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Janusz Rak
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Journal Articles

Abstract B018: Development of DNA methylation signature predictive of response to neoadjuvant chemotherapy in osteosarcoma

Free
Philippe Jolivet, Livia Garzia, Sungmi Jung, Claudia Kleinman, Brooke Howitt, Nada Jabado, Janusz Rak, Joanna Przybyl
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B017.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B018
Published: 05 September 2024
View articletitled, Abstract B018: Development of DNA methylation signature predictive of response to neoadjuvant chemotherapy in osteosarcoma
Journal Articles

Abstract B031: Isolation and characterization of extracellular vesicles and nanoparticles from osteosarcoma cell lines: Unveiling supermeres and exomeres for therapeutic insights

Free
Marjan Khatami, Geoffroy Danieau, Lata Adnani, Laura Montermini, Nadim Tawil, Brian Meehan, Janusz Rak, Livia Garzia
Journal: Cancer Research
Cancer Res (2024) 84 (17_Supplement): B031.
https://doi.org/10.1158/1538-7445.PEDIATRIC24-B031
Published: 05 September 2024
View articletitled, Abstract B031: Isolation and characterization of extracellular vesicles and nanoparticles from osteosarcoma cell lines: Unveiling supermeres and exomeres for therapeutic insights
Journal Articles

Abstract 1385: Oncogenic regulation of autophagy and DNA emission

Free
Thupten Tsering, Kyle Dickinson, Laura Montermini, Janusz Rak, Julia Burnier
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1385.
https://doi.org/10.1158/1538-7445.AM2023-1385
Published: 04 April 2023
View articletitled, Abstract 1385: Oncogenic regulation of autophagy and DNA emission
Journal Articles

Abstract 1647: In vivo efficacy and metabolism of a new synthetized dual EGFR-DNA targeting combi-molecule in a human stem cells-derived model of glioblastoma implanted intracranially in mice

Free
Caterina Facchin, Ana Belen Fraga Timiraos, Brian Meehan, Nadia Babaa, Lata Adnani, Anne-Laure Larroque, Janusz Rak, Bertrand J Jean-Claude
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1647.
https://doi.org/10.1158/1538-7445.AM2023-1647
Published: 04 April 2023
View articletitled, Abstract 1647: In vivo efficacy and metabolism of a new synthetized dual EGFR-DNA targeting combi-molecule in a human stem cells-derived model of glioblastoma implanted intracranially in mice
Journal Articles

Abstract 5076: Pancreatic ductal adenocarcinoma associated stellate cells promote a pro-metastatic microenvironment in the liver

Free
John David Konda, Masakazu Hashimoto, Jian Zhang, Maria Celia Fernandez, Ni Wang, Stephanie Perrino, Laura Montermini, Janusz Rak, Jean-Sebastien Pelletier, Andrew M. Lowy, Pnina Brodt
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5076.
https://doi.org/10.1158/1538-7445.AM2018-5076
Published: 01 July 2018
View articletitled, Abstract 5076: Pancreatic ductal adenocarcinoma associated stellate cells promote a pro-metastatic microenvironment in the liver
Journal Articles

Abstract 4174: Differential response of non-small cell lung cancer harboring different epidermal growth factor receptor mutations to ablative radiation therapy

Free
Areej Al Rabea, Brian Meehan, Paul Daniel, Siham Sabri, Chaitanya Nirodi, Janusz Rak, Bassam Abdulkarim
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4174.
https://doi.org/10.1158/1538-7445.AM2018-4174
Published: 01 July 2018
View articletitled, Abstract 4174: Differential response of non-small cell lung cancer harboring different epidermal growth factor receptor mutations to ablative radiation therapy
Journal Articles

Abstract 1091: Procoagulant receptor tissue factor provokes the escape from brain tumor dormancy.

Free
Nathalie Magnus, Delphine Garnier, Brian Meehan, Maryam Hashemi, Tae-Hoon Lee, Chloe Milsom, Nada Jabado, Rafal Pawlinski, Nigel Mackman, Janusz Rak
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1091.
https://doi.org/10.1158/1538-7445.AM2013-1091
Published: 15 April 2013
View articletitled, Abstract 1091: Procoagulant receptor tissue factor provokes the escape from brain tumor dormancy.
Journal Articles

Abstract 1018: Epithelial-to-mesenchymal transition (EMT) alters vesiculation of cancer cells expressing oncogenic epidermal growth factor receptor (EGFR): Implications for the aggressive, procoagulant and proangiogenic properties

Free
Delphine Garnier, Chloe Milsom, Nathalie Magnus, Victoria Bentley, Tae Hoon Lee, Brian Meehan, Laura Montermini, Janusz Rak
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1018.
https://doi.org/10.1158/1538-7445.AM2012-1018
Published: 15 April 2012
View articletitled, Abstract 1018: Epithelial-to-mesenchymal transition (EMT) alters vesiculation of cancer cells expressing oncogenic epidermal growth factor receptor (EGFR): Implications for the aggressive, procoagulant and proangiogenic properties
Journal Articles

Abstract #3815: The role of microvesicles in progression and diagnosis of human glioma

Free
Khalid Al-Nedawi, Johann Micallef, Brian Meehan, Abhijit Guha, Janusz Rak
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3815.
Published: 01 May 2009
View articletitled, Abstract #3815: The role of microvesicles in progression and diagnosis of human glioma
Journal Articles

The role of tissue factor and the coagulation system in the function of tumor initiating (stem) cells

Free
Chloe Milsom, Joanne Yu, Brian Meehan, Nathalie Magnus, Linda May, Mark Anderson, Nigel Mackman, Janusz Rak
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5852.
Published: 01 May 2008
View articletitled, The role of tissue factor and the coagulation system in the function of tumor initiating (stem) cells
Journal Articles

Oncogenes, Trousseau Syndrome, and Cancer-Related Changes in the Coagulome of Mice and Humans

Free
Janusz Rak, Joanne L. Yu, James Luyendyk, Nigel Mackman
Journal: Cancer Research
Cancer Res (2006) 66 (22): 10643–10646.
https://doi.org/10.1158/0008-5472.CAN-06-2350
Published: 15 November 2006
View articletitled, Oncogenes, Trousseau Syndrome, and Cancer-Related Changes in the Coagulome of Mice and Humans
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Journal Articles

Oncogenes and Angiogenesis: Down-regulation of Thrombospondin-1 in Normal Fibroblasts Exposed to Factors from Cancer Cells Harboring Mutant Ras

Free
Wojciech Kalas, Joanne L. Yu, Chloe Milsom, Jack Rosenfeld, Robert Benezra, Paul Bornstein, Janusz Rak
Journal: Cancer Research
Cancer Res (2005) 65 (19): 8878–8886.
https://doi.org/10.1158/0008-5472.CAN-05-1479
Published: 03 October 2005
View articletitled, Oncogenes and Angiogenesis: Down-regulation of Thrombospondin-1 in Normal Fibroblasts Exposed to Factors from Cancer Cells Harboring Mutant Ras
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Journal Articles

In vitro Procoagulant Activity Induced in Endothelial Cells by Chemotherapy and Antiangiogenic Drug Combinations: Modulation by Lower-Dose Chemotherapy

Free
Li Ma, Giulio Francia, Alicia Viloria-Petit, Daniel J. Hicklin, Jeanne du Manoir, Janusz Rak, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (2005) 65 (12): 5365–5373.
https://doi.org/10.1158/0008-5472.CAN-04-3156
Published: 15 June 2005
View articletitled, In vitro Procoagulant Activity Induced in Endothelial Cells by Chemotherapy and Antiangiogenic Drug Combinations: Modulation by Lower-Dose Chemotherapy
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Journal Articles

Effect of tumor microenvironment and vitamin E on induction and enrichment of K-ras mutation in colorectal cancer cells

Free
Siranoush Shahrzad, Senji Shirasawa, Janusz Rak, Brenda Coomber
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1129.
Published: 01 May 2005
View articletitled, Effect of tumor microenvironment and vitamin E on induction and enrichment of K-ras mutation in colorectal cancer cells
Journal Articles

What Do Oncogenic Mutations Have To Do with Angiogenesis/Vascular Dependence of Tumors?

Free
Janusz Rak, Joanne L. Yu, Robert S. Kerbel, Brenda L. Coomber
Journal: Cancer Research
Cancer Res (2002) 62 (7): 1931–1934.
Published: 01 April 2002
View articletitled, What Do Oncogenic Mutations Have To Do with Angiogenesis/Vascular Dependence of Tumors?
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Journal Articles

Acquired Resistance to the Antitumor Effect of Epidermal Growth Factor Receptor-blocking Antibodies in Vivo : A Role for Altered Tumor Angiogenesis

Free
Alicia Viloria-Petit, Tania Crombet, Serge Jothy, Daniel Hicklin, Peter Bohlen, Jean Marc Schlaeppi, Janusz Rak, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (2001) 61 (13): 5090–5101.
Published: 01 July 2001
View articletitled, Acquired Resistance to the Antitumor Effect of Epidermal Growth Factor Receptor-blocking Antibodies in Vivo : A Role for Altered Tumor Angiogenesis
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Journal Articles

RB2/p130 Gene-enhanced Expression Down-Regulates Vascular Endothelial Growth Factor Expression and Inhibits Angiogenesis in Vivo

Free
Pier Paolo Claudio, Peter Stiegler, Candace M. Howard, Cristiana Bellan, Corrado Minimo, Gian Marco Tosi, Janusz Rak, Al Kovatich, Paola De Fazio, Pietro Micheli, Mario Caputi, Lorenzo Leoncini, Robert Kerbel, Giovan Giacomo Giordano, Antonio Giordano
Journal: Cancer Research
Cancer Res (2001) 61 (2): 462–468.
Published: 01 January 2001
View articletitled, RB2/p130 Gene-enhanced Expression Down-Regulates Vascular Endothelial Growth Factor Expression and Inhibits Angiogenesis in Vivo
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Journal Articles

Oncogenes and Tumor Angiogenesis: Differential Modes of Vascular Endothelial Growth Factor Up-Regulation in ras-transformed Epithelial Cells and Fibroblasts

Free
Janusz Rak, Yoshihiro Mitsuhashi, Cap Sheehan, Ami Tamir, Alicia Viloria-Petit, Jorge Filmus, Sam J. Mansour, Natalie G. Ahn, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (2000) 60 (2): 490–498.
Published: 01 January 2000
View articletitled, Oncogenes and Tumor Angiogenesis: Differential Modes of Vascular Endothelial Growth Factor Up-Regulation in ras-transformed Epithelial Cells and Fibroblasts
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Journal Articles

von Hippel-Lindau Gene-mediated Growth Suppression and Induction of Differentiation in Renal Cell Carcinoma Cells Grown as Multicellular Tumor Spheroids

Free
Blandine Lieubeau-Teillet, Janusz Rak, Serge Jothy, Othon Iliopoulos, William Kaelin, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (1998) 58 (21): 4957–4962.
Published: 01 November 1998
View articletitled, von Hippel-Lindau Gene-mediated Growth Suppression and Induction of Differentiation in Renal Cell Carcinoma Cells Grown as Multicellular Tumor Spheroids
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Journal Articles

Multiple Features of Advanced Melanoma Recapitulated in Tumorigenic Variants of Early Stage (Radial Growth Phase) Human Melanoma Cell Lines: Evidence for a Dominant Phenotype

Free
Maria Rosa Bani, Janusz Rak, Dena Adachi, Rodney Wiltshire, Jeffrey M. Trent, Robert S. Kerbel, Yaacov Ben-David
Journal: Cancer Research
Cancer Res (1996) 56 (13): 3075–3086.
Published: 01 July 1996
View articletitled, Multiple Features of Advanced Melanoma Recapitulated in Tumorigenic Variants of Early Stage (Radial Growth Phase) Human Melanoma Cell Lines: Evidence for a Dominant Phenotype
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