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Jean-Yves Blay
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Journal Articles

Abstract CT083: Tumor-agnostic efficacy and safety of dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: ROAR basket study

Vivek Subbiah, Robert J. Kreitman, Zev A. Wainberg, Anas Gazzah, Ulrik Lassen, Alexander Stein, Patrick Y. Wen, Sascha Dietrich, Maja JA Jonge, Jean-Yves Blay, Antoine Italiano, Kan Yonemori, Daniel C. Cho, Filip YFL de Vos, Philippe Moreau, Elena Elez Fernandez, Jan H. Schellens, Christoph C. Zielinski, Suman Redhu, Vanessa Q. Passos, Palanichamy Ilankumaran, Yung-Jue Bang
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): CT083.
https://doi.org/10.1158/1538-7445.AM2023-CT083
Published: 14 April 2023
View article titled, Abstract CT083: Tumor-agnostic efficacy and safety of dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: ROAR basket study
Journal Articles

Abstract 6071: Whole-exome RNA sequencing of metastatic synovial sarcomas reveals heterogeneous transcriptomic profile and targetable co-alterations: Cohort study from the French Sarcoma Group

Helene Vanacker, Mehdi Brahmi, Yannick Le Meitour, Julien Bollard, Valery Attignon, Alexandra Meurgey, Myriam Jean-Denis, Laurie Tonon, Shibani Pokras, Erika Klohe, Michael Nathenson, Kristin Blouch, Ioanna Eleftheriadou, Jean-Yves Blay, Franck Tirode, Armelle Dufresne
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6071.
https://doi.org/10.1158/1538-7445.AM2023-6071
Published: 04 April 2023
View article titled, Abstract 6071: Whole-exome RNA sequencing of metastatic synovial sarcomas reveals heterogeneous transcriptomic profile and targetable co-alterations: Cohort study from the French Sarcoma Group
Journal Articles

Abstract 45: Screening somatic genomic alteration for rare adult cancers: the SPECTA-ARCAGEN project of the EORTC/EURACAN

Marie Morfouace, Aleksandra Stevovic, Julio Oliveira, Nicolas Penel, Julien Péron, Paolo G. Casali, Michael J. SECKL, Jourik A. GIETEMA, Wouter de HERDER, Lucjan WYRWICZ, Christelle de la FOUCHARDIERE, Lisa LICITRA, Nicolas GIRARD, Sophie PIPERNO-NEUMANN, Ellen KAPITEIJN, Ahmed IDBAIH, Jean-Yves Blay
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 45.
https://doi.org/10.1158/1538-7445.AM2022-45
Published: 15 June 2022
View article titled, Abstract 45: Screening somatic genomic alteration for rare adult cancers: the SPECTA-ARCAGEN project of the EORTC/EURACAN
Journal Articles

Abstract 5246: Conceptualization of core clinico-molecular variables for registries enrolling patients diagnosed with a solid tumor and profiled with next-generation sequencing (NGS)

Rodrigo Dienstmann, Clare Turnbull, Allan Hackshaw, Jean-Yves Blay, Maud Kamal, Nicolas Servant, Jan Geissler, David Tamborero, Janick Weberpals, Simon Fear, Camille Perret, Laura Perez, Martina von Meyenn, Christophe Le Tourneau
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5246.
https://doi.org/10.1158/1538-7445.AM2022-5246
Published: 15 June 2022
View article titled, Abstract 5246: Conceptualization of core clinico-molecular variables for registries enrolling patients diagnosed with a solid tumor and profiled with next-generation sequencing (NGS)
Journal Articles

Abstract 2578: High regulatory T cells infiltrate within tertiary lymphoid structure restricts response to immune checkpoint blockers in sarcomas

Florent Peyraud, Jean-Philippe Guegan, Christophe Rey, Marina Pulido, Emmanuelle Bompas, Sophie Piperno-Neumann, Christine Chevreau, Nicolas Penel, François Bertucci, Maud Toulmonde, Carine Bellera, Catherine Sautès-Fridman, Antoine Bougoüin, Coralie Cantarel, Michèle Kind, Mariella Spalato-Ceruso, Bérengère Dadone-Montaudie, Jean-Yves Blay, Wolf Herman Fridman, François Le Loarer, Alban Bessede, Antoine Italiano
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2578.
https://doi.org/10.1158/1538-7445.AM2022-2578
Published: 15 June 2022
View article titled, Abstract 2578: High regulatory T cells infiltrate within tertiary lymphoid structure restricts response to immune checkpoint blockers in sarcomas
Journal Articles

Abstract 1939: Multimodal prediction of metastatic relapse using federated deep learning outperforms state-of-the-art methods in soft-tissue sarcoma

Charles Maussion, Jean-Michel Coindre, Jean-Yves Blay, Kathryn Schutte, Axel Camara, François Le Loarer, Raul Perret, Myriam Jean-Denis, Alexandra Meurgey, Françoise Ducimetiere, Antoine Giraud, Jean-Baptiste Courrèges, Clément Gautier, Etienne Bendjebbar, Jean Du Terrail, Antoine Italiano, Marie Karanian
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1939.
https://doi.org/10.1158/1538-7445.AM2022-1939
Published: 15 June 2022
View article titled, Abstract 1939: Multimodal prediction of metastatic relapse using federated deep learning outperforms state-of-the-art methods in soft-tissue sarcoma
Journal Articles

Abstract 4094: WAYFIND-R: Delivering a high-quality real-world data (RWD) global registry of patients diagnosed with a solid tumor and profiled with next-generation sequencing (NGS)

Christophe Le Tourneau, Allan Hackshaw, Jean-Yves Blay, Jan Geissler, Clare Turnbull, Camille Perret, Olga Skatkova, Martina von Meyenn, Rodrigo Dienstmann
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 4094.
https://doi.org/10.1158/1538-7445.AM2022-4094
Published: 15 June 2022
View article titled, Abstract 4094: WAYFIND-R: Delivering a high-quality real-world data (RWD) global registry of patients diagnosed with a solid tumor and profiled with next-generation sequencing (NGS)
Journal Articles

Abstract CT025: Dabrafenib plus trametinib in BRAF V600E-mutant high-grade (HGG) and low-grade glioma (LGG)

Vivek Subbiah, Alexander Stein, Martin van den Bent, Antje Wick, Filip Y. de Vos, Nikolas von Bubnoff, Myra E. van Linde, Albert Lai, Gerald W. Prager, Mario Campone, Angelica Fasolo, Jose A. Lopez-Martin, Tae Min Kim, Ralf-Dieter Hofheinz, Jean-Yves Blay, Daniel C. Cho, Anas Gazzah, Damien Pouessel, Jeffrey Yachnin, Aislyn Boran, Paul Burgess, Palanichamy Ilankumaran, Eduard Gasal, Patrick Y. Wen
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): CT025.
https://doi.org/10.1158/1538-7445.AM2021-CT025
Published: 01 July 2021
View article titled, Abstract CT025: Dabrafenib plus trametinib in BRAF V600E-mutant high-grade (HGG) and low-grade glioma (LGG)
Journal Articles

Abstract 3191: Detection of molecular drivers in inflammatory myofibroblastic tumor: study on archival tissue from EORTC 90101 “CREATE” phase II clinical trial

Agnieszka Wozniak, Che-Jui Lee, Tom van Wezel, Jozef Sufliarsky, Hans Gelderblom, Jean-Yves Blay, Maria Debiec-Rychter, Raf Sciot, Judith V.M.G. Bovee, Patrick Schöffski
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3191.
https://doi.org/10.1158/1538-7445.AM2020-3191
Published: 15 August 2020
View article titled, Abstract 3191: Detection of molecular drivers in inflammatory myofibroblastic tumor: study on archival tissue from EORTC 90101 “CREATE” phase II clinical trial
Journal Articles

Abstract 794: Molecular analysis of archival inflammatory myofibroblastic tumor tissue samples from EORTC 90101 “CREATE” and correlation with response to crizotinib

Che-Jui Lee, Patrick Schöffski, Elodie Modave, Bram Boeckx, Diether Lambrechts, Maria Debiec-Rychter, Raf Sciot, Jozef Sufliarsky, Hans Gelderblom, Jean-Yves Blay, Agnieszka Wozniak
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 794.
https://doi.org/10.1158/1538-7445.AM2020-794
Published: 15 August 2020
View article titled, Abstract 794: Molecular analysis of archival inflammatory myofibroblastic tumor tissue samples from EORTC 90101 “CREATE” and correlation with response to crizotinib
Journal Articles

Abstract CT009: A Phase Ib study assessing biomarker modulation in soft tissue sarcoma patients treated with olaratumab followed by olaratumab plus doxorubicin

Javier Martin-Broto, Antonio Lopez Pousa, Andrew Brohl, Brian A. Van Tine, Benjamin Powers, Silvia Stacchiotti, Jean-Yves Blay, James S. Hu, Gerard J. Oakley, Hong Wang, Anna Szpurka, Donna E. Levy, Gary Mo, Matteo Ceccarelli, Robin Jones
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): CT009.
https://doi.org/10.1158/1538-7445.AM2019-CT009
Published: 01 July 2019
View article titled, Abstract CT009: A Phase Ib study assessing biomarker modulation in soft tissue sarcoma patients treated with olaratumab followed by olaratumab plus doxorubicin
Journal Articles

Abstract 1841: Integrative analysis of resistance to BRAF-targeted therapies in lung adenocarcinomas

Sandra Ortiz-Cuaran, Julien Mazières, Aurélie Swalduz, Washington René Chumbi Flores, Yohan Loriot, Virginie Westeel, Anne Pradines, Claire Tissot, Christelle Clement Duchene, Christine Raynaud, Xavier Quantin, Radj Gervais, Etienne Brain, Isabelle Monnet, Etienne Giroux Leprieur, Séverine Neymarc, Virginie Avrillon, Solène Marteau, Séverine Martinez, Gilles Clapisson, Nathalie Girerd-Chambaz, Celine Mahier, Nathalie Hoog-Labouret, Frank de Kievit, Karen Howarth, Emma Green, Clive Morris, Maurice Pérol, Jean-Yves Blay, Pierre Saintingy
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1841.
https://doi.org/10.1158/1538-7445.AM2018-1841
Published: 01 July 2018
View article titled, Abstract 1841: Integrative analysis of resistance to BRAF-targeted therapies in lung adenocarcinomas
Journal Articles

Abstract CT045: Prospective precision medicine trial of crizotinib (C) in patients (pts) with advanced, inoperable inflammatory myofibroblastic tumor (IMFT) with and without ALK alterations: EORTC phase II study 90101 "CREATE"

Patrick Schoffski, Jozef Sufliarsky, Hans Gelderblom, Jean-Yves Blay, Sandra J. Strauss, Silvia Stacchiotti, Piotr Rutkowski, Lars H. Lindner, Michael G. Leahy, Antoine Italiano, Nicolas Isambert, Maria Debiec-Rychter, Raf Sciot, Thomas Van Cann, Sandrine Marréaud, Axelle Nzokirantevye, Sandra Collette, Agnieszka Wozniak
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT045.
https://doi.org/10.1158/1538-7445.AM2018-CT045
Published: 01 July 2018
View article titled, Abstract CT045: Prospective precision medicine trial of crizotinib (C) in patients (pts) with advanced, inoperable inflammatory myofibroblastic tumor (IMFT) with and without ALK alterations: EORTC phase II study 90101 "CREATE"
Journal Articles

Abstract CT009: Results of a dose- and regimen-finding Phase Ib study of HDM201 in combination with ribociclib in patients with locally advanced or metastatic liposarcoma

Albiruni Abdul Razak, Sebastian Bauer, Jean-Yves Blay, Richard Quek, Cristina Suárez, Chia-Chi Lin, Marie L. Hütter-Krönke, Ricardo Cubedo, Stephane Ferretti, Christophe Meille, Ensar Halilovic, Giorgia Clementi, Maria Santos-Rosa, Nelson Guerreiro, Astrid Jullion, Claire Fabre, Antoine Italiano
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT009.
https://doi.org/10.1158/1538-7445.AM2018-CT009
Published: 01 July 2018
View article titled, Abstract CT009: Results of a dose- and regimen-finding Phase Ib study of HDM201 in combination with ribociclib in patients with locally advanced or metastatic liposarcoma
Journal Articles

Abstract LB-190: Combination of pembrolizumab and metronomic cyclophosphamide in patients with advanced sarcomas: a french sarcoma group study

Maud Toulmonde, Nicolas Penel, Julien Adam, Christine Chevreau, Jean-Yves Blay, Axel Le Cesne, Emmanuelle Bompas, Sophie Piperno-neumann, Sophie Cousin, Thierry Ryckewaert, Alban Bessede, François Ghiringhelli, Marina Pulido, ANTOINE ITALIANO
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-190.
https://doi.org/10.1158/1538-7445.AM2017-LB-190
Published: 01 July 2017
View article titled, Abstract LB-190: Combination of pembrolizumab and metronomic cyclophosphamide in patients with advanced sarcomas: a french sarcoma group study
Journal Articles

Abstract 2338: CD39+ Treg cooperate with a CD73-expressing Th1/Th17 subset for Adenosine-mediated immunosuppression in human breast tumors

Nicolas Gourdin, Céline Rodriguez, Selena Vigano, Isabelle Durand, Julien Faget, Camilla Jandus, Jean Yves Blay, Pedro Romero, Christine Menetrier-Caux, Christophe Caux
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2338.
https://doi.org/10.1158/1538-7445.AM2016-2338
Published: 15 July 2016
View article titled, Abstract 2338: CD39+ Treg cooperate with a CD73-expressing Th1/Th17 subset for Adenosine-mediated immunosuppression in human breast tumors
Journal Articles

Abstract PR04: Targeting tumor-asoociated macrophages with a novel anti-CSF1R antibody in cancer patients

Michael Cannarile, Sabine Hoves, Ann-Marie Broeske, Joerg Benz, Katharina Wartha, Valeria Runza, Flora Rey-Giraud, Leon P. Pradel, Friedrich Feuerhake, Irina Klaman, Tobin Jones, Ute Jucknischke, Stefan Scheiblich, Ingo H. Gorr, Antje Walz, Keelara Abiraj, Philippe Cassier, Antonio Sica, Carlos Gomez-Roca, Christophe Le Tourneau, Jean-Pierre Delord, Antoine Italiano, Hyam Levitsky, Jean-Yves Blay, Dominik Ruettinger, Carola H. Ries
Journal: Cancer Research
Cancer Res (2015) 75 (1_Supplement): PR04.
https://doi.org/10.1158/1538-7445.CHTME14-PR04
Published: 12 January 2015
View article titled, Abstract PR04: Targeting tumor-asoociated macrophages with a novel anti-CSF1R antibody in cancer patients
Journal Articles

Dsh Homolog DVL3 Mediates Resistance to IGFIR Inhibition by Regulating IGF-RAS Signaling

Shan Gao, Ilirjana Bajrami, Clare Verrill, Asha Kigozi, Djamila Ouaret, Tamara Aleksic, Ruth Asher, Cheng Han, Paul Allen, Deborah Bailey, Stephan Feller, Takeshi Kashima, Nicholas Athanasou, Jean-Yves Blay, Sandra Schmitz, Jean-Pascal Machiels, Nav Upile, Terry M. Jones, George Thalmann, Shazad Q. Ashraf, Jennifer L. Wilding, Walter F. Bodmer, Mark R. Middleton, Alan Ashworth, Christopher J. Lord, Valentine M. Macaulay
Journal: Cancer Research
Cancer Res (2014) 74 (20): 5866–5877.
https://doi.org/10.1158/0008-5472.CAN-14-0806
Published: 14 October 2014
View article titled, Dsh Homolog DVL3 Mediates Resistance to IGFIR Inhibition by Regulating IGF-RAS Signaling
Open the PDF for Dsh Homolog DVL3 Mediates Resistance to IGFIR Inhibition by Regulating IGF-RAS Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 1109: The antimicrobial peptide LL37 activates plasmacytoid dendritic cells in breast cancer

Nelly Vey, Elena Blanc, Vanja Sisirak, Sandra Thys, Céline Le Beux, Nadège Goutagny, Isabelle Treilleux, Aurélien Marabelle, Jean-Yves Blay, Christophe Caux, Nathalie Bendriss-Vermare
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1109.
https://doi.org/10.1158/1538-7445.AM2014-1109
Published: 01 October 2014
View article titled, Abstract 1109: The antimicrobial peptide LL37 activates plasmacytoid dendritic cells in breast cancer
Journal Articles

Abstract 2574: Interleukin-7 (CYT107) treatment in lymphopenic 1st line metastatic breast carcinoma patients treated with chemotherapy regimen (Capecitabine) favors the restoration of T-cell subsets number

Christine Menetrier-Caux, Isabelle Ray-Coquard, Claire Cropet, Estelle Verronese, Thomas Bachelot, Olivier Tredan, Gwenaelle Garin, Pierre Heudel, Axelle N'Kodia, Ana Delgado, Christine Bardin-Dit-Courageot, Chantal Rigal, Gilles Clapisson, Sylvie Chabaud, David Perol, Paul Rebattu, Thérèse Croughs, Nicolas Pasqual, Manuarii Manuel, Michel Morre, Jean-Yves Blay, Christophe Caux
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2574.
https://doi.org/10.1158/1538-7445.AM2014-2574
Published: 01 October 2014
View article titled, Abstract 2574: Interleukin-7 (CYT107) treatment in lymphopenic 1<sup>st</sup> line metastatic breast carcinoma patients treated with chemotherapy regimen (Capecitabine) favors the restoration of T-cell subsets number