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Jeanette Wood
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Journal Articles

Abstract 2542: TG02, a novel multi-kinase inhibitor with potent anti-leukemic activity

Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart, Hannes Hentze, Chung Ong, Miah Kiat Goh, Yong-Cheng Tan, Ai Leng Liang, Yung Kiang Loh, Anthony William, Brian Dymock, Kantharaj Ethirajalu, Sara L. Zaknoen, Jeanette Wood, Francis J. Burrows
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2542.
https://doi.org/10.1158/1538-7445.AM10-2542
Published: 15 April 2010
View articletitled, Abstract 2542: TG02, a novel multi-kinase inhibitor with potent anti-leukemic activity
Journal Articles

Abstract #2924: Pharmacokinetic/Pharmacodynamic (PK/PD) relationships for novel HDAC inhibitors in a mouse xenograft HCT116 tumor model

Ramesh Jayaraman, Mohammed Khalid Pasha, Pauline Yeo, Kanda Sangthongpitag, Haishan Wang, Hannes Hentze, Veronica Diermayr, Jeanette Wood, Kantharaj Ethirajulu
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2924.
Published: 01 May 2009
View articletitled, Abstract #2924: Pharmacokinetic/Pharmacodynamic (PK/PD) relationships for novel HDAC inhibitors in a mouse xenograft HCT116 tumor model
Journal Articles

Abstract #3710: Novel potent and selective mTOR/PI3K inhibitors that inhibit tumor growth in animal models through efficient and sustained shut down of the PI3K/Akt signaling pathway

Zahid Bonday, Meredith Williams, Harish Nagaraj, Anders Poulsen, Hannes Hentze, Di Zhong Chen, Stephanie Blanchard, Stefan Hart, Kee Chuan Goh, Kay Lin Goh, Miah Kiat Goh, Ramesh Jayaraman, Ai Leng Liang, Yung Kiang Loh, Wai Chung Ong, Chang Kai Soh, Mohammad Khalid Pasha, Brian Dymock, Kantharaj Ethirajulu, Jeanette Wood
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3710.
Published: 01 May 2009
View articletitled, Abstract #3710: Novel potent and selective mTOR/PI3K inhibitors that inhibit tumor growth in animal models through efficient and sustained shut down of the PI3K/Akt signaling pathway
Journal Articles

Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics

Patrizia Sini, Ivana Samarzija, Fabienne Baffert, Amanda Littlewood-Evans, Christian Schnell, Andreas Theuer, Sven Christian, Anja Boos, Holger Hess-Stumpp, John A. Foekens, Buddy Setyono-Han, Jeanette Wood, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2008) 68 (5): 1581–1592.
https://doi.org/10.1158/0008-5472.CAN-06-4685
Published: 03 March 2008
View articletitled, Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics
Open the PDF for Inhibition of Multiple Vascular Endothelial Growth Factor Receptors (VEGFR) Blocks Lymph Node Metastases but Inhibition of VEGFR-2 Is Sufficient to Sensitize Tumor Cells to Platinum-Based Chemotherapeutics in another window
Includes: Supplementary data
Journal Articles

Role of VEGFR signaling in tumor cells

Patrizia Sini, Fabienne Baffert, Jeanette Wood, Nancy E. Hynes
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 659.
Published: 15 April 2006
View articletitled, Role of VEGFR signaling in tumor cells
Journal Articles

Antagonism of Sphingosine-1-Phosphate Receptors by FTY720 Inhibits Angiogenesis and Tumor Vascularization

Kenneth LaMontagne, Amanda Littlewood-Evans, Christian Schnell, Terence O'Reilly, Lorenza Wyder, Teresa Sanchez, Beatrice Probst, Jeannene Butler, Alexander Wood, Gene Liau, Eric Billy, Andreas Theuer, Timothy Hla, Jeanette Wood
Journal: Cancer Research
Cancer Res (2006) 66 (1): 221–231.
https://doi.org/10.1158/0008-5472.CAN-05-2001
Published: 05 January 2006
View articletitled, Antagonism of Sphingosine-1-Phosphate Receptors by FTY720 Inhibits Angiogenesis and Tumor Vascularization
Open the PDF for Antagonism of Sphingosine-1-Phosphate Receptors by FTY720 Inhibits Angiogenesis and Tumor Vascularization in another window
Journal Articles

Characterization of the effects of a small molecular weight inhibitor on IGF-I induced angiogenesis

Christian Schnell, Georg Martiny-Baron, Jeanette Wood, Francesco Hofmann, Hansgeorg Capraro, Doriano Fabbro, Pascal Furet, Carlos Garcia-Echeverria, Jurgen Mestan, Thomas Meyer, Mark A. Pearson
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 358.
Published: 01 May 2005
View articletitled, Characterization of the effects of a small molecular weight inhibitor on IGF-I induced angiogenesis
Journal Articles

AEE788: A Dual Family Epidermal Growth Factor Receptor/ErbB2 and Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor with Antitumor and Antiangiogenic Activity

Peter Traxler, Peter R. Allegrini, Ralf Brandt, Josef Brueggen, Robert Cozens, Doriano Fabbro, Konstantina Grosios, Heidi A. Lane, Paul McSheehy, Jürgen Mestan, Thomas Meyer, Careen Tang, Markus Wartmann, Jeanette Wood, Giorgio Caravatti
Journal: Cancer Research
Cancer Res (2004) 64 (14): 4931–4941.
https://doi.org/10.1158/0008-5472.CAN-03-3681
Published: 15 July 2004
View articletitled, AEE788: A Dual Family Epidermal Growth Factor Receptor/ErbB2 and Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor with Antitumor and Antiangiogenic Activity
Open the PDF for AEE788: A Dual Family Epidermal Growth Factor Receptor/ErbB2 and Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor with Antitumor and Antiangiogenic Activity in another window
Journal Articles

PTK787/ZK222584, a VEGFR tyrosine kinase inhibitor, effectively targets immature vessels in an orthotopic melanoma model

Amanda J. Littlewood-Evans, Christian Schnell, Beatrice Probst, Hans Peter Mueller, Marina Maurer, Andreas Theuer, Georg Martiny-Baron, Jeanette Wood
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 596.
Published: 01 April 2004
View articletitled, PTK787/ZK222584, a VEGFR tyrosine kinase inhibitor, effectively targets immature vessels in an orthotopic melanoma model
Journal Articles

The Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor PTK787/ZK222584 Inhibits Growth and Migration of Multiple Myeloma Cells in the Bone Marrow Microenvironment

Boris Lin, Klaus Podar, Deepak Gupta, Yu-Tzu Tai, Sigui Li, Edie Weller, Teru Hideshima, Suzanne Lentzsch, Faith Davies, Cheng Li, Ellen Weisberg, Robert L. Schlossman, Paul G. Richardson, James D. Griffin, Jeanette Wood, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Cancer Research
Cancer Res (2002) 62 (17): 5019–5026.
Published: 01 September 2002
View articletitled, The Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor PTK787/ZK222584 Inhibits Growth and Migration of Multiple Myeloma Cells in the Bone Marrow Microenvironment
Open the PDF for The Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor PTK787/ZK222584 Inhibits Growth and Migration of Multiple Myeloma Cells in the Bone Marrow Microenvironment in another window
Journal Articles

PTK787/ZK 222584, a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor, Affects the Anatomy of the Tumor Vascular Bed and the Functional Vascular Properties as Detected by Dynamic Enhanced Magnetic Resonance Imaging

Joachim Drevs, Ralph Müller-Driver, Christine Wittig, Stefan Fuxius, Norbert Esser, Harald Hugenschmidt, Moritz A. Konerding, Peter R. Allegrini, Jeanette Wood, Jürgen Hennig, Clemens Unger, Dieter Marmé
Journal: Cancer Research
Cancer Res (2002) 62 (14): 4015–4022.
Published: 15 July 2002
View articletitled, PTK787/ZK 222584, a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor, Affects the Anatomy of the Tumor Vascular Bed and the Functional Vascular Properties as Detected by Dynamic Enhanced Magnetic Resonance Imaging
Open the PDF for PTK787/ZK 222584, a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor, Affects the Anatomy of the Tumor Vascular Bed and the Functional Vascular Properties as Detected by Dynamic Enhanced Magnetic Resonance Imaging in another window
Journal Articles

Effects of PTK787/ZK 222584, a Specific Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, on Primary Tumor, Metastasis, Vessel Density, and Blood Flow in a Murine Renal Cell Carcinoma Model

Joachim Drevs, Inga Hofmann, Harald Hugenschmidt, Christine Wittig, Helmut Madjar, Marianne Müller, Jeanette Wood, Georg Martiny-Baron, Clemens Unger, Dieter Marmé
Journal: Cancer Research
Cancer Res (2000) 60 (17): 4819–4824.
Published: 01 September 2000
View articletitled, Effects of PTK787/ZK 222584, a Specific Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, on Primary Tumor, Metastasis, Vessel Density, and Blood Flow in a Murine Renal Cell Carcinoma Model
Open the PDF for Effects of PTK787/ZK 222584, a Specific Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, on Primary Tumor, Metastasis, Vessel Density, and Blood Flow in a Murine Renal Cell Carcinoma Model in another window