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Janet L. Stein
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Journal Articles

Abstract 2176: Mutational profiling of premalignant breast microbiopsies

Daniela Nachmanson, Mark F. Evans, Joseph Steward, Adam Officer, Huazhen Yao, Thomas J. O'Keefe, Farnaz Hasteh, Gary S. Stein, Kristen Jepsen, Donald L. Weaver, Gillian L. Hirst, Brian L. Sprague, Laura J. Esserman, Alexander Borowsky, Janet L. Stein, Olivier Harismendy
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2176.
https://doi.org/10.1158/1538-7445.AM2021-2176
Published: 01 July 2021
View article titled, Abstract 2176: Mutational profiling of premalignant breast microbiopsies
Journal Articles

Abstract GS2-01: The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ

Olivier Harismendy, Daniela Nachmanson, Mark F. Evans, Hidetoshi Mori, Adam Officer, Christina Yau, Joseph Steward, Huazhen Yao, Thomas O'Keefe, Farnaz Hasteh, Gary S. Stein, Kristen Jepsen, Michael Campbell, Donald L. Weaver, Gillian L. Hirst, Brian L. Sprague, Laura J. Esserman, Jonathan A. Gordon, Alexander Borowsky, Janet L. Stein
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): GS2-01.
https://doi.org/10.1158/1538-7445.SABCS20-GS2-01
Published: 15 February 2021
View article titled, Abstract GS2-01: The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ
Journal Articles

Abstract 4462: RUNX1 global binding and gene regulation in mammary epithelial cells revealed novel Runx1 mediated cellular activities

Deli Hong, Andrew J. Fritz, Coralee E. Tye, Natalie A. Page, Joseph R. Boyd, Jane B. Lian, Janet L. Stein, Gary S. Stein
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4462.
https://doi.org/10.1158/1538-7445.AM2018-4462
Published: 01 July 2018
View article titled, Abstract 4462: RUNX1 global binding and gene regulation in mammary epithelial cells revealed novel Runx1 mediated cellular activities
Journal Articles

Abstract LB-251: Development of a circulating microRNA risk signature predictive of breast cancer diagnosis among high-risk women

Nicholas H. Farina, Jon E. Ramsey, Melissa E. Sands, Tiffany J. Rounds, David J. Shirley, Thomas P. Ahern, Janet L. Stein, Gary S. Stein, Jane B. Lian, Marie E. Wood
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-251.
https://doi.org/10.1158/1538-7445.AM2017-LB-251
Published: 01 July 2017
View article titled, Abstract LB-251: Development of a circulating microRNA risk signature predictive of breast cancer diagnosis among high-risk women
Journal Articles

Abstract 5534: Runx1 possesses anti-tumor activity and inhibits stemness in breast cancer cells

Deli Hong, Andrew J, Fritz, Kristiaan Finstad, Mark P. Fitzgerald, Janet L. Stein, Jane Lian, Gary S. Stein
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5534.
https://doi.org/10.1158/1538-7445.AM2017-5534
Published: 01 July 2017
View article titled, Abstract 5534: Runx1 possesses anti-tumor activity and inhibits stemness in breast cancer cells
Journal Articles

Abstract 3142: Circulating microRNAs can identify cancer-free women at risk for breast cancer

Nicholas H. Farina, Jon E. Ramsey, Melissa E. Sands, Tiffany J. Rounds, Janet L. Stein, Gary S. Stein, Jane B. Lian, Marie E. Wood
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3142.
https://doi.org/10.1158/1538-7445.AM2016-3142
Published: 15 July 2016
View article titled, Abstract 3142: Circulating microRNAs can identify cancer-free women at risk for breast cancer
Journal Articles

Abstract B34: Secreted microRNAs from prostate cancer cells: Novel therapeutic targets

Nicholas H. Farina, Cody J. Callahan, Coralee E. Tye, Joseph R. Boyd, Gary S. Stein, Janet L. Stein, Jane B. Lian
Journal: Cancer Research
Cancer Res (2016) 76 (6_Supplement): B34.
https://doi.org/10.1158/1538-7445.NONRNA15-B34
Published: 13 May 2016
View article titled, Abstract B34: Secreted microRNAs from prostate cancer cells: Novel therapeutic targets
Journal Articles

Abstract 4003: Serum miRNAs associated with prostate cancer: correlation to deregulated signaling pathways

Nicholas H. Farina, Jon E. Ramsey, Areg Zingiryan, Steven Ades, Mark K. Plante, Gary S. Stein, Janet L. Stein, Jane B. Lian, Scott D. Perrapato
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4003.
https://doi.org/10.1158/1538-7445.AM2015-4003
Published: 01 August 2015
View article titled, Abstract 4003: Serum miRNAs associated with prostate cancer: correlation to deregulated signaling pathways
Journal Articles

Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease

Hanna Taipaleenmäki, Gillian Browne, Jacqueline Akech, Jozef Zustin, Andre J. van Wijnen, Janet L. Stein, Eric Hesse, Gary S. Stein, Jane B. Lian
Journal: Cancer Research
Cancer Res (2015) 75 (7): 1433–1444.
https://doi.org/10.1158/0008-5472.CAN-14-1026
Published: 31 March 2015
View article titled, Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
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Includes: Supplementary data
Journal Articles

Abstract 3524: Unraveling the dichotomy of Runx1 in breast cancer

Gillian Browne, Nicole M. Bishop, Jason R. Dobson, Sharath C. Madasu, Farina H. Nicholas, Maria L. La Porta, Dana Frederick, Jennifer L. Colby, Leslie M. Shaw, Justine Landis, Janet L. Stein, Jane B. Lian, Gary S. Stein
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3524.
https://doi.org/10.1158/1538-7445.AM2014-3524
Published: 01 October 2014
View article titled, Abstract 3524: Unraveling the dichotomy of Runx1 in breast cancer
Journal Articles

Integrin αvβ6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2

Anindita Dutta, Jing Li, Huimin Lu, Jacqueline Akech, Jitesh Pratap, Tao Wang, Brad J. Zerlanko, Thomas J. FitzGerald, Zhong Jiang, Ruth Birbe, John Wixted, Shelia M. Violette, Janet L. Stein, Gary S. Stein, Jane B. Lian, Lucia R. Languino
Journal: Cancer Research
Cancer Res (2014) 74 (5): 1598–1608.
https://doi.org/10.1158/0008-5472.CAN-13-1796
Published: 02 March 2014
View article titled, Integrin αvβ6 Promotes an Osteolytic Program in Cancer Cells by Upregulating MMP2
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Includes: Supplementary data
Journal Articles

Bookmarking Target Genes in Mitosis: A Shared Epigenetic Trait of Phenotypic Transcription Factors and Oncogenes?

Sayyed K. Zaidi, Rodrigo A. Grandy, Cesar Lopez-Camacho, Martin Montecino, Andre J. van Wijnen, Jane B. Lian, Janet L. Stein, Gary S. Stein
Journal: Cancer Research
Cancer Res (2014) 74 (2): 420–425.
https://doi.org/10.1158/0008-5472.CAN-13-2837
Published: 16 January 2014
View article titled, Bookmarking Target Genes in Mitosis: A Shared Epigenetic Trait of Phenotypic Transcription Factors and Oncogenes?
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Journal Articles

Abstract 4009: Hypoxia potentiates Runx2-mediated increased Bcl-2 expression in prostate cancer resulting in apoptosis resistance

Gillian Browne, Heather McCook, Louise Ming, Janet L. Stein, Gary S. Stein, Jane B. Lian, Stephanie R. McKeown, Jenny Worthington
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4009.
https://doi.org/10.1158/1538-7445.AM2012-4009
Published: 15 April 2012
View article titled, Abstract 4009: Hypoxia potentiates Runx2-mediated increased Bcl-2 expression in prostate cancer resulting in apoptosis resistance
Journal Articles

Frequent Attenuation of the WWOX Tumor Suppressor in Osteosarcoma Is Associated with Increased Tumorigenicity and Aberrant RUNX2 Expression

Kyle C. Kurek, Sara Del Mare, Zaidoun Salah, Suhaib Abdeen, Hussain Sadiq, Suk-hee Lee, Eugenio Gaudio, Nicola Zanesi, Kevin B. Jones, Barry DeYoung, Gail Amir, Mark Gebhardt, Matthew Warman, Gary S. Stein, Janet L. Stein, Jane B. Lian, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5577–5586.
https://doi.org/10.1158/0008-5472.CAN-09-4602
Published: 30 June 2010
View article titled, Frequent Attenuation of the WWOX Tumor Suppressor in Osteosarcoma Is Associated with Increased Tumorigenicity and Aberrant RUNX2 Expression
Open the PDF for Frequent Attenuation of the WWOX Tumor Suppressor in Osteosarcoma Is Associated with Increased Tumorigenicity and Aberrant RUNX2 Expression in another window
Includes: Supplementary data
Journal Articles

Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a miR-24/MKP-7/MAPK Network

Sayyed K. Zaidi, Christopher R. Dowdy, Andre J. van Wijnen, Jane B. Lian, Azra Raza, Janet L. Stein, Carlo M. Croce, Gary S. Stein
Journal: Cancer Research
Cancer Res (2009) 69 (21): 8249–8255.
https://doi.org/10.1158/0008-5472.CAN-09-1567
Published: 28 October 2009
View article titled, Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a miR-24/MKP-7/MAPK Network
Open the PDF for Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a miR-24/MKP-7/MAPK Network in another window
Includes: Supplementary data
Journal Articles

Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression

Jitesh Pratap, Karen M. Imbalzano, Jean M. Underwood, Nathalie Cohet, Karthiga Gokul, Jacqueline Akech, Andre J. van Wijnen, Janet L. Stein, Anthony N. Imbalzano, Jeffrey A. Nickerson, Jane B. Lian, Gary S. Stein
Journal: Cancer Research
Cancer Res (2009) 69 (17): 6807–6814.
https://doi.org/10.1158/0008-5472.CAN-09-1471
Published: 31 August 2009
View article titled, Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression
Open the PDF for Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression in another window
Includes: Supplementary data
Journal Articles

Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells

Jitesh Pratap, John J. Wixted, Tripti Gaur, Sayyed K. Zaidi, Jason Dobson, Karthiga Devi Gokul, Sadiq Hussain, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein, Jane B. Lian
Journal: Cancer Research
Cancer Res (2008) 68 (19): 7795–7802.
https://doi.org/10.1158/0008-5472.CAN-08-1078
Published: 30 September 2008
View article titled, Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells
Open the PDF for Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells in another window
Includes: Supplementary data
Journal Articles

MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival

Ricardo Medina, Sayyed K. Zaidi, Chang-Gong Liu, Janet L. Stein, Andre J. vanWijnen, Carlo M. Croce, Gary S. Stein
Journal: Cancer Research
Cancer Res (2008) 68 (8): 2773–2780.
https://doi.org/10.1158/0008-5472.CAN-07-6754
Published: 15 April 2008
View article titled, MicroRNAs 221 and 222 Bypass Quiescence and Compromise Cell Survival
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Includes: Supplementary data
Journal Articles

The HiNF-P/p220NPAT Cell Cycle Signaling Pathway Controls Nonhistone Target Genes

Ricardo Medina, Margaretha van der Deen, Angela Miele-Chamberland, Rong-Lin Xie, Andre J. van Wijnen, Janet L. Stein, Gary S. Stein
Journal: Cancer Research
Cancer Res (2007) 67 (21): 10334–10342.
https://doi.org/10.1158/0008-5472.CAN-07-1560
Published: 01 November 2007
View article titled, The HiNF-P/p220<sup>NPAT</sup> Cell Cycle Signaling Pathway Controls Nonhistone Target Genes
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Journal Articles

Runx2 in breast and prostate cancer cells: Roles in adhesion, invasion and tumor activity in bone

Jitesh Pratap, Jacqueline Akech, Krystin Bedard, Michael Breen, Andre J. Van Wijnen, Janet L. Stein, Gary S. Stein, Lucia Languino, Jane B. Lian
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 934–935.
Published: 15 April 2006
View article titled, Runx2 in breast and prostate cancer cells: Roles in adhesion, invasion and tumor activity in bone