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Jean-Yves Scoazec
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Journal Articles

Abstract 2958: SAR408701: An anti-CEACAM5-maytansinoid antibody-drug conjugate to treat CEACAM5-positive neuroendocrine prostate cancer (NEPC)

Free
Loic Poiraudeau, Bigot Ludovic, Cedric Pobel, Naoual Menssouri, Marine Aglave, Catline Nobre, Alice Bernard-Tessier, Natacha Naoun, Anna Patrikidou, Claudio Nicotra, Maud Ngocamus, Benjamin Besse, Karim Fizazi, Jean-Yves Scoazec, Anne-Marie Lefebvre, Celine Nicolazzi, Nathalie Mace, Anne-Laure Bauchet, Yohann Loriot
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 2958.
https://doi.org/10.1158/1538-7445.AM2025-2958
Published: 21 April 2025
View article titled, Abstract 2958: SAR408701: An anti-CEACAM5-maytansinoid antibody-drug conjugate to treat CEACAM5-positive neuroendocrine prostate cancer (NEPC)
Journal Articles

Abstract 738: Single-cell trajectories of metastatic urothelial cancer and individual patterns of resistance to immune checkpoint inhibitors

Free
Ronan Flippot, Amélie Roehrig, Julien Vibert, Nicolas Stransky, Luc Cabel, Kevin Mulder, Benjamin Besse, Claudio Nicotra, Maud Ngo Camus, Christophe Massard, Etienne Rouleau, Gerome Jules-Clement, Alicia Tran-Dien, Lambros Tselikas, Fabrice Andre, Jean-Yves Scoazec, Céline Vallot, Maud Kamal, Eric Letouze, Yohann Loriot
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 738.
https://doi.org/10.1158/1538-7445.AM2025-738
Published: 21 April 2025
View article titled, Abstract 738: Single-cell trajectories of metastatic urothelial cancer and individual patterns of resistance to immune checkpoint inhibitors
Journal Articles

Abstract B033: Characterizing the spatial transcriptomic landscape of Osteosarcoma from diagnosis to relapse

Free
Gaël Moquin-Beaudry, Maria Eugenia Marques Da Costa, Hanane Zair, Corentin Thuilliez, Pierre Khneisser, Nicolas Signolle, Jean-Yves Scoazec, Birgit Geoerger, Nathalie Gaspar, Antonin Marchais
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B033.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B033
Published: 05 September 2024
View article titled, Abstract B033: Characterizing the spatial transcriptomic landscape of Osteosarcoma from diagnosis to relapse
Journal Articles

Abstract PO2-18-11: Short-term Pre-OPerative Durvalumab (MEDI 4736) in early small triple negative breast cancer patients (POP-Durva)

Free
Joana Mourato Ribeiro, Isabelle Pic, Quentin Blampey, Elie Rassy, Nusaibah Ibrahimi, Laura Salabert, Olivier Trédan, Monica Arnedos, Semih Dogan, Kamar Serhal Serhal, Clementine Mahaut, Alessandro Viansone, Salim Laghouati, Barbara Pistilli, Charles-Antoine Dutertre, Magali Lacroix-Triki, Jean-Yves Scoazec, Lisa Derosa, Laurence Zitvogel, Corinne Balleyguier, Nadege Bercovici, Paul-Henry Cournede, Stefan Michiels, Fabrice André
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO2-18-11.
https://doi.org/10.1158/1538-7445.SABCS23-PO2-18-11
Published: 02 May 2024
View article titled, Abstract PO2-18-11: Short-term Pre-OPerative Durvalumab (MEDI 4736) in early small triple negative breast cancer patients (POP-Durva)
Journal Articles

Abstract 5134: Immunohistochemistry expression of membrane targets for novel therapeutic agents in RET-rearranged NSCLC

Free
Arianna Marinello, Maria Rosa Ghigna, Wael Salem Zrafi, Martina Mandarano, Isabelle Monnet, Carlo Genova, Alessandro Russo, Safae Terrisse, Giulio Metro, Jordi Remon, Anas Gazzah, Fabrice Barlesi, David Planchard, Jean-Yves Scoazec, Benjamin Besse, Mihaela Aldea
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5134.
https://doi.org/10.1158/1538-7445.AM2024-5134
Published: 22 March 2024
View article titled, Abstract 5134: Immunohistochemistry expression of membrane targets for novel therapeutic agents in RET-rearranged NSCLC
Journal Articles

Abstract 4167: Translational control of T cell exhaustion in melanoma, perspectives in therapeutics

Free
Samad Muhammadnejad, Biswendu Biswas, Ramdane Guemiri, Naima Benannoune, Jérémy Lavigne, Virginie Quidville, Jean-Yves Scoazec, Stephan Vagner, Caroline Robert
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4167.
https://doi.org/10.1158/1538-7445.AM2023-4167
Published: 04 April 2023
View article titled, Abstract 4167: Translational control of T cell exhaustion in melanoma, perspectives in therapeutics
Journal Articles

Abstract 3458: Resistance to selective FGFR inhibitors in FGFR-driven urothelial cancer

Free
Francesco Facchinetti, Antoine Hollebecque, Floriane Braye, Damien Vasseur, Yoann Pradat, Rastislav Bahleda, Cédric Pobel, Ludovic Bigot, Olivier Déas, Juan-David Florez-Arango, Giorgia Guaitoli, Hayato Mizuta, David Combarel, Lambros Tselikas, Stefan Michiels, Sergey Nikolaev, Jean-Yves Scoazec, Santiago Ponce-Aix, Benjamin Besse, Ken A. Olaussen, Yohann Loriot, Luc Friboulet
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 3458.
https://doi.org/10.1158/1538-7445.AM2023-3458
Published: 04 April 2023
View article titled, Abstract 3458: Resistance to selective FGFR inhibitors in FGFR-driven urothelial cancer
Journal Articles

Abstract 559: Expression of molecular targets for antibody-drug conjugates in patients with NSCLC and RET fusions

Free
Arianna Marinello, Maria Rosa Ghigna, Anas Gazzah, Karine Godefroy, Ludovic Lacroix, Damien Vasseur, Jordi Remon-Masip, Fabrice Barlesi, David Planchard, Jean-Yves Scoazec, Benjamin Besse, Mihaela Aldea
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 559.
https://doi.org/10.1158/1538-7445.AM2023-559
Published: 04 April 2023
View article titled, Abstract 559: Expression of molecular targets for antibody-drug conjugates in patients with NSCLC and RET fusions
Journal Articles

Abstract 4664: MatchR a preclinical platform of models resistant to innovative therapies

Free
Ludovic Bigot, Catline Nobre, Francesco Facchinetti, Loic Poiraudeau, Floriane Braye, Jonathan Sabio, Naoual Menssouri, Olivier Deas, Claudio Nicotra, Maud Ngo-Camus, Lambros Tselikas, Jean Yves Scoazec, Karim Fizazi, Siantiago Ponce, Benjamin Besse, Luc Friboulet, Yohann Loriot
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4664.
https://doi.org/10.1158/1538-7445.AM2023-4664
Published: 04 April 2023
View article titled, Abstract 4664: MatchR a preclinical platform of models resistant to innovative therapies
Journal Articles

Abstract 5714: Characterization of SWI/SNF complex gene mutations, protein expression and tumor immune microenvironment in cholangiocarcinoma

Free
Clémence Astier, Jean-Yves Scoazec, Virginie Marty, Olivia Bawa, Nicolas Signolle, Carine Ngo, Francesco Facchinetti, Antoine Hollebecque, Sophie Postel-Vinay
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5714.
https://doi.org/10.1158/1538-7445.AM2022-5714
Published: 15 June 2022
View article titled, Abstract 5714: Characterization of SWI/SNF complex gene mutations, protein expression and tumor immune microenvironment in cholangiocarcinoma
Journal Articles

Abstract 1951: Circulating tumor cell-derived explant models reveal DNA damage response-based therapeutic opportunities in non-small cell lung cancer

Free
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Deas, Judith Michels, Laur Brulle-Soumare, Stefano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, David Planchard, Jordi Remon, Santiago Ponce, Benjamin Besse, Patricia Kannouche, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1951.
https://doi.org/10.1158/1538-7445.AM2022-1951
Published: 15 June 2022
View article titled, Abstract 1951: Circulating tumor cell-derived explant models reveal DNA damage response-based therapeutic opportunities in non-small cell lung cancer
Journal Articles

Abstract 358: A prospective study of prostate cancer metastases identifies an androgen receptor activity-low, stemness program associated with resistance to androgen receptor axis inhibitors and unveils mechanisms of clonal evolution

Free
Naoual Menssouri, Loic Poiraudeau, Carole Helissey, Ludovic Bigot, Jonathan Sabio, Tony Ibrahim, Claudio Nicotra, Maud Ngocamus, Lambros Tselikas, Thierry De Baere, Etienne Rouleau, Ludovic Lacroix, Anne Chaucherau, Luc Friboulet, Ronan Flippot, Giulia Baciarello, Laurence Albiges, Emeline Colomba, Pernelle Lavaud, Stefan Michiels, Aline Maillard, Antoine Italiano, Fabrice Barlesi, Jean-Charles Soria, Jean-Yves Scoazec, christophe Massard, Benjamin Besse, Fabrice André, Karim Fizazi, Daniel Gautheret, Yohann Loriot
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 358.
https://doi.org/10.1158/1538-7445.AM2021-358
Published: 01 July 2021
View article titled, Abstract 358: A prospective study of prostate cancer metastases identifies an androgen receptor activity-low, stemness program associated with resistance to androgen receptor axis inhibitors and unveils mechanisms of clonal evolution
Journal Articles

Abstract 448: High prevalence of pathogenic germline variants in patients with oncogene-driven non-small cell lung cancer

Free
Laura Mezquita, Andrei Iurchenko, Jose Carlos Benitez, Maria Baz, Sergey Nikolaev, David Planchard, Felix Blanc-Durand, Mihaela Aldea, Patricia Martín-Romano, Yohann Loriot, Claudio Nicotra, Maud Ngocamus, Jean-Yves Scoazec, Stefan Michiels, Sophie Postel-Vinay, Julien Viot, Luc Friboulet, Antoine Italiano, Fabrice Andre, Christophe Massard, Jean-Charles Soria, Etienne Rouleau, Daniel Gautheret, Benjamin Besse
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 448.
https://doi.org/10.1158/1538-7445.AM2021-448
Published: 01 July 2021
View article titled, Abstract 448: High prevalence of pathogenic germline variants in patients with oncogene-driven non-small cell lung cancer
Journal Articles

Abstract 595: Patterns and dynamics of genome instability drive metastatic activity in non-small cell lung cancer (NSCLC) circulating tumor cell (CTC)-derived xenograft (CDX) models

Free
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Emma Pailler, Olivier Deas, Laura Mezquita, Laura Brulle-Soumare, Stephano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, Maud NgoCamus, Claudio Nicotra, David Planchard, Patricia Kannouche, Benjamin Besse, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 595.
https://doi.org/10.1158/1538-7445.AM2021-595
Published: 01 July 2021
View article titled, Abstract 595: Patterns and dynamics of genome instability drive metastatic activity in non-small cell lung cancer (NSCLC) circulating tumor cell (CTC)-derived xenograft (CDX) models
Journal Articles

Abstract 1114: Novel preclinical models of aggressive variants of castration-resistant prostate cancer

Free
Ludovic Bigot, Jonathan Sabio, Tony Ibrahim, Naoual Menssouri, Loic poiraudeau, Carole Helissey, Jean-Yves Scoazec, Zahira Merabet, Thierry De Baere, Frederic Deschamps, Maud Ngocamus, Claudio Nicotra, Etienne Rouleau, Ludovic Lacroix, Olivier Deas, Luc Friboulet, Gilles Vassal, Eric Solary, Jean-Charles Soria, Karim Fizazi, Fabrice André, Christophe Massard, Benjamin Besse, Yohann Loriot
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1114.
https://doi.org/10.1158/1538-7445.AM2020-1114
Published: 15 August 2020
View article titled, Abstract 1114: Novel preclinical models of aggressive variants of castration-resistant prostate cancer
Journal Articles

Abstract 1867: Characterization of multiple driver alterations in acquired resistance to osimertinib in EGFR-mutated lung cancer: implementation of single cell approaches

Free
Jeanne Chen, Floriane Braye, Francesco Facchinetti, Ludovic Lacroix, Jean-Yves Scoazec, Lambros Tselikas, David Planchard, Laura Mezquita, Anas Gazzah, Charles Naltet, Pernelle Lavaud, Aline Maillard, Stefan Michiels, Christophe Massard, Ken.A. Olaussen, Fabrice André, Gilles Vassal, Jean-Charles Soria, Benjamin Besse, Luc Friboulet
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1867.
https://doi.org/10.1158/1538-7445.AM2020-1867
Published: 15 August 2020
View article titled, Abstract 1867: Characterization of multiple driver alterations in acquired resistance to osimertinib in EGFR-mutated lung cancer: implementation of single cell approaches
Journal Articles

Abstract 2937: Preclinical evaluation of new therapeutic strategies on SDHB invalidated clones from human pheochromocytoma cells

Free
Constance Lamy, Julien Hadoux, Sylvere Durand, Abir Alghuzlan, Julie Riviere, Deborah Lefevre, Amaury Bongers, Jean-Yves Scoazec, Eric Baudin, Angelo Paci, Sophie Broutin
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2937.
https://doi.org/10.1158/1538-7445.AM2019-2937
Published: 01 July 2019
View article titled, Abstract 2937: Preclinical evaluation of new therapeutic strategies on SDHB invalidated clones from human pheochromocytoma cells
Journal Articles

Abstract CT081: Pediatric precision medicine program in recurrent tumors: Results of the first 500 patients included in the European MAPPYACTS molecular profiling trial

Free
Pablo Berlanga, Gudrun Schleiermacher, Ludovic Lacroix, Gaelle Pierron, Tiphaine Adam de Beaumais, Mathieu Chicard, Yasmine Iddir, Jean Yves Scoazec, Paul Freneaux, Mohamed Amine Bayar, Sophie Cotteret, Samuel Abbou, Michela Casanova, Cormac Owens, Stefan Michiels, Olivier Delattre, Gilles Vassal, Birgit Geoerger
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT081.
https://doi.org/10.1158/1538-7445.AM2019-CT081
Published: 01 July 2019
View article titled, Abstract CT081: Pediatric precision medicine program in recurrent tumors: Results of the first 500 patients included in the European MAPPYACTS molecular profiling trial
Journal Articles

Abstract 318: Mechanisms of acquired resistance to FGFR inhibitors in molecularly-selected solid tumors: A prospective cohort from the MATCH-R study

Free
Francesco Facchinetti, Rastislav Bahleda, Antoine Hollebecque, Yohann Loriot, Gonzalo Recondo, Ludovic Bigot, Ken A. Olaussen, Gilles Vassal, Stefan Michiels, Rosa L. Frias, Justine Galissant, Tony Sourisseau, Claudio Nicotra, Maud Ngo-Camus, Linda Mahjoubi, Ludovic Lacroix, Etienne Rouleau, Catherine Richon, Aurélie Abou-Lovergne, Olivier Deas, Nathalie Auger, Thierry De Baere, Frederic Deschamps, Eric Solary, Jean-Yves Scoazec, Eric Angevin, Alexander Eggermont, Fabrice André, Benjamin Besse, Jean-Paul Thiery, Jean-Charles Soria, Christophe Massard, Luc Friboulet
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 318.
https://doi.org/10.1158/1538-7445.AM2019-318
Published: 01 July 2019
View article titled, Abstract 318: Mechanisms of acquired resistance to FGFR inhibitors in molecularly-selected solid tumors: A prospective cohort from the MATCH-R study
Journal Articles

Abstract 311: Diverse biological mechanisms drive resistance to Lorlatinib in ALK-rearranged Lung Cancer

Free
Gonzalo Recondo, Laura Mezquita, David Planchard, Anas Gazzah, Francesco Facchinetti, Ludovic Bigot, Ahsan Z. Rizvi, Jean-Paul Thiery, Jean-Yves Scoazec, Rosa L. Frias, Tony Sourisseau, Linda Mahjoubi, Justine Galissant, Aurelie Abou-Lovergne, Gilles Vassal, Rastislav Bahleda, Antoine Hollebecque, Claudio Nicotra, Maud Ngocamus, Stefan Michiels, Ludovic Lacroix, Catherine Richon, Nathalie Auger, Thierry De Baere, Frederic Deschamps, Eric Solary, Ken A. Olaussen, Eric Angevin, Alexander Eggermont, Fabrice André, Christophe Massard, Jean-Charles Soria, Benjamin Besse, Luc Friboulet
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 311.
https://doi.org/10.1158/1538-7445.AM2019-311
Published: 01 July 2019
View article titled, Abstract 311: Diverse biological mechanisms drive resistance to Lorlatinib in ALK-rearranged Lung Cancer