kim, Seung Tae Kim, Se Hoon Park, Won Ki Kang, Razvan Cristescu, Senaka Peter

Cancer Res (2018) 78 (13_Supplement): 4215.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4215

Published: 01 July 2018

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Abstract 1173: The identification of circulating tumor cells in the cerebrospinal fluid of gastric cancer patients with brain metastasis and the evaluation of intra-patient tumor heterogeneity

Jang Ho Cho, Sun Young Kim, Kyung Kim, Jusun Kim, Su Jin Lee, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Won Ki Kang, Seungtae Kim

Cancer Res (2018) 78 (13_Supplement): 1173.

DOI: https://doi.org/10.1158/1538-7445.AM2018-1173

Published: 01 July 2018

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Abstract CT111: Avelumab (anti-PD-L1) as first-line maintenance (1L mn) or second-line (2L) therapy in patients with advanced gastric or gastroesophageal junction cancer (GC/GEJC): updated phase Ib results from the JAVELIN Solid Tumor trial

Cancer Res (2018) 78 (13_Supplement): CT111.

DOI: https://doi.org/10.1158/1538-7445.AM2018-CT111

Published: 01 July 2018

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Journal Articles

Abstract 5543: Low ATM expression is associated with improved progression-free and overall survival in advanced gastric cancer patients treated with platinum-based chemotherapy

Munveer S. Bhangoo, Hubert Y. Luu, Seung Tae Kim, Jeeyun Lee, Joseph Chao, Samuel J. Klempner

Cancer Res (2018) 78 (13_Supplement): 5543.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5543

Published: 01 July 2018

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Journal Articles

Abstract 426: Targeted genome profiling in patients with advanced hepatocellular carcinoma treated with sorafenib

Wonseok Kang, Kyung Kim, Joon Hyeok Lee, Ho Yeong Lim, Woong-Yang Park, Jeeyun Lee, Yong Han Paik

Cancer Res (2017) 77 (13_Supplement): 426.

DOI: https://doi.org/10.1158/1538-7445.AM2017-426

Published: 01 July 2017

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Journal Articles

Abstract 4104: Intrinsic and acquired resistance to cetuximab in colorectal cancer patients

Steven M. Bray, Jeeyun Lee, Seung Tae Kim, Philip J. Ebert, John N. Calley, Isabella H. Wulur, Thejaswini Gopalappa, Swee Seong Wong, Hui-Rong Qian, Jason C. Ting, Jiangang Liu, Melinda D. Willard, Amit Aggarwal, Ruslan D. Novosiadly, Hee-Cheol Kim, Christoph Reinhard

Cancer Res (2017) 77 (13_Supplement): 4104.

DOI: https://doi.org/10.1158/1538-7445.AM2017-4104

Published: 01 July 2017

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Journal Articles

Abstract 3389: Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma

Cancer Res (2017) 77 (13_Supplement): 3389.

DOI: https://doi.org/10.1158/1538-7445.AM2017-3389

Published: 01 July 2017

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Journal Articles

Abstract CT007: Entrectinib, an oral pan-Trk, ROS1, and ALK inhibitor in TKI-naïve patients with advanced solid tumors harboring gene rearrangements: Updated phase I results

Alexander Drilon, Filippo G. De Braud, Salvatore Siena, Sai-Hong I. Ou, Manish Patel, Myung-Ju Ahn, Jeeyun Lee, Todd M. Bauer, Anna F. Farago, Stephen V. Liu, Natasha Reddinger, Rupal Patel, David Luo, Edna Chow Maneval, Pratik S. Multani, Robert C. Doebele, Alice T. Shaw

Cancer Res (2016) 76 (14_Supplement): CT007.

DOI: https://doi.org/10.1158/1538-7445.AM2016-CT007

Published: 15 July 2016

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NARROW

Abstract 1232: Xerna࣪ TME Panel: A pan-cancer RNA-based investigational assay designed to predict patient responses to angiogenic and immune targeted therapies

Abstract 6352: Ascites derived exosomes promote progression of advanced gastric cancers

Abstract 3206: Three-dimensional tumor angiogenesis mapping in metastatic gastric cancer patients

Abstract CT218: Phase 1/2 study of a novel HER2 targeting TLR7/8 immune-stimulating antibody conjugate (ISAC), BDC-1001, alone and in combination with pembrolizumab (pembro) in patients (pts) with HER2-expressing advanced solid tumors

Abstract OT-03-02: Phase 1/2 study of a novel HER2 targeting TLR7/8 immune-stimulating antibody conjugate (ISAC), BDC-1001, as a single agent and in combination with an immune checkpoint inhibitor in patients with advanced HER2-expressing solid tumors

Abstract 793: Association of serine/threonine kinase 11 mutations and response to programmed cell death 1 inhibitors in metastatic gastric cancer

Abstract 2912: The impact of primary tumor sidedness on the effect of regorafenib in refractory metastatic colorectal cancer

Abstract 1107: LAG3 in Solid Tumors as a Potential Novel Immunotherapy Target

Abstract 3605: O-linked N-acetylglucosamine transferase as a potential therapeutic target for metastatic gastric cancer

Abstract 916: Combined genomic and epigenomic assessment of cell-free circulating tumor DNA (ctDNA) improves assay sensitivity in early-stage colorectal cancer (CRC)

Abstract CT057: Safety and efficacy of durvalumab in combination with tremelimumab in patients with advanced gastric cancer with elevated tumor interferon-γ gene signature

Abstract 442: Repotrectinib, a next generation TRK inhibitor, overcomes TRK resistance mutations including solvent front, gatekeeper and compound mutations

Abstract 4215: Comprehensive investigation of programmed death receptor ligand 1 (PD-L1) expression and associated molecular features in gastric cancer patients

Abstract 1173: The identification of circulating tumor cells in the cerebrospinal fluid of gastric cancer patients with brain metastasis and the evaluation of intra-patient tumor heterogeneity

Abstract CT111: Avelumab (anti-PD-L1) as first-line maintenance (1L mn) or second-line (2L) therapy in patients with advanced gastric or gastroesophageal junction cancer (GC/GEJC): updated phase Ib results from the JAVELIN Solid Tumor trial

Abstract 5543: Low ATM expression is associated with improved progression-free and overall survival in advanced gastric cancer patients treated with platinum-based chemotherapy

Abstract 426: Targeted genome profiling in patients with advanced hepatocellular carcinoma treated with sorafenib

Abstract 4104: Intrinsic and acquired resistance to cetuximab in colorectal cancer patients

Abstract 3389: Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma

Abstract CT007: Entrectinib, an oral pan-Trk, ROS1, and ALK inhibitor in TKI-naïve patients with advanced solid tumors harboring gene rearrangements: Updated phase I results

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