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Janine Arts
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Journal Articles

Abstract 189: Developing a patient-derived organoid biobank, suitable for large scale drug screenings

Lars-Eric Fielmich, Annemarie Buijs, Daniele Mori, Bas Viergever, Nihed Draoui, Anna Schepers, Mariana M. Costa e Silva, Mathijs Scholtus, Tokameh Mahmoudi, Tahlita Zuiverloon, Merel Derksen, Paul Gavine, Sylvia F. Boj, Richard Meijer, Onno Kranenburg, Janine Arts, Robert Vries
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 189.
https://doi.org/10.1158/1538-7445.AM2023-189
Published: 04 April 2023
View article titled, Abstract 189: Developing a patient-derived organoid biobank, suitable for large scale drug screenings
Journal Articles

Abstract 4388: Characterisation of molecular events across the colorectal cancer progression axis

Joke Reumers, Liesbeth Van Wesenbeeck, Eric Ciamporcero, Gerald Chu, Stan Gaj, Emanuele Palescandolo, Carl Van Hove, Karin Verstraeten, Gary Borzillo, Dianna Wu, Pieter Peeters, Janine Arts
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4388.
https://doi.org/10.1158/1538-7445.AM2017-4388
Published: 01 July 2017
View article titled, Abstract 4388: Characterisation of molecular events across the colorectal cancer progression axis
Journal Articles

Abstract A15: High-Content screen for inhibitors of cell migration in cancer metastasis using adenoviral knock-down

Remko de Pril, Annemarie Lekkerkerker, Desire van Steenhoven, Ilhem Maghrani, Tim Perera, Janine Arts, David Fischer, Richard Janssen
Journal: Cancer Research
Cancer Res (2012) 72 (13_Supplement): A15.
https://doi.org/10.1158/1538-7445.CSB12-A15
Published: 06 November 2014
View article titled, Abstract A15: High-Content screen for inhibitors of cell migration in cancer metastasis using adenoviral knock-down
Journal Articles

Abstract 2606: Rational combinations with the HDAC inhibitor, JNJ-26481585, in prostate cancer

Ian Hickson, Ann Marien, Marc Janssen, Maarten Derks, Peter King, Tinne Verhulst, Boudewijn Janssens, Hinrich Goehlmann, Ilse Van Den Wyngaert, Amy Axel, Tine Casneuf, Hilde Bohets, Angibaud Patrick, Rajendra Kumari, Sue Watson, Janine Arts, McClue Steve, Martin Page
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2606.
https://doi.org/10.1158/1538-7445.AM2011-2606
Published: 15 April 2011
View article titled, Abstract 2606: Rational combinations with the HDAC inhibitor, JNJ-26481585, in prostate cancer
Journal Articles

Abstract 5441: Preclinical assessment of the HDAC inhibitor JNJ-26481585: potent in vivo activity across a broad spectrum of human tumor xenografts

Ian Hickson, Peter King, Ann Marien, Lut Janssen, Wim Floren, Tinne Verhulst, Boudewijn Janssens, Patrick Angibaud, Martin Page, Janine Arts
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5441.
https://doi.org/10.1158/1538-7445.AM10-5441
Published: 15 April 2010
View article titled, Abstract 5441: Preclinical assessment of the HDAC inhibitor JNJ-26481585: potent <em>in vivo</em> activity across a broad spectrum of human tumor xenografts
Journal Articles

Abstract 5443: Rational combinations with the HDAC inhibitor JNJ-26481585: Prostate cancer and taxane therapy

Ian Hickson, Peter King, Ann Marien, Veronique Vreys, Marc Janssen, Tinne Verhulst, Boudewijn Janssens, Patrick Angibaud, Rajendra Kumari, Sue Watson, Martin Page, Janine Arts
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5443.
https://doi.org/10.1158/1538-7445.AM10-5443
Published: 15 April 2010
View article titled, Abstract 5443: Rational combinations with the HDAC inhibitor JNJ-26481585: Prostate cancer and taxane therapy
Journal Articles

Bortezomib Alone or in Combination with the Histone Deacetylase Inhibitor JNJ-26481585: Effect on Myeloma Bone Disease in the 5T2MM Murine Model of Myeloma

Sarah Deleu, Miguel Lemaire, Janine Arts, Eline Menu, Els Van Valckenborgh, Isabelle Vande Broek, Hendrik De Raeve, Les Coulton, Ben Van Camp, Peter Croucher, Karin Vanderkerken
Journal: Cancer Research
Cancer Res (2009) 69 (13): 5307–5311.
https://doi.org/10.1158/0008-5472.CAN-08-4472
Published: 01 July 2009
View article titled, Bortezomib Alone or in Combination with the Histone Deacetylase Inhibitor JNJ-26481585: Effect on Myeloma Bone Disease in the 5T2MM Murine Model of Myeloma
Open the PDF for Bortezomib Alone or in Combination with the Histone Deacetylase Inhibitor JNJ-26481585: Effect on Myeloma Bone Disease in the 5T2MM Murine Model of Myeloma in another window
Journal Articles

Abstract #3301: Phenotypic kinase inhibitor screening: A systems biology approach to drug discovery.

Karine Smans, Sabine De Breucker, Berthold Wroblowski, Miroslav Cik, Inez Van De Weyer, Ian Hickson, Eddy Freyne, Janine Arts, Martin Page
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3301.
Published: 01 May 2009
View article titled, Abstract #3301: Phenotypic kinase inhibitor screening: A systems biology approach to drug discovery.
Journal Articles

Abstract #1924: Preclinical and clinical pharmacodynamic activity of JNJ-26854165: A novel hdm2 antagonist in clinical development

Janine Arts, Karine Smans, Luc Andries, Wim Floren, Peter King, Luc van Nuffel, Ilse Goris, Hinrich Goehlmann, Brendan Rooney, Peter Palmer, Lut de Bie, Kees Bol, Silvija Kraljevic, Sen Hong Zhuang, Martin Page, Josep Tabernero, José Baselga, Luc Dirix, Patrick Schöffski, Hans Winkler
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1924.
Published: 01 May 2009
View article titled, Abstract #1924: Preclinical and clinical pharmacodynamic activity of JNJ-26854165: A novel hdm2 antagonist in clinical development
Journal Articles

Abstract #5631: JNJ-26481585: a novel \#8220;second-generation\#8221; oral pan-Histone Deacetylase (HDAC) in clinical development shows preclinical anti-tumor activity against prostate cancer

Peter King, Ann Marien, Lut Janssen, Wim Floren, Rajendra Kumari, Sue Watson, Luc Andries, Patrick Angibaud, Martin Page, Janine Arts
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5631.
Published: 01 May 2009
View article titled, Abstract #5631: JNJ-26481585: a novel \#8220;second-generation\#8221; oral pan-Histone Deacetylase (HDAC) in clinical development shows preclinical anti-tumor activity against prostate cancer
Journal Articles

JNJ-26854165 - a novel hdm2 antagonist in clinical development showing broad-spectrum preclinical antitumor activity against solid malignancies

Janine Arts, Martin Page, Annemie Valckx, Christine Blattner, Roman Kulikov, Wim Floren, Luc van Nuffel, Lut Janssen, Peter King, Stefan Masure, Karine Smans, Peter Verhasselt, Hinrich Goehlmann, Yannick Ligny, Delphine Lardeau, Imre Csoka, Luc Andries, Dirk Brehmer, Eddy Freyne, Eugen Leo, Michel Janicot, Christophe Meyer, Jean Lacrampe, Bruno Schoentjes
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1592.
Published: 01 May 2008
View article titled, JNJ-26854165 - a novel hdm2 antagonist in clinical development showing broad-spectrum preclinical antitumor activity against solid malignancies
Journal Articles

Preclinical evaluation of the novel HDAC-inhibitor JNJ-26481585 in multiple myeloma reveals strong anti-tumor activity

Thorsten Stuehmer, Janine Arts, Peter King, Johanna Borawski, Martin Page, Eugen Leo, Ralf Bargou
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 738.
Published: 01 May 2008
View article titled, Preclinical evaluation of the novel HDAC-inhibitor JNJ-26481585 in multiple myeloma reveals strong anti-tumor activity
Journal Articles

JNJ-26481585: A novel “second-generation” oral pan-Histone Deacetylase (HDAC) inhibitor showing broad-spectrum preclinical antitumor activity against solid and haematological malignancies

Janine Arts, Ann Marien, Peter King, Wim Floren, Ann Belien, Lut Janssen, Isabelle Pilatte, Bruno Roux, Laurence Decrane, Ron Gilissen, Eugene Cox, Luc Andries, Marc Du Jardin, Peter Hellemans, Martin Page, Michel Janicot, Kristof van Emelen, Patrick Angibaud
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2444.
Published: 01 May 2008
View article titled, JNJ-26481585: A novel “second-generation” oral pan-Histone Deacetylase (HDAC) inhibitor showing broad-spectrum preclinical antitumor activity against solid and haematological malignancies
Journal Articles

Effect of an hdm-2 antagonist peptide inhibitor on cell cycle progression in p53-deficient H1299 human lung carcinoma cells

Ann Vanderborght, Annemie Valckx, Thierry Grand-Perret, Stefanie De Schepper, Jacky Van Dun, Lut Janssen, Michel Janicot, Janine Arts
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 858.
Published: 01 May 2005
View article titled, Effect of an hdm-2 antagonist peptide inhibitor on cell cycle progression in p53-deficient H1299 human lung carcinoma cells
Journal Articles

Antiproliferative effect of BRCA1-associated protein 1 (BAP1) knockout and overexpression on tumor cell lines

Vadim V. Markovtsov, Yonchu Jenkins, Wayne Lang, Poonam Sharma, Justin Warner, Yasumichi Hitoshi, Mark Bennett, Susan Molineaux, Donald Payan, Jorge Vialard, Janine Arts, Michel Janicot
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 186.
Published: 01 April 2004
View article titled, Antiproliferative effect of BRCA1-associated protein 1 (BAP1) knockout and overexpression on tumor cell lines