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Abstract A036 The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states

Cancer Res (2024) 84 (17_Supplement): A036.

https://doi.org/10.1158/1538-7445.PEDIATRIC24-A036

Published: 05 September 2024

View articletitled, Abstract A036 The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states

Journal Articles

Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo

Cancer Res (2022) 82 (12_Supplement): 668.

https://doi.org/10.1158/1538-7445.AM2022-668

Published: 15 June 2022

View articletitled, Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo

Journal Articles

Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

Cancer Res (2021) 81 (7): 1667–1680.

https://doi.org/10.1158/0008-5472.CAN-20-0177

Published: 01 April 2021

View articletitled, Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

Includes: Supplementary data

Journal Articles

Abstract B15: Genomic classification and prognosis in rhabdomyosarcoma: A report from the Children’s Oncology Group, the Institute of Cancer Research, and the National Cancer Institute

Cancer Res (2020) 80 (14_Supplement): B15.

https://doi.org/10.1158/1538-7445.PEDCA19-B15

Published: 15 July 2020

View articletitled, Abstract B15: Genomic classification and prognosis in rhabdomyosarcoma: A report from the Children’s Oncology Group, the Institute of Cancer Research, and the National Cancer Institute

Journal Articles

Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death

Johannes Ommer, Joanna L. Selfe, Marco Wachtel, Eleanor M. O'Brien, Dominik Laubscher, Michaela Roemmele, Stephanie Kasper, Olivier Delattre, Didier Surdez, Gemma Petts, Anna Kelsey, Janet Shipley, Beat W. Schäfer

Cancer Res (2020) 80 (4): 832–842.

https://doi.org/10.1158/0008-5472.CAN-19-1479

Published: 14 February 2020

View articletitled, Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death

Includes: Supplementary data

Journal Articles

Abstract 2975: Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors

Emmy DG Fleuren, Sam Jones, Jessica Frankum, Chris Williamson, Malini Menon, Janet Shipley, Alan Ashworth, Winette van der Graaf, Christopher J. Lord

Cancer Res (2018) 78 (13_Supplement): 2975.

https://doi.org/10.1158/1538-7445.AM2018-2975

Published: 01 July 2018

View articletitled, Abstract 2975: Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors

Journal Articles

ATR Is a Therapeutic Target in Synovial Sarcoma

Samuel E. Jones, Emmy D.G. Fleuren, Jessica Frankum, Asha Konde, Chris T. Williamson, Dragomir B. Krastev, Helen N. Pemberton, James Campbell, Aditi Gulati, Richard Elliott, Malini Menon, Joanna L. Selfe, Rachel Brough, Stephen J. Pettitt, Wojciech Niedzwiedz, Winette T.A. van der Graaf, Janet Shipley, Alan Ashworth, Christopher J. Lord

Cancer Res (2017) 77 (24): 7014–7026.

https://doi.org/10.1158/0008-5472.CAN-17-2056

Published: 14 December 2017

View articletitled, ATR Is a Therapeutic Target in Synovial Sarcoma

Includes: Supplementary data

Journal Articles

Abstract 2986: Meta-analysis of whole exome sequencing data reveals the mutational spectrum of testicular germ cell tumors

Kevin Litchfield, Richard S. Houlston, Robert Huddart, Brenda Summersgill, Janet Shipley, Clare Turnbull

Cancer Res (2015) 75 (15_Supplement): 2986.

https://doi.org/10.1158/1538-7445.AM2015-2986

Published: 01 August 2015

View articletitled, Abstract 2986: Meta-analysis of whole exome sequencing data reveals the mutational spectrum of testicular germ cell tumors

Journal Articles

Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

Monika Ehnman, Edoardo Missiaglia, Erika Folestad, Joanna Selfe, Carina Strell, Khin Thway, Bertha Brodin, Kristian Pietras, Janet Shipley, Arne Östman, Ulf Eriksson

Cancer Res (2013) 73 (7): 2139–2149.

https://doi.org/10.1158/0008-5472.CAN-12-1646

Published: 02 April 2013

View articletitled, Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

Includes: Supplementary data

Journal Articles

Abstract 5343: Aberrant activation of hedgehog signaling confers a poor prognosis in embryonal and fusion gene negative alveolar rhabdomyosarcoma

Arne Zibat, Edoardo Missiaglia, Albert Rosenberger, Kathy Pritchard-Jones, Janet Shipley, Heidi Hahn, Simone Fulda

Cancer Res (2011) 71 (8_Supplement): 5343.

https://doi.org/10.1158/1538-7445.AM2011-5343

Published: 15 April 2011

View articletitled, Abstract 5343: Aberrant activation of hedgehog signaling confers a poor prognosis in embryonal and fusion gene negative alveolar rhabdomyosarcoma

Journal Articles

Role for Amplification and Expression of Glypican-5 in Rhabdomyosarcoma

Daniel Williamson, Joanna Selfe, Tony Gordon, Yong-Jie Lu, Kathy Pritchard-Jones, Kasumi Murai, Phil Jones, Paul Workman, Janet Shipley

Cancer Res (2007) 67 (1): 57–65.

https://doi.org/10.1158/0008-5472.CAN-06-1650

Published: 08 January 2007

View articletitled, Role for Amplification and Expression of Glypican-5 in Rhabdomyosarcoma

Includes: Supplementary data

Journal Articles

Large scale genomic homozygosity and non-seminomatous testicular germ tumour development

Yong-Jie Lu, Jinshu Yang, Elodie Noel, xueying Mao, Spyros Skoulakis, Tracy Chaplin, Manoj Raghavan, Trisha Purkis, Sakunthala Kudahetti, Dan Berney, Janet Shipley, Timothy Oliver, Bryan Young

Cancer Res (2006) 66 (8_Supplement): 985.

Published: 15 April 2006

View articletitled, Large scale genomic homozygosity and non-seminomatous testicular germ tumour development

Journal Articles

Genomic and Expression Profiling of Human Spermatocytic Seminomas: Primary Spermatocyte as Tumorigenic Precursor and DMRT1 as Candidate Chromosome 9 Gene

Leendert H.J. Looijenga, Remko Hersmus, Ad J.M. Gillis, Rolph Pfundt, Hans J. Stoop, Ruud J.H.L.M. van Gurp, Joris Veltman, H. Berna Beverloo, Ellen van Drunen, Ad Geurts van Kessel, Renee Reijo Pera, Dominik T. Schneider, Brenda Summersgill, Janet Shipley, Alan McIntyre, Peter van der Spek, Eric Schoenmakers, J. Wolter Oosterhuis

Cancer Res (2006) 66 (1): 290–302.

https://doi.org/10.1158/0008-5472.CAN-05-2936

Published: 05 January 2006

View articletitled, Genomic and Expression Profiling of Human Spermatocytic Seminomas: Primary Spermatocyte as Tumorigenic Precursor and DMRT1 as Candidate Chromosome 9 Gene

Journal Articles

Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

Yong-Jie Lu, Jinshu Yang, Elodie Noel, Spyros Skoulakis, Tracy Chaplin, Manoj Raghavan, Trisha Purkis, Alan Mcintyre, Sakunthala C. Kudahetti, Mahmoud Naase, Dan Berney, Janet Shipley, R. Timothy D. Oliver, Bryan D. Young

Cancer Res (2005) 65 (20): 9137–9141.

https://doi.org/10.1158/0008-5472.CAN-05-1697

Published: 17 October 2005

View articletitled, Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

Journal Articles

Amplification and Overexpression of the KIT Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults

Alan McIntyre, Brenda Summersgill, Beata Grygalewicz, Ad J.M. Gillis, J. Stoop, Ruud J.H.L.M. van Gurp, Nening Dennis, Cyril Fisher, Robert Huddart, Colin Cooper, Jeremy Clark, J. Wolter Oosterhuis, Leendert H.J. Looijenga, Janet Shipley

Cancer Res (2005) 65 (18): 8085–8089.

https://doi.org/10.1158/0008-5472.CAN-05-0471

Published: 15 September 2005

View articletitled, Amplification and Overexpression of the KIT Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults

Journal Articles

HOXB13 - a potential marker for prostate cancer

Sandra E. Edwards, Penny Flohr, Jeremy Clark, Colin Campbell, Simon Rogers, Gyula Kovacs, Sameer Jhavar, Janet Shipley, Colin S. Cooper

Cancer Res (2005) 65 (9_Supplement): 844.

Published: 01 May 2005

View articletitled, HOXB13 - a potential marker for prostate cancer

Journal Articles

Gene expression profiling for prognosis and diagnosis in human sarcomas.

Yin-Fai Lee, Megan John, Alison Falconer, Sandra Edwards, Jeremy Clark, Penny Flohr, Toby Roe, Rubin Wang, Janet Shipley, Robert J. Grimer, D. Chas Mangham, J. Meirion Thomas, Cyril Fisher, Ian Judson, Colin S. Cooper

Cancer Res (2005) 65 (9_Supplement): 20.

Published: 01 May 2005

View articletitled, Gene expression profiling for prognosis and diagnosis in human sarcomas.

Journal Articles

A Gene Expression Signature Associated with Metastatic Outcome in Human Leiomyosarcomas

Cancer Res (2004) 64 (20): 7201–7204.

https://doi.org/10.1158/0008-5472.CAN-04-1673

Published: 15 October 2004

View articletitled, A Gene Expression Signature Associated with Metastatic Outcome in Human Leiomyosarcomas

Includes: Supplementary data

Journal Articles

Molecular cytogenetics and physical mapping: A concerted strategy towards defining disease genes in rhabdomyosarcoma.

Ian Roberts, Elena Cattaneo, Nicola Foster, Anthony Gordon, Elisabeth Nacheva, Janet Shipley, Nicholas Coleman

Cancer Res (2004) 64 (7_Supplement): 793.

Published: 01 April 2004

View articletitled, Molecular cytogenetics and physical mapping: A concerted strategy towards defining disease genes in rhabdomyosarcoma.

Journal Articles

Impact of SYT-SSX Fusion Type on the Clinical Behavior of Synovial Sarcoma: A Multi-Institutional Retrospective Study of 243 Patients

Marc Ladanyi, Cristina R. Antonescu, Denis H. Leung, James M. Woodruff, Akira Kawai, John H. Healey, Murray F. Brennan, Julia A. Bridge, James R. Neff, Frederic G. Barr, Jeffrey D. Goldsmith, John S. J. Brooks, John R. Goldblum, Syed Z. Ali, Janet Shipley, Colin S. Cooper, Cyril Fisher, Björn Skytting, Olle Larsson

Cancer Res (2002) 62 (1): 135–140.

Published: 01 January 2002

View articletitled, Impact of SYT-SSX Fusion Type on the Clinical Behavior of Synovial Sarcoma: A Multi-Institutional Retrospective Study of 243 Patients

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Abstract A036 The Stratified Medicine Paediatrics programme for cancers of childhood: Cell free DNA and serial tumour sequencing identifies subtype specific evolution and epigenetic states

Abstract 668: A MYOD-SKP2 axis boosts oncogenic properties of fusion negative rhabdomyosarcoma and is counteracted by neddylation inhibition in vitro and in vivo

Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

Abstract B15: Genomic classification and prognosis in rhabdomyosarcoma: A report from the Children’s Oncology Group, the Institute of Cancer Research, and the National Cancer Institute

Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death

Abstract 2975: Synthetic lethality in synovial sarcoma: SS18-SSX fusions and DNA damage response (DDR) inhibitors

ATR Is a Therapeutic Target in Synovial Sarcoma

Abstract 2986: Meta-analysis of whole exome sequencing data reveals the mutational spectrum of testicular germ cell tumors

Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

Abstract 5343: Aberrant activation of hedgehog signaling confers a poor prognosis in embryonal and fusion gene negative alveolar rhabdomyosarcoma

Role for Amplification and Expression of Glypican-5 in Rhabdomyosarcoma

Large scale genomic homozygosity and non-seminomatous testicular germ tumour development

Genomic and Expression Profiling of Human Spermatocytic Seminomas: Primary Spermatocyte as Tumorigenic Precursor and DMRT1 as Candidate Chromosome 9 Gene

Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

Amplification and Overexpression of the KIT Gene Is Associated with Progression in the Seminoma Subtype of Testicular Germ Cell Tumors of Adolescents and Adults

HOXB13 - a potential marker for prostate cancer

Gene expression profiling for prognosis and diagnosis in human sarcomas.

A Gene Expression Signature Associated with Metastatic Outcome in Human Leiomyosarcomas

Molecular cytogenetics and physical mapping: A concerted strategy towards defining disease genes in rhabdomyosarcoma.

Impact of SYT-SSX Fusion Type on the Clinical Behavior of Synovial Sarcoma: A Multi-Institutional Retrospective Study of 243 Patients

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