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Jeanette M. Wood
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Journal Articles

Abstract 3564: Design, synthesis and SAR studies leading to SB1518, a novel macrocyclic JAK2/FLT3 inhibitor in phase 2 clinical trials for myelofibrosis and lymphoma

Angeline Lee, Anthony William, Anders Poulsen, Evelyn Tan, Harish Nagaraj, Kay Lin Goh, Wai Chung Ong, Kee Chuan Goh, Mohammed Khalid Pasha, Ramesh Jayaraman, Kantharaj Ethirajulu, Jeanette M. Wood, Brian W. Dymock
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3564.
https://doi.org/10.1158/1538-7445.AM2011-3564
Published: 15 April 2011
View article titled, Abstract 3564: Design, synthesis and SAR studies leading to SB1518, a novel macrocyclic JAK2/FLT3 inhibitor in phase 2 clinical trials for myelofibrosis and lymphoma
Journal Articles

Abstract 3570: SB1518, a novel JAK2/FLT3 inhibitor for the treatment of myeloid malignancies

Stefan Hart, Kee Chuan Goh, Veronica Veronica Novotny-Diermayr, Yong Cheng Tan, Babita Madan, Chithra Amalini, Yung Kiang Loh, Lai Chun Ong, Anthony William, Angeline Lee, Anders Poulsen, Ramesh Jayaraman, Kantharaj Ethirajulu, Brian W. Dymock, Jeanette M. Wood
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3570.
https://doi.org/10.1158/1538-7445.AM2011-3570
Published: 15 April 2011
View article titled, Abstract 3570: SB1518, a novel JAK2/FLT3 inhibitor for the treatment of myeloid malignancies
Journal Articles

Abstract 3591: Discovery of SB1317: A novel small molecule macrocycle with a unique kinase inhibitory spectrum in phase 1 clinical trials for hematological malignancies

Anthony William, Stephanie Blanchard, Angeline Lee, Anders Poulsen, Eric Sun, Ee Ling Teo, Harish Nagaraj, Kay Lin Goh, Wai Chung Ong, Kee Chuan Goh, Mohammed K. Pasha, Ramesh Jayaraman, Jeanette M. Wood, Kantharaj Ethirajulu, Brian W. Dymock
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 3591.
https://doi.org/10.1158/1538-7445.AM2011-3591
Published: 15 April 2011
View article titled, Abstract 3591: Discovery of SB1317: A novel small molecule macrocycle with a unique kinase inhibitory spectrum in phase 1 clinical trials for hematological malignancies
Journal Articles

Abstract 2524: SB1518, a novel oral JAK2-FLT3 inhibitor, is efficacious in models of acute myeloid leukemia and primary leukemic cells from patients

Stefan Hart, Kee Chuan Goh, Yong Cheng Tan, Chithra Amalini, Jeanette M. Wood
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2524.
https://doi.org/10.1158/1538-7445.AM10-2524
Published: 15 April 2010
View article titled, Abstract 2524: SB1518, a novel oral JAK2-FLT3 inhibitor, is efficacious in models of acute myeloid leukemia and primary leukemic cells from patients
Journal Articles

Abstract 5436: The histone deacetylase inhibitor SB939 acts synergistically with Sorafenib in an orthotopic model of hepatucellular carcinoma

Veronica Novotny-Diermayr, Kanda Sangthongpitag, Miah Kiat Goh, Yung Kiang Loh, Lai Chun Ong, Mohammed K. Pasha, Ramesh Jayaraman, Kantharaj Ethirajulu, Jeanette M. Wood
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5436.
https://doi.org/10.1158/1538-7445.AM10-5436
Published: 15 April 2010
View article titled, Abstract 5436: The histone deacetylase inhibitor SB939 acts synergistically with Sorafenib in an orthotopic model of hepatucellular carcinoma
Journal Articles

Interstitial fluid pressure measurements in solid tumors via radio-telemetry in conscious freely moving orthotopic BN472 tumor bearing rats

Terence M. O’Reilly, Christian R. Schnell, Stephane Ferretti, Paul McSheehy, Jeanette M. Wood
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 267.
Published: 01 May 2005
View article titled, Interstitial fluid pressure measurements in solid tumors via radio-telemetry in conscious freely moving orthotopic BN472 tumor bearing rats
Journal Articles

Differential anti-vascular effects of mTOR or VEGFR pathway inhibition: A rational basis for combining RAD001 and PTK787/ZK222584

Terence M. O’Reilly, Jeanette M. Wood, Littlewood-Evans Amanda, Anne Boulay, Christian R. Schnell, Sini Patrizia, Michael Maira, Georg Martiny-Baron, Heidi A. Lane
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 715.
Published: 01 May 2005
View article titled, Differential anti-vascular effects of mTOR or VEGFR pathway inhibition: A rational basis for combining RAD001 and PTK787/ZK222584
Journal Articles

PTK787/ZK 222584, a Novel and Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, Impairs Vascular Endothelial Growth Factor-induced Responses and Tumor Growth after Oral Administration

Jeanette M. Wood, Guido Bold, Elizabeth Buchdunger, Robert Cozens, Stefano Ferrari, Jörg Frei, Francesco Hofmann, Jürgen Mestan, Helmut Mett, Terence O’Reilly, Elke Persohn, Johannes Rösel, Christian Schnell, David Stover, Andreas Theuer, Harry Towbin, Fritz Wenger, Kathie Woods-Cook, Andreas Menrad, Gerhard Siemeister, Michael Schirner, Karl-Heinz Thierauch, Martin R. Schneider, Joachim Drevs, Georg Martiny-Baron, Frank Totzke, Dieter Marmé
Journal: Cancer Research
Cancer Res (2000) 60 (8): 2178–2189.
Published: 01 April 2000
View article titled, PTK787/ZK 222584, a Novel and Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases, Impairs Vascular Endothelial Growth Factor-induced Responses and Tumor Growth after Oral Administration
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