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Janet A. Sawicki
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Journal Articles

Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth

Yu-Hung Huang, Weidan Peng, Narumi Furuuchi, Jacquelyn Gerhart, Kelly Rhodes, Neelanjan Mukherjee, Masaya Jimbo, Gregory E. Gonye, Jonathan R. Brody, Robert C. Getts, Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2016) 76 (6): 1549–1559.
https://doi.org/10.1158/0008-5472.CAN-15-2073
Published: 14 March 2016
View article titled, Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth
Open the PDF for Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth in another window
Includes: Supplementary data
Journal Articles

Abstract 5133: The RNA-binding protein HuR facilitates proliferation and metastasis in human pancreatic ductal adenocarcinoma

Masaya Jimbo, Fernando F. Blanco, Brad Screnci, Gabriela Cosma, Vitali Alexeev, Yu-Hung Huang, Jordan M. Winter, Charles J. Yeo, Janet A. Sawicki, Jonathan R. Brody
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5133.
https://doi.org/10.1158/1538-7445.AM2015-5133
Published: 01 August 2015
View article titled, Abstract 5133: The RNA-binding protein HuR facilitates proliferation and metastasis in human pancreatic ductal adenocarcinoma
Journal Articles

Abstract 3542: Inhibition of HuR effectively suppresses ovarian tumor growth in mice

Janet A. Sawicki, Yu-Hung Huang, Jonathan R. Brody, Robert C. Getts, Kelly Rhodes, Jackie Gerhart
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3542.
https://doi.org/10.1158/1538-7445.AM2015-3542
Published: 01 August 2015
View article titled, Abstract 3542: Inhibition of HuR effectively suppresses ovarian tumor growth in mice
Journal Articles

Abstract 700: Systemic administration of DNA nanoparticles containing the diphtheria toxin gene reduces pancreatic tumor load in mice

Janet A. Sawicki, Weidan Peng, Kelly Rhodes, Robert Getts
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 700.
https://doi.org/10.1158/1538-7445.AM2014-700
Published: 01 October 2014
View article titled, Abstract 700: Systemic administration of DNA nanoparticles containing the diphtheria toxin gene reduces pancreatic tumor load in mice
Journal Articles

HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells

Shruti Lal, Richard A. Burkhart, Neil Beeharry, Vikram Bhattacharjee, Eric R. Londin, Joseph A. Cozzitorto, Carmella Romeo, Masaya Jimbo, Zoë A. Norris, Charles J. Yeo, Janet A. Sawicki, Jordan M. Winter, Isidore Rigoutsos, Timothy J. Yen, Jonathan R. Brody
Journal: Cancer Research
Cancer Res (2014) 74 (4): 1128–1140.
https://doi.org/10.1158/0008-5472.CAN-13-1915
Published: 16 February 2014
View article titled, HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells
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Includes: Multimedia, Supplementary data
Journal Articles

Abstract A51: Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice

Xiaoling Xiong, Leszek Kotula, Anna Chorzalska, Patrycja Dubielecka, Julie White, Yogindra Vedvyas, Cyrus V. Hedvat, Adriana Haimovitz-Friedman, Jason A. Koutcher, Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2012) 72 (4_Supplement): A51.
https://doi.org/10.1158/1538-7445.PRCA2012-A51
Published: 09 May 2013
View article titled, Abstract A51: Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice
Journal Articles

Abstract 5630: Nanotherapeutic silencing of HuR: Targeting a tumor-promoting response in ovarian cancer

Janet A. Sawicki, Yu-Hung Huang, Charles J. Yeo, Radhika P. Gogoi, Kevin Love, Daniel G. Anderson, Agnieszka K. Witkiewicz, Jonathan R. Brody
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5630.
https://doi.org/10.1158/1538-7445.AM2012-5630
Published: 15 April 2012
View article titled, Abstract 5630: Nanotherapeutic silencing of HuR: Targeting a tumor-promoting response in ovarian cancer
Journal Articles

Abstract LB-231: Therapeutic targeting of multiple pancreatic tumor promoting-pathways in vivo: nanotherapeutic silencing of HuR

Jonathan R. Brody, Agnieszka K. Witkiewicz, Fengzhi Liu, Charles J. Yeo, Shuo Qio, Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-231.
https://doi.org/10.1158/1538-7445.AM2011-LB-231
Published: 15 April 2011
View article titled, Abstract LB-231: Therapeutic targeting of multiple pancreatic tumor promoting-pathways in vivo: nanotherapeutic silencing of HuR
Journal Articles

Abstract 2: Naked CanScript, an 18-base pair sequence, has tumor cell-specific promoter activity in vivo: Implications for targeted gene therapy

Janet A. Sawicki, Yu-Hung Huang, Joseph Cozzitorto, Robert Langer, Daniel G. Anderson, Jonathan R. Brody
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2.
https://doi.org/10.1158/1538-7445.AM10-2
Published: 15 April 2010
View article titled, Abstract 2: Naked CanScript, an 18-base pair sequence, has tumor cell-specific promoter activity in vivo: Implications for targeted gene therapy
Journal Articles

Nanoparticle-Delivered Suicide Gene Therapy Effectively Reduces Ovarian Tumor Burden in Mice

Yu-Hung Huang, Gregory T. Zugates, Weidan Peng, David Holtz, Charles Dunton, Jordan J. Green, Naushad Hossain, Michael R. Chernick, Robert F. Padera, Jr., Robert Langer, Daniel G. Anderson, Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2009) 69 (15): 6184–6191.
https://doi.org/10.1158/0008-5472.CAN-09-0061
Published: 29 July 2009
View article titled, Nanoparticle-Delivered Suicide Gene Therapy Effectively Reduces Ovarian Tumor Burden in Mice
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Includes: Supplementary data
Journal Articles

Fetal Microchimerism and Cancer

Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2008) 68 (23): 9567–9569.
https://doi.org/10.1158/0008-5472.CAN-08-3008
Published: 01 December 2008
View article titled, Fetal Microchimerism and Cancer
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Journal Articles

Nanoparticle-delivery of diphtheria toxin DNA inhibits ovarian tumor growth

Janet A. Sawicki, Yu-Hung Huang, Weidan Peng, Daniel Anderson, Robert Langer
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 495.
Published: 15 April 2006
View article titled, Nanoparticle-delivery of diphtheria toxin DNA inhibits ovarian tumor growth
Journal Articles

Elevated histone acetyltransferase activity in TRAMP mouse adenocarcinomas

Cheryl A. Hobbs, Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 361.
Published: 01 April 2004
View article titled, Elevated histone acetyltransferase activity in TRAMP mouse adenocarcinomas
Journal Articles

Nanoparticle-delivered suicide gene causes prostate tumor regression

Weidan Peng, Daniel G. Anderson, Robert S. Langer, Janet A. Sawicki
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 272.
Published: 01 April 2004
View article titled, Nanoparticle-delivered suicide gene causes prostate tumor regression
Journal Articles

Increased Frequency of Spontaneous Skin Tumors in Transgenic Mice Which Overexpress Ornithine Decarboxylase

Louis Megosh, Susan K. Gilmour, Dan Rosson, Aléjandro Peralta Soler, Manfred Blessing, Janet A. Sawicki, Thomas G. O'Brien
Journal: Cancer Research
Cancer Res (1995) 55 (19): 4205–4209.
Published: 01 October 1995
View article titled, Increased Frequency of Spontaneous Skin Tumors in Transgenic Mice Which Overexpress Ornithine Decarboxylase
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