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Jeanne Kowalski
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Journal Articles

Abstract 1271: PMEPA1 acts as a switch to modulate cooperative cellular invasion and drive NSCLC tumor progression

Tala O. Khatib, Brian A. Pedro, Christina M. Knippler, Veronika Y. Matsuk, Sarah F. Webster, Sergei Bombin, Bhakti Dwivedi, Jeanne Kowalski, Henry R. Johnston, Janna K. Mouw, Adam I. Marcus
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1271.
https://doi.org/10.1158/1538-7445.AM2024-1271
Published: 22 March 2024
View articletitled, Abstract 1271: PMEPA1 acts as a switch to modulate cooperative cellular invasion and drive NSCLC tumor progression
Journal Articles

Abstract 1298: An allosteric SHP2 inhibitor RMC-4550 induces immunogenicity in pancreatic adenocarcinoma (PDA) and enhances the cytotoxicity of CD8+ effector T cells

Agnieszka Looney, Uma Giri, Yezi Zhu, Alex Somma, Nisha Holay, Milad Soleimani, Heta Gandhi, Anna Capasso, Jeanne Kowalski, William Matsui, Carla Van Berg, S Gail Eckhardt, Todd Triplett, Kyaw Lwin Aung
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1298.
https://doi.org/10.1158/1538-7445.AM2022-1298
Published: 15 June 2022
View articletitled, Abstract 1298: An allosteric SHP2 inhibitor RMC-4550 induces immunogenicity in pancreatic adenocarcinoma (PDA) and enhances the cytotoxicity of CD8+ effector T cells
Journal Articles

Abstract 4109: Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer in part by activating lysosome biogenesis and autophagy via TFEB and TFE3

Milad Soleimani, Tamer Kaoud, Alex Somma, Jorge Bustamante, Dennis C. Wylie, Nisha Holay, Agnieszka Looney, Uma Giri, Todd Triplett, Jeanne Kowalski-Muegge, Kevin N. Dalby, S. Gail Eckhardt, Carla Van Den Berg
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4109.
https://doi.org/10.1158/1538-7445.AM2022-4109
Published: 15 June 2022
View articletitled, Abstract 4109: Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer in part by activating lysosome biogenesis and autophagy via TFEB and TFE3
Journal Articles

Abstract PS13-18: Predicting breast cancer response to neoadjuvant therapies using a mathematical model individualized with patient-specific magnetic resonance imaging data: Preliminary Results

Angela M Jarrett, David A. Hormuth, II, Anum K Syed, Chengyue Wu, John Virostko, Anna G Sorace, Julie C DiCarlo, Jeanne Kowalski, Debra Patt, Boone Goodgame, Sarah Avery, Thomas E Yankeelov
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS13-18.
https://doi.org/10.1158/1538-7445.SABCS20-PS13-18
Published: 15 February 2021
View articletitled, Abstract PS13-18: Predicting breast cancer response to neoadjuvant therapies using a mathematical model individualized with patient-specific magnetic resonance imaging data: Preliminary Results
Journal Articles

Abstract 247: Identification of the GABAA receptor in melanoma brain metastases patient tumors and demonstration that it is a viable drug target using benzodiazepine-derivatives

Milota Kaluzova, Tahseen Nasti, Hiao-Rong Chen, Lindsey Lowder, Robert Press, Havi Rosen, Manali Rupji, Laura Kallay, Rikesh Patel, Andre Burnham, Maxwell Xu, Alexandra Ross, Havva Keskin, Erin Connelly, Benjamin Izar, Cory Adamson, Jeffrey Olson, Jing Su, Walter Curran, Ragini Kudchadkar, Matthew Schniederjan, Stewart Neill, David Lawson, Michael Chan, Jeanne Kowalski, Mohammad Khan, Daniel Pomeranz Krummel, Soma Sengupta
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 247.
https://doi.org/10.1158/1538-7445.AM2019-247
Published: 01 July 2019
View articletitled, Abstract 247: Identification of the GABAA receptor in melanoma brain metastases patient tumors and demonstration that it is a viable drug target using benzodiazepine-derivatives
Journal Articles

Abstract 2623: Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death

Laura Kallay, Havva Keskin, Alexandra Ross, Manali Rupji, Olivia A. Moody, Xin Wang, Guanguan Li, Taukir Ahmed, Farjana Rashid, Michael Rajesh Stephen, Kirsten A. Cottrill, Austin Nuckois, Maxwell Xu, Deborah E. Martinson, Frank Tranghese, Yanxin Pei, James M. Cook, Jeanne Kowalski, Michael D. Taylor, Andrew Jenkins, Daniel Pomeranz Krummel, Soma Sengupta
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2623.
https://doi.org/10.1158/1538-7445.AM2019-2623
Published: 01 July 2019
View articletitled, Abstract 2623: Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death
Journal Articles

Abstract 2715: Deciphering a metabolic basis for single-agent venetoclax efficacy in t(11;14) multiple myeloma

Richa Bajpai, Abhinav Achreja, Changyong Wei, Arusha Siddiqa, Shannon M. Matulis, Vikas Gupta, Samuel K. McBrayer, Anjali Mittal, Manali Rupji, Hsiao-Rong Chen, Jeanne Kowalski, Sagar Lonial, Ajay K. Nooka, Lawrence H. Boise, Deepak Nagrath, Mala Shanmugam
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2715.
https://doi.org/10.1158/1538-7445.AM2019-2715
Published: 01 July 2019
View articletitled, Abstract 2715: Deciphering a metabolic basis for single-agent venetoclax efficacy in t(11;14) multiple myeloma
Journal Articles

Abstract 4590: Dissecting the biology of leader and follower cells in collective cancer invasion

Brian A. Pedro, Jessica Konen, Emily Summerbell, Janna K. Mouw, Manali Rupji, Bhakti Dwivedi, Jeanne Kowalski, Paula M. Vertino, Adam I. Marcus
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4590.
https://doi.org/10.1158/1538-7445.AM2019-4590
Published: 01 July 2019
View articletitled, Abstract 4590: Dissecting the biology of leader and follower cells in collective cancer invasion
Journal Articles

Abstract 2879: TYRO3 is a potential therapeutic target in pediatric acute myeloid leukemia

Sherri K. Smart, Manali Rupji, Bhakti Dwivedi, Jeanne Kowalski, Deborah DeRyckere, Douglas K. Graham
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2879.
https://doi.org/10.1158/1538-7445.AM2019-2879
Published: 01 July 2019
View articletitled, Abstract 2879: TYRO3 is a potential therapeutic target in pediatric acute myeloid leukemia
Journal Articles

Abstract 178: MYO10 aberrant methylation and overexpression in leader cells regulates lung cancer collective cell invasion and fibronectin patterning

Emily R. Summerbell, Jessica Konen, Jeanne Kowalski, Paula Vertino, Adam Marcus
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 178.
https://doi.org/10.1158/1538-7445.AM2019-178
Published: 01 July 2019
View articletitled, Abstract 178: MYO10 aberrant methylation and overexpression in leader cells regulates lung cancer collective cell invasion and fibronectin patterning
Journal Articles

Abstract 1962: Regulation of invasion by lysine demethylase 5B in non-small cell lung cancer cells

Elizabeth L. Zoeller, Jessica Konen, Joshua Bell, Emily Summerbell, Jeanne Kowalski, Adam Marcus, Paula Vertino
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1962.
https://doi.org/10.1158/1538-7445.AM2017-1962
Published: 01 July 2017
View articletitled, Abstract 1962: Regulation of invasion by lysine demethylase 5B in non-small cell lung cancer cells
Journal Articles

Abstract LB-355: Image-guided genomics reveals a symbiotic relationship between heterogeneous phenotypes in collective cancer invasion

Jessica Konen, Emily Summerbell, Kornelia Galior, Bhakti Dwivedi, Khalid Salaita, Jeanne Kowalski, Adam Marcus
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-355.
https://doi.org/10.1158/1538-7445.AM2016-LB-355
Published: 15 July 2016
View articletitled, Abstract LB-355: Image-guided genomics reveals a symbiotic relationship between heterogeneous phenotypes in collective cancer invasion
Journal Articles

Abstract A61: A novel image-guided genomics approach to dissect the mechanisms of collective cancer cell invasion

Jessica Konen, Bhakti Dwivedi, Jeanne Kowalski, Adam Marcus
Journal: Cancer Research
Cancer Res (2016) 76 (7_Supplement): A61.
https://doi.org/10.1158/1538-7445.TUMMET15-A61
Published: 26 May 2016
View articletitled, Abstract A61: A novel image-guided genomics approach to dissect the mechanisms of collective cancer cell invasion
Journal Articles

Abstract 922: Evaluating markers of cisplatin sensitivity and survival in small cell lung cancer

Taofeek Kunle Owonikoko, Guojing Zhang, Gabriel L. Sica, Zhengjia Chen, Jeffrey M. Switchenko, Sungjin Kim, Anthony A. Gal, Suresh S. Ramalingam, Xingming Deng, Michael R. Rossi, Jeanne Kowalski, Fadlo R. Khuri
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 922.
https://doi.org/10.1158/1538-7445.AM2014-922
Published: 01 October 2014
View articletitled, Abstract 922: Evaluating markers of cisplatin sensitivity and survival in small cell lung cancer
Journal Articles

CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer

Lauren E. Colbert, Aleksandra V. Petrova, Sarah B. Fisher, Brooke G. Pantazides, Matthew Z. Madden, Claire W. Hardy, Matthew D. Warren, Yunfeng Pan, Ganji P. Nagaraju, Elaine A. Liu, Burcu Saka, William A. Hall, Joseph W. Shelton, Khanjan Gandhi, Rini Pauly, Jeanne Kowalski, David A. Kooby, Bassel F. El-Rayes, Charles A. Staley, III, N. Volkan Adsay, Walter J. Curran, Jr, Jerome C. Landry, Shishir K. Maithel, David S. Yu
Journal: Cancer Research
Cancer Res (2014) 74 (10): 2677–2687.
https://doi.org/10.1158/0008-5472.CAN-13-1996
Published: 14 May 2014
View articletitled, CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer
Open the PDF for CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract B30: Class I HDACs are mediators of smoke-carcinogen induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer

Seth A. Brodie, Ge Li, Adam El-Kommos, Suresh S. Ramalingam, Mahdusmita Behera, Jeanne Kowalski, Khanjan Gandhi, Fadlo H. Khuri, Paula Vertino, Johann C. Brandes
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): B30.
https://doi.org/10.1158/1538-7445.CEC13-B30
Published: 13 May 2014
View articletitled, Abstract B30: Class I HDACs are mediators of smoke-carcinogen induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer
Journal Articles

Abstract B40: Methylation signatures specific to triple negative breast cancer subtypes

Jeanne Kowalski, Jeffery M. Switchenko, Bhakti Dwivedi, Dana Nickleach, Carlos S. Moreno
Journal: Cancer Research
Cancer Res (2013) 73 (13_Supplement): B40.
https://doi.org/10.1158/1538-7445.CEC13-B40
Published: 13 May 2014
View articletitled, Abstract B40: Methylation signatures specific to triple negative breast cancer subtypes
Journal Articles

Abstract A33: A loss of function genetic screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.

Claire W. Hardy, Brooke G. Pantazides, Khanjan Gandhi, Jerome C. Landry, Joseph W. Shelton, Shishir K. Maithel, Bassel El-Rayes, Jeanne Kowalski, David S. Yu
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A33.
https://doi.org/10.1158/1538-7445.PANCA2012-A33
Published: 03 April 2014
View articletitled, Abstract A33: A loss of function genetic screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.
Journal Articles

Abstract LB-168: A pilot clinical trial of chromodomain-helicase-DNA-binding protein 7 (CHD7) expression as a prognostic and predictive biomarker in patients with early-stage pancreatic adenocarcinoma.

Lauren E. Colbert, William A. Hall, Claire W. Hardy, Sarah B. Fisher, David S. Yu, Shishir K. Maithel, Bassel El-Rayes, Burcu Saka, N Volkan Adsay, Aleksandra Petrova, Brooke Pantazides, Jeanne Kowalski, Khanjan Gandhi, David Kooby, Charles Staley, Jerome C. Landry
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-168.
https://doi.org/10.1158/1538-7445.AM2013-LB-168
Published: 15 April 2013
View articletitled, Abstract LB-168: A pilot clinical trial of chromodomain-helicase-DNA-binding protein 7 (CHD7) expression as a prognostic and predictive biomarker in patients with early-stage pancreatic adenocarcinoma.
Journal Articles

Abstract 1767: A synthetic lethal screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.

Matthew D. Warren, Claire W. Hardy, Brooke G. Pantazides, Khanjan Gandhi, Jerome C. Landry, Joseph W. Shelton, Shishir K. Maithel, Bassel El-Rayes, Jeanne Kowalski, David S. Yu
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1767.
https://doi.org/10.1158/1538-7445.AM2013-1767
Published: 15 April 2013
View articletitled, Abstract 1767: A synthetic lethal screen identifies determinants of gemcitabine sensitivity in pancreatic cancer.