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Jason S. Lewis
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Journal Articles

Abstract 1787: Statin therapy enhances the efficacy of HER2 directed antibody-drug conjugates in breast cancer

Bo Liu, Joshua Z. Drago, Yi Rao, Patricia R. Pereira, Anton Safonov, Antonio Marra, Mehnaj S. Ahmed, Shanu Modi, Jorge S. Reis-Filho, Filippo Montemurro, Pedram Razavi, Jason S. Lewis, Sarat Chandarlapaty
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1787.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1787
Published: 15 June 2022
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Journal Articles

Abstract P2-13-19: Statin modulation of antibody drug conjugate activity in breast cancer models and patients

Joshua Z Drago, Patricia R Pereira, Anton Safonov, Antonio Marra, Yi Rao, Bo Liu, Mehnaj Ahmed, Shanu Modi, Jorge Reis-Filho, Mark Robson, Filippo Montemurro, Pedram Razavi, Jason S Lewis, Sarat Chandarlapaty
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-13-19.
DOI: https://doi.org/10.1158/1538-7445.SABCS21-P2-13-19
Published: 15 February 2022
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Journal Articles

iNOS Regulates the Therapeutic Response of Pancreatic Cancer Cells to Radiotherapy

Patricia M.R. Pereira, Kimberly J. Edwards, Komal Mandleywala, Lukas M. Carter, Freddy E. Escorcia, Luis Felipe Campesato, Mike Cornejo, Lolkje Abma, Abu-Akeel Mohsen, Christine A. Iacobuzio-Donahue, Taha Merghoub, Jason S. Lewis
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (8): 1681–1692.
DOI: https://doi.org/10.1158/0008-5472.CAN-19-2991
Published: 15 April 2020
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Includes: Supplementary data
Journal Articles

Abstract I18: Retooling a blood-based biomarker into a theranostic agent

Jason S. Lewis
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): I18.
DOI: https://doi.org/10.1158/1538-7445.PANCA19-I18
Published: 13 December 2019
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Journal Articles

Abstract 1956: ICG pHLIP: A novel agent for fluorescence-guided surgery

Troy Crawford, Anna Moshnikova, Sean Roles, Lukas M. Carter, Jason S. Lewis, Donald M. Engelman, Oleg A. Andreev, Yana K. Reshetnyak
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1956.
DOI: https://doi.org/10.1158/1538-7445.AM2019-1956
Published: 01 July 2019
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Journal Articles

Abstract 978: Tim-4+ tissue-resident macrophages impair antitumor T-cell immunity

Andrew Chow, Sara Schad, Sai K. Sharma, Sadna Budhu, Aditi Gupta, Corrin Pimentel, Hong Zhong, Jason S. Lewis, John T. Poirier, Jedd D. Wolchok, Charles M. Rudin, Taha Merghoub
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 978.
DOI: https://doi.org/10.1158/1538-7445.AM2019-978
Published: 01 July 2019
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Journal Articles

Abstract 3694: Measuring oncogene signaling with transferrin-based PET: From bench to bedside

Michael J. Evans, Charles Truillet, Davide Ruggero, Jason S. Lewis, Rahul Aggarwal, Spencer C. Behr
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3694.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3694
Published: 01 July 2018
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Journal Articles

Abstract CT140: Phase I dose escalation study of 177Lu-HuMab-5B1 (MVT-1075) in combination with MVT-5873 as radioimmunotherapy (RIT) in subjects with relapsed / refractory pancreatic cancer or other CA19-9+ malignancies

Eileen A. O'Reilly, Christian Lohrmann, Joseph A. O'Donoghue, Erkut Borazanci, Hayley Estrella, Rebecca Teng, Terri Melink, Kirsten Dorr, Christine Kearns, Marvin Peterson, Jack Ostrowski, John Gutheil, Paul W. Maffuid, Jason S. Lewis, Wolfgang Weber
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): CT140.
DOI: https://doi.org/10.1158/1538-7445.AM2018-CT140
Published: 01 July 2018
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Journal Articles

Fc-Mediated Anomalous Biodistribution of Therapeutic Antibodies in Immunodeficient Mouse Models

Sai Kiran Sharma, Andrew Chow, Sebastien Monette, Delphine Vivier, Jacob Pourat, Kimberly J. Edwards, Thomas R. Dilling, Dalya Abdel-Atti, Brian M. Zeglis, John T. Poirier, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2018) 78 (7): 1820–1832.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-1958
Published: 01 April 2018
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Includes: Supplementary data
Journal Articles

Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer

Sai Kiran Sharma, Jacob Pourat, Dalya Abdel-Atti, Sean D. Carlin, Alessandra Piersigilli, Alexander J. Bankovich, Eric E. Gardner, Omar Hamdy, Kumiko Isse, Sheila Bheddah, Joseph Sandoval, Kristen M. Cunanan, Eric B. Johansen, Viola Allaj, Vikram Sisodiya, David Liu, Brian M. Zeglis, Charles M. Rudin, Scott J. Dylla, John T. Poirier, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2017) 77 (14): 3931–3941.
DOI: https://doi.org/10.1158/0008-5472.CAN-17-0299
Published: 13 July 2017
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Includes: Supplementary data
Journal Articles

Abstract 5204: Preclinical development of MVT-1075 as radioimmunotherapy for pancreatic cancer and other CA19-9 positive malignancies

Jacob L. Houghton, Ryan Lanning, Dayla Abdel-atti, Toni Jun, Christine M. Kearns, Michael Schlosser, Wolfgang Scholz, Jason S. Lewis, Paul W. Maffuid
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5204.
DOI: https://doi.org/10.1158/1538-7445.AM2017-5204
Published: 01 July 2017
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Journal Articles

Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma

Valentina Di Gialleonardo, Hannah N. Aldeborgh, Vesselin Miloushev, Kelly M. Folkers, Kristin Granlund, William D. Tap, Jason S. Lewis, Wolfgang A. Weber, Kayvan R. Keshari
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (11): 3113–3120.
DOI: https://doi.org/10.1158/0008-5472.CAN-16-3310
Published: 31 May 2017
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Includes: Supplementary data
Journal Articles

Abstract B44: Optimization and IND enabling investigations of MVT-2163 (89Zr-DFO-5B1) leading to First-in-Human readiness

Jacob L. Houghton, Serge K. Lyashchenko, Ritsuko Sawada, Pat Zanzonico, Scott Rudge, Wolfgang W. Scholz, Paul Maffuid, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B44.
DOI: https://doi.org/10.1158/1538-7445.PANCA16-B44
Published: 14 December 2016
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Journal Articles

Abstract LB-182: Optimized antibody modification and radiolabeling conditions for zirconium-89 immuno-PET

Eric W. Price, Jonathan M. Glaser, Kimberly J. Edwards, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-182.
DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-182
Published: 15 July 2016
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Journal Articles

Abstract 3051: Improving the efficacy of pretargeted radioimmunotherapy in preclinical murine models by utilizing bioorthogonal click chemistry

Jacob Houghton, Rosemery Membreno, Dalya Abdel-Atti, Wolfgang W. Scholz, Brian M. Zeglis, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3051.
DOI: https://doi.org/10.1158/1538-7445.AM2016-3051
Published: 15 July 2016
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Journal Articles

Abstract 4205: Targeting a variety of cancers with NOTA-derivatized pH (low) insertion peptide (pHLIP) complexes with 64Cu and 18F: What cancers are targetable

Dustin W. Demoin, Kimberly J. Edwards, Linden C. Wyatt, Mirkka Sarparanta, Jacob Pourat, Oleg A. Andreev, Yana K. Reshetnyak, Nerissa Viola-Villegas, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4205.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4205
Published: 15 July 2016
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Journal Articles

Androgen Receptor Upregulation Mediates Radioresistance after Ionizing Radiation

Daniel E. Spratt, Michael J. Evans, Brian J. Davis, Michael G. Doran, Man Xia Lee, Neel Shah, John Wongvipat, Kathryn E. Carnazza, George G. Klee, William Polkinghorn, Donald J. Tindall, Jason S. Lewis, Charles L. Sawyers
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4688–4696.
DOI: https://doi.org/10.1158/0008-5472.CAN-15-0892
Published: 15 November 2015
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Includes: Supplementary data
Journal Articles

Abstract 5444: Development of a noninvasive assay to determine drug concentration in tumor during hsp90 inhibitor therapy

Tony Taldone, Nagavarakishore Pillarsetty, Mark PS Dunphy, John F. Gerecitano, Eloisi Caldas-Lopes, Brad Beattie, Radu I. Peter, Yanlong Kang, Anna Rodina, Pengrong Yan, Erica M. DaGama Gomes, Alexander Bolaender, Christina Pressl, Blesida Punzalan, Anson Ku, Thomas Ku, Smit Shah, Mohammad Uddin, Mei H. Chen, Elmer Santos, Jacek Koziorowski, Adriana Corben, Shanu Modi, Komal Jhaveri, Oscar Lin, Efsevia Vakiani, Yelena Janjigian, Pat Zanzonico, Clifford Hudis, Steven M. Larson, Jason S. Lewis, Gabriela Chiosis
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5444.
DOI: https://doi.org/10.1158/1538-7445.AM2015-5444
Published: 01 August 2015
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Journal Articles

Abstract B25: Development of 5B1, an anti-CA19.9 monoclonal antibody, as a near-infrared fluorescent probe for intraoperative imaging of pancreatic cancer

Jacob L. Houghton, Dalya A. Abdel-Atti, Ritsuko Sawada, Wolfgang W. Scholz, Jason S. Lewis
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): B25.
DOI: https://doi.org/10.1158/1538-7445.PANCA2014-B25
Published: 30 June 2015
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Journal Articles

Abstract IA16: New methods of PET imaging pancreas cancer

Jason S. Lewis
Journal: Cancer Research
Cancer Res (2015) 75 (13_Supplement): IA16.
DOI: https://doi.org/10.1158/1538-7445.PANCA2014-IA16
Published: 30 June 2015
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